| Not Yet Recruiting | NHLBI-Emory Advanced Cardiac CT Reconstruction Structural Heart Disease | — | 2026-04-22 |
| Not Yet Recruiting | Syk Inhibition in MItigating Lung Allograft Rejection (SIMILAR): A Trial to Evaluate the Safety and Tolerabili Lung Transplantation | Phase 1 | 2026-04-22 |
| Not Yet Recruiting | GRAfT 2.0. A Multimodal Prospective Approach to Define the Mechanisms and Clinical Features of Acute and Chron Lung Transplant, End Stage Lung Disease, Rejection | — | 2026-04-22 |
| Enrolling By Invitation | VINTAGE (Ventricular Intramyocardial Navigation for Tachycardia Ablation Guided by Electrograms) Using Commerc Ventricular Arrhythmia | N/A | 2026-04-22 |
| Enrolling By Invitation | Multi-Scale Analysis of Phenotypes in Heart Failure (MAP-HEART) Heart Failure | — | 2026-04-22 |
| Enrolling By Invitation | EDEN Intracardiac Electrogram Recording and Classifying System Ventricular Arrhythmia | N/A | 2026-04-22 |
| Recruiting | Platelet Volunteers, Longitudinal and Multi-omic Study Thrombosis | — | 2026-03-26 |
| Recruiting | Immune Profiling of CLL/SLL Treated With First-Line Pirtobrutinib Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL) | EARLY_Phase 1 | 2026-03-11 |
| Recruiting | Baricitinib in the Treatment of Kohlmeier-Degos Disease in Patients With Neurological Involvement Kohlmeier-Degos Disease, Malignant Atrophic Papulosis, Degos Disease | Phase 2 | 2026-02-18 |
| Withdrawn | Extension Study (Extended Access) of Syk-inhibition Using Fostamatinib to Treat Posttransplant Immune-mediated Immune Mediated Anemia, Immune Mediated Thrombocytopenia, Chronic GVHD | Phase 2 | 2025-11-07 |
| Enrolling By Invitation | Molecular and Clinical Analysis of Bone Marrow Failure: A Secondary Research Study Bone Marrow Failure Disorders, VEXAS Syndrome, Hemoglobinurea, Paroxysmal | — | 2025-09-09 |
| Suspended | NHLBI and Cook Trans-Atrial Intra-Pericardial Tricuspid Annuloplasty (TRAIPTA) Early Feasibility Study Tricuspid Valve Insufficiency | N/A | 2025-08-19 |
| Active Not Recruiting | Epcoritamab in Chronic Lymphocytic Leukemia and Richter Syndrome Leukemia, Chronic Lymphocytic, Richter Syndrome | Phase 1 | 2025-07-18 |
| Recruiting | Natural History of Uncommon Dyslipidemias, Rare Lipid Disorders and Unusual Atherosclerotic Conditions Dyslipidemia, Atherosclerosis | — | 2025-01-15 |
| Terminated | NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Early Feasibility Study Hypertrophic Cardiomyopathy, Left Ventricular Septal Hypertrophy, Mitral Valve Disease | N/A | 2024-12-18 |
| Recruiting | Study to Evaluate the Safety and Tolerability of Escalating Doses of Fostamatinib in Subjects With Stable Sick Sickle Cell Disease, Hb-SS Disease, Hemoglobin S | Phase 1 | 2024-12-18 |
| Recruiting | OurSleepKit To Support CPAP Adherence Obstructive Sleep Apnea, CPAP Treatment, Treatment Adherence | N/A | 2024-12-03 |
| Recruiting | Thrombosis and Inflammation in Vessels Initiative (TIVI) Cardiovascular Diseases, Vascular Diseases | — | 2024-11-22 |
| Recruiting | Human Milk Oligosaccharide-Based Synbiotic Supplement for Intestinal Microbiota Dysbiosis Healthy Volunteers | EARLY_Phase 1 | 2024-11-15 |
| Recruiting | Determination of Red Cell Survival in Sickle Cell Disease and Other Hemoglobinopathies Using Biotin Labeling Sickle Cell Disease, Thalassemia, Hemoglobinopathy | EARLY_Phase 1 | 2024-05-17 |
| Active Not Recruiting | Investigating the Mechanistic Effects of Mitapivat in Subjects With Sickle Cell Disease Sickle Cell Anemia, Sickle Cell Thalassemia, Sickle Cell Pain | — | 2024-05-09 |
| Recruiting | Technical Development of Cardiovascular Magnetic Resonance Imaging Cardiovascular Disease | — | 2024-04-08 |
| Recruiting | Early Detection of Infectious and Noninfectious Lung Diseases Following Allogeneic Hematopoietic Stem Cell Tra Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) | — | 2024-04-08 |
| Recruiting | Double-blind Placebo Controlled Study to Evaluate the Effect of NAD+ Boosting With Nicotinamide Riboside on Im Systemic Lupus Erythematosus (Sle) | Phase 1 / Phase 2 | 2024-03-13 |
| Recruiting | JAK1/2 Inhibitor Ruxolitinib for Relapsed/Refractory Immune Bone Marrow Failure Severe Aplastic Anemia, Single Lineage Cytopenias, T-LGL, Hypoplastic MDS | Phase 1 / Phase 2 | 2024-02-20 |
| Recruiting | Healing Within: Mindfulness Smoking Cessation Intervention Smoking Cessation | N/A | 2024-01-25 |
| Active Not Recruiting | Non-myeloablative Haploidentical HCT Study for Patients With Sickle Cell Disease, Including Compromised Organ Sickle Cell Disease | Phase 1 / Phase 2 | 2023-12-28 |
| Recruiting | Study of Intravenous ZMA001 in Healthy Subjects Pulmonary Arterial Hypertension PAH | Phase 1 | 2023-11-27 |
| Completed | JAK/STAT Inhibition in CNS Kohlmeier-Degos Disease Kohlmeier Degos Disease With Neurologic Involvement, Kohlmeier-Degos Disease | Phase 1 / Phase 2 | 2023-09-28 |
| Completed | Study of the Selective GlyT1 Inhibitor Bitopertin for Steroid-Refractory Diamond-Blackfan Anemia Steroid-refractory Diamond-Blackfan Anemia (DBA) | Phase 1 / Phase 2 | 2023-07-25 |
| Terminated | Using Fostamatinib to Treat Post-Hematopoietic Stem Cell Transplant Immune-mediated Cytopenias Immune Mediated Anemia, Immune Mediated Thrombocytopenia, Chronic GVHD | Phase 2 | 2023-03-10 |
| Recruiting | Observational Study of Cardiac Arrhythmias During Treatment With BTK Inhibitors or Venetoclax Chronic Lymphocytic Leukemia (CLL), Waldenstr(SqrRoot)(Delta)m s Macroglobulinemia, Mantle Cell Lymphoma | — | 2023-03-01 |
| Completed | NHLBI Transmural Electrosurgery LeafLet Traversal And Laceration Evaluation (TELLTALE) BASILICA-TAVR Trial Valvular Heart Disease, Aortic Valve Failure | N/A | 2023-02-21 |
| Withdrawn | Structural Heart and Valve Network PROSPECTIVE Registry Mitral Valve Regurgitation, Heart Failure, Heart Valve Disease | — | 2023-01-10 |
| Completed | Exploring Near Infrared Spectroscopy (NIRS) Technologies for Assessment of Muscle Physiology, Tissue Oxygenati SCD | — | 2022-11-28 |
| Recruiting | Vaccine Responses in Patients With B Cell Malignancies Lymphoma | Phase 4 | 2022-09-14 |
| Recruiting | Controls and Healthy Vasculature Initiative Vascular And Immunologic Diseases, Healthy Volunteers | — | 2022-07-01 |
| Withdrawn | The Effect of Inflammation in Heart Failure Myocardial Dysfunction, Heart Failure, Inflammation | Phase 2 | 2022-06-23 |
| Active Not Recruiting | Addition of JSP191 (C-kit Antibody) to Nonmyeloablative Hematopoietic Cell Transplantation for Sickle Cell Dis Sickle Cell Anemia, Beta Thalassemia | Phase 1 / Phase 2 | 2022-05-12 |
| Completed | Characterization of Tissue-Specific Immune Responses to Bronchoscopic Instillation of Mycobacterial Antigens I Healthy, Latent Tuberculosis Infection (LTBI) | EARLY_Phase 1 | 2022-05-03 |
| Recruiting | Natural History Study of CADASIL Cardiovascular Disease, Arterial Stiffness, Germline Mutation in the NOTCH 3 Gene | — | 2022-04-18 |
| Recruiting | Observational Study to Deeply Phenotype Major Organs in Sickle Cell Disease After Curative Therapies Mortality in Sickle Cell, Sickle Cell Cardiopulmonary Complications, Sickle Cell Organ Damage | — | 2022-03-24 |
| Recruiting | Natural History of Acquired and Inherited Bone Marrow Failure Syndromes Severe Aplastic Anemia, Telomere Biology Disorders, Inherited Bone Marrow Failure Syndromes | — | 2021-10-25 |
| Recruiting | Geospatial Analysis of Neighborhood Environmental Stress in Relation to Biological Markers of Cardiovascular H Cardiovascular (CV) Risk | — | 2021-10-20 |
| Recruiting | Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Fx-5A in Healthy Volunteers Cardiovascular Disease | Phase 1 | 2021-09-29 |
| Completed | Anti-Inflammatory Effects of Time-Restricted Feeding Psoriasis, Systemic Inflammation | — | 2021-06-09 |
| Terminated | Effect of Chronic Inflammation on Myocardial Perfusion and Function Psoriasis | — | 2021-06-07 |
| Completed | Gene First Approach to Connective Tissue Disease Abnormal Elastogenesis, Vascular Diseases, Connective Tissue Diseases | — | 2021-04-22 |
| Completed | Red Cell Half Life Determination in Patients With and Without Sickle Cell Disease Sickle Cell Disease, Sickle Cell Anemia | EARLY_Phase 1 | 2021-04-19 |
| Completed | Genomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African Americans Study ( Cardiovascular Disease | N/A | 2021-01-22 |
| Active Not Recruiting | Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Long-term Mitapivat Dosing in Subjects With St Sickle Cell Disease, Hemolytic Anemia | Phase 1 / Phase 2 | 2020-12-09 |
| Completed | Treatment of Refractory Diamond-Blackfan Anemia With Eltrombopag Anemia, Diamond-Blackfan | Phase 1 / Phase 2 | 2020-12-01 |
| Completed | Fixed Dose Flavonoid Isoquercetin on Thrombo-Inflammatory Biomarkers in Subjects With Stable Sickle Cell Disea Sickle Cell Disease | Phase 2 | 2020-11-02 |
| Completed | Patients' Long-Term Survival of Obstructive Hypertrophic Cardiomyopathy (HCM) Cardiomyopathy, Obstructive Hypertrophic Cardiomyopathy | — | 2020-10-20 |
| Completed | Fostamatinib for Hospitalized Adults With COVID-19 Coronavirus Disease 2019 | Phase 2 | 2020-10-08 |
| Completed | COV2Base-A Rare Disease by COVID Study Chronic Health Conditions, Older Age is Associated With Increased Pathogenicity | — | 2020-10-04 |
| Completed | Venous Thrombosis Biomarkers in Sickle Cell Disease and Sickle Cell Trait Sickle Cell Disease, Venous Thrombosis, Sickle Cell Trait | — | 2020-09-01 |
| Completed | Pilot Study to Evaluate the Effect of Nicotinamide Riboside on Immune Activation in Psoriasis Psoriasis, Atherosclerotic Cardiovascular Disease, Obesity | N/A | 2020-08-26 |
| Terminated | Duvelisib for Ibrutinib-Resistant Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Small Lymphocytic Leukemia (SLL), Chronic Lymphocytic Leukemia (CLL) | Phase 2 | 2020-07-31 |
| Enrolling By Invitation | Data Collection of Standard Care and Evaluation of NHLBI Patients and Donors Wide Spectrum of Diseases, Hematologic Diseases | — | 2020-06-16 |
| Completed | Retrospective Study of Patients With Severe Aplastic Anemia Who Relapsed After Immunosuppressive Therapy Severe Aplastic Anemia | — | 2020-06-15 |
| Completed | Retrospective Study of Patients With Severe Aplastic Anemia Who Developed High Risk Clonal Evolution With Chro Severe Aplastic Anemia | — | 2020-06-15 |
| Recruiting | Early Initiation of Oral Therapy With Cyclosporine and Eltrombopag for Treatment Naive Severe Aplastic Anemia Severe Aplastic Anemia | Phase 2 | 2020-05-07 |
| Recruiting | CHIP/CCUS Natural History Protocol Clonal Hematopoiesis of Indeterminate Potential, Clonal Cytopenia of Undetermined Significance | — | 2020-03-03 |
| Recruiting | Repeat Peripheral Blood Stem Cell Transplantation for Patients With Sickle Cell Disease and Falling Donor Myel Myeloid Chimerism | Phase 1 / Phase 2 | 2019-10-24 |
| Recruiting | Early Clonal Dynamics During Venetoclax Treatment for Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL Chronic Lymphocytic Leukemia | Phase 2 | 2019-06-26 |
| Completed | Best Noninvasive Predictor of Renal Function in Assessing Adult Sickle Nephropathy Sickle Cell Disease | — | 2019-05-24 |
| Active Not Recruiting | NHLBI DIR Transcatheter Mitral Cerclage Annuloplasty Early Feasibility Study Functional Mitral Regurgitation | N/A | 2019-05-07 |
| Completed | Nicotinamide Riboside on Mitochondrial Function in Li-Fraumeni Syndrome Cancer, Skin Fibroblasts, Muscle Weakness | Phase 1 / Phase 2 | 2019-03-25 |
| Recruiting | Haplo-identical Transplantation for Severe Aplastic Anemia, Hypo-plastic MDS and PNH Using Peripheral Blood St Severe Aplastic Anemia (SAA), Hypo-Plastic Myelodysplastic Syndrome (MDS), Paroxysmal Nocturnal Hemoglobinuria (PNH) | Phase 2 | 2019-02-19 |
| Completed | HEPLISAV-B Hepatitis B Vaccine in Chronic Lymphocytic Leukemia (CLL) and CLL Treated With Bruton's-Tyrosine Ki Hepatitis, Safety and Tolerability | Phase 2 | 2018-12-07 |
| Completed | Response to the SHINGRIX Varicella Zoster Virus (VZV) Vaccine in Chronic Lymphocytic Leukemia (CLL) and CLL Tr Safety and Tolerability, Compare SHINGRIX Vaccine Response Rates, Chronic Lymphocytic Leukemia (CLL) | Phase 2 | 2018-12-07 |
| Active Not Recruiting | Eltrombopag for People With Fanconi Anemia Fanconi Anemia | Phase 2 | 2018-11-02 |
| Recruiting | Genotype -Phenotype Correlation of PKLR Variants With Pyruvate Kinase, 2,3-Diphosphglycerate and Adenosine Tri Sickle Cell, PKLR Variants, Adenosine Triphosphate Activities | — | 2018-10-11 |
| Terminated | The Effect of Nicotinamide Riboside on Skeletal Muscle Function in Heart Failure Subjects Heart Failure | Phase 2 | 2018-09-27 |
| Recruiting | Dietary Omega-7 Palmitoleic Acid-Rich Oil on Lipoprotein Metabolism and Satiety in Adults Cardiovascular Disease | Phase 2 | 2018-07-31 |
| Recruiting | Vascular Disease Discovery Protocol Vascular Dysfunction, Genetic Mutations, Genetic Predisposition | — | 2018-07-30 |
| Active Not Recruiting | HERV-E TCR Transduced Autologous T Cells in People With Metastatic Clear Cell Renal Cell Carcinoma Kidney Cancer | Phase 1 | 2018-07-20 |
| Recruiting | Technical and Translational Development of Cardiovascular Magnetic Resonance (CMR) Imaging Normal and Abnormal Cardiovascular Physiology | — | 2018-07-12 |
| Recruiting | Tailoring Mobile Health Technology to Reduce Obesity and Improve Cardiovascular Health in Resource-Limited Nei Obesity | N/A | 2018-06-21 |
| Completed | Phosphodiesterase Type-5 Inhibitor Therapy in Sickle Cell People With Pulmonary Hypertension Pulmonary Hypertension, Sickle Cell Disease | — | 2018-06-20 |
| Completed | Effectiveness of the Hepatitis B Vaccine Post-Hematopoietic Stem Cell Transplant Hepatitis B | — | 2018-04-13 |
| Completed | Early Diagnosis of Sickle Acute Chest Syndrome Using a Combination of Plasma Bimarkers and Chest Imaging Sickle Cell Disease (SCD) | — | 2018-02-27 |
| Completed | Bioprosthetic or Native Aortic Scallop Intentional Laceration to Prevent Iatrogenic Coronary Artery Obstructio Native and Valve in Valve Aortic Valve Failure | N/A | 2018-02-14 |
| Recruiting | Low-Dose Danazol for the Treatment of Telomere Related Diseases Telomere Disease | Phase 2 | 2018-02-08 |
| Terminated | Transmural Systems Transcaval Closure Device for Transcaval Access Ports During Transcatheter Aortic Valve Rep Aortic Stenosis | N/A | 2018-02-07 |
| Recruiting | Technical Development of Cardiovascular Magnetic Resonance Imaging (CMR) Using a Low Specific Absorption Rate CAD | N/A | 2018-01-05 |
| Completed | Discovery of Sirolimus Sensitive Biomarkers in Blood Lymphangioleiomyomatosis | Phase 2 | 2017-12-04 |
| Completed | dbGaP Protocol: The Pediatric Cardiac Genetics Consortium (PCGC) Congenital Heart Disease | — | 2017-10-20 |
| Completed | Prospective Multicenter Registry On Radiation Dose Estimates Of Cardiac CT Angiography in Daily Practice in 20 Coronary Artery Disease, Coronary Disease, Myocardial Ischemia | — | 2017-10-03 |
| Completed | Ibrutinib, Fludarabine, and Pembrolizumab in High-Risk or Relapsed/Refractory Chronic Lymphocytic Leukemia/Sma B-Cell Chronic Lymphocytic Leukemia, B-Lymphocytic Leukemia, Chronic, Chronic Lymphocytic Leukemia | Phase 2 | 2017-09-22 |
| Suspended | Heart Catheterization Using Magnetic Resonance Imaging (MRI) Fluoroscopy and Passive Guidewires Pulmonary Artery Hypertension, Congenital Heart Disease, Structural Heart Disease | N/A | 2017-08-02 |
| Completed | Peripheral Blood Stem Cell Collection for Sickle Cell Disease (SCD) Patients Sickle Cell Disease | Phase 1 | 2017-07-25 |
| Completed | Extracellular RNAs in Relation to Cardiometabolic Risk Subclinical Atherosclerotic Cardiovascular Disease, Blood Pressure, Obesity | — | 2017-07-17 |
| Completed | RNA Sequencing in the Framingham Heart Study Third Generation Cohort Exam 2 Cardiovascular Disease, Hypertension | — | 2017-07-14 |
| Completed | NHLBI DIR LAMPOON Study: Intentional Laceration of the Anterior Mitral Leaflet to Prevent Left Ventricular Out Mitral Valve Failure | N/A | 2017-06-20 |
| Completed | Effect of Fish Oil Enriched In Omega-11 Fatty Acid On Lipoprotein Metabolism In Adults Lipoprotein Metabolism, PCSK9, Proteomics | Phase 2 | 2017-06-15 |
| Recruiting | Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS Using CordIn(TM Severe Aplastic Anemia, Hypo-Plastic MDS, Myelodysplastic Syndrome (MDS) | Phase 1 / Phase 2 | 2017-06-13 |
| Active Not Recruiting | Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Si Sickle Cell Disease | Phase 1 / Phase 2 | 2017-04-06 |
| Completed | Pathophysiology of Acute Pain in Patients With Sickle Cell Disease Sickle Cell Disease | — | 2017-03-13 |
| Completed | WS-SAVE Study (Williams Syndrome Skin and Vessel Elasticity Study) Williams Syndrome, Cardiovascular Disease, Multisystem Developmental Disorder | — | 2017-03-03 |
| Completed | Lung Tissue Research Consortium Chronic Obstructive Pulmonary Disease, Interstitial Lung Disease | — | 2017-02-23 |
| Active Not Recruiting | Sirolimus (Rapamune ) for Relapse Prevention in People With Severe Aplastic Anemia Responsive to Immunosuppres Severe Aplastic Anemia | Phase 2 | 2016-12-19 |
| Completed | Pembrolizumab and Decitabine for Refractory or Relapsed Acute Myeloid Leukemia Relapsed Acute Myeloid Leukemia | Phase 1 / Phase 2 | 2016-12-16 |
| Completed | Impact of Elastin Mediated Vascular Stiffness on End Organs Williams Syndrome, Supravalvular Aortic Stenosis, Cardiovascular Disease | — | 2016-12-02 |
| Completed | CADASIL Disease Discovery Germline Mutation in the NOTCH 3 Gene, Cardiovascular Disease, Arterial Stiffness | — | 2016-10-18 |
| Completed | Dendritic Cell/Myeloma Fusion Vaccine for Multiple Myeloma (BMT CTN 1401) Multiple Myeloma | Phase 2 | 2016-07-01 |
| Completed | Study to Evaluate the Effect of Nicotinamide Riboside on Immunity Atherosclerosis, Diabetes, Coronary Artery Disease | N/A | 2016-06-23 |
| Completed | The National Myelodysplastic Syndromes (MDS) Study Myelodysplastic Syndromes (MDS) | — | 2016-06-13 |
| Recruiting | Williams Syndrome (WS) and Supravalvar Aortic Stenosis (SVAS) DNA and Tissue Bank Williams Syndrome, Supravalvular Aortic Stenosis, Cardiovascular Disease | — | 2016-05-11 |
| Completed | Effect of Fasting and Refeeding on T-cell Fate Asthma, Inflammation | — | 2016-04-18 |
| Terminated | CT COMPARE: CT Coronary Angiography to Measure Plaque Reduction Cardiovascular Disease | Phase 4 | 2016-04-11 |
| Active Not Recruiting | A Phase II Study Using Ibrutinib and Short-Course Fludarabine in Treatment-Naive CLL Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma | Phase 2 | 2015-12-09 |
| Completed | High Image Matrix CT Reconstruction Healthy Subjects, Pulmonary-Related Conditions, Cardiac-Related Conditions | — | 2015-11-09 |
| Completed | Comparison of EPA and DHA-Rich Fish Oils on Lipoprotein Metabolism In Adults Lipoprotein Metabolism, PCSK9, Proteomics | Phase 2 | 2015-10-30 |
| Recruiting | Human Biospecimen Procurement Protocol: Biorepository to Support Translational Research to Identify Disease Me Undiagnosed Diseases, Cardiovascular Disease | — | 2015-09-17 |
| Completed | Behavioral Economics Framingham Incentive Trial (BE FIT) Physical Activity | N/A | 2015-09-01 |
| Completed | Effect of Fasting on the Asthma Inflammasome Asthma | — | 2015-08-26 |
| Completed | Biomarkers for Personalized Early Assessment of Response During Salvage Chemotherapy in People With Relapsed o Acute Myeloid Leukemia | — | 2015-08-18 |
| Completed | Allogeneic Hematopoietic Stem Cell Transplantation With Ixazomib for High Risk Multiple Myeloma (BMT CTN 1302) Multiple Myeloma | Phase 2 | 2015-08-01 |
| Completed | Calcineurin Inhibitor-Free Interventions BMT CTN 1301 for Prevention of Graft-versus-Host Disease (BMT CTN 130 Acute Leukemia, Myelodysplasia | Phase 3 | 2015-08-01 |
| Completed | Hereditary Parkinson s Disease Natural History Protocol Parkinson Disease 6, Early-Onset, Parkinson Disease (Autosomal Recessive, Early Onset) 7, Human, Parkinson Disease Autosomal Recessive, Early Onset | — | 2015-07-08 |
| Recruiting | Genome Transplant Dynamics Thoracic Organ Transplantation | — | 2015-06-25 |
| Completed | dbGaP Protocol: Genetic Variants Associated With Pentalogy of Cantrell Pentalogy of Cantrell | — | 2015-04-25 |
| Completed | Effects of Niacin Therapy on Lipoprotein Composition and Function Cardiovascular Disease | N/A | 2015-03-25 |
| Terminated | Characterization of the Pathogenesis of Primary and Secondary Lymphatic Disorders Lymphangiomatosis, Lymphedema, Lymphangiectasia | — | 2015-03-23 |
| Completed | Continued, Long-Term Follow-Up and Lenalidomide Maintenance Therapy for Patients on BMT CTN 0702 Protocol (BMT Multiple Myeloma | Phase 3 | 2015-03-01 |
| Terminated | Early Treatment of Acute Graft Versus Host Disease With Bone Marrow-Derived Mesenchymal Stem Cells and Cortico Graft-Versus-Host Disease | Phase 1 / Phase 2 | 2015-02-23 |
| Completed | Characterization of Apolipoprotein A-I Pathways in Idiopathic Pulmonary Fibrosis Idiopathic Pulmonary Fibrosis | — | 2015-01-28 |
| Completed | Prospective International Study of Coronary Subtraction Using 320 Detector Row CT (CorSub) Coronary Artery Disease | — | 2015-01-06 |
| Completed | Genes Involved in Lipid Disorders Lipid Disorders | — | 2014-11-26 |
| Completed | Complement Inhibition Using Eculizumab to Overcome Platelet Transfusion Refractoriness in Patients With Severe Thrombocytopenia, Alloimmune Platelet Refractoriness | Phase 2 | 2014-11-21 |
| Completed | Minority Health Genomics and Translational Research Bio-Repository Database (MH-GRID)-2.0 Hypertension | — | 2014-11-11 |
| Completed | Transcaval Access for Transcatheter Aortic Valve Replacement in People With No Good Options for Aortic Access Aortic Valve Stenosis | Phase 1 | 2014-10-30 |
| Completed | Clinical Outcomes and Molecular Phenotypes in Smokers With Parenchymal Lung Disease Pulmonary Fibrosis, Lung Disease | — | 2014-10-14 |
| Recruiting | Prospective Evaluation of Next Generation CT Reconstruction (NextGenIR) Healthy Subjects | — | 2014-09-08 |
| Terminated | Phase I/II Trial of Early Infusion of Rapidly-generated Multivirus Specific T Cells (MVST) to Prevent Post Tra Chronic Lymphocytic Leukemia, CML (Chronic Myelogenous Leukemia), MDS (Myelodysplastic Syndrome) | Phase 1 | 2014-09-03 |
| Completed | Ultra-Low Dose IL-2 Therapy as GVHD Prophylaxis in Haploidentical Allogeneic Stem Cell Transplantation Acute Lymphoblastic Leukemia (ALL), Acute Myelogenous Leukemia (AML), Chronic Lymphocytic Leukemia (CLL) | Phase 1 | 2014-08-26 |
| Completed | Assessment of Algorithm-Based Hydroxyurea Dosing on Fetal Hemoglobin Response, Acute Complications, and Organ Sickle Cell Disease | Phase 1 / Phase 2 | 2014-08-23 |
| Completed | Novel Approaches for Graft-versus-Host Disease Prevention Compared to Contemporary Controls (BMT CTN 1203) Acute Leukemia, Chronic Myelogenous Leukemia, Myelodysplasia | Phase 2 | 2014-08-01 |
| Completed | Genomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African-Americans Study ( Hypertension | — | 2014-07-23 |
| Completed | Effect of Fasting on the NLRP3 Inflammasome Cardiovascular Disease, Inflammatory Disease | — | 2014-04-21 |
| Active Not Recruiting | Nonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disea Sickle Cell Disease, Thalassemia, Stem Cell Transplantation | Phase 2 | 2014-04-21 |
| Recruiting | Heart Health Study in Washington D.C. to Develop a Community-Based Behavioral Weight Loss Intervention Cardiovascular Disease, Obesity | — | 2014-02-08 |
| Completed | Links Between Inflammation and Cardiometabolic Diseases Diabetes Mellitus, Cardiovascular Disease, Healthy Volunteer | — | 2013-12-02 |
| Withdrawn | Hydroxyurea in Pulmonary Arterial Hypertension Pulmonary Hypertension | EARLY_Phase 1 | 2013-09-06 |
| Completed | Extended Dosing With Eltrombopag for Severe Aplastic Anemia Severe Aplastic Anemia (SAA) | Phase 2 | 2013-06-28 |
| Withdrawn | Use of Cardiac-MRI to Predict Results for People With Severe Aortic Stenosis Aortic Valve Stenosis | — | 2013-06-27 |
| Recruiting | Nebulized or Inhaled Albuterol for Lymphangioleiomyomatosis Lymphangioleiomyomatosis | Phase 1 / Phase 2 | 2013-06-10 |
| Completed | Preventing Stem Cell Transplant Complications With a Blood Separator Machine MDS (Myelodysplastic Syndrome), Myeloproliferative Disorder, Lymphoma, Non-Hodgkin | Phase 1 / Phase 2 | 2013-05-29 |
| Completed | Effects of Roflumilast on Insulin and Blood Sugar Levels in Prediabetic Overweight and Obese Individuals Obesity | Phase 1 / Phase 2 | 2013-05-22 |
| Completed | Pilot Study of Strength Testing in Overweight Women With or Without Insulin Resistance Obesity | — | 2013-05-06 |
| Completed | Medical Arm of the Interagency Registry for Mechanically Assisted Circulatory Support Heart Failure, Systolic Heart Failure | — | 2013-04-01 |
| Completed | Longitudinal Observational Study of Severe Asthma Asthma | — | 2013-03-01 |
| Completed | Intravenous ACP-501 for Familial LCAT Deficiency (rhLCAT) Familial LCAT Deficiency | — | 2013-01-24 |
| Completed | The Psoriasis, Atherosclerosis, and Cardiometabolic Disease Initiative (PACI) Metabolic Disease, Cardiovascular Disease, Inflammation | — | 2013-01-22 |
| Terminated | Myocardial Perfusion and Scarring in Congenital Heart Disease Congenital Heart Disease | — | 2012-10-24 |
| Completed | Pediatric Hydroxyurea Phase III Clinical Trial (BABY HUG) Follow-up Observational Study II Protocol Sickle Cell Anemia | — | 2012-10-01 |
| Completed | Etidronate for Arterial Calcifications Due to Deficiency in CD73 (ACDC) Arterial Calcification, CD73 Deficiency | Phase 2 | 2012-08-20 |
| Active Not Recruiting | Eltrombopag With Standard Immunosuppression for Severe Aplastic Anemia Severe Aplastic Anemia | Phase 1 / Phase 2 | 2012-07-02 |
| Recruiting | Evaluating New Radiation Techniques for Cardiovascular Imaging Coronary Disease | N/A | 2012-06-21 |
| Completed | Genetics and Pain Severity in Sickle Cell Disease Genotype, Pain, Genetic Variation | — | 2012-06-17 |
| Completed | Clofarabine Followed By Lenalidomide for High-Risk Myelodysplastic Syndromes and Acute Myeloid Leukemia Myeldysplastic Syndrome (MDS), Chronic Myelomonocytic Leukemia, Bone Marrow Diseases | Phase 1 | 2012-06-06 |
| Completed | Microvessels and Heart Problems in Sickle Cell Disease Sickle Cell Disease | — | 2012-04-30 |
| Completed | Blood Flow and Pain Crises in People With Sickle Cell Disease Sickle Cell Disease | — | 2012-03-21 |
| Withdrawn | Imatinib and Carvedilol for High Blood Pressure in the Lungs in Adults With Sickle Cell Disease Pulmonary Hypertension | Phase 1 | 2012-03-02 |
| Completed | Extension Study (Extended Access) of Cyclosporine Inhalation Solution (CIS) in Lung Transplant and Hematopoiet Bronchiolitis Obliterans, Constructive Bronchiolitis, Graft Versus Host Disease | Phase 2 | 2012-03-02 |
| Completed | Hemoglobin and Iron Recovery Study Recovery of Hemoglobin and Iron Stores After Blood Donation | Phase 2 | 2012-03-01 |
| Terminated | Stem Cell Injection to Treat Heart Damage During Open Heart Surgery Heart Disease, Ischemic Heart Disease, Coronary Artery Disease | Phase 1 | 2012-02-29 |
| Terminated | Mutations Associated With Parkinson s Disease Parkinson's Disease | — | 2012-02-27 |
| Terminated | Heart Imaging in Children With Muscular Dystrophy Muscular Dystrophy | — | 2012-02-24 |
| Completed | Carbon Monoxide Levels and Sickle Cell Disease Severity Sickle Cell Disease, Sickle Cell Anemia, Anemia, Sickle Cell | — | 2012-01-26 |
| Completed | Improving Blood Stem Cell Collection and Transplant Procedures Myelodysplastic Syndrome (MDS), Chronic Myelogenous Leukemia, Acute Lymphoblastic Leukemia | Phase 1 / Phase 2 | 2012-01-13 |
| Active Not Recruiting | PCI-32765 for Special Cases of Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Leukemia, Leukemia, Lymphocytyc, CLL (Chronic Lymphocytic Leukemia) | Phase 2 | 2012-01-05 |
| Completed | Simplified Cardiovascular Management Study Cardiovascular Disease | N/A | 2012-01-01 |
| Completed | Bone Marrow Stromal Cell Infusions for Stem Cell Transplant Complications Graft-Versus-Host Disease | Phase 1 | 2011-11-14 |
| Terminated | Pericardiocentesis With Magnetic Resonance Imaging Cardiac Magnetic Resonance Imaging | Phase 1 | 2011-11-08 |
| Completed | Ultra Low Dose Interleukin-2 in Healthy Volunteers Hematologic Diseases | Phase 1 | 2011-09-28 |
| Terminated | Ultrasound and Other Images of Artery Blockages Atherosclerosis | — | 2011-07-29 |
| Completed | Danazol for Genetic Bone Marrow and Lung Disorders Aplastic Anemia | Phase 1 / Phase 2 | 2011-07-19 |
| Completed | Decitabine for High-Risk Sickle Cell Disease Neutropenia, Sickle Cell Disease | Phase 2 | 2011-06-01 |
| Completed | Cross-sectional Characterization of Idiopathic Bronchiectasis Infection, Bronchial Diseases, Respiratory Tract Diseases | — | 2011-04-26 |
| Active Not Recruiting | Eltrombopag for Moderate Aplastic Anemia Moderate Aplastic Anemia, Unilineage Bone Marrow Failure Disorders | Phase 2 | 2011-04-01 |
| Completed | Topical Sodium Nitrite for Chronic Leg Ulcers in Adult Patients With Blood Disorders Sickle Cell Anemia, Sickle Cell Disease, Chronic Hemolytic Disorders | Phase 1 | 2011-03-15 |
| Completed | A Pilot Study of a Thrombopoietin-Receptor Agonist, Eltrombopag, in Patients With Low to Int-2 Risk Myelodyspl Myelodysplastic Syndromes, Thrombocytopenia | Phase 2 | 2011-03-15 |
| Completed | Real-time MRI Right Heart Catheterization Using Passive Catheters Caridovascular Disease, Congenital Heart Disease, Pulmonary Hypertension | Phase 1 / Phase 2 | 2011-02-23 |
| Completed | Cyclosporine Inhalation Solution (CIS) in Lung Transplant and Hematopoietic Stem Cell Transplant Recipients fo Constrictive Bronchiolitis, Bronchiolitis Obliterans, Graft vs Host Disease | Phase 2 | 2011-01-29 |
| Completed | Effects of Systemically Administered Hydrocortisone on the Immune System in Healthy Volunteers Immunosuppression, Healthy, Healthy Subjects | — | 2011-01-21 |
| Recruiting | Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Sy Severe Aplastic Anemia, MDS (Myelodysplastic Syndrome) | Phase 2 | 2010-12-10 |
| Completed | Systolic Blood Pressure Intervention Trial Hypertension | N/A | 2010-10-01 |
| Completed | Randomized Trial of Imaging Versus Risk Factor-Based Therapy for Plaque Regression Atherosclerosis, Hypercholesterolemia | Phase 4 | 2010-09-30 |
| Completed | A Pilot Study of Fludarabine Plus Cyclophosphamide in Refractory Severe Aplastic Anemia Aplastic Anemia, Neutropenia, Pancytopenia | Phase 1 / Phase 2 | 2010-08-01 |
| Completed | Cyclophosphamide Plus Cyclosporine in Treatment-Naive Severe Aplastic Anemia Aplastic Anemia, Neutropenia, Pancytopenia | Phase 1 / Phase 2 | 2010-08-01 |
| Recruiting | Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiova Metabolic Disease, Obesity, Li-Fraumeni Syndrome | — | 2010-07-21 |
| Completed | Effects of Rosuvastatin on the Immune System in Healthy Volunteers With Normal Cholesterol Healthy Volunteers, Statins, Immune Modulation | — | 2010-07-01 |
| Completed | Ofatumumab-based Induction Chemoimmunotherapy in Previously Untreated Patients With CLL/SLL Small Lymphocytic Lymphoma, CLL (Chronic Lymphocytic Leukemia) | Phase 2 | 2010-07-01 |
| Completed | A Study of the Kinetics of Lymphoid Cells in Patients With Monoclonal B-cell Lymphocytosis (MBL), Chronic Lymp Lymphoma, Mantle-cell, CLL (Chronic Lymphocytic Leukemia), Monoclonal B-Cell Lymphocytosis | — | 2010-06-03 |
| Completed | Gardasil Vaccination in Post Stem Cell Transplant Patients Gardasil Vaccine, Stem Cell Transplant, Immunogenicity | Phase 1 | 2010-06-02 |
| Completed | Stem Cell Transplant With Lenalidomide Maintenance in Patients With Multiple Myeloma (BMT CTN 0702) Multiple Myeloma | Phase 3 | 2010-05-01 |
| Unknown | Fish Oil In Heart Transplantation Myocardial Tissue in Heart Transplantation | N/A | 2010-04-01 |
| Completed | Evaluation of Oral Alpha-Cyclodextrin for Decreasing Serum Cholesterol Cardiovascular Disease | Phase 2 | 2010-03-01 |
| Completed | New Techniques to Evaluate Mitral Regurgitation Mitral Valve Regurgitation | — | 2010-02-01 |
| Terminated | Statins for Acutely Injured Lungs From Sepsis Sepsis, Acute Lung Injury | Phase 3 | 2010-01-01 |
| Active Not Recruiting | Haploidentical PBMC Transplant for Severe Congenital Anemias Sickle Cell Anemia | Phase 1 / Phase 2 | 2009-12-14 |
| Completed | Cardiac MRI for Patients Enrolled in INFUSE-AMI Acute Myocardial Infarction, Coronary Artery Disease, Myocardial Fibrosis | — | 2009-12-10 |
| Completed | Novel Influenza A (H1N1) Surveillance Registry Novel Influenza A, H1N1, Influenza | — | 2009-10-01 |
| Completed | Characterization of the Innate Immune Response in Healthy NIH Employees at Baseline and After Immunization Wit Healthy Volunteers | — | 2009-09-30 |
| Completed | A Randomized, Placebo-Controlled, Double-Blind Pilot Study of Pioglitazone Hydrochloride in Severe, Refractory Severe, Refractory Asthma, Airway Inflammation, Airflow Obstruction | Phase 2 | 2009-09-23 |
| Completed | Cellular and Molecular Characterization of the Immune Response in Healthy NIH Employees atBaseline, and After Healthy Volunteers, Influenza | — | 2009-09-18 |
| Completed | Collection of Blood, Bone Marrow, and Buccal Mucosa Samples From Healthy Volunteers for Center for Human Immun Healthy Volunteers | — | 2009-09-09 |
| Completed | Clarification of Optimal Anticoagulation Through Genetics Stroke, Venous Thrombosis, Atrial Fibrillation | Phase 3 | 2009-09-01 |
| Completed | Horse ATG/CsA in Aplastic Anemia Patients Unresponsive to or With a Suboptimal Response to Rabbit ATG/CsA Trea Anemia, Aplastic, Anemia, Hypoplastic | Phase 2 | 2009-08-31 |
| Completed | Screening Protocol for Subjects Being Evaluated for Center for Human Immunology, Autoimmunity, and Inflammator Inflammatory Disease, Autoimmune Disease, Immunologic Disease | — | 2009-08-06 |
| Completed | X-ray Fluoroscopy Fused With Computed Tomography (XFC) Technical Development Aortic Valve Stenosis | — | 2009-08-06 |
| Recruiting | Natural History of Bronchiectasis Bronchiectasis, Cystic Fibrosis, Autoimmune Disease | — | 2009-08-01 |
| Completed | Comparison of Cardiac Computed Tomography and Vasodilator Stress Magnetic Resonance Imaging Perfusion in Patie Coronary Artery Disease | — | 2009-07-01 |
| Completed | A Pilot Study of the Thrombopoietin-Receptor Agonist Eltrombopag in Refractory Aplastic Anemia Patients Anemia, Aplastic, Anemia, Hypoplastic, Thrombocytopenia | Phase 2 | 2009-05-29 |
| Unknown | Examining the Cognitive Benefits of Cardiac Rehabilitation in People With Heart Failure (The CHF CaRe Study) Heart Failure | — | 2009-04-01 |
| Unknown | DHA Supplements to Improve Insulin Sensitivity in Obese Pregnant Women (The Omega-3 Pregnancy Study) Overweight and Obesity, Insulin Resistance, Diabetes, Gestational | Phase 1 | 2009-04-01 |
| Unknown | A Web-Based Cardiovascular Intervention for the Workplace Cardiovascular Diseases | Phase 1 | 2009-04-01 |
| Completed | A Pilot Study of the Safety and Activity of Escalating Doses of ON 01910.Na in Patients With Relapsed Mantle C Lymphoma, Mantle-cell, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Hairy Cell | Phase 1 | 2009-03-05 |
| Completed | Mismatched Donor Lymphocyte Infusions for Relapsed Disease Following Allogeneic Stem Cell Transplantation Leukemia, Myeloid, Acute, Leukemia, Lymphoblastic, Acute, Leukemia, Myelocytic, Chronic | N/A | 2009-02-01 |
| Completed | Pilot Study of Mitochondrial Biology in Human Platelets Insulin Resistance, Diabetes | — | 2009-01-27 |
| Completed | Long-term Oxygen Treatment Trial Chronic Obstructive Pulmonary Disease | Phase 3 | 2009-01-01 |
| Completed | Collection of Blood and Bone Marrow Samples From Select Patients With CML to Measure Minimal Residual Disease Leukemia | — | 2008-12-29 |
| Completed | Improving Neurologic Outcomes in People With Diabetes Who Are Undergoing Heart Surgery Diabetes Mellitus, Cardiovascular Diseases | Phase 3 | 2008-12-01 |
| Completed | Neuropsychological Effects of Immunosuppressive Treatment in Subjects With Aplastic Anemia Aplastic Anemia | — | 2008-09-23 |
| Completed | Identification of Risk Factors for Arrhythmia in Children and Adolescents With Hypertrophic Cardiomyopathy Hypertrophic Cardiomyopathy (HCM) | — | 2008-09-05 |
| Completed | Multisystemic Therapy to Reduce Health Disparities in Adolescents With Asthma Asthma | N/A | 2008-09-01 |
| Completed | Long-Term Effects of Hydroxyurea in Children With Sickle Cell Anemia (The BABY HUG Follow-up Study) Anemia, Sickle Cell | — | 2008-09-01 |
| Terminated | Transfusion-Associated Microchimerism in Previously Injured Individuals Who Received a Blood Transfusion Chimerism, Blood Transfusion, Wounds and Injuries | — | 2008-08-01 |
| Completed | Natural Killer Cells and Bortezomib to Treat Cancer Chronic Myeloid Leukemia (CML), Pancreatic Ca, Colon/Rectal Ca | Phase 1 | 2008-08-01 |
| Terminated | Technical Development of Interventional Cardiovascular Magnetic Resonance Imaging in Normal Volunteers Healthy | — | 2008-07-18 |
| Completed | Screening for Subjects to Participate in Studies of Blood Disorders Bone Marrow Transplant, Sickle Cell Disease, G-CSF | — | 2008-07-03 |
| Recruiting | Natural History Study of Monoclonal B Cell Lymphocytosis (MBL), Chronic Lymphocytic Leukemia/Small Lymphocytic Waldenstrom Macroglobulinemia, Lymphoplasmacytic Lymphoma, Monoclonal B-Cell Lymphocytosis | — | 2008-05-29 |
| Completed | Stem Cell Transplant Using Peripheral and Cord Blood Stem Cells to Treat Severe Aplastic Anemia and Myelodyspl Myelodysplastic Syndrome (MDS) With Refractory Anemia (RA), Severe Aplastic Anemia (SAA) | Phase 2 | 2008-05-21 |
| Completed | Effects of Worksite Wellness Interventions on Vascular Function, Insulin Sensitivity and High-Density Lipoprot Atherosclerosis, Diabetes Mellitus, Obesity | Phase 2 | 2008-04-08 |
| Completed | Evaluation of Toxicity From Stem Cell Transplant Organ Dysfunction, Hemolysis | — | 2008-02-29 |
| Terminated | Biomarkers in Exhaled Breath From Asthmatic Patients Asthma | — | 2008-02-29 |
| Completed | Secondary Pulmonary Hypertension in Adults With Sickle Cell Anemia Pulmonary Hypertension, Sickle Cell Anemia, Sickle Cell Disease | — | 2008-02-19 |
| Terminated | Cardiovascular Disease Screening Congenital Heart Disease, Atherosclerosis, Myocardial Ischemia | — | 2008-01-28 |
| Withdrawn | Pioglitazone Hydrochloride (Actos(Registered Trademark)) to Treat Asthma Asthma, Airway Inflammation, Airflow Obstruction | Phase 2 | 2008-01-04 |
| Completed | Pilot Study to Assess the Proteome in Human Atrial Tissue Diabetes, Cardiomyopathy | — | 2007-12-14 |
| Completed | Early Versus Delayed Enteral Feeding to Treat People With Acute Lung Injury or Acute Respiratory Distress Synd Respiratory Distress Syndrome, Adult | Phase 3 | 2007-12-01 |
| Terminated | Early Versus Delayed Enteral Feeding and Omega-3 Fatty Acid/Antioxidant Supplementation for Treating People Wi Respiratory Distress Syndrome, Adult | Phase 3 | 2007-12-01 |
| Completed | Relation of White Blood Cell Function to Diabetes Diabetes | — | 2007-11-27 |
| Completed | National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions Marfan Syndrome, Turner Syndrome, Ehlers-Danlos Syndrome | — | 2007-11-01 |
| Completed | Effect of Fasting on the Size of Abdominal Lymphatic Tumors in Women Lymphangioleiomyomas, Tuberous Sclerosis, Lymphangioleiomyomatosis | — | 2007-10-26 |
| Completed | Safety of ON 01910.Na in Patients With Myelodysplasia Myelodysplastic Syndrome (MDS) | Phase 1 | 2007-09-14 |
| Completed | Role of Nitric Oxide in Malaria Malaria, Pulmonary Hypertension | — | 2007-09-04 |
| Completed | Longitudinal Studies of HIV-Associated Lung Infections and Complications (Lung HIV) Pulmonary Complications, HIV Infections | N/A | 2007-09-01 |
| Completed | Association Between Abdominal Body Composition, Inflammation, and Risk for Cardiovascular Disease (The MESA AB Cardiovascular Diseases, Obesity | — | 2007-09-01 |
| Recruiting | Collection of Lung Fluid and Tissue Samples for Research Leukocyte Disorders, Respiratory Tract Diseases, Bronchoscopy | — | 2007-08-17 |
| Terminated | Establishing a Repository of Blood and DNA Samples From People With Sickle Cell Disease (Comprehensive Sickle Anemia, Sickle Cell | — | 2007-08-01 |
| Completed | Effectiveness of Etanercept for Idiopathic Pneumonia Syndrome Following Stem Cell Transplantation (BMT CTN 040 Pneumonia, Idiopathic Pneumonia Syndrome | Phase 3 | 2007-08-01 |
| Terminated | Drug Study of Albuterol to Treat Acute Lung Injury Respiratory Distress Syndrome, Adult | Phase 2 / Phase 3 | 2007-08-01 |
| Completed | Niacin to Improve Blood Flow in People With Sickle Cell Disease Sickle Cell Disease | Phase 2 | 2007-07-24 |
| Completed | Genes Causing Ebstein's Anomaly Heart Septal Defects, Ventricle, Heart Defects, Congenital, Double Outlet Right Ventricle | — | 2007-07-03 |
| Completed | Pulmonary Hypertension, Hypoxia and Sickle Cell Disease Chuvash Polycythemia, Cerebrovascular Disease, Pulmonary Hypertension | — | 2007-06-28 |
| Terminated | Sildenafil Therapy for Pulmonary Hypertension and Sickle Cell Disease Sickle Cell Disease, Pulmonary Hypertension | Phase 2 | 2007-06-01 |
| Completed | Peptide Vaccinations to Treat Patients With Low-Risk Myeloid Cancers Myelodysplastic Syndrome (MDS), Acute Myeloid Leukemia (AML), Chronic Myeloid Leukemia (CML) | Phase 2 | 2007-06-01 |
| Completed | Imaging of Totally Blocked Arteries Atherosclerosis, Peripheral Artery Disease, Intermittent Claudication | Phase 1 | 2007-04-05 |
| Completed | Effectiveness of an Anger and Stress Management Program on Reducing Blood Pressure Levels in Youth Cardiovascular Diseases, Hypertension | Phase 2 | 2007-04-01 |
| Completed | Stem Cell Transplantation for Patients With Cancers of the Blood CML (Chronic Myelogenous Leukemia), CLL (Chronic Lymphocytic Leukemia), AML (Acute Myelogenous Leukemia) | Phase 2 | 2007-04-01 |
| Completed | Model System for Transient Forearm Blood Vessel Dysfunction Limb Ischemia, Ischemic Preconditioning | Phase 1 / Phase 2 | 2007-03-26 |
| Recruiting | Collection and Analysis of Blood, Bone Marrow, and Buccal Mucosa Samples From Healthy Volunteers Healthy Volunteers | — | 2007-03-03 |
| Completed | Using Differences in Peripheral Blood Leukocyte Gene Expression to Determine Cardiovascular Disease Risk Atherosclerosis, Cardiovascular Diseases | — | 2007-03-01 |
| Completed | Wilm's Tumor 1 (WT1) Peptide Vaccine for High Risk Hematologic Malignancy Myelodysplastic Syndrome, Acute Myeloid Leukemia (AML), Chronic Myeloid Leukemia (CML) | Phase 2 | 2007-02-01 |
| Completed | Role of p53 Gene in Metabolism Regulation in Patients With Li-Fraumeni Syndrome Mitochondrial Disorders, Li-Fraumeni Syndrome, Carriers of p53 Mutation | — | 2007-01-23 |
| Completed | Collection of Heart Tissue Sample During Open Heart Surgery Ischemia | — | 2007-01-11 |
| Completed | Validation of MRI Measurement of Cardiac Blood Flow Coronary Artery Disease | — | 2006-12-29 |
| Completed | Rilonacept to Improve Artery Function in Patients With Atherosclerosis Coronary Artery Disease, Atherosclerosis, Inflammation | Phase 2 | 2006-12-01 |
| Completed | Dexamethasone to Prevent Oral Chronic Graft-versus-Host Disease Graft vs Host Disease | Phase 2 | 2006-11-24 |
| Completed | Genetic Disorders of Mucociliary Clearance in Nontuberculous Mycobacterial Lung Disease Cystic Fibrosis, Pseudohypoaldosteronism, Nontuberculous Mycobacterial Infection | — | 2006-10-17 |
| Completed | Alemtuzumab (Campath) to Treat T-Large Granular Lymphocyte Leukemia T-LGL Lymphoproliferative Disorders | Phase 2 | 2006-10-17 |
| Unknown | Effectiveness of Combining Light and Non-Light Treatments for Jet Lag and Sleep Disorders Sleep Disorders, Circadian Rhythm | N/A | 2006-10-01 |
| Completed | Catheter-Based Treatment of Cardiovascular Disease Obstructive Coronary Artery Disease, Obstructive Peripheral Artery Disease, Structural Heart Disease | N/A | 2006-09-20 |
| Completed | Role of Helicobacter Pylori and Its Toxins in Lung and Digestive System Diseases Pulmonary Disease, Oropharyngeal Disease, Lymphangioleiomyomatosis | — | 2006-09-18 |
| Completed | Methods to Enhance the Safety and Effectiveness of Stem Cell Transplants Chronic Myelogenous Leukemia, Acute Myelogenous Leukemia, Chronic Lymphocytic Leukemia | Phase 2 | 2006-09-01 |
| Completed | Preschool Based Obesity Prevention Effectiveness Trial Cardiovascular Diseases, Heart Diseases, Obesity | N/A | 2006-09-01 |
| Completed | Lower But More Frequent Dose Rituximab to Treat Chronic Lymphocytic Leukemia Refractory Chronic Lymphocytic Leukemia | Phase 1 | 2006-08-10 |
| Completed | Predicting Response to Cardiac Resynchronization Therapy in Heart Failure Heart Failure, Left Ventricular Dysfunction | — | 2006-07-28 |
| Completed | Cardiovascular Magnetic Resonance Imaging of Pediatric Normal Volunteers Healthy | — | 2006-07-14 |
| Completed | Cardiopulmonary Function Assessment and NO-Based Therapies for Patients With Hemolysis-Associated Pulmonary Hy Pulmonary Hypertension | Phase 1 | 2006-07-09 |
| Withdrawn | HEARTS: Heart, Exercise, and Resistance Training Study Cardiovascular Diseases, Heart Failure, Congestive, Heart Diseases | N/A | 2006-07-01 |
| Completed | The Link Between Anemia and Deficits in Memory and Attention in Individuals With Sickle Cell Disease Sickle Cell Disease | — | 2006-07-01 |
| Completed | Lifetime Risk for Cardiovascular Disease Among Non-White Ethnic Groups Cardiovascular Diseases, Coronary Disease, Heart Failure, Congestive | — | 2006-07-01 |
| Completed | Genetic and Nutritional Causes of Heart Birth Defects Heart Defects, Congenital | — | 2006-07-01 |
| Completed | Pulmonary Hypertension in Patients With Sickle Cell Disease in Nigeria Secondary Pulmonary Arterial Hypertension, Sickle Cell Disease, Pulmonary Hypertension | — | 2006-06-15 |
| Completed | An Evaluation of Safety and Efficacy of Escalating Doses of AMD3100 to Mobilize CD34+ Cells in Healthy Volunte Healthy Volunteers | Phase 1 | 2006-06-14 |
| Completed | Telomere Repair Gene Mutation in Inflammatory Bowel Disease Inflammatory Bowel Disease | — | 2006-05-15 |
| Terminated | Sildenafil to Treat HIV-Associated Pulmonary Hypertension HIV | Phase 1 | 2006-05-12 |
| Completed | Endothelial Progenitor Cells and Nitric Oxide in Cardiac Rehabilitation Program Participants Coronary Artery Disease (CAD) | — | 2006-03-23 |
| Terminated | Childhood Asthma Research and Education (CARE) Network Trial - Montelukast or Azithromycin for Reduction of In Asthma | Phase 4 | 2006-03-01 |
| Unknown | Tailored Videos to Reduce Tobacco Smoke Exposure Among Pregnant Women and Newborns Cardiovascular Diseases, Heart Diseases | N/A | 2006-02-01 |
| Completed | Coated Endotracheal Tube and Mucus Shaver to Prevent Hospital-Acquired Infections Infection | Phase 2 | 2006-01-27 |
| Completed | Atorvastatin to Treat Pulmonary Sarcoidosis Sarcoidosis, Pulmonary | Phase 2 | 2006-01-01 |
| Active Not Recruiting | Hispanic Community Health Study / Study of Latinos Cardiovascular Disease | — | 2006-01-01 |
| Completed | Safety of Peptide Vaccination for Patients With Myelodysplastic Syndrome Myelodysplastic Syndrome (MDS) | Phase 1 | 2005-12-22 |
| Completed | Hydroxyurea and Erythropoietin to Treat Sickle Cell Anemia Sickle Cell Disease, Chronic Kidney Disease, Pulmonary Hypertension | Phase 1 | 2005-12-21 |
| Completed | Rituxan/BEAM vs Bexxar/BEAM in Autologous Hematopoietic Stem Cell Transplant for Non-Hodgkin's Lymphoma (BMTCT Lymphoma, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Non-Hodgkin | Phase 3 | 2005-12-01 |
| Completed | Three Immunosuppressive Treatment Regimens for Severe Aplastic Anemia Immunosuppresion, Thrombocytopenia, Pancytopenia | Phase 2 | 2005-11-28 |
| Completed | The Role of Nitrite in Preconditioning Mediated Tolerance to Ischemic Stress Ischemic Stress, Transient Non-Lethal Ischemia | Phase 1 | 2005-11-01 |
| Completed | Effect of Regular Exercise on Vascular Function and Cardiovascular Risk in a Sedentary Work Force Vascular Formation | Phase 2 | 2005-10-26 |
| Completed | Alemtuzumab to Treat Severe Aplastic Anemia Severe Aplastic Anemia, Refractory, Severe Aplastic Anemia, Relapse | Phase 2 | 2005-09-15 |
| Completed | Genomics of In-Stent Restenosis In-Stent Restenosis, Vascular Disease | — | 2005-09-01 |
| Completed | Rituximab to Treat Moderate Aplastic Anemia, Pure Red Cell Aplasia, or Diamond Blackfan Anemia Anemia, Aplastic, Red-Cell Aplasia, Pure, Anemia, Diamond-Blackfan | Phase 2 | 2005-09-01 |
| Completed | Epidemiology of Depression and Heart Failure in Aging Cardiovascular Diseases, Heart Diseases, Heart Failure | — | 2005-09-01 |
| Completed | Treatment for Acute Graft-Versus-Host Disease (BMT CTN 0302) Graft vs Host Disease, Immune System Disorders | Phase 2 | 2005-09-01 |
| Completed | Eculizumab to Treat Paroxysmal Nocturnal Hemoglobinuria Paroxysmal Hemoglobinuria, Nocturnal | Phase 3 | 2005-08-09 |
| Completed | Air Pollution, Inflammation, and New Onset Asthma Asthma, Lung Diseases | — | 2005-08-01 |
| Completed | A Pilot Study of Alemtuzumab (Campath[R]) in Patients With Myelodysplastic Syndrome Myelodysplastic Syndromes | Phase 2 | 2005-07-21 |
| Withdrawn | Metoclopramide to Treat Anemia in Patients With Myelodysplastic Syndrome (MDS) Myelodysplastic Syndromes | Phase 2 | 2005-07-14 |
| Completed | Interagency Registry for Mechanically Assisted Circulatory Support (Intermacs) Cardiovascular Diseases, Heart Diseases, Heart Failure, Congestive | — | 2005-06-01 |
| Completed | Acute Myeloid Leukemia T Cell Depletion to Improve Transplants in Adults With Acute Myeloid Leukemia (BMT CTN Leukemia, Myelocytic, Acute | Phase 2 | 2005-06-01 |
| Completed | Safety and Dosing Evaluation of REG1 Anticoagulation System Healthy | Phase 1 | 2005-06-01 |
| Completed | Heart Function and Exercise Capacity in Patients With Hypertrophic Cardiomyopathy Angina, Unstable, Myocardial Infarction, Ischemic Heart Disease | — | 2005-05-27 |
| Recruiting | Long-term Evaluation and Follow-up Care of Patients Treated With Stem Cell Transplants Graft-versus-leukemia, Graft vs Host Disease, Graft Rejection | — | 2005-04-22 |
| Completed | Biomarkers for Cardiovascular Disease Coronary Artery Disease | — | 2005-04-19 |
| Terminated | Effect of Nitrite on Exercise Physiology and Metabolism Healthy, Healthy Volunteer, HV | Phase 1 | 2005-03-08 |
| Terminated | Establishing a Database of People With Sickle Cell Disease (Comprehensive Sickle Cell Centers Collaborative Da Anemia, Sickle Cell | — | 2005-03-01 |
| Completed | Cytokine Gene Polymorphisms in Bone Marrow Failure Bone Marrow Diseases | — | 2005-02-11 |
| Completed | 20 Year Changes in Fitness & Cardiovascular Disease Risk - Ancillary to CARDIA Cardiovascular Diseases, Coronary Disease, Diabetes Mellitus | — | 2005-02-01 |
| Completed | Nitrite Infusion Studies Healthy | Phase 1 | 2005-01-19 |
| Completed | Higher-Dose Ezetimibe to Treat Homozygous Sitosterolemia Heart Diseases, Metabolism, Inborn Errors | Phase 3 | 2004-12-01 |
| Completed | Eculizumab to Treat Paroxysmal Nocturnal Hemoglobinuria Hemoglobinuria, Paroxysmal | Phase 3 | 2004-12-01 |
| Completed | Therapeutic Application of Intravascular Nitrite for Sickle Cell Disease Sickle Cell Anemia | Phase 1 | 2004-11-01 |
| Completed | Sildenafil to Increase Exercise Capacity in Individuals With Idiopathic Pulmonary Fibrosis and Pulmonary Hyper Pulmonary Fibrosis, Hypertension, Pulmonary | Phase 2 | 2004-11-01 |
| Completed | Rosiglitazone to Reverse Metabolic Defects in Diabetes Diabetes Mellitus, Type II, Insulin Resistance | Phase 2 | 2004-10-20 |
| Completed | MRI-Guided Balloon Angioplasty to Treat Blood Flow Blockage in the Legs Cardiovascular Diseases | Phase 1 | 2004-10-20 |
| Completed | Mutations in Genes Associated With Pentalogy of Cantrell Pentalogy of Cantrell | — | 2004-09-15 |
| Completed | STORIES-Stories to Communicate Risk About Tobacco Cardiovascular Diseases, Heart Diseases | N/A | 2004-09-01 |
| Completed | Work, Weight, and Wellness Program: The 3W Program Cardiovascular Diseases, Heart Diseases, Obesity | N/A | 2004-09-01 |
| Completed | Hypertension Education and Treatment Partnership for Reducing Ethnic Differences in the Risk of Cardiovascular Cardiovascular Diseases, Hypertension, Heart Diseases | — | 2004-09-01 |
| Completed | Retrovirus Epidemiology Donor Study-II (REDS-II) Acquired Immunodeficiency Syndrome, Blood Donors, Blood Transfusion | — | 2004-09-01 |
| Completed | Genetic Studies in Difficult to Treat Asthma: TENOR Asthma, Lung Diseases | — | 2004-09-01 |
| Completed | Long-Term Predictors of Morbidity in Older Age Cardiovascular Diseases, Diabetes Mellitus, Heart Diseases | — | 2004-09-01 |
| Completed | Asthma Surveillance and Education in Preschool Settings Asthma | — | 2004-09-01 |
| Completed | Blood Cell Collection for Future Use in Individuals With Fanconi Anemia Fanconi Anemia | N/A | 2004-08-01 |
| Completed | Effect of Nitric Oxide Donor on Endothelial Progenitor Cells in Patients With Coronary Artery Disease Coronary Artery Disease | Phase 2 | 2004-08-01 |
| Unknown | Improving the Results of Bone Marrow Transplantation for Patients With Severe Congenital Anemias Congenital Hemolytic Anemia, Sickle Cell Disease | Phase 1 / Phase 2 | 2004-07-16 |
| Completed | Effects of Exercise Training on Diastolic Heart Function in Postmenopausal Women Heart Failure, Congestive, Cardiovascular Diseases | N/A | 2004-07-01 |
| Completed | Pediatrics:Chlamydia, Sickle Cell Anemia and Stroke Risk - Ancillary to STOP II Blood Disease, Anemia, Sickle Cell, Chlamydia Infections | — | 2004-07-01 |
| Completed | Identifying Low-Risk Patients With Pulmonary Embolism Pulmonary Embolism, Lung Diseases | — | 2004-07-01 |
| Completed | Effect of Exercise on Elevated C-reactive Protein Concentrations in Formerly Inactive Adults Cardiovascular Diseases, Heart Diseases, Obesity | N/A | 2004-07-01 |
| Completed | Logical Analysis of Data and Cardiac Surgery Risk Cardiovascular Diseases, Heart Diseases, Coronary Disease | — | 2004-07-01 |
| Completed | G-CSF and AMD3100 to Mobilize Stem Cells in Healthy Volunteers Healthy | Phase 2 | 2004-06-18 |
| Completed | Genetics and Cardiovascular Reactivity in Young Twins Cardiovascular Diseases, Heart Diseases, Hypertension | — | 2004-06-01 |
| Completed | Accelerated Immunization to Induce Cytomegalovirus Immunity in Stem Cell Donors Cytomegalovirus Infections | Phase 2 | 2004-05-01 |
| Completed | Gene-Specific Responses to Exercise in Discordant Twins Atherosclerosis, Cardiovascular Diseases, Heart Diseases | — | 2004-05-01 |
| Completed | Evaluating the Effects of Hormone Replacement Therapy on Brain Function (The WHIMS-MRI Study) Stroke | — | 2004-05-01 |
| Completed | Effectiveness of the TB Contact Priority Model Tuberculosis | — | 2004-05-01 |
| Recruiting | Natural History of Sickle Cell Disease Pain Crisis | — | 2004-04-29 |
| Recruiting | Genetic Basis of Immunodeficiency Severe Combined Immunodeficiency | — | 2004-04-05 |
| Completed | Atherosclerosis in the Coronary and Carotid Arteries Coronary Disease | — | 2004-04-01 |
| Terminated | Thymic Tolerance in Pediatric Heart Transplantation Heart Transplantation | Phase 2 | 2004-04-01 |
| Completed | EW-A-401 to Treat Intermittent Claudication Intermittent Claudication, Arteriosclerosis | Phase 1 | 2004-03-27 |
| Completed | Estrogen Receptor Variants, HDL, and Atherosclerosis Cardiovascular Diseases, Atherosclerosis, Coronary Arteriosclerosis | — | 2004-03-01 |
| Completed | Childhood Asthma Research and Education (CARE) Network Trial - Acute Intervention Management Strategies (AIMS) Asthma, Lung Diseases | N/A | 2004-02-01 |
| Completed | Imatinib (Gleevec(Registered Trademark)) to Treat Chronic Myelomonocytic Leukemia and Atypical Chronic Myeloge Chronic Myelomonocytic Leukemia, Chronic Myelogenous Leukemia | Phase 2 | 2004-01-14 |
| Completed | Technical Development of Strain Rate Echocardiography Echocardiography, Doppler | — | 2004-01-08 |
| Completed | AMD 3100 (Mozobil Plerixafor) to Mobilize Stem Cells for Donation Healthy | Phase 2 | 2004-01-01 |
| Completed | HYPGENE-Genetics Fitness Obesity & Risk of Hypertension Cardiovascular Diseases, Heart Diseases, Hypertension | — | 2004-01-01 |
| Completed | Stem Cell Transplantation and T-Cell Add-Back to Treat Bone Marrow Malignancies Hematologic Malignancies, Bone Marrow Transplant Rejection | Phase 2 | 2004-01-01 |
| Completed | Cardiac Function in Patients With Hereditary Hemochromatosis Hereditary Hemochromatosis | — | 2003-12-08 |
| Completed | Stem Cell Transplantation in Individuals With Multiple Myeloma (BMT CTN 0102) Multiple Myeloma | Phase 3 | 2003-12-01 |
| Completed | The Role of Heart Stiff and Weak Atrium on Exercise Capacity in Patients With Hypertrophic Cardiomyopathy Cardiomyopathy, Hypertrophic | — | 2003-12-01 |
| Completed | Rabbit Antithymocyte Globulin Versus Campath-1H for Treating Severe Aplastic Anemia Aplastic Anemia | Phase 2 | 2003-11-06 |
| Completed | A Randomized Trial of Recombinant Humanized Anti-IL-2 Receptor Antibody (Daclizumab) Versus Antithymocyte Glob Myelodysplastic Syndromes | Phase 2 | 2003-11-01 |
| Recruiting | Causes and Natural History of Dyslipidemias Hypercholesterolemia, Atherosclerosis | — | 2003-10-14 |
| Recruiting | Collection of Tissue Specimens From Patients With Solid Tumors or Blood Disorders and Their HLA-Compatible Fam Neoplasms, Hematologic Neoplasms, Healthy Volunteers | — | 2003-10-08 |
| Completed | Analyzing Genetic Factors Involved in Blood Pressure Changes Due to Salt and Potassium Intake (The GenSalt Stu Blood Pressure | Phase 3 | 2003-10-01 |
| Completed | Evaluating How the Treatments in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Study Affect D Diabetic Retinopathy | Phase 3 | 2003-10-01 |
| Completed | Dietary Nitrate and Nitrite to Increase Nitric Oxide in Patients With Coronary Artery Disease Coronary Arteriosclerosis | Phase 2 | 2003-09-25 |
| Completed | Pharmacogenetics and Cardiovascular Events Cardiovascular Diseases, Atrial Fibrillation, Cerebrovascular Accident | — | 2003-09-01 |
| Completed | Genomewide Search for Loci Underlying Metabolic Syndrome Metabolic Syndrome X, Cardiovascular Diseases, Heart Diseases | — | 2003-09-01 |
| Completed | Treatment of Persistent Wheezing in Infants and Children Asthma, Respiratory Sounds | N/A | 2003-09-01 |
| Completed | Outcomes of Sleep Disorders in Older Men Cardiovascular Diseases, Heart Diseases, Sleep | — | 2003-09-01 |
| Completed | Inflammatory Genomics in Human Carotid Artery Disease Cardiovascular Diseases, Atherosclerosis, Carotid Artery Diseases | — | 2003-09-01 |
| Completed | Trial of Angiotensin Converting Enzyme Inhibition in Infants With Single Ventricle--Pediatric Heart Network Heart Defects, Congenital, Heart Failure, Congestive | Phase 3 | 2003-08-01 |
| Completed | Technical Development of Cardiovascular Magnetic Resonance Imaging Peripheral Artery Disease | Phase 1 | 2003-07-14 |
| Completed | Rosiglitazone to Treat Patients With Heart Failure and Glucose Intolerance or Type II Diabetes Congestive Heart Failure | Phase 2 | 2003-07-09 |
| Completed | Molecular Epidemiology of Myocardial Infarction and Stroke in Older Adults - Ancillary to CHS Coronary Disease, Cardiovascular Diseases, Heart Diseases | — | 2003-07-01 |
| Completed | Improving Immunosuppressive Treatment for Patients With Severe Aplastic Anemia Severe Aplastic Anemia | Phase 2 | 2003-06-26 |
| Completed | The Framingham Study: Examining DNA Markers and Links to Diseases Vascular Diseases | — | 2003-06-12 |
| Completed | Investigating Cytokine Genes of Stem Cell Donors Stem Cell Transplantation | — | 2003-06-05 |
| Completed | Natural History Study for BEN Neutropenia, Agranulocytosis, Hematologic Diseases | — | 2003-06-03 |
| Completed | Experimental Bone Marrow Transplant Protocol Acute Lymphocytic Leukemia, Chronic Myeloid Leukemia, Acute Myelocytic Leukemia | Phase 2 | 2003-05-19 |
| Completed | Collection of Biological Samples From Patients With Hepatitis-Associated Aplastic Anemia Hepatitis-Associated Aplastic Anemia | — | 2003-03-10 |
| Completed | Identification of Genes Predisposing to Atherosclerosis Cardiovascular Diseases, Coronary Disease, Heart Diseases | — | 2003-03-01 |
| Completed | Increasing Physical Activity as Part of a Smoking Cessation Program Smoking Cessation | N/A | 2003-01-01 |
| Completed | The Effect of Exercise on Stem Cell Mobilization and Heart Function in Patients Undergoing Cardiac Rehabilitat Coronary Arteriosclerosis | — | 2003-01-01 |
| Completed | Genetic Epidemiology of CVD Risk Factors Cardiovascular Diseases, Heart Diseases | — | 2003-01-01 |
| Enrolling By Invitation | Blood Collection for Research Related to Certain Diseases Involving Blood Vessels Sickle Cell Disease | — | 2002-11-04 |
| Completed | Identification of Genes Expressed in Atherosclerotic Plaque Atherosclerosis | — | 2002-10-21 |
| Completed | Effects of Nitrite on Blood Vessel Dilation in Normal Volunteers Nitric Oxide, Endothelium-Derived Relaxing Factor, Healthy | Phase 2 | 2002-10-01 |
| Completed | Effects of Lifeskills Workshop on BP in Hypertensive Employees Hypertension | Phase 2 | 2002-09-01 |
| Completed | Cardiac and Renal Disease Study (CARDS) Coronary Disease, Cardiovascular Diseases, Cerebrovascular Accident | — | 2002-09-01 |
| Completed | Center for Reducing Asthma Disparities - Harvard University/Boston Area Community Health Centers Lung Diseases, Asthma | — | 2002-09-01 |
| Completed | Diet, Genetics, and CVD Risk Factor Response in Blacks Cardiovascular Diseases, Heart Diseases | — | 2002-09-01 |
| Completed | Transcranial Doppler (TCD) Ultrasound of Subjects Enrolled in BABY HUG - Ancillary to BABY HUG Blood Disease, Anemia, Sickle Cell, Cerebrovascular Disorders | — | 2002-09-01 |
| Completed | Genetic Epidemiology of Blood Pressure Intervention Cardiovascular Diseases, Heart Diseases, Hypertension | — | 2002-09-01 |
| Completed | Predictors of Recurrent Stroke in the PROGRESS Study Cardiovascular Diseases, Cerebrovascular Accident, Cerebrovascular Disorders | — | 2002-09-01 |
| Completed | The ARIC MRI Study Cardiovascular Diseases, Cerebrovascular Disorders, Cerebrovascular Accident | — | 2002-09-01 |
| Completed | Acipimox to Improve Hyperlipidemia and Insulin Sensitivity Associated With HIV Insulin Resistance, Cardiovascular Diseases, Heart Diseases | N/A | 2002-09-01 |
| Completed | Longitudinal Study of Neighborhood Predictors of CVD Cardiovascular Diseases, Heart Diseases | — | 2002-09-01 |
| Completed | Adherence to Weight Loss for Hypertension in African American Women Cardiovascular Diseases, Heart Diseases, Hypertension | N/A | 2002-09-01 |
| Completed | Conditioned Placebo Effects and Treatment of Hypertension Cardiovascular Diseases, Heart Diseases, Hypertension | Phase 2 | 2002-09-01 |
| Completed | Center for Reducing Asthma Disparities - Howard/Hopkins Centers Asthma, Lung Diseases | — | 2002-09-01 |
| Completed | Center for Reducing Asthma Disparities - Northwestern University/Cook County Hospital Centers Asthma, Lung Diseases | N/A | 2002-09-01 |
| Completed | Home Use of Automatic External Defibrillators to Treat Sudden Cardiac Arrest Cardiovascular Diseases, Myocardial Infarction, Heart Diseases | Phase 3 | 2002-09-01 |
| Completed | Pediatric Asthma Controller Trial (PACT) Asthma, Lung Diseases | Phase 3 | 2002-08-01 |
| Completed | Psychosocial Determinants of Nutrient Intake in Girls Cardiovascular Diseases, Heart Diseases, Obesity | — | 2002-08-01 |
| Completed | Mechanisms of Disability in Peripheral Arterial Disease Cardiovascular Diseases, Arterial Occlusive Diseases, Peripheral Vascular Diseases | — | 2002-08-01 |
| Completed | Stem Cell Mobilization to Treat Chest Pain and Shortness of Breath in Patients With Coronary Artery Disease Coronary Artery Disease | Phase 2 | 2002-08-01 |
| Completed | Stem Cell Transplant Therapy With Campath-1H for Treating Advanced Mycosis Fungoides and Sezary Syndrome Mycosis Fungoides, Sezary Syndrome | Phase 1 / Phase 2 | 2002-07-30 |
| Completed | Guideline Adherence for Heart Health Cardiovascular Diseases, Hypercholesterolemia, Hypertension | Phase 2 | 2002-07-01 |
| Completed | Atrial Fibrillation Incidence, Risk Factors and Genetics Atrial Fibrillation, Cardiovascular Diseases, Heart Diseases | — | 2002-07-01 |
| Completed | Transfer of GPI-Linked Proteins to Transfused Patients With Paroxysmal Nocturnal Hemoglobinuria Paroxysmal Hemoglobinuria | — | 2002-06-01 |
| Terminated | Stem Cell Collection for Adult Volunteers Sickle Cell | — | 2002-04-29 |
| Completed | Monitoring Community Trends in Heart Failure Cardiovascular Diseases, Heart Failure, Congestive, Heart Diseases | — | 2002-04-01 |
| Completed | Immune Response to Cytomegalovirus Cytomegalovirus Infections | — | 2002-04-01 |
| Completed | Alcohol Septal Ablation in Obstructive Hypertrophic Cardiomyopathy: A Pilot Study Hypertrophic Cardiomyopathy | Phase 2 | 2002-04-01 |
| Completed | APEX: Adiposity Prevention by Exercise in Black Girls Cardiovascular Diseases, Heart Diseases, Obesity | — | 2002-04-01 |
| Completed | Genetic Determinants:Low HDL, High Triglycerides, Obesity Cardiovascular Diseases, Atherosclerosis, Hypertriglyceridemia | — | 2002-04-01 |
| Completed | ACE Inhibition and Novel Cardiovascular Risk Factors Cardiovascular Diseases, Heart Diseases, Hypertension | Phase 2 | 2002-02-01 |
| Completed | Stem Cell Transplantation and T-Cell Add-Back to Treat Bone Marrow Malignances Immunosuppression, Leukemia | Phase 2 | 2002-01-23 |
| Completed | Possible Relation of Toll-Like Receptors and Nitric Oxide to Chronic Lung Disease Lung Diseases | — | 2002-01-01 |
| Completed | Magnetic Resonance Imaging of Narrowed Arteries Arteriosclerosis | Phase 1 | 2002-01-01 |
| Completed | Comparison of Two Programs to Encourage Physical Activity in Individuals With Chronic Obstructive Pulmonary Di Pulmonary Disease, Chronic Obstructive, Lung Diseases, Obstructive | Phase 3 | 2002-01-01 |
| Completed | Estrogen, Cytokines and Heart Failure in Women Cardiovascular Diseases, Heart Failure, Congestive, Heart Diseases | N/A | 2001-12-01 |
| Completed | Exposure of Children With Asthma to Household Environmental Tobacco Smoke Asthma, Lung Diseases | — | 2001-12-01 |
| Completed | MRI to Detect Embolism Following Angiography and Angioplasty-Stenting of the Renal Artery Renal Artery Obstruction, Kidney Disease | Phase 1 | 2001-12-01 |
| Completed | Technical Development of Cardiovascular Magnetic Resonance Imaging Cardiomyopathy, Congenital Heart Disease, Cardiovascular Disease | — | 2001-11-26 |
| Completed | Collection and Storage of Umbilical Cord Stem Cells for Treatment of Sickle Cell Disease Sickle Cell Disease, Sickle Cell Trait | — | 2001-11-01 |
| Completed | A Genome-Wide Scan For Quantitative Trait Loci of Serum Bilirubin - A Framingham Study Genetics | — | 2001-10-26 |
| Completed | Cardiac MR of Subclinical CVD: Impact of Age Atherosclerosis, Heart Diseases, Cardiovascular Diseases | — | 2001-09-01 |
| Completed | VA HDL Intervention Trial (VA-HIT) Ancillary Study Data Analysis Coronary Disease, Heart Diseases, Cardiovascular Diseases | — | 2001-09-01 |
| Completed | Blood and Marrow Transplant Clinical Research Network Bone Marrow Transplantation, Blood Disease, Hematopoietic Stem Cell Transplantation | N/A | 2001-09-01 |
| Completed | Measuring Sensitivity to Nonignorability Cardiovascular Diseases, Heart Diseases | — | 2001-09-01 |
| Completed | Patient-Physician Partnership to Improve High Blood Pressure Adherence Cardiovascular Diseases, Hypertension | Phase 4 | 2001-09-01 |
| Completed | Stepped Intervention for Meds Adherence and Blood Pressure Control Cardiovascular Diseases, Heart Diseases, Hypertension | N/A | 2001-09-01 |
| Completed | Genetic Architecture of Heart Disease in Rural Brazil Chagas Disease, Heart Diseases, Arrhythmia | — | 2001-09-01 |
| Completed | Does Shared Decision-Making Improve Adherence in Asthma Lung Diseases, Asthma | N/A | 2001-09-01 |
| Completed | Heavy Metals, Obesity and Cardiovascular Risk - Ancillary to Look AHEAD Diabetes Mellitus, Non-insulin Dependent, Cardiovascular Diseases, Obesity | — | 2001-09-01 |
| Completed | Sleep Apnea in Look AHEAD Participants - Ancillary to Look AHEAD Sleep Apnea Syndromes, Diabetes Mellitus, Non-insulin Dependent, Obesity | — | 2001-09-01 |
| Completed | Prenatal Nutrition and Adult Disease Cardiovascular Diseases, Heart Diseases, Diabetes Mellitus | — | 2001-09-01 |
| Completed | Vascular Interaction With Age in Myocardial Infarction Myocardial Infarction | N/A | 2001-09-01 |
| Completed | Airway Responses Following Chlorine Gas Exposure Asthma, Lung Diseases | — | 2001-09-01 |
| Completed | MRI Derived Organ & Tissue Mass Changes With Weight Loss - Ancillary to Look AHEAD Cardiovascular Diseases, Atherosclerosis, Obesity | — | 2001-09-01 |
| Completed | Postprandial Lipemia and Endothelial Function in ACCORD- Ancillary to ACCORD Atherosclerosis, Cardiovascular Diseases, Hypercholesterolemia | — | 2001-09-01 |
| Completed | Induction of Stable Chimerism for Sickle Cell Anemia Blood Disease, Hematopoietic Stem Cell Transplantation, Anemia, Sickle Cell | Phase 2 | 2001-08-01 |
| Completed | Nitric Oxide and Transfusion Therapy for Sickle Cell Patients With Pulmonary Hypertension Sickle Cell Anemia, Pulmonary Hypertension | Phase 1 | 2001-07-27 |
| Completed | Mechanisms of Pro-Thrombosis in Diabetes Mellitus -- Ancillary to BARI 2D Cardiovascular Diseases, Heart Diseases, Diabetes Mellitus, Non-insulin Dependent | — | 2001-07-01 |
| Completed | Physical Activity, Body Composition, and Prevalent Asthma Asthma, Lung Diseases | — | 2001-07-01 |
| Completed | Behavioral and Immunological Factors in Coronary Disease Cardiovascular Diseases, Coronary Disease, Heart Diseases | — | 2001-07-01 |
| Completed | Epidemiology of Cardiovascular Disease in Diabetes Cardiovascular Diseases, Diabetes Mellitus, Non-insulin Dependent, Heart Diseases | — | 2001-07-01 |
| Completed | The Role of Bacteria and Genetic Variations in Cystic Fibrosis Psuedomas Infection, Cystic Fibrosis | — | 2001-06-20 |
| Completed | Does Shared Decision-Making Improve Asthma Outcomes? Asthma | N/A | 2001-06-01 |
| Terminated | Estrogen Replacement to Reduce Risk of Neurologic Injury After Coronary Artery Bypass Graft Surgery Coronary Disease, Cardiovascular Diseases, Heart Diseases | N/A | 2001-06-01 |
| Completed | Tissue Collection From People With Cystic Fibrosis Cystic Fibrosis | — | 2001-05-02 |
| Completed | Framingham Offspring Study: Psychosocial Risk Factors Cardiovascular Diseases, Coronary Disease, Heart Diseases | — | 2001-05-01 |
| Completed | Selective T-Cell Depletion to Reduce GVHD (Patients) Receiving Stem Cell Tx to Treat Leukemia, Lymphoma or MDS Graft vs Host Disease, Myelodysplastic Syndromes, Leukemia | Phase 2 | 2001-05-01 |
| Completed | New CVD Risk Factors for Lowered Cognitive Functioning Cardiovascular Diseases, Heart Diseases, Hypertension | — | 2001-04-01 |
| Completed | Analysis of Sex Hormones and Lipoproteins in Young Males Cardiovascular Diseases, Atherosclerosis, Heart Diseases | — | 2001-04-01 |
| Completed | Failure Time Methods for Family Disease Studies Heart Diseases, Cardiovascular Diseases, Coronary Disease | — | 2001-04-01 |
| Completed | Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness (ESCAPE) Heart Diseases, Heart Failure, Congestive, Heart Failure | Phase 3 | 2001-04-01 |
| Completed | Genome Scan for Obesity in a Multi-Ethnic Sample Cardiovascular Diseases, Heart Diseases, Obesity | — | 2001-04-01 |
| Completed | Serum Total Homocysteine and C-Reactive Protein - Ancillary to IDNT Cardiovascular Diseases, Atherosclerosis, Heart Diseases | — | 2001-04-01 |
| Completed | Nitric Oxide Inhalation Therapy to Relieve Chest Pain in Patients With Coronary Artery Disease Coronary Disease, Myocardial Ischemia | Phase 2 | 2001-04-01 |
| Completed | ESCAPE Mechanistic Substudies - Ancillary to ESCAPE Cardiovascular Diseases, Heart Diseases, Heart Failure | — | 2001-04-01 |
| Completed | Modification of Allergic Immunologic Response by Leukotriene Antagonists - Ancillary to ACRN IMPACT Asthma, Lung Diseases | — | 2001-04-01 |
| Completed | Non-Traditional Cardiovascular Risk Factors in Type 2 Diabetes Mellitus - Ancillary to VA Study of Glycemic Co Atherosclerosis, Cardiovascular Diseases, Diabetes Mellitus | — | 2001-04-01 |
| Completed | Endothelial Progenitor Cells and Risk Factors for Coronary Artery Disease Coronary Arteriosclerosis | — | 2001-03-01 |
| Completed | Visceral Adiposity and CVD Risk in Women Cardiovascular Diseases, Heart Diseases, Obesity | — | 2001-03-01 |
| Completed | Heart Rate Recovery and Mortality Cardiovascular Diseases, Heart Diseases | — | 2001-03-01 |
| Completed | SCH-58235 (Ezetimibe) to Treat Homozygous Sitosterolemia Lipoidosis | Phase 2 | 2001-03-01 |
| Completed | Pirfenidone to Treat Hypertrophic Cardiomyopathy Hypertrophic Cardiomyopathy | Phase 2 | 2001-02-01 |
| Completed | Mobilization of Stem Cells With G-CSF for Collection From Patients With Diamond-Blackfan Anemia Diamond Blackfan Anemia | Phase 2 | 2001-02-01 |
| Completed | Stem Cell Mobilization Potential in Patients With Aplastic Anemia in Remission Aplastic Anemia | Phase 1 | 2001-02-01 |
| Completed | Blood Factors and Peripheral Arterial Disease Outcomes Arterial Occlusive Diseases, Cardiovascular Diseases, Peripheral Vascular Diseases | — | 2001-01-01 |
| Completed | Prevention of Early Asthma in Kids (PEAK) Asthma, Lung Diseases | N/A | 2001-01-01 |
| Completed | Heart and Skeletal Muscle Problems in Neuroacanthocytosis Choreatic Disorder | — | 2000-12-01 |
| Unknown | Effect of Air Pollution on Long-Term Asthma Severity and Lung Function in Children Asthma | — | 2000-11-01 |
| Completed | Stem Cell Transplantation to Treat Systemic Mastocytosis Mastocytosis | Phase 2 | 2000-10-13 |
| Completed | Phenylbutyrate, Dexamethasone, and Sargramostim in Treating Patients With Refractory or Relapsed Acute Myeloid Leukemia | Phase 2 | 2000-10-01 |
| Active Not Recruiting | The Jackson Heart Study of Cardiovascular Disease Among African Americans Cardiovascular Diseases, Heart Diseases, Atherosclerosis | — | 2000-09-19 |
| Completed | Genetic Architecture of Plasma T-PA and PAI-1 Cardiovascular Diseases, Heart Diseases, Thrombosis | — | 2000-09-01 |
| Completed | Sex Steroid Hormones and Risk of CHD in Women Cardiovascular Diseases, Heart Diseases, Coronary Disease | — | 2000-09-01 |
| Completed | CV Risk Factors at Age 25-64 & Long-Term Medicare Costs Cardiovascular Diseases, Heart Diseases | — | 2000-09-01 |
| Completed | Risk of Coronary Heart Disease in Women With Polycystic Ovary Syndrome Atherosclerosis, Cardiovascular Diseases, Heart Diseases | — | 2000-09-01 |
| Completed | Myocardial Perfusion, Risk Factors, and Coronary Calcium Cardiovascular Diseases, Coronary Arteriosclerosis, Coronary Disease | — | 2000-09-01 |
| Completed | Chronic Life Stress and Incident Asthma in Adult Women Asthma, Lung Diseases | — | 2000-09-01 |
| Completed | Chromosome 5Q Gene Variants and Asthma-Related Traits Asthma, Lung Diseases | — | 2000-09-01 |
| Completed | Identifying Genes That May Increase the Risk for Heart Disease in African Americans Heart Diseases | — | 2000-09-01 |
| Completed | Prospective Investigation of Pulmonary Embolism Diagnosis (PIOPED II) Lung Diseases, Pulmonary Embolism, Venous Thromboembolism | N/A | 2000-09-01 |
| Completed | Risk Factors for CV Disease in a Dialysis Cohort Cardiovascular Diseases, Heart Diseases, Atherosclerosis | — | 2000-09-01 |
| Completed | Randomized Trial to Reduce Environmental Tobacco Smoke in Children With Asthma Asthma, Lung Diseases | Phase 3 | 2000-09-01 |
| Completed | Assessing the Occupation Burden in COPD Lung Diseases, Obstructive, Chronic Obstructive Pulmonary Disease | — | 2000-09-01 |
| Completed | Factors Associated With Coronary Heart Disease in African Americans in the Jackson Heart Study Cardiovascular Diseases, Coronary Disease | — | 2000-09-01 |