| Not Yet Recruiting | The AminoECMO Pilot Trial Acute Kidney Injury | Phase 2 | 2026-02-01 |
| Not Yet Recruiting | Restricted or Liberal Fluid for Haemodynamic Resuscitation in Sepsis Septic Shock, Fluid Resuscitation | — | 2025-11-01 |
| Not Yet Recruiting | Improving Survivorship for Critically Ill Patients Aged 65 and Over Critical Illness, Recovery Outcomes, Care Coordination | Phase 3 | 2025-11-01 |
| Not Yet Recruiting | RECOMMEND Platform Trial Extracorporeal Membrane Oxygenation Complication, ARDS (Acute Respiratory Distress Syndrome), Intensive Care Medicine | Phase 3 | 2025-09-01 |
| Recruiting | Nutrition Practice in Critically Ill Adults Critical Illness | — | 2024-08-26 |
| Unknown | Pre-hospital ECMO or Conventional Resuscitation for Refractory Cardiac Arrest Out of Hospital Cardiac Arrest | N/A | 2024-03-01 |
| Recruiting | Indirect Calorimetry Guided Energy Provision in Critically Ill Patients With Obesity Critical Illness, Obesity | N/A | 2023-10-02 |
| Recruiting | Red Blood Cell Transfusion in ECMO - A Feasibility Trial Blood Loss Anemia, Extracorporeal Membrane Oxygenation Complication, Disability Physical | N/A | 2023-09-20 |
| Active Not Recruiting | SODium BICarbonate for Metabolic Acidosis in the ICU Metabolic Acidosis, Shock | Phase 3 | 2023-04-26 |
| Not Yet Recruiting | PRecision Ecmo in CardIogenic Shock Evaluation Cardiogenic Shock | — | 2023-04-03 |
| Recruiting | Trial of Venovenous ECMO to De-Sedate, Extubate and Mobilise in Hypoxic Respiratory Failure Mechanical Ventilation Complication, Hypoxemia, Acute Respiratory Distress Syndrome Due to COVID-19 | N/A | 2022-11-28 |
| Recruiting | Fibrinogen Early In Severe Trauma StudY II Trauma, Haemorrhagic Shock, Coagulopathy | Phase 3 | 2022-11-21 |
| Recruiting | PRECISION-TBI - An Observational Study of Patients With Moderate to Severe Traumatic Brain Injury Trauma, Brain | — | 2022-08-14 |
| Active Not Recruiting | Early Rehabilitation in Patients on Extracorporeal Membrane Oxygenation Extracorporeal Membrane Oxygenation Complication | N/A | 2022-04-27 |
| Unknown | Blender Biomarkers: A BLENDER Sub-study to Evaluate the Effect of Oxygen Dose on Oxidative Stress and Organ In Cardiac Failure, Critical Illness | — | 2022-04-18 |
| Active Not Recruiting | Australasian Resuscitation In Sepsis Evaluation: FLUid or Vasopressors In Emergency Department Sepsis Shock, Septic | Phase 3 | 2021-10-26 |
| Active Not Recruiting | The Cryopreserved vs. Liquid Platelets Trial Surgical Blood Loss, Hemorrhage | Phase 3 | 2021-08-17 |
| Recruiting | Bone Loss Prevention With Zoledronic Acid or Denosumab in Critically Ill Adults Critical Illness, Osteoporosis | Phase 2 | 2021-07-15 |
| Completed | INTENT-Muscle (A Sub-study of INTENT) Critically Ill | — | 2021-06-21 |
| Recruiting | Nutrition in Paediatric Critical Care ICU, Nutrition, Paediatric | — | 2021-06-07 |
| Completed | The REDEEM Pilot Study: A Feasibility RCT of Early ECMO in Severe Acute Respiratory Infection, Including COVID Mechanical Ventilation Complication, Severe Acute Respiratory Infection, Covid19 | N/A | 2021-03-01 |
| Recruiting | ErythroPOietin Alfa to Prevent Mortality and Reduce Severe Disability in Critically Ill TRAUMA Patients Trauma, Traumatic Injury, Traumatic Brain Injury | Phase 3 | 2020-11-09 |
| Completed | Recovery of Patients From COVID-19 After Critical Illness COVID-19, Critical Illness | — | 2020-07-01 |
| Enrolling By Invitation | The TEAM Long-Term Cohort Study (A Sub-study of TEAM(III)) Critically Ill, Mechanical Ventilation, Long Term Outcome | — | 2020-02-11 |
| Completed | Blend to Limit Oxygen in ECMO: A Randomised Controlled Registry Trial Cardiac Failure, Critical Illness | Phase 2 | 2019-09-18 |
| Recruiting | The EXCEL Registry of Patients Requiring ECMO Critically Ill, Acute Respiratory Failure, Acute Heart Failure | — | 2019-02-01 |
| Completed | Intensive Nutrition in Critically Ill Adults Critical Illness, Critically Ill | Phase 2 | 2018-10-15 |
| Completed | The Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock Trial Shock, Septic, Critically Ill, Vasoplegic Syndrome | Phase 2 | 2018-05-02 |
| Unknown | The Effect of Exercise Dosage on Physical Function, Cognition and Disability Following Critical Illness Critical Illness | — | 2018-03-09 |
| Completed | Treatment of Invasively Ventilated Adults With Early Activity and Mobilisation Critically Ill, Mechanically Ventilated | Phase 3 | 2018-02-28 |
| Completed | Extracorporeal Membrane Oxygenation Physical Training Critically Ill, Mechanically Ventilated, Extracorporeal Membrane Oxygenation Complication | N/A | 2018-02-19 |
| Unknown | Targeted Therapeutic Mild Hypercapnia After Resuscitated Cardiac Arrest Out-Of-Hospital Cardiac Arrest | N/A | 2018-02-15 |
| Completed | Long Term Effects of Erythropoietin in Patients With Moderate to Severe Traumatic Brain Injury Traumatic Brain Injury | — | 2017-08-01 |
| Completed | The PREDICT Study- a Registry in Critically Ill Patients to Determine Predictors of Disability Free Survival Critical Illness, Mechanical Ventilation Complication, Disabilities Multiple | — | 2017-07-18 |
| Completed | TARGET-Metabolic Effects Critical Illness, Enteral Nutrition | — | 2017-07-01 |
| Completed | The Augmented Versus Routine Approach to Giving Energy Trial Critical Illness | Phase 3 | 2016-06-16 |
| Recruiting | Short Period Incidence Study of Severe Acute Respiratory Illness Severe Acute Respiratory Infection | — | 2016-01-01 |
| Completed | Statistical Analysis Plan for an Individual Patient Data Meta-analysis of Three, International Trials Comparin Severe Sepsis and Septic Shock | — | 2015-01-01 |
| Completed | ICU Recovery in Australian Patients Intensive Care Unit Syndrome | — | 2014-08-01 |
| Completed | Supplemental Parenteral Nutrition in Critically Ill Adults: A Pilot Randomised Controlled Trial Multiple Organ Failure, Critical Illness | Phase 2 / Phase 3 | 2014-02-01 |
| Completed | Early Goal-Directed Sedation Compared With Standard Care in Mechanically Ventilated Critically Ill Patients Critical Illness and Mechanical Ventilation | Phase 3 | 2013-11-01 |
| Completed | TEAM: A Trial of Early Activity and Mobility in ICU Critically Ill | Phase 1 / Phase 2 | 2013-08-01 |
| Terminated | Open Lung Ventilation in ARDS: The PHARLAP Trial Acute Respiratory Distress Syndrome | N/A | 2012-10-01 |
| Completed | Standard Issue Transfusion Versus Fresher Red Blood Cell Use in Intensive Care- A Randomised Controlled Trial Transfusion, Age of Blood | Phase 3 | 2012-10-01 |
| Completed | TEAM: Trial of Early Activity and Mobilization Critically Ill Adults Ventilated >24 Hours in Intensive Care | — | 2012-07-01 |
| Completed | Nutrition Therapy in Adult Patients Requiring ECMO in Australia and New Zealand Patients on Extracorporeal Membrane Oxygenation | — | 2012-06-01 |
| Completed | Erythropoietin in Traumatic Brain Injury (EPO-TBI) Traumatic Brain Injury | Phase 3 | 2010-05-01 |
| Completed | The Prophylactic Hypothermia Trial to Lessen Traumatic Brain Injury Brain Injuries, Traumatic | N/A | 2010-04-01 |