NCT05295186

Non-invasive Respiratory Monitoring During SBT

Noninvasive Assessment of Respiratory Mechanics, Inspiratory Effort, and Respiratory Drive During Spontaneous Breathing Trial to Predict Extubation Failure in High-Risk Patients

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 238 (actual)
• Sponsor: University of Bari · Academic / Other
• Sex: All
• Age: 18 Years – 100 Years
• Healthy volunteers: Not accepted

Summary

Spontaneous breathing trials (SBTs) assess readiness for extubation, yet the use of conventional parameters used to establish weaning success may be elusive, especially in high-risk patients. Currently, non-invasive techniques allow comprehensive bedside assessment of advanced respiratory mechanics, including metrics of respiratory system compliance (CRS), respiratory muscle effort (POCC) and respiratory drive intensity (P0.1). This study investigates whether these measurements during SBT may improve the prediction of extubation outcomes

Conditions

• Mechanical Ventilation Complication
• Acute Respiratory Failure
• Re-intubation Rate

Timeline

• Start date: 2022-09-01
• Primary completion: 2024-04-01
• Completion: 2024-04-01
• First posted: 2022-03-25
• Last updated: 2025-03-05

Locations

2 sites across 1 country: Italy