NCT01662011

Application of Neurally Adjusted Ventilatory Assist to Children After Congenital Cardiac Surgery

Application of Neurally Adjusted Ventilatory Assist to Children After Congenital Cardiac Surgery: the Effect of Patient-ventilator Interaction, Gas Exchange and Hemodynamics

• Status: Unknown
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 72 (estimated)
• Sponsor: Shanghai Jiao Tong University School of Medicine · Academic / Other
• Sex: All
• Age: 7 Days – 18 Years
• Healthy volunteers: Not accepted

Summary

Neurally adjusted ventilatory assist (NAVA) is a new mode of mechanical ventilation that delivers ventilatory assist in proportion to neural effort. It was a controlled randomized single-center prospective study in order to explore the efficacy of this new mode of mechanical ventilation after corrective open-heart surgery for congenital heart disease.

Detailed description

1. To evaluate the effect of the patient-ventilator interaction in children underwent open-heart surgery when ventilated with NAVA, compared with conventional mechanical ventilation. 2. To verify the benefits of NAVA in improving the gas exchange and hemodynamics after biventricle repair for CHD.

Conditions

• Mechanical Ventilation Complication
• Congenital Heart Disease

Interventions

Type	Name	Description
DEVICE	mode of neurally adjusted ventilatory assist	patients ventilated with the mode of neurally adjusted ventilatory assist after corrective open-heart surgery
DEVICE	Mode of pressure support ventilation	Patients ventilated with the mode of pressure support ventilation after corrective open-heart surgery

Timeline

• Start date: 2010-01-01
• Primary completion: 2011-12-01
• Completion: 2012-12-01
• First posted: 2012-08-10
• Last updated: 2012-08-10

Locations

1 site across 1 country: China