NCT05374980

The Effects of Yogurt on Gut Microbiome and Metabolism in H. Pylori.

The Effects of Fermented Milk Product With Probiotic on Helicobacter Pylori Infection, Gut Microbiome and Metabolism.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 51 (actual)
• Sponsor: Taichung Veterans General Hospital · Academic / Other
• Sex: All
• Age: 20 Years – 70 Years
• Healthy volunteers: Accepted

Summary

Helicobacter pylori is a common pathogen causing upper gastrointestinal diseases including gastric ulcer and gastric cancer. Recent epidemiological findings have also shown that it is also related to colon cancer, metabolic syndrome, gut dysbiosis, glycemic control and insulin resistance. The aim of this study is to investigate whether the gut microbiota and insulin resistance of patients with H. pylori infection are abnormal. In addition, whether drinking fermented milk product with probiotic reduces Helicobacter pylori, improves gut microbiota, and increases butyrate-producing bacteria and insulin resistance.

Conditions

• Probiotic
• Gut Microbiota
• Helicobacter Pylori Infection
• Insulin Resistance

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Yogurt	Drink a bottle of 200ml yogurt every morning and evening for 8 weeks
DIETARY_SUPPLEMENT	Placebo	Drink a bottle of 200ml placebo every morning and evening for 8 weeks

Timeline

• Start date: 2022-01-01
• Primary completion: 2023-02-16
• Completion: 2023-02-16
• First posted: 2022-05-16
• Last updated: 2023-04-12

Locations

1 site across 1 country: Taiwan