NCT06934876

Waveform Capnography Compared to Colorimetric Carbon Dioxide Detection During Tracheal Intubation of Critically Ill Adults

Waveform Capnography and Colorimetric Carbon Dioxide Detection During Tracheal Intubation of Critically Ill Adults

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 1,332 (estimated)
• Sponsor: Brian Driver · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study will compare the sensitivity and specificity of waveform capnography versus colorimetric carbon dioxide detection to identify tracheal placement of the endotracheal tube during intubation of critically ill adults.

Conditions

• Acute Respiratory Failure

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Colorimetric carbon dioxide (CO2) detection	All patients will undergo colorimetric carbon dioxide (CO2) detection. The reading will be assessed by a clinician at the bedside who will answer yes or no to the following question, asked after 7 breaths have been delivered following intubation: "Is the color change consistent with a tube located in the trachea?"
DIAGNOSTIC_TEST	Waveform capnography	All patients will undergo waveform capnography. The reading will be assessed by a clinician at the bedside who will answer yes or no to the following question, asked after 7 breaths have been delivered following intubation: " Is the waveform consistent with a tube located in the trachea?"

Timeline

• Start date: 2025-04-21
• Primary completion: 2026-12-01
• Completion: 2027-01-01
• First posted: 2025-04-18
• Last updated: 2025-11-04

Locations

6 sites across 1 country: United States