Trials / Conditions / Acute Respiratory Failure

Acute Respiratory Failure

267 registered clinical trials studyying Acute Respiratory Failure — 46 currently recruiting.

Status	Trial	Sponsor	Phase
Not Yet Recruiting	Examination of Personalized SpO2 Targets NCT07536984	Vanderbilt University Medical Center	N/A
Not Yet Recruiting	Evaluation of Perfusion and Ventilation Distribution in Children: a Pilot Study. NCT07532811	Hospices Civils de Lyon	N/A
Recruiting	Exhaled Breath Condensate Analysis in Mechanically Ventilated Patients NCT06189924	The Institute of Molecular and Translational Medicine, Czech Republic	—
Not Yet Recruiting	The Caribbean Registry of Extracorporeal Membrane Oxygenation (ECMO) From the University Hospital in Martiniqu NCT07351435	University of Genova	—
Not Yet Recruiting	Early Inflammatory-Immune Stratification and Precision Glucocorticoid Intervention in Acute Respiratory Failur NCT07357935	Qingyuan Zhan	Phase 1 / Phase 2
Not Yet Recruiting	Eduction in ImmunoSuppressive Regimen Among Kidney Transplant Recipients Patients Admitted to the Intensive Ca NCT06881927	University Hospital, Strasbourg, France	Phase 4
Not Yet Recruiting	Brain-lung Interaction During Acute Respiratory Failure NCT07279831	Assistance Publique - Hôpitaux de Paris	—
Completed	ICU Admission Diagnoses and ICU Mortality NCT07369206	Ataturk University	—
Not Yet Recruiting	Diaphragm Response in Elderly for Acute Monitoring NCT07132268	Centre Hospitalier de Bethune	—
Enrolling By Invitation	Hyperangulated Versus Standard Geometry Laryngoscope Blade Trial NCT07223762	Vanderbilt University Medical Center	N/A
Recruiting	Acute DYSPnea in the Emergency Department: Diagnostic Value of Point-of-care UltraSound NCT07324980	Università degli Studi del Piemonte Orientale Amedeo Avogadro	—
Recruiting	Comparison of Two SpO2 Targets With Two Different Oximeters - Impact on FiO2 During Nasal High Flow Oxygen The NCT07168213	Laval University	N/A
Recruiting	Evaluating the Safety and Performance of the MiniLung Petite Kit in Neonatal and Pediatric Patients With Acute NCT06750536	Xenios AG	—
Recruiting	Simulation Trial of Telemedical Support for Paramedics NCT06441760	Boston Medical Center	N/A
Recruiting	Continous Positive Airway Pressure (CPAP) Support for Acute Hypoxemic Respiratory Failure in Burkina Faso NCT06912360	Université NAZI BONI	N/A
Recruiting	Virtual Reality in ICU - PARTNER NCT06876168	Kirby Mayer	—
Enrolling By Invitation	Tube Size Randomized Trial During Emergency Tracheal Intubation NCT06939361	Vanderbilt University Medical Center	N/A
Recruiting	Validation Study of the EMILY AI Device in Acute and Chronic Respiratory Failure NCT06952816	Aether Tech S.L.	N/A
Recruiting	Waveform Capnography Compared to Colorimetric Carbon Dioxide Detection During Tracheal Intubation of Criticall NCT06934876	Brian Driver	—
Not Yet Recruiting	Physiological Effects of Nebulized Salbutamol in Acute Respiratory Failure Patients on HFNC NCT06815679	Università degli Studi di Ferrara	Phase 2 / Phase 3
Recruiting	External Validation of the BREF Models NCT06669312	Istituto Clinico Humanitas	—
Not Yet Recruiting	Nutritional Intake in Patients on Noninvasive Ventilation: a Prospective Observational Study NCT06740981	Università degli Studi del Piemonte Orientale Amedeo Avogadro	—
Completed	Electrical Impedance Tomography-derived Flow Index During Spontaneous Breathing Trial Stratifies the Risk of R NCT06876792	Ruijin Hospital	—
Not Yet Recruiting	Exploring the Correlations of Lung Ultrasound with Delirium and Outcomes in Acute GEriatrics World: a Multicen NCT06670118	University of Milano Bicocca	—
Recruiting	CORALINE - Correlation Between Physiological and Clinical Variables and Failure of Non-Invasive Respiratory Su NCT06989385	University of Modena and Reggio Emilia	—
Completed	CT Indices Analysis in ICU Pneumonia Patients With Acute Respiratory Failure (CT:Computed Tomography, ICU: Int NCT06651931	Kocaeli University	—
Completed	Ventilator Settings for Bronchoscopy During Mechanical Ventilation: a Randomized Controlled Study NCT06562725	Centre Hospitalier Arras	N/A
Recruiting	Investigating Dyadic Expectations About ARF Survivorship (IDEAS) NCT06401239	Johns Hopkins University	—
Withdrawn	Stability of Driving Pressure Changes During "Best Positive End Expiratory Pressure (PEEP)" Trial NCT05958862	University of Alabama at Birmingham	—
Completed	Asymmetric High-flow Nasal Cannula (HFNC) vs Standard HFNC for Post Extubation High-risk Group NCT06301035	Samsung Medical Center	N/A
Completed	The Tele-Rehab MV Cluster Stepped-Wedge Randomized Clinical Trial NCT06343545	Hospital Israelita Albert Einstein	N/A
Recruiting	Hyperangulated vs Macintosh Blades for Intubation With Videolaryngoscopy in ICU NCT06322719	Hospital Clinico Universitario de Santiago	N/A
Recruiting	Infusion of Prostacyclin vs Placebo for 72-hours in Mechanically Ventilated Patients With Acute Respiratory Fa NCT06319274	Pär Johansson	Phase 2
Recruiting	Closed-loop syncHronization vErsuS convenTional Synchronization in sPontaneously Breathing Adult Nonivasive ve NCT06357780	Başakşehir Çam & Sakura City Hospital	N/A
Recruiting	Assessment of Ventilation Parameters for Extubation Prediction in ICU NCT06531005	Ankara University	—
Enrolling By Invitation	A Study of Communication Between Clinicians, Patients, and Families in the Intensive Care Unit (ICU) NCT06042621	University of Wisconsin, Madison	—
Unknown	Prevalence of an Early Success of Non-invasive Ventilation in the Emergency Departement. NCT06213623	Poitiers University Hospital	—
Unknown	The Burden of Acute Respiratory Failure in Chinese ICUs: a National Cohort Study NCT06213779	Southeast University, China	—
Completed	Personalized Decision-Aid to Guide Tracheostomy and Prolonged Mechanical Ventilation Decision-Making NCT07223918	Denver Health and Hospital Authority	—
Unknown	Comfort of Patients Under Non Invasive Ventilation According to the Mask NCT06212180	Assistance Publique - Hôpitaux de Paris	—
Not Yet Recruiting	NIV Versus HFO for Acute Exacerbations of Interstitial Lung Diseases NCT06182956	ADIR Association	N/A
Active Not Recruiting	Predicting High-Flow Nasal Cannula Failure Using an Electrical Impedance Tomography-Derived Index: A Multicent NCT07366541	Ruijin Hospital	—
Completed	Surface Mechanomyography Using a Parasternal Patch to Measure and Detect Respiratory Drive and Effort NCT06046898	University Hospital, Angers	N/A
Recruiting	Global Physiotherapy in ICU Patients With High Risk Extubation Failure NCT05423301	University Hospital, Bordeaux	N/A
Recruiting	Decremental Esophageal Catheter Filling Volume Titration For Transpulmonary Pressure Measurement NCT06051292	Dr. Behcet Uz Children's Hospital	N/A
Recruiting	A Clinical Study for Developing Artificial Intelligence(AI)-Based Clustering Model for Personalized Medicine i NCT06479421	Samsung Medical Center	—
Unknown	Thigh Muscle Mass and Muscle Wasting in Patients in the Emergency Department NCT05978154	Korea University Ansan Hospital	—
Recruiting	Comparing High-flow Nasal Cannula Oxygen and Noninvasive Ventilation to Standard Oxygenation in Non-selected I NCT05812911	University Hospital, Montpellier	N/A
Unknown	Transbronchial Lung Cryobiopsy in Undiagnosed Acute Respiratory Failure NCT05754866	China-Japan Friendship Hospital	N/A
Unknown	Tracheal Positive Pressure During High Flow Nasal Oxygen Administration in Critically Ill Patients: a Physiolo NCT05467332	Azienda Sanitaria-Universitaria Integrata di Udine	—
Unknown	Effect of End-inspiratory Airway Pressure Measurements on the Risk of VILI in Ventilated Patients NCT05991258	University of Padova	—
Completed	Generating Evidence in ECMO Ventilation Strategies NCT05708365	Duke University	N/A
Active Not Recruiting	The Maximizing Extubation Outcomes Through Educational and Organizational Research (METEOR) Trial NCT05523479	University of Pittsburgh	N/A
Unknown	V/Q Matching in Pressure Support Ventilation NCT05781802	Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone Palermo	—
Completed	High Flow During Weaning From Mechanical Ventilation NCT05577221	Assistance Publique - Hôpitaux de Paris	N/A
Unknown	Evaluation of Regional Ventilation Distribution Using Electrical Impedance Tomography During Weaning From Mech NCT05726513	Università degli Studi di Ferrara	N/A
Recruiting	Practice of Oxygenation and Respiratory Support During Fiberoptic Bronchoscopy NCT05681962	University Magna Graecia	—
Unknown	Evaluation of Regional Ventilation Distribution in Patients Affected by Abdominal Sepsis After Emergent Laparo NCT05726500	Università degli Studi di Ferrara	N/A
Recruiting	Closed-loop Synchronization Versus Conventional Synchronization NCT05731024	Dr. Behcet Uz Children's Hospital	N/A
Active Not Recruiting	Efficacy and Safety of High-Flow Nasal Cannula Versus Noninvasive Ventilation for Pulmonary Arterial Hypertens NCT06582459	The First People's Hospital of Neijiang	—
Unknown	VICOR Study-High Frequency Chest Wall Oscillations (HFCWO) in Patients With Acute Respiratory Failure and Hype NCT05751707	Raffaele Scala	N/A
Terminated	Intermediate Normal Versus High Normal Oxygen Levels in the Emergency Department for Severe Traumatic Brain In NCT05464277	Evangelismos Hospital	N/A
Unknown	Neural Pressure Support for Low Pulmonary Compliance NCT05566652	Policlinico Hospital	N/A
Unknown	A Prospective Observational Cohort Study of Awake Prone Position Ventilation Strategy in Patients With Acute R NCT05570903	First Affiliated Hospital of Zhejiang University	—
Completed	Non-invasive Respiratory Monitoring During SBT NCT05295186	University of Bari	—
Recruiting	Study on Ventilation Distribution With Electrical Impedance Tomography for Paediatric Respiratory Failure NCT05347563	Hospices Civils de Lyon	—
Recruiting	Viscoelastic Testing Guided Tissue Plasminogen Activator Treatment in Acute Respiratory Failure NCT05540834	South West Sydney Local Health District	Phase 2
Recruiting	Neural Pressure Support, Synchrony and Respiratory Muscle Unloading NCT05670093	Karolinska Institutet	N/A
Unknown	High Frequency Percussive Ventilation in COVID-19 Patients NCT05358184	University Magna Graecia	N/A
Completed	Bivalirudin Versus Enoxaparin in Critically Ill COVID-19 Patients NCT05334654	University Magna Graecia	N/A
Completed	Randomized Trial of Sedative Choice for Intubation NCT05277896	Vanderbilt University Medical Center	Phase 4
Enrolling By Invitation	Effect of Ketamine and Etomidate During RSI on Long Term Outcomes NCT06179485	Vanderbilt University Medical Center	—
Completed	Human Algorithm Interactions for Acute Respiratory Failure Diagnosis NCT06098950	University of Michigan	N/A
Unknown	Single Breath Counting Test for Acute Respiratory Failure in Emergency Department NCT06257784	Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria	—
Completed	DirEct Versus VIdeo LaryngosCopE Trial NCT05239195	Vanderbilt University Medical Center	N/A
Unknown	Individualization Flow in Patients Treated With High Flow Nasal Therapy (iFLOW) NCT05401474	Hospital Universitari Vall d'Hebron Research Institute	N/A
Completed	Pragmatic Trial Examining Oxygenation Prior to Intubation NCT05267652	Vanderbilt University Medical Center	N/A
Unknown	High Flow Nasal Cannula Versus High Velocity Nasal Insufflation in Covid-19 NCT05216640	Assiut University	N/A
Unknown	Explore Potential Plasma and BALF Immunometabolic and Lipidomic Biomarkers for Identifying ARDS Endotypes NCT05451342	Peking Union Medical College Hospital	—
Completed	Assessing Ventilator Safety in Patients on Pressure-Support Ventilation NCT05125952	Duke University	N/A
Unknown	Pronation During Veno-venous Extra Corporeal Membrane Oxygenation NCT05198986	University Magna Graecia	—
Unknown	High Frequency Percussive Ventilation in Hypersecretive Tracheostomized Patients NCT05200507	University Magna Graecia	—
Unknown	Lung Aeration After Flexible Bronchoscopy in Intubated Critically Ill Patients NCT05200494	University Magna Graecia	N/A
Completed	Hypercapnic Acute Respiratory Failure in the ICU : the YETI Study NCT04304339	French Society for Intensive Care	—
Completed	Effects of Body Position and Recruiting Maneuver on Lung Aeration Assessed Through Ultrasound in Patients Intu NCT05209477	Azienda Ospedaliera di Perugia	N/A
Active Not Recruiting	Helmet NIV in Acute Respiratory Failure NCT05022173	Hamilton Health Sciences Corporation	N/A
Completed	Influence of Vibroacoustic Therapy Modes on the Course of Coronavirus Infection NCT05143372	Astana Medical University	N/A
Completed	Predict Transpulmonary Pressure Through ZAM NCT05378802	Southeast University, China	N/A
Completed	Propofol Versus Ketamine for Rapid Sequence Intubation in Critically Ill Patients NCT05092152	Federal University of São Paulo	Phase 2
Recruiting	Blue Protocol and Eko Artificial Intelligence Are Best (BEA-BEST) NCT05144633	University of Louisville	—
Completed	Impact of Dyspnea, Regional Lung Ventilation, and Diaphragmatic Function During de Novo Acute Respiratory Fail NCT04961437	Assistance Publique - Hôpitaux de Paris	—
Terminated	Ganciclovir to Prevent Reactivation of Cytomegalovirus in Patients With Acute Respiratory Failure and Sepsis NCT04706507	Fred Hutchinson Cancer Center	Phase 3
Completed	Closed-loop Oxygen Control for High Flow Nasal Therapy NCT04965844	Hospital Universitari Vall d'Hebron Research Institute	N/A
Completed	A Check-list Including Lung Ultrasound for ED Patients With ARF NCT04791241	Centre Hospitalier Metropole Savoie	N/A
Completed	Implementation of Nudges to Promote Utilization of Low Tidal Volume Ventilation (INPUT) Study NCT04663802	University of Pennsylvania	N/A
Completed	HFNT vs. COT in COVID-19 NCT04655638	Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone Palermo	N/A
Completed	Standard Oxygen Versus High Flow Nasal Cannula Oxygen Therapy in Patients With Acute Hypoxemic Respiratory Fai NCT04468126	Poitiers University Hospital	N/A
Unknown	Empirical Steroids and/or Antifungals in Immunocompromised Patients With Acute Respiratory Failure From Undete NCT04680884	Assistance Publique - Hôpitaux de Paris	Phase 3
Completed	Low Dose Morphine to Relieve Dyspnea in Acute Respiratory Failure (OPIDYS) NCT04358133	Assistance Publique - Hôpitaux de Paris	Phase 2
Terminated	RENOVATE Fibrosis:HFNC Versus NIPPV in Acute Respiratory Failure in Patients With Pulmonary Fibrosis NCT04253405	Hospital do Coracao	N/A
Unknown	Effects of a New Interface for NIV on Respiratory Drive NCT04619667	University Magna Graecia	N/A
Unknown	Physiological Effects of a New Interface on Lung Ventilation and Gas Distribution NCT04619641	University Magna Graecia	N/A
Completed	Concurrent Trigger Sensitivity Adjustment And Diaphragmatic Facilitation On Weaning From Mechanical Ventilatio NCT05387720	Cairo University	N/A
Completed	Lung Ultrasound Score and Weaning Outcome NCT05289960	Cairo University	N/A
Completed	REmimazolam Infusion in the Context of Hypnotic Shortage in the Critical Care Unit During the Pandemic of COVI NCT04611425	Nantes University Hospital	Phase 2
Completed	Pronostic Value of Type I ANTi-Interferon Antibodies in Patients With COVID-19 Acute Respiratory Failure NCT04733105	Assistance Publique - Hôpitaux de Paris	—
Completed	Revefenacin in Acute Respiratory Insufficiency in COPD NCT04315558	University of California, Los Angeles	Phase 2
Completed	Comparing Closed-loop FiO2 Controller With Conventional Control of FiO2 NCT04568642	Dr. Behcet Uz Children's Hospital	N/A
Completed	Survival Rates and Longterm Outcomes After COVID-19 NCT04601090	Oslo University Hospital	—
Completed	Expert Panel Statement for the Respiratory Management of COVID-19 Related Acute Respiratory Failure (C-ARF) NCT04534569	NMC Specialty Hospital	—
Completed	High Flow Nasal Cannula With Noninvasive Ventilation NCT04507425	University of Oklahoma	N/A
Unknown	Proportional Open Ventilation (POV) Device and Its Efficacy in Managing Acute Respiratory Failure in COVID-19 NCT04581161	Hill-Rom	N/A
Unknown	AKI Biomarkers in Coronavirus(COVID)-19 NCT04408248	Guy's and St Thomas' NHS Foundation Trust	—
Unknown	Helmet vs Face Mask in Patients With Acute Respiratory Distress Syndrome NCT04507802	Hamad Medical Corporation	N/A
Completed	Therapeutic Plasma Exchange Followed by Convalescent Plasma Transfusion in Severe and Critically Ill COVID-19 NCT04973488	Novacescu Alexandru	N/A
Withdrawn	Treatment of Lung Injury From COVID-19 Infection With Intravenous Sodium Nitrite NCT04401527	Hope Pharmaceuticals	Phase 2
Unknown	Low-field Thoracic Magnetic Stimulation Increases Peripheral Oxygen Saturation Levels in COVID-19 Patients NCT04895267	Elias Manjarrez	N/A
Completed	Early Prone Position on Coronavirus Disease 2019 Pneumonia NCT04427969	Sisli Hamidiye Etfal Training and Research Hospital	—
Terminated	Safety and Efficacy of Hyperbaric Oxygen for ARDS in Patients With COVID-19 NCT04327505	Karolinska Institutet	Phase 2 / Phase 3
Unknown	Impact of Respiratory Virus in Critically Ill Patients With Acute Respiratory Failure NCT04411368	Seoul St. Mary's Hospital	—
Terminated	ARrest RESpiraTory Failure From PNEUMONIA NCT04193878	Stanford University	Phase 3
Completed	Lung Ultrasound for COVID-19 Initial Triage and Monitoring NCT04474236	University Hospital, Toulouse	—
Completed	Noninvasive Respiratory Support in COVID-19 (CATCOVID-AIR) NCT04668196	Hospital Universitari Vall d'Hebron Research Institute	—
Unknown	Mavrilimumab in Severe COVID-19 Pneumonia and Hyper-inflammation (COMBAT-19) NCT04397497	Ospedale San Raffaele	Phase 2
Completed	Epidemiological and Demographic Data From 150 Patients Diagnosed With Coronavirus Disease 2019 Pneumonia NCT04430023	Sisli Hamidiye Etfal Training and Research Hospital	—
Completed	HFNC Treatment in COVID-19 Pneumonia NCT04424836	Sisli Hamidiye Etfal Training and Research Hospital	—
Unknown	Prone Positioning and High-flow Nasal Cannula in COVID-19 Induced ARDS NCT04391140	Hospital Universitari Vall d'Hebron Research Institute	N/A
Terminated	COVID Cohort Study NCT04393155	University of Vermont	—
Terminated	EASiVENT Study Comparing INTELLiVENT-ASV vs Non Automated Ventilation in Adult ICU Patients NCT04400643	Hamilton Medical AG	—
Completed	PRactice of VENTilation in COVID-19 Patients (PRoVENT-COVID) NCT04346342	Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)	—
Unknown	High Flow Nasal Cannula in Immunocompromised Patient With Acute Respiratory Failure NCT04293991	Ain Shams University	N/A
Recruiting	Inspiratory Effort in COVID-19 NCT04666246	University of Modena and Reggio Emilia	—
Completed	The Value of Rapid Shallow Breathing Indeks in Predicting Non-invasive Mechanical NCT04780503	Izmir Katip Celebi University	—
Terminated	Efficacy of Volume Ventilation in Patients With Acute Respiratory Failure at Risk of Obstructive Apneas or Obe NCT04131660	University Hospital, Rouen	N/A
Terminated	Positive and Quantitative Diagnosis of Pleural Effusions by Thoracic Ultrasonography in Patients With Acute Re NCT03846934	University Hospital, Limoges	—
Completed	Value of Diaphragmatic Motion Measurement at Ultrasonography to Predict Poor Prognosis in Emergency Department NCT04119505	University Hospital, Montpellier	—
Unknown	Outcomes of RV Dysfunction in Acute Exacerbation of Chronic Respiratory Diseases NCT04098094	Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil	—
Completed	HFNC During Bronchoscopy for Bronchoalveolar Lavage NCT04016480	University Magna Graecia	N/A
Completed	Novel Arm Restraint For Critically Ill Patients To Reduce Immobility, Sedation, Agitation and Cognitive Impair NCT04067622	University of Vermont	N/A
Unknown	Postoperative Respiratory Abnormalities NCT04079829	Efficacy Care R&D Ltd	—
Completed	METEOR Think NIV Pilot NCT04052542	University of Pittsburgh	N/A
Completed	Rounding Summaries for Families of Critically Ill Patients NCT03969810	Rush University Medical Center	N/A
Completed	Bougie or Stylet In Patients Undergoing Intubation Emergently (BOUGIE) NCT03928925	Vanderbilt University Medical Center	N/A
Completed	Patient-ventilator Synchronisation Study for Intensive Care Unit Patients NCT03787173	Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer	N/A
Unknown	Tissue Doppler Ultrasound During Spontaneous Breathing and Non-invasive Ventilation in the Post-extubation Per NCT03978221	Azienda Ospedaliero Universitaria Maggiore della Carita	N/A
Unknown	New Automated System for Continuous Real-time Monitoring of Transpulmonary Pressure NCT03945409	University of Milan	—
Completed	Study of Therapeutic Exercise in Acute Respiratory Failure to Improve Neuromuscular Disability Trial NCT03863470	University of Pennsylvania	N/A
Recruiting	The EXCEL Registry of Patients Requiring ECMO NCT03793257	Australian and New Zealand Intensive Care Research Centre	—
Completed	Preventing Cardiovascular Collapse With Administration of Fluid Resuscitation During Induction and Intubation NCT03787732	Vanderbilt University Medical Center	Phase 4
Completed	Observational Study of Expected ARF Recovery NCT03797313	Johns Hopkins University	—
Unknown	Effects of Secretion Removal in Ventilated Patients NCT03758547	IRCCS Azienda Ospedaliero-Universitaria di Bologna	N/A
Unknown	The Safety and Efficacy of FFR Protocol in NTUH System NCT03693157	National Taiwan University Hospital Hsin-Chu Branch	—
Completed	Psychological Trauma and Resilience After Critical Illness NCT05193123	Nantes University Hospital	—
Unknown	SuperNO2VA™ and General Anesthesia Postoperative Care NCT03969615	Vyaire Medical	N/A
Unknown	Noninvasive NAVA Versus Flow-triggered Noninvasive Pressure Support in Pediatric Respiratory Failure NCT03697863	Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico	—
Completed	Novel Arm Restraint in the Intensive Care Unit NCT03621475	University of Vermont	Phase 1
Unknown	Oxygenation Methods and Non-invasive Ventilation in Patients With Acute Respiratory Failure and a do Not Intub NCT03673631	Poitiers University Hospital	—
Unknown	High Flow Nasal Cannulas in Children NCT03689686	Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico	N/A
Completed	High-Flow Oxygen Therapy Following Tracheostomy NCT03721419	Barnes-Jewish Hospital	N/A
Completed	Drug Order for Rapid Sequence Intubation NCT03420950	Hennepin Healthcare Research Institute	N/A
Unknown	Efficacy of High Velocity Nasal Insufflation NCT03929055	University of Milan	N/A
Completed	Enhanced FoCUS in Patients With Shortness of Breath NCT05403619	Nantes University Hospital	—
Completed	Practice of Ventilation in Middle-Income Countries NCT03188770	Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)	—
Completed	Protocolized Post-Extubation Respiratory Support Study NCT03288311	Vanderbilt University Medical Center	N/A
Completed	Nutrition and Exercise in Critical Illness NCT03021902	Clinical Evaluation Research Unit at Kingston General Hospital	Phase 2
Withdrawn	Airway Inflammatory Response During Illness in Children With Respiratory Failure NCT02047877	University of North Carolina, Chapel Hill	—
Unknown	New Indirect Calorimetry Device for Energy Expenditure Measurement NCT02024958	University Hospital, Geneva	—
Completed	Mobile Critical Care Recovery Program for Acute Respiratory Failure Survivors NCT03053245	Indiana University	N/A
Completed	HFNC Alone or Associated With NIV for Immunocompromised Patients Admitted to ICU for Acute Respiratory Failure NCT02978300	Poitiers University Hospital	N/A
Completed	Preventing Cardiovascular collaPse With Administration of Fluid Resuscitation Before Endotracheal Intubation NCT03026777	Louisiana State University Health Sciences Center in New Orleans	Phase 4
Recruiting	China Extracorporeal Life Support Registry NCT04158479	Beijing Anzhen Hospital	—
Completed	Prophylactic Non-invasive Ventilation During Surgical Procedure in Rhythmology NCT02779998	University Hospital, Grenoble	N/A
Withdrawn	Fixed Low-dose Heparin Versus Standard Adjusted-dose Heparin Infusion in Adults Receiving Venovenous ECMO With NCT02966080	University of Arizona	N/A
Unknown	Initial Ventilation Strategy for Adult Immunocompromised Patients With Acute Respiratory Failure NCT02983851	Peking Union Medical College Hospital	N/A
Recruiting	Correlation Between Trans Esophageal Pressure and Non-invasive Respiratory Support Failure in Patients With Ac NCT03826797	University of Modena and Reggio Emilia	—
Unknown	Dexmedetomidine Versus Standard Clinical Practice During Non Invasive Mechanical Ventilation NCT02958150	Basque Health Service	Phase 4
Unknown	Diaphragmatic Ultrasound to Predict NIV Outcome in Patients With De-novo ARF NCT02976233	Fondazione Policlinico Universitario Agostino Gemelli IRCCS	—
Completed	Severe ARDS: Generating Evidence NCT03021824	Montefiore Medical Center	—
Completed	Bougie Use in Emergency Airway Management NCT02902146	Hennepin Healthcare Research Institute	N/A
Completed	Proportional Assist Ventilation for Minimizing the Duration of Mechanical Ventilation: The PROMIZING Study NCT02447692	London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's	N/A
Completed	Esophageal Manometry in Mechanically Ventilated Patients NCT02901158	Sahlgrenska University Hospital	—
Completed	Non-rebreather at Flush Rate Compared to Bag Valve Mask With Assist NCT02841592	Hennepin Healthcare Research Institute	N/A
Completed	A Pilot Study of Combined Cycle Ergometry and Amino Acids in the ICU NCT02822170	University of Vermont	N/A
Completed	A Randomised Controlled Trial of High-Flow Nasal Oxygen Versus Standard Oxygen Therapy in Critically Ill Immun NCT02739451	Assistance Publique - Hôpitaux de Paris	N/A
Completed	Prediction of Response to Recruitment Maneuvers in Patients With Acute Respiratory Failure NCT02907840	Università degli Studi di Ferrara	N/A
Completed	Comparison of Pre-oxygenation of NIV and HFNC Therapy for Intubation of ICU Patients With Acute Respiratory Fa NCT02668458	Poitiers University Hospital	N/A
Unknown	Weaning From Mechanical Ventilation Guided by Lung Ultrasound (Brazilian WEANLUS) NCT01966861	D'Or Institute for Research and Education	Phase 3
Completed	External Nasal Dilator and Oxygen Therapy in Respiratory Failure NCT02662387	Loma Linda University	N/A
Completed	Early Initiation of High-flow Nasal Cannula Oxygen Therapy in Patients With Acute Respiratory Failure in the E NCT03447457	Poitiers University Hospital	N/A
Unknown	Ultrasonography in the Emergency Department NCT02550184	Odense University Hospital	N/A
Completed	Imputation of PaO2 From SaO2 NCT02598492	Brigham and Women's Hospital	—
Completed	High Flow Nasal Cannula in the Emergency Department NCT03460119	Hospital Italiano de Buenos Aires	—
Completed	Diaphragm Ultrasound Vs Transpulmonary Pressure To Set PEEP in ARDS NCT02463773	University of Minnesota	N/A
Unknown	NAVA Unloading - Effects on Distribution of Ventilation NCT02711722	Karolinska University Hospital	N/A
Terminated	Impact of Early Enteral vs. Parenteral Nutrition on Risk of Gastric-Content Aspiration in Patients Requiring M NCT03411447	Centre Hospitalier Departemental Vendee	N/A
Terminated	Impact of Early Enteral vs. Parenteral Nutrition on Preservation of Gut Mucosa Integrity in Patients Requiring NCT03852940	Centre Hospitalier Departemental Vendee	N/A
Completed	Prognosis of Hematological Cancer Patient Underwent Mechanical Ventillation NCT02562105	Mansoura University	—
Completed	Better Arterial Cannulation Technique With Different Hemodynamics NCT02825615	Sultan Qaboos University	N/A
Completed	Pilot Study on Pairing Sedation Strategies and Weaning NCT02219659	MemorialCare Health System	N/A
Completed	High Flow Therapy for the Treatment of Respiratory Failure in the ED NCT02236559	Vapotherm, Inc.	N/A
Completed	Effects of Chest Wall Elastance on Pulmonary Mechanics of Acute Respiratory Failure (ARF) NCT02196870	Southeast University, China	—
Completed	Impact of Nasal High-flow vs Venturi Mask Oxygen Therapy on Weaning Outcome: a Multicenter, Randomized, Contro NCT02107183	Catholic University of the Sacred Heart	N/A
Unknown	NAVASET: Nava Level Titration Using Comfort Scales NCT02133443	University Hospital, Caen	N/A
Terminated	Treatment of Dyspnea in Do-not-intubate Patients NCT02114944	Tufts Medical Center	—
Completed	Ultrasound to Evaluate Failure of Liberation From Mechanical Ventilation NCT02723565	University Health Network, Toronto	—
Completed	Neurally Adjusted Ventilatory Assist (NAVA) Study in Adults With Acute Respiratory Failure NCT01730794	Massachusetts General Hospital	N/A
Completed	HFCWO on Pneumonic Respiratory Failure NCT02758106	Chung Shan Medical University	N/A
Completed	Pilot Study of High-flow Humidified Nasal Oxygen During Breaks From Noninvasive Ventilation NCT01925534	Tufts Medical Center	N/A
Completed	Pharmacokinetic Alterations During ECMO NCT01938079	Columbia University	N/A
Unknown	Comparison of Proportional Assist Ventilation And Neurally Adjusted Ventilator Assist NCT02056093	Pierre and Marie Curie University	N/A
Completed	Enteral Feeding Composition and Acute Respiratory Failure NCT02421614	Zahra Vahdat Shariatpanahi	Phase 2 / Phase 3
Terminated	Effect of Different Electric Muscle Stimulation in Patients With Severe Sepsis and Respiratory Failure NCT01895647	Mackay Memorial Hospital	N/A
Unknown	Effects of Different Crystalloid Solutions for Extra-corporeal Membrane Oxygenator (ECMO) Priming NCT02609360	Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico	N/A
Completed	Non Invasive Ventilation in Abdominal Postoperative Period NCT01971892	University Hospital, Montpellier	N/A
Terminated	SmartCare Driven Pressure Support-Non Invasive Ventilation Feasibility Study NCT01870089	University of Lausanne Hospitals	N/A
Completed	Feasibility of Upright Bed Position in ARDS Patients NCT02160561	Wake Forest University Health Sciences	N/A
Completed	Testing the Feasibility of Patient Controlled Sedation for Ventilated ICU Patients NCT01606852	University of Minnesota	Phase 1 / Phase 2
Unknown	Adjusted Ventilatory Assist (NAVA-NIV) in Infants: Short-term Physiological Study NCT02043990	Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico	N/A
Completed	Impact of Early Enteral vs. Parenteral Nutrition on Mortality in Patients Requiring Mechanical Ventilation and NCT01802099	Centre Hospitalier Departemental Vendee	N/A
Completed	New Setting of Neurally Adjusted Ventilatory Assist During Mask Noninvasive Ventilation NCT03041402	Southeast University, China	N/A
Completed	Oxygen Therapy During Acute Respiratory Failure in Immuno-compromised Patients NCT02424773	Assistance Publique - Hôpitaux de Paris	Phase 3
Completed	Muscle Ultrasound Signifies Condition Upgrade Leading Approach to Recovery NCT02014285	Wake Forest University Health Sciences	—
Unknown	Goal Directed Mechanical Ventilation Aimed at Optimal Lung Compliance NCT01668368	Wolfson Medical Center	N/A
Terminated	Variable Ventilation During Acute Respiratory Failure NCT01083277	Boston Medical Center	N/A
Unknown	Tracheostomy in ICU With a Double Lumen Endotracheal Tube NCT01691222	University of Genova	N/A
Unknown	Procedures and Follow-up of Percutaneous Tracheostomy in Intensive Care Unit NCT01792258	University of Genova	—
Unknown	Multicenter National Randomized Controlled Open Label Study Assessing Interest of Non Invasive Ventilation in NCT01626937	Centre Hospitalier d'Agen	N/A
Completed	"VARIABLE-PSV" Study NCT01580956	University Hospital, Montpellier	Phase 3
Unknown	NIV NAVA Versus NIV-PS in Pediatric Patients - Pilot Study NCT01873261	Hospital Universitario La Paz	—
Recruiting	Improving Non-invasive Ventilation NCT01571986	Università Vita-Salute San Raffaele	—
Unknown	Outcome of Patients Treated With ECLS NCT04405817	Nanjing Medical University	—
Completed	Study Comparing Two Ventilation Modes NAVA (Neurally Adjusted Ventilatory Assist) Mode and Spontaneous Breathi NCT02018666	Clinact	N/A
Completed	Observational Cohort Study of a National Extracorporeal Membrane Oxygenation Service for Adults With Respirato NCT03979222	University of Cambridge	—
Unknown	Prevention of Damage Induced by Facial Mask Ventilation NCT01351155	Ospedale San Donato	N/A
Completed	Cardinality Matching Study of Early v.s. Delayed VV ECMO in Severe Respiratory Failure NCT03981393	University of Cambridge	—
Unknown	Evaluation of Gas Exchange by the Measurement of Lung Diffusion for Carbon Monoxide During General Anaesthesia NCT01503879	San Gerardo Hospital	—
Completed	Effect of Thiamine on Oxygen Utilization (VO2) in Critical Illness NCT01462279	Beth Israel Deaconess Medical Center	N/A
Terminated	Trial of Supplemental Parenteral Nutrition in Under and Over Weight Critically Ill Patients (TOP-UP) NCT01206166	Clinical Evaluation Research Unit at Kingston General Hospital	Phase 3
Completed	Epidemiology of Respiratory Insufficiency in Critical Care NCT01268410	Hospital Sirio-Libanes	—
Completed	Clinical Effect of the Association of Noninvasive Ventilation and High Flow Nasal Oxygen Therapy in Resuscitat NCT01320384	Poitiers University Hospital	Phase 2 / Phase 3
Completed	The Use of Palliative Non Invasive Ventilation in Acute Respiratory Failure. OVNI Study. NCT01449331	Assistance Publique - Hôpitaux de Paris	—
Terminated	Evaluation of Oxygen Therapy Delivery Systems in Hypoxemic Acute Respiratory Failure NCT01243918	Nantes University Hospital	N/A
Unknown	FRC Guided Therapy in Acute Respiratory Failure NCT01280019	University of Luebeck	Phase 4
Completed	Prevention Inhalation of Bacterial by Using Endotracheal Tube Balloon Polyvinyl Chloride or Polyurethane NCT01114022	Assistance Publique - Hôpitaux de Paris	N/A
Completed	Third International Study on Mechanical Ventilation NCT01093482	Hospital Universitario Getafe	—
Completed	Noninvasive Positive Airway Pressure Ventilation and Risk of Facial Pressure Ulcers NCT01828151	Ospedale S. Giovanni Bosco	—
Completed	Standardized Rehabilitation for Intensive Care Unit (ICU) Patients With Acute Respiratory Failure NCT00976833	Wake Forest University	N/A
Completed	Treatment of Critical Illness Polyneuromyopathy NCT01058421	University of Colorado, Denver	N/A
Completed	Evaluation of Different Continuous Positive Airway Pressure (CPAP) Systems in Patients With Acute Respiratory NCT00876473	Policlinico Hospital	—
Completed	Efficacy and Safety of Dexmedetomidine During Non-Invasive Positive Pressure Ventilation NCT00871624	Tufts Medical Center	Phase 2
Completed	Predicting Success of HFNC: The Utility of the ROX Index NCT02834325	Hospital Universitari Vall d'Hebron Research Institute	—
Completed	Noninvasive Continuous Positive Airway Pressure (NCPAP) in Children NCT01242150	Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico	Phase 3
Completed	Outcomes of Mechanically Ventilated Patients With Low Serum Testosterone NCT00797433	The University of Texas Health Science Center, Houston	—
Completed	Clinical Evaluation of Swallowing Disorders as a Predictor of Extubation Failure NCT00780078	Assistance Publique - Hôpitaux de Paris	—
Terminated	Early Rehabilitation of COPD Patients in ICU NCT00628992	University Hospital, Strasbourg, France	N/A
Completed	Effect Of Acute Inflammatory Mediators On Functional Limitations In Patients With Acute Respiratory Failure NCT01707303	Wake Forest University	N/A
Completed	Protocol Chronic Obstructive Pulmonary Disease NCT00404430	University Hospital, Grenoble	—
Completed	Réa-MiniMax: Severe Acute Respiratory Failure in Hematology and Cancer Patients Without Bronchoalveolar Lavage NCT00248443	Assistance Publique - Hôpitaux de Paris	Phase 3
Completed	Early Mechanical Ventilation for Guillain Barré Syndrome NCT00167622	University of Versailles	Phase 2
Unknown	Effect of Increased Muscular Work During Different Weaning Strategies in Critically Ill Patients NCT00538746	Università degli Studi dell'Insubria	N/A
Completed	Continuous Positive Airway Pressure and Oxygen Concentration on Measurement of Rapid Shallow Breathing Index NCT00632320	Taipei Veterans General Hospital, Taiwan	—
Completed	Effects of PEEP and FIO2 in ALI and ARDS NCT00435110	Instituto Canario de Investigacion Biomedica	—
Terminated	Non-Invasive Mechanical Ventilation in Elderly Patients NCT00600639	IRCCS Azienda Ospedaliero-Universitaria di Bologna	Phase 4
Completed	Timing of Target Enteral Feeding in the Mechanically Ventilated Patient NCT00252616	Vanderbilt University	Phase 2 / Phase 3
Completed	Non-Positive Pressure Ventilation in Hypoxemic Patients NCT00925860	Hospital Provincial de Castellon	Phase 4
Completed	Heparin Binding Protein in Patients With Acute Respiratory Failure Treated With GCSF (Filgrastim) NCT01713309	Helsinki University Central Hospital	Phase 2 / Phase 3
Completed	Extracorporeal Support for Respiratory Insufficiency (ECMO) NCT00000562	National Heart, Lung, and Blood Institute (NHLBI)	Phase 3