Trials / Terminated
TerminatedNCT00151164
Thymic Tolerance in Pediatric Heart Transplantation
- Status
- Terminated
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 48 (estimated)
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI) · NIH
- Sex
- All
- Age
- 1 Day – 20 Years
- Healthy volunteers
- Not accepted
Summary
The investigators hypothesize that injecting donor bone marrow cells into the recipient thymus gland at the time of heart transplantation in children will prove to be feasible and safe. They further hypothesize that recipients receiving donor bone marrow will experience less acute rejection events with reduced long-term requirements for immunosuppressive medications when compared to controls who do not receive marrow but who are managed under an identical immunosuppressive protocol.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | donor bone marrow cell injection into thymus gland |
Timeline
- Start date
- 2004-04-01
- Primary completion
- 2007-10-01
- Completion
- 2007-10-01
- First posted
- 2005-09-08
- Last updated
- 2016-07-12
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT00151164. Inclusion in this directory is not an endorsement.