| Not Yet Recruiting | Mechanical Insufflation-exsufflation and Hypertonic Saline in Nosocomial Bacterial Respiratory Tract Infection NCT06310941 | Hospital San Carlos, Madrid | N/A |
| Not Yet Recruiting | Nebulized Furosemide, Heparin, Hypertonic Saline in Mechanically Ventilated Acute Respiratory Distress Syndrom NCT07286409 | Tanta University | N/A |
| Not Yet Recruiting | Ventilator-based Inspiratory Muscle Training for Patients With Respiratory Failure NCT07353814 | Cairo University | N/A |
| Not Yet Recruiting | ClusterVAP: Multicentre Proteomic Endotyping of Ventilator-associated Pneumonia NCT07245888 | Region Skane | — |
| Recruiting | Targeting prEssure-Muscle-index to Avoid Ventilatory Over-Assistance During Pressure Support Ventilation NCT06921655 | Centre for Medical Sciences | N/A |
| Not Yet Recruiting | Effects of Mechanical Insufflation-Exsufflation With Optimized Settings on Wet Mucus Volume During Invasive Ve NCT06491017 | Hospital Clinic of Barcelona | N/A |
| Recruiting | EIT-guided PEEP Titration Versus Standard Ventilation in Bariatric Surgery NCT07207772 | Jianbo Wu | N/A |
| Recruiting | Prevalence of Pain in Mechanically Ventilated Patients in Intensive Care Units NCT07182851 | Centro Universitário Augusto Motta | — |
| Recruiting | VentilO Prospective Study NCT06826794 | Laval University | N/A |
| Recruiting | Sedation Efficacy and Safety of Remazolam Besylate in Ventilated Surgical Critically Ill Patients NCT06575530 | Beijing Shijitan Hospital, Capital Medical University | Phase 4 |
| Not Yet Recruiting | Lung Recruitment and PEEP Effects on Intracranial Pressure in Cranial Surgery NCT06771232 | University of Chile | — |
| Withdrawn | Flow Controlled Ventilation in Robot-assisted Laparoscopic Surgery NCT06256900 | Cantonal Hospital of St. Gallen | N/A |
| Completed | Maximum Inspiratory Pressure, Grip Strength and Physical Functional Status Relationship in MV Patients NCT06602050 | Saglik Bilimleri Universitesi | — |
| Completed | Ventilator Settings for Bronchoscopy During Mechanical Ventilation: a Randomized Controlled Study NCT06562725 | Centre Hospitalier Arras | N/A |
| Active Not Recruiting | TESTO-TRIAL: Use of Testosterone in Critically Ill Patients NCT06592144 | Leticia Maria Defendi Barboza Marson | Phase 4 |
| Completed | Nurse Education to Reduce Patient-Ventilator Asynchrony in the PICU NCT07273487 | Dr. Behcet Uz Children's Hospital | N/A |
| Recruiting | Early Diagnosis of ARDS in Mechanically Ventilated Patient Using LUS Score in Comparison With CT NCT06971042 | Tanta University | — |
| Recruiting | Effect of Implementing Evidence Based Practices on Prevention of Associated Nasal Pressure Injuries Among Pret NCT06642285 | Kafrelsheikh University | N/A |
| Recruiting | Behavioral Economic & Staffing Strategies in the ICU NCT06184945 | University of Nebraska | N/A |
| Not Yet Recruiting | Ultrasound Study of the Submentonian Musculature and Its Relationship in Dysphagia NCT06369337 | Universidad Europea de Madrid | — |
| Recruiting | Mechanical Ventilation on Hippocampus NCT06480162 | Beijing Sanbo Brain Hospital | — |
| Enrolling By Invitation | Optimizing the Assessment of Mechanical Ventilation by Integrating Advanced Monitoring Techniques [AVIM] NCT06236685 | Czech Technical University in Prague | N/A |
| Completed | Atelectasis Frequency in Different Ventilation Modes NCT06430229 | Ankara Etlik City Hospital | N/A |
| Recruiting | Efficacy of A Novel RinSe Device to Reduce Oral Bacteria in Intubated IntEnsive CaRe Patients: a Pilot Study NCT06193512 | The Cleveland Clinic | N/A |
| Completed | Preventing Failed Extubations NCT06301867 | Duke University | — |
| Terminated | Automatic Adjustment for Asynchronies During Mechanical Ventilation NCT06295237 | Hospital San Carlos, Madrid | N/A |
| Unknown | Individualized Selection of PEEP in Patients Affected by Expiratory Flow Limitation NCT06215001 | Università degli Studi di Ferrara | N/A |
| Recruiting | PCV-VG in Pediatric Laparoscopic Surgery NCT06245317 | Assiut University | N/A |
| Completed | pEEG Monitoring Effect on Delirium, Ventilator Days, and PICS NCT06019078 | Fraser Health | — |
| Recruiting | Current Practice of Ventilation Strategies in Children Undergoing General Anesthesia NCT06166706 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | — |
| Unknown | Efficacy and Safety of Automated Closed-loop Ventilator vs Conventional Open-loop Ventilator in the Emergency NCT06157073 | University of Malaya | N/A |
| Recruiting | Effect of Goal-directed Analgesia and Sedation Using EEG Derived QCON/qNOX in ICU Patients NCT06769308 | Università degli Studi di Ferrara | N/A |
| Recruiting | The Efficacy of P0.1-guided Sedation Protocol in Critically Ill Patients Receiving Invasive Mechanical Ventila NCT06203405 | Siriraj Hospital | N/A |
| Completed | Manual Hyperinflation and Physical Therapy Program on Lung Recruitment Mechanically Ventilated Pediatric Patie NCT06349785 | New Ismailia National University | N/A |
| Unknown | Evaluating the Performance of Invasive Ventilation During Specialized CPR NCT06175689 | University Hospital, Angers | — |
| Recruiting | Prone Positioning and Abdominal Binding on Lung and Muscle Protection in ARDS Patients During Spontaneous Brea NCT05826847 | University of Chile | N/A |
| Unknown | Volatile Sedation for Patients With the Acute Respiratory Distress Syndrome NCT06014138 | Guy's and St Thomas' NHS Foundation Trust | Phase 2 / Phase 3 |
| Completed | Comparison of Guiding Sedation Level by Respiratory Effort Versus Usual Care in Mechanically Ventilated Patien NCT06242236 | Ramathibodi Hospital | N/A |
| Completed | Mechanical Ventilator Weaning in Chronically Ventilated Patients NCT06976554 | University of California, Los Angeles | N/A |
| Completed | Potential Impact of the Use of the Application VentilO After Cardiac Surgery NCT05886413 | Laval University | — |
| Unknown | Adjunctive Esketamine for Analgesia in Mechanically Ventilated Septic Shock Patients NCT05839366 | Nanfang Hospital, Southern Medical University | Phase 3 |
| Completed | Reducing Oxygen Consumption in Critical Care NCT05796817 | Royal Brompton & Harefield NHS Foundation Trust | — |
| Active Not Recruiting | CT for Personalized Mechanical Ventilation NCT05977153 | Columbia University | N/A |
| Recruiting | The Effects of VC Versus PC Ventilation on Cerebral and Respiratory Parameters in Patients Undergoing Laparosc NCT06482983 | Umraniye Education and Research Hospital | N/A |
| Recruiting | Respiratory Muscle Structure and Function in Mechanically Ventilated Patients and Long-term Outcomes NCT05857774 | University Health Network, Toronto | — |
| Completed | Tracheal Suctioning With or Without Expiratory Pause Maneuver in Children NCT05805475 | Hospital de Clinicas de Porto Alegre | N/A |
| Unknown | Effect of Intraoperative PEEP Individualization According to Driving Pressure in Major Abdominal Surgery NCT05781373 | Mongi Slim Hospital | N/A |
| Unknown | Effect of End-inspiratory Airway Pressure Measurements on the Risk of VILI in Ventilated Patients NCT05991258 | University of Padova | — |
| Unknown | Mechanically Ventilated Children and Pacifiers NCT05566184 | Hitit University | N/A |
| Completed | Determination of Normal Values of Regional Pulmonary Strain Using a New Ultrasonographic Tool in Healthy Volun NCT04194346 | Centre hospitalier de l'Université de Montréal (CHUM) | N/A |
| Recruiting | Oxidative Lipidomic Biomarkers During Mechanical Ventilation in Critically Ill Patients (OXY-BAL). NCT05412810 | Ohio State University | — |
| Unknown | Evaluation of Regional Ventilation Distribution Using Electrical Impedance Tomography During Weaning From Mech NCT05726513 | Università degli Studi di Ferrara | N/A |
| Unknown | Automated Detection of Patient Ventilator Asynchrony Using Pes Signal NCT06186557 | Leiden University Medical Center | — |
| Completed | Translation and Validation of the Intensive Care Unit Mobility Scale (IMS) NCT05591950 | Charite University, Berlin, Germany | — |
| Completed | Vascular Injury in Mechanical Ventilation: a Proof-of-Concept Study NCT05538858 | University of Manitoba | — |
| Completed | Optimising Neonatal Ventilation with Closed-loop Oxygen Control NCT05657795 | King's College Hospital NHS Trust | N/A |
| Active Not Recruiting | Potential Impact of the Use of the Application VentilO NCT05587686 | Laval University | — |
| Unknown | Clinical Trial of Efficacy and Safety of Oral Drug in Adult Patients With COVID-19 NCT05365321 | Andrei Carvalho Sposito | Phase 1 / Phase 2 |
| Completed | Intraoperative Hypocapnia in PROVHILO and PROBESE NCT05550181 | NMC Specialty Hospital | — |
| Recruiting | Trial of Venovenous ECMO to De-Sedate, Extubate and Mobilise in Hypoxic Respiratory Failure NCT05562505 | Australian and New Zealand Intensive Care Research Centre | N/A |
| Completed | A Modified Cuff Leak Test and Reintubation in Mechanically Ventilated Patients NCT05550220 | Beijing Chao Yang Hospital | N/A |
| Completed | Pragmatic Randomized Trial for Arterial Catheters in the Critical Care Environment NCT05411315 | Dartmouth-Hitchcock Medical Center | N/A |
| Recruiting | Diaphragm Atrophy and Dysfunction in Mechanical Ventilation NCT05211661 | RWTH Aachen University | — |
| Completed | a Bayesian Analysis of Three Randomised Clinical Trials of Intraoperative Ventilation NCT05886387 | Instituto de Investigacion Sanitaria La Fe | — |
| Completed | Non-invasive Respiratory Monitoring During SBT NCT05295186 | University of Bari | — |
| Unknown | Systolic Function and Weaning-induced Pulmonary Edema (SystoWean Study) NCT05226247 | Centre Hospitalier Universitaire de Nice | N/A |
| Unknown | The Ultrasonographic Changes of Intercostal Muscles and Diaphragm in Mechanically Ventilated Preterm Neonates NCT05495763 | Noha Saied Ibrahim | — |
| Completed | PRactice of VENTilation in Patients With ARDS Due to COVID-19 vs Pneumonia NCT05650957 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | — |
| Recruiting | NMES Role to Prevent Respiratory Muscle Weakness in Critically Ill Patients and Its Association to Changes in NCT05536531 | Pontificia Universidad Catolica de Chile | N/A |
| Completed | Peppermint Aroma and Physiological Parameters NCT05541809 | Alexandria University | N/A |
| Completed | The Association Between the Extubation Process and Delirium in the Intensive Care Unit NCT07196813 | Eskisehir Osmangazi University | — |
| Unknown | Neural Pressure Support and Non-invasive Estimation of Transpulmonary Pressure in Spontaneous Ventilation Mode NCT05574829 | Fundación de Investigación Biomédica - Hospital Universitario de La Princesa | — |
| Unknown | The Cerebral-Respiratory Interaction During Spontaneous Breathing Ventilation in Neurosurgical Patients (CeRes NCT05363098 | Uppsala University | — |
| Unknown | The Cerebral-Respiratory Interaction in Controlled Mechanically Ventilated Neurosurgical Patients. (The CeRes- NCT05363085 | Uppsala University | — |
| Recruiting | The Caffeine Therapy in the Fetal to Neonatal Transition NCT05454332 | Hospital de Clinicas de Porto Alegre | Phase 4 |
| Unknown | Development of a Multimodal Index to Improve the Predictive Value of Success in Weaning From Mechanical Ventil NCT04554095 | Corporacion Parc Tauli | — |
| Completed | Comparison of the Acute Effects of Chest Physiotherapy Methods Applied in Different Positions in Preterm Newbo NCT05036603 | Sanko University | N/A |
| Completed | Evaluation of the Regeneration Capacity of Satellite Cells From the Quadriceps Compared to That of the Diaphra NCT05194631 | University Hospital, Montpellier | N/A |
| Unknown | Optimal High CPAP Pressures in Preterm Neonates Post-extubation NCT05230485 | McMaster Children's Hospital | N/A |
| Completed | Assessing Ventilator Safety in Patients on Pressure-Support Ventilation NCT05125952 | Duke University | N/A |
| Unknown | Extubation Failure in Critically Ill Cirrhotic Patients. NCT05244005 | University Hospital, Montpellier | — |
| Completed | A Problem Solving Intervention for Post-ICU Cognitive Impairment in Older Adults NCT03972384 | Ohio State University | N/A |
| Terminated | Electromagnetic Stimulation of the Phrenic Nerve in Critically Ill Mechanically Ventilated Patients (STIMIT-II NCT05238753 | Charite University, Berlin, Germany | N/A |
| Completed | The Effects of Early Mobilization and Endurance Training for Patients With Prolonged Mechanical Ventilator NCT05154786 | Taichung Tzu Chi Hospital | N/A |
| Withdrawn | Anakinra, COVID-19, Cytokine Storm NCT04603742 | Weill Medical College of Cornell University | Phase 2 |
| Withdrawn | Preoperative Inspiratory Muscle Training NCT04423614 | University of Florida | N/A |
| Unknown | Impact and Sequelae of High Ventilatory Drive in Critically Ill COVID-19 Patients NCT05363332 | Corporacion Parc Tauli | — |
| Completed | Metabolic Cost of IMT NCT05101850 | Royal Brompton & Harefield NHS Foundation Trust | — |
| Completed | Determining the Appropriate Setting of an Automated Secretion Removal Technology (TrachFlush) NCT05668299 | Hospitalsenheden Vest | N/A |
| Completed | Impact of Inspiratory Muscle Pressure Curves on the Ability of Professionals to Identify Patient-ventilator As NCT05144607 | Hospital Sirio-Libanes | N/A |
| Completed | Parental Perception of COVID-19 Vaccine in Technology Dependent Patients NCT05084976 | Northwell Health | — |
| Terminated | Automated Secretion Removal in ICU Patients NCT05056103 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | N/A |
| Recruiting | Optimising Ventilation in Preterms With Closed-loop Oxygen Control NCT05030337 | King's College Hospital NHS Trust | N/A |
| Unknown | The Effect of 6 ml/kg vs 10 ml/kg Tidal Volume on Diaphragm Dysfunction in Critically Mechanically Ventilated NCT05370248 | Dr Cipto Mangunkusumo General Hospital | N/A |
| Completed | Mechanical Power in Pediatric Mechanical Ventilation NCT05127317 | Bozok University | — |
| Unknown | Efficacy and Safety of Fentanyl for Pain Control in Newborn on Mechanical Ventilation NCT04937946 | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | Phase 4 |
| Unknown | Diastolic dYsfunctioN AssessMent in critICally Ill Patients NCT04584203 | Humanitas Clinical and Research Center | — |
| Recruiting | How Early Mobilization Impacts on Diaphragm Thickness in Critically Ill Children NCT04534296 | Children's Hospital of Fudan University | N/A |
| Unknown | Effects of NIV and CPAP on Ventilation Distribution, Measured by EIT, During Deep Sedation in Paediatric Patie NCT05495477 | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | N/A |
| Unknown | Registry of Hospitalized Patients in University Hospital Dubrava Respiratory Center NCT05151094 | University Hospital Dubrava | — |
| Completed | The REDEEM Pilot Study: A Feasibility RCT of Early ECMO in Severe Acute Respiratory Infection, Including COVID NCT04708457 | Australian and New Zealand Intensive Care Research Centre | N/A |
| Completed | The Effectiveness of the Use of Oxygen Reserve Index in Preventing Hyperoxia in the Intensive Care Unit. NCT05807815 | Tepecik Training and Research Hospital | N/A |
| Unknown | Effects of NMES in Critically Ill Patients NCT04382378 | Escola Superior de Ciencias da Saude | N/A |
| Completed | Mechanical Ventilation-Associated Complications and Co-Morbidities in Children Admitted in Pediatric Intensive NCT06368973 | Benha University | — |
| Completed | How To Prevent Ventilator-Related Lung Damage in Intraoperative Mechanical Ventilation? Pcv or Vcv ? NCT05814081 | Başakşehir Çam & Sakura City Hospital | — |
| Completed | Comparing Two Different Modes of Ventilation in Pretem Neonates Bilevel VG and PRVC NCT04191239 | Ankara City Hospital Bilkent | — |
| Completed | Effect of Lung Volume Recruitment Technique After Extubation NCT05128552 | Cairo University | N/A |
| Completed | Respiratory Drive and Inspiratory Effort in COVID-19 Associated ARDS NCT06224010 | University of Turin, Italy | — |
| Completed | Patient-ventilator Interaction During NIV With Helmet: a Comparison Between PSV and the New NIV NPS Software NCT06004206 | ASL Novara | N/A |
| Completed | Efficacy of CONvalescent Plasma in Patients With COVID-19 Treated With Mechanical Ventilation NCT04558476 | University of Liege | Phase 2 |
| Completed | Prone Position Improves End-Expiratory Lung Volumes in COVID-19 Acute Respiratory Distress Syndrome NCT04818164 | Istanbul University - Cerrahpasa | — |
| Completed | Measuring Thickness of the Normal Diaphragm in Children Via Ultrasound. NCT04589910 | Erasmus Medical Center | N/A |
| Completed | Left Ventricular Diastolic Dysfunction as a Predictor of Weaning Failure From Mechanical Ventilation NCT04703387 | Tanta University | — |
| Terminated | Awake Prone Positioning to Reduce Invasive VEntilation in COVID-19 Induced Acute Respiratory failurE NCT04347941 | University College Hospital Galway | N/A |
| Completed | INTELLiVENT-ASV Using Mainstream Versus Sidestream End-Tidal CO2 Monitoring NCT04599491 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | N/A |
| Completed | Gastric Ultrasound to Monitor Gastric Residual Volume NCT04119089 | Hospices Civils de Lyon | — |
| Completed | Ventilator-induced Lung Injury Vortex in Patients With SARS-CoV-2 NCT04174313 | Hospital El Cruce | — |
| Completed | Early Identification and Prevention of Extubation Failure in Adults Using Integrated Pulmonary Index NCT04231890 | Rush University Medical Center | N/A |
| Completed | Characterization of Reverse Triggering and Other Asynchronies in COVID-19 Patients Under Invasive Mechanical V NCT04448782 | Corporacion Parc Tauli | — |
| Completed | Incidence, Risk Factors and Outcomes of Diaphragm Dysfunction After Lung Transplantation NCT04103996 | University Health Network, Toronto | — |
| Completed | Ketamine Infusion as Sedative Analgesic in Severe ARDS NCT04818827 | Interfaith Medical Center | — |
| Withdrawn | Determinants of Implementation Success Coordinating Ventilator, Early Ambulation and Rehabilitation Efforts NCT04249141 | Ohio State University | — |
| Completed | Lung-protective Mechanical Ventilation for Abdominal Laparoscopic Surgeries NCT04546932 | Vietnam Military Medical University | N/A |
| Unknown | Semirecumbent Position by Mechanical Ventilation NCT04149665 | Bürgerspital Solothurn | — |
| Completed | Efficacy and Safety of the DYNAtraq Device to Prevent Complications in Tracheostomy in Mechanically Ventilated NCT04668742 | Fundación Cardiovascular de Colombia | N/A |
| Unknown | Cross-sectional, Observational, Prospective and Analytical Study:MECHANICAL POWER DAY (MPDay) NCT03936231 | Hospital Universitario Marqués de Valdecilla | — |
| Unknown | Smartphone Application for Initiation of Protective Ventilation. Clinical Impact of Instrumental Dead Space Re NCT04390360 | Laval University | N/A |
| Completed | Evaluation of the CleanSweep™ Closed Suction System on Length of Mechanical Ventilation and Ventilator-Associa NCT03868735 | Rush University Medical Center | N/A |
| Completed | Ultrasound for Assessment of Extubation Readiness NCT04957264 | Mount Sinai Hospital, Canada | — |
| Completed | Tongue Edema Caused by Intubation Tube in Intensive Care Unit Patients NCT05249738 | Selcuk University | — |
| Completed | Lowering PEEP: Weaning From High PEEP Setting NCT04429399 | University of Bari | N/A |
| Completed | LPP , MP and DP:Relation With Mortality and SOFA in Mechanically Ventilated Patients in ER, Ward and ICU NCT04193254 | JOSE IVAN RODRIGUEZ DE MOLINA SERRANO | — |
| Completed | Deventilation Dyspnea in COPD Patients Using NIV NCT03503123 | University Medical Center Groningen | — |
| Unknown | Delirium, Agitation/Sedation, Pain and Dyspnea in Respiratory Intensive Care Unit (NIVILIUM) NCT03880084 | University of Modena and Reggio Emilia | — |
| Completed | Rehabilitation Program for Weaning From Mechanical Ventilator NCT04021615 | Sherin Hassan Mohammed Mehani | N/A |
| Terminated | DOSE Trial of Opioid Sparing Effect NCT03938857 | Duke University | Phase 1 |
| Terminated | Open Lung Strategy, Gas Distribution and Right Heart Function in ARDS Patients NCT03202641 | Massachusetts General Hospital | N/A |
| Suspended | Diaphragm Ultrasound as a Powerful Tool in Managing Acute Hypoxemic Respiratory Failure in Hematological Patie NCT04026217 | Azienda Sanitaria-Universitaria Integrata di Udine | — |
| Completed | Effects of Endotracheal Tube Cuff Pressure Control on Microaspiration of Gastric Contents NCT04061083 | Afyonkarahisar Health Sciences University | N/A |
| Completed | Oral Care of Intubated Intensive Care Patient NCT06258603 | Nigde Omer Halisdemir University | N/A |
| Completed | BIPAP in the Management of Acute Respiratory Distress Syndrome NCT05483959 | South Valley University | N/A |
| Terminated | Comparison of Two Extubation Techniques in Critically Ill Adult Patients NCT03918811 | Hospital Donación Francisco Santojanni | N/A |
| Unknown | Nebulized hypErtonic Saline for Better Prevention of mUcus pLug in Critical Adult Tracheostomized Patients NCT03870646 | Hospital Universitario Virgen de la Arrixaca | Phase 3 |
| Recruiting | Diaphragm Structure and Pathobiology in Patients Being Bridged to Lung Transplant NCT03667027 | University Health Network, Toronto | — |
| Completed | A New Ultrasonographic Tool to Assess Pulmonary Strain in Patients Under One-lung Ventilation. NCT03817918 | Centre hospitalier de l'Université de Montréal (CHUM) | N/A |
| Unknown | Effect of Three Modalities of Spontaneous Breathing Tests on Respiratory Efforts in Tracheostomized Patients NCT03856424 | Piquilloud Imboden Lise | N/A |
| Recruiting | Volume Support/Assist Control Mode Ventilation and Diaphragmatic Atrophy NCT03901924 | University of Chicago | N/A |
| Completed | Post-extubation Assessment of Laryngeal Symptoms and Severity NCT03726086 | Johns Hopkins University | — |
| Completed | Communication Strategies for Mechanically Ventilated Patients in Intensive Care Units NCT05651984 | University of Liege | N/A |
| Completed | Lung and Diaphragm-Protective Ventilation by Means of Assessing Respiratory Work NCT03612583 | University Health Network, Toronto | Phase 1 |
| Unknown | Ventilator Induced Diaphragm Dysfunction in Pediatric Critically Ill Patients (VIDD) NCT03768232 | Bambino Gesù Hospital and Research Institute | — |
| Completed | Effect of PEEP on Lung Regional Ventilation and Perfusion NCT04081155 | Yun Long | — |
| Completed | National Approach to Standardize and Improve Mechanical Ventilation NCT03790150 | King Abdullah International Medical Research Center | — |
| Completed | Re-Evaluation of the Effects of High PEEP During General Anesthesia For Surgery (REPEAT) NCT03937375 | Hospital Israelita Albert Einstein | — |
| Completed | Evaluation of V/Q Mismatch as Predictor of Pulmonary Postoperative Complications in Patients Undergoing Major NCT05454917 | Università degli Studi di Ferrara | — |
| Unknown | A Non-invasive Evaluation of Kidney-Lung Interactions NCT03747731 | St. Bortolo Hospital | — |
| Unknown | Randomized Study Evaluating the Efficacy of Low Intensity Transcranial Electrical Stimulation (Tdcs) for the R NCT03640455 | Assistance Publique - Hôpitaux de Paris | Phase 2 |
| Unknown | Driving Pressure Variation: NAVA vs PSV NCT03719365 | Azienda Ospedaliero Universitaria Maggiore della Carita | N/A |
| Completed | Reiki Intervention for Seriously Ill Elders Intensive Care Unit (RISE-ICU) NCT03685760 | Ohio State University | N/A |
| Unknown | Weaning Algorithm for Mechanical VEntilation NCT03697785 | Royal Brompton & Harefield NHS Foundation Trust | N/A |
| Unknown | Mechanical Ventilation During Cardiopulmonary Bypass NCT03629574 | Azienda Ospedaliera di Padova | N/A |
| Terminated | Entrainment-Based Mechanical Ventilation NCT03512067 | Brigham and Women's Hospital | N/A |
| Unknown | Effect of Position and Pneumoperitoneum on Respiratory Mechanics and Transpulmonary Pressure During Laparoscop NCT03526003 | Rambam Health Care Campus | — |
| Recruiting | A New Ultrasonographic Tool to Assess Pulmonary Strain in the ICU NCT03405779 | Centre hospitalier de l'Université de Montréal (CHUM) | — |
| Completed | Effects of Growth Hormone on Difficult Ventilator Weaning Patients NCT03717168 | National Cancer Institute, Egypt | Phase 2 |
| Completed | Effect of Diaphragm Stimulation During Surgery NCT03303040 | University of Florida | N/A |
| Terminated | Antimicrobial Treatment in Patients With Ventilator-associated Tracheobronchitis NCT03012360 | University Hospital, Lille | Phase 4 |
| Unknown | Heartrate Variability During Conventional and Variable Pressure Support Mechanical Ventilation NCT03360968 | Medical University of Vienna | N/A |
| Completed | Rapid Pathogen Identification in Ventilated Patients With Pneumonia NCT03996330 | Cambridge University Hospitals NHS Foundation Trust | — |
| Completed | Efficacy of the "Start to Move" Protocol on Functionality, Delirium and Acquired Weakness in ICU NCT05053724 | Hospital Felix Bulnes | N/A |
| Completed | Transpulmonary Pressures in Mechanical Ventilated Patients With Morbid Obesity NCT02309190 | The University of Texas Health Science Center, Houston | — |
| Completed | Cognitive Behavioral Therapy for Mechanical Ventilation Wean NCT04763590 | University of Pennsylvania | N/A |
| Completed | Impacts of Low-Dose Dexmedetomidine on Sleep Quality in Mechanically Ventilated ICU Patients NCT03335527 | Peking University First Hospital | Phase 4 |
| Unknown | Measuring Heart and Lung Function in Critical Care NCT03424798 | University of Oxford | — |
| Completed | Protocolized Post-Extubation Respiratory Support Study NCT03288311 | Vanderbilt University Medical Center | N/A |
| Unknown | Non Invasive Mechanical Ventilation VERSUS Oxygen MASK NCT03259854 | Assiut University | N/A |
| Completed | NIV Versus HFO Versus Standard Therapy Immediately After Weaning From Mechanical Ventilation in ARDS Patients NCT06332768 | Northern State Medical University | N/A |
| Unknown | Assisted or Controlled Ventilation in Ards (Ascovent) NCT03245684 | University of Roma La Sapienza | N/A |
| Suspended | Low-dose Dexmedetomidine in Mechanically Ventilated ICU Patients NCT03172897 | Peking University First Hospital | Phase 4 |
| Completed | Effect of Recruitment Maneuvers Plus Optimal PEEP Versus Optimal PEEP Alone in One Lung Ventilation NCT03635281 | Università degli Studi di Ferrara | N/A |
| Completed | A New Ultrasonographic Tool to Assess Regional Pulmonary Strain NCT03092557 | Centre hospitalier de l'Université de Montréal (CHUM) | N/A |
| Completed | The PREDICT Study- a Registry in Critically Ill Patients to Determine Predictors of Disability Free Survival NCT03226912 | Australian and New Zealand Intensive Care Research Centre | — |
| Completed | Effect of Sedation Strategy on Duration Mechanical Ventilation in Patient After Cardiac Surgery NCT05451121 | Anesthesia Research Group UA | N/A |
| Unknown | Specific Small RNA in Plasma for Predicting Diaphragm Dysfunction in Mechanically Ventilated Patients NCT03172169 | Southeast University, China | — |
| Completed | Endotracheal Tube Securement Study NCT03760510 | Vanderbilt University Medical Center | N/A |
| Completed | Cycling Exercise in Mechanical Ventilation NCT03581760 | University Hospital Ostrava | N/A |
| Completed | Thoracic Fluid Content in Prediction of Failure of Weaning From Mechanical Ventilation NCT03094390 | Cairo University | — |
| Unknown | NMES to Prevent Respiratory Muscle Atrophy in Mechanically Ventilated Patients NCT03453944 | University Medical Center Nijmegen | N/A |
| Completed | Continuous Endotracheal Cuff Pressure Control to Prevent Ventilator Associated Respiratory Infections NCT02966392 | Oxford University Clinical Research Unit, Vietnam | N/A |
| Completed | Effects of Positive End-expiratory Pressure on Intracranial Pressure in Patients With Severe Traumatic Brain I NCT03296293 | Hongpeng Li | N/A |
| Unknown | Effect of the Intra-abdominal Pressure on the Risk of Delirium in Mechanically Ventilated Patients. NCT03218358 | Assiut University | — |
| Unknown | Does UROSHIELD® Influence Bacterial Growth On Endotracheal Tubes NCT02074306 | Shaare Zedek Medical Center | N/A |
| Completed | Hand Grip Strength and Medical Research Council Scale as Predictors of Weaning Failure NCT03991702 | Hospital de Clinicas de Porto Alegre | — |
| Completed | Endotracheal Tube Audible Leak Test NCT02461017 | University of Mississippi Medical Center | — |
| Completed | The Validity of Maximal Diaphragm Thickening Fraction to Measure Diaphragm Function in Mechanically Ventilated NCT03129217 | University Health Network, Toronto | — |
| Completed | Intravenous Clonidine for Sedation in Infants and Children Who Are Mechanically Ventilated - Dosing Finding St NCT02249039 | Johns Hopkins University | Phase 1 |
| Completed | Clinical Study of the Endotracheal Tube Used in Prone Position Ventilation Condition NCT02449356 | Wangyuan Zou | N/A |
| Completed | Perioperative Mechanical Ventilation and Postoperative Monitoring of IPI NCT02524522 | Northern State Medical University | N/A |
| Terminated | PReventing the EffectS of Intubation on DEglutition NCT02442102 | Johns Hopkins University | N/A |
| Completed | Protective Mechanical Ventilation and Risk of Postoperative Complications in Abdominal Surgery NCT03165760 | Mongi Slim Hospital | N/A |
| Completed | Lung Impedetiometric Modification in SBT and Extubation Failure NCT03894332 | University Magna Graecia | — |
| Unknown | Efficacity and Safety of Mechanical Insufflation-exsufflation on ICU NCT03316079 | University Hospital, Bordeaux | N/A |
| Completed | Use of Bispectral Index Monitoring to Detect Deep Sedation in Mechanically Ventilated Patients: Validity Study NCT02439840 | Capital Medical University | — |
| Completed | Bacterial Colonization in Tracheostomized Patients With Neurological or Neuromuscular Disease NCT02400086 | Centre d'Investigation Clinique et Technologique 805 | — |
| Terminated | Change In Diaphragmatic Thickness Predicts Extubation Success NCT02656199 | Albert Einstein Healthcare Network | — |
| Completed | Effects on Respiratory Mechanics of Two Different Ventilation Strategies During Robotic-Gynecological Surgery NCT03335449 | SPINAZZOLA GIORGIA | N/A |
| Completed | BIS Monitoring to Detect Deep Sedation NCT02203344 | Capital Medical University | — |
| Completed | Effect of Anesthetics on Oxygenation and Microcirculation During One-lung Ventilation NCT02191371 | Seoul National University Hospital | N/A |
| Unknown | Sequential Use of Propofol/Midazolam and Dexmedetomidine for Sedation in Mechenical Ventialtion Patients in IC NCT02122055 | Tianjin Third Central Hospital | Phase 4 |
| Completed | Impact of Tracheal Cuff Shape on Microaspiration in Intensive Care Units NCT01948635 | University Hospital, Lille | N/A |
| Unknown | Effectiveness of Reanimator Muller in Patients With Chest Tube NCT02472041 | University of Campinas, Brazil | Phase 2 / Phase 3 |
| Unknown | The Effect of Ulinastatin on Bronchoalveolar Lavage Fluid of Inflammatory Factors in Patients With Ventilator- NCT01865266 | Shanghai Minhang Central Hospital | Phase 2 / Phase 3 |
| Unknown | Efficacy of Oxepa Enteral Feeding in LTAC (Long Term Acute Care Hospital) Patients on Chronic Ventilation- a P NCT02208700 | Grace Hospital, Cleveland, Ohio | N/A |
| Unknown | Evaluation of the Effects of Fluid Therapy on Respiratory Mechanics NCT02071524 | Università degli Studi di Ferrara | N/A |
| Completed | Diaphragm Injury and Dysfunction During Mechanical Ventilation NCT03108118 | University Health Network, Toronto | — |
| Completed | New Setting of Neurally Adjusted Ventilatory Assist During Mask Noninvasive Ventilation NCT03041402 | Southeast University, China | N/A |
| Completed | Using Ultrasound to Study Respiratory Muscle Function in Critically Ill Patients NCT03139695 | Wake Forest University Health Sciences | — |
| Completed | Airway Management in Thoracic Anesthesia in Italy NCT02361983 | Azienda Ospedaliera S. Maria della Misericordia | — |
| Completed | Nasal Mask Ventilation During the Induction of General Anesthesia NCT01651286 | Massachusetts General Hospital | N/A |
| Completed | The Effect of Recruitment Maneuver With Protective Ventilation During Thoracic Surgery NCT01630395 | Seoul National University Hospital | N/A |
| Completed | Characteristics of Lower Respiratory Tract Escherichia Coli Isolates in Mechanically Ventilated Intensive Care NCT03303937 | Hôpital Louis Mourier | — |
| Unknown | Study of Variables Related to the Discontinuation of Mechanical Ventilation in Patients With Head Injury NCT01713010 | Federal University of Uberlandia | — |
| Unknown | Enteral Versus Intravenous Sedation in Critically Ill High-risk ICU Patients NCT01360346 | University of Milan | Phase 3 |
| Completed | Sedation Optimisation Strategy (S.O.S.) Ventilation NCT01486121 | University Hospital, Montpellier | Phase 3 |
| Unknown | TICACOS International NCT01479673 | Rabin Medical Center | N/A |
| Terminated | Effect of Intermittent Versus Continuous Subglottic Secretion Drainage on Tracheal Mucosa Damages NCT01555229 | Rennes University Hospital | Phase 3 |
| Completed | A Pilot Clinical Trial to Evaluate the Effects of Acupuncture in Patients on Prolonged Mechanical Ventilation NCT01621139 | Mayo Clinic | Phase 1 / Phase 2 |
| Completed | Asynchronies During Mechanical Ventilation NCT03451461 | Corporacion Parc Tauli | — |
| Completed | Reduce Pediatric Sedation to Reduce Mechanical Ventilation Complication in ICU NCT02040168 | Nantes University Hospital | — |
| Completed | Prevention Inhalation of Bacterial by Using Endotracheal Tube Balloon Polyvinyl Chloride or Polyurethane NCT01114022 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | Patient-ventilator Asynchrony During Mechanical Non-Invasive Assisted-ventilation in Pediatric Patients (NavPe NCT01238757 | University Hospital, Geneva | N/A |
| Completed | Effects of a Complete Diet in Critically Ill Patients With Stress Hyperglycemia NCT01233726 | Vegenat, S.A. | N/A |
| Completed | Continuous Control of Polyurethane Tracheal-cuff Pressure: Efficiency of a Pneumatic Device NCT01351259 | University Hospital, Lille | Phase 4 |
| Unknown | Application of Neurally Adjusted Ventilatory Assist to Children After Congenital Cardiac Surgery NCT01662011 | Shanghai Jiao Tong University School of Medicine | Phase 3 |
| Completed | Assessing Gas Exchange in Intensive Care Patients on a Ventilator NCT02599350 | University of Aberdeen | — |
| Completed | Strategies To Prevent Pneumonia 2 (SToPP2) NCT00893763 | University of South Florida | Phase 2 |