Trials / Completed
CompletedNCT04103424
Mitochondrial Remodeling After Exercise
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 31 (actual)
- Sponsor
- Oregon State University · Academic / Other
- Sex
- All
- Age
- 18 Years – 45 Years
- Healthy volunteers
- Accepted
Summary
Regulation of mitochondrial health in overweight and obese individuals may be impaired. The purpose of this study is to identify impairments in regulation of mitochondrial health within skeletal muscle and to determine if short-term exercise training (2-weeks) can reverse such impairments. The investigator's hypothesis is that pathways that serve to degrade poorly functioning mitochondria in overweight and obese individuals are down-regulated, but that short-term exercise training can restore these pathways to improve skeletal muscle mitochondrial function.
Conditions
- Overweight and Obesity
- Insulin Resistance
- Metabolic Disease
- Mitochondrial Metabolism
- Sedentary Lifestyle
Interventions
| Type | Name | Description |
|---|---|---|
| BEHAVIORAL | Short-term Exercise Training | Participants will perform 2-weeks of supervised exercise training on a stationary bike. |
Timeline
- Start date
- 2019-08-23
- Primary completion
- 2020-11-25
- Completion
- 2022-12-03
- First posted
- 2019-09-25
- Last updated
- 2024-02-13
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT04103424. Inclusion in this directory is not an endorsement.