| Not Yet Recruiting | Influence of Lung Volume Optimization Maneuver on Cardiac Output and Lung Compliance in Ventilated Children Wi NCT07486167 | Charite University, Berlin, Germany | Phase 1 / Phase 2 |
| Not Yet Recruiting | LLM-Based Intelligent Health Management Assistant in Life-Cycle Health Management of Cardiac Surgery Patients NCT07521488 | Beijing Anzhen Hospital | N/A |
| Not Yet Recruiting | Chest X-Rays for Early Detection of Congenital Heart Disease in Newborns NCT07520149 | Assiut University | — |
| Not Yet Recruiting | Autus Valve Continued Access Study (CAS) NCT07466745 | Autus Valve Technologies, Inc. | N/A |
| Not Yet Recruiting | Comparison of the Best Method for Measuring Anti-Xa Activity in Children Receiving Unfractionated Heparin in C NCT07365670 | Centre Hospitalier Universitaire de la Réunion | N/A |
| Not Yet Recruiting | Perioperative Lidocaine for Lung Protection in Infants Undergoing Cardiac Surgery NCT07499154 | The Children's Hospital of Zhejiang University School of Medicine | Phase 4 |
| Not Yet Recruiting | Longitudinal Validation of CIRC Technologies NCT07081711 | The Cleveland Clinic | — |
| Not Yet Recruiting | Design and Application of a Home Care WeChat Mini-Program for Children After Congenital Heart Disease Surgery NCT07385209 | ruijie YangLan | N/A |
| Recruiting | Non-Invasive Electrocardiographic Imaging for Personalized Arrhythmia Care in Congenital Heart Disease NCT07425132 | Fundacion para la Innovacion en Biomedicina (FIBMED) | — |
| Withdrawn | A Study of Pregnancy Outcomes in Congenital Heart Disease NCT06678256 | Mayo Clinic | — |
| Not Yet Recruiting | Using Near-Infrared Spectroscopy Devices to Assess Myocardial and Visceral Perfusion During Complex Congenital NCT07361523 | Boston Children's Hospital | — |
| Not Yet Recruiting | Assessment of Psychiatric Problems in Pre- and Post-Intervention in Patients With CHD NCT07326384 | Assiut University | — |
| Not Yet Recruiting | Congenital Heart Diseases and Developmental Assessment in Cholestatic Infants Under Two Years NCT07247604 | Assiut University | — |
| Recruiting | Influence of Personalized Lung Volume Optimization Maneuver on Lung Function and Cardiac Performance in Childr NCT07193719 | Charite University, Berlin, Germany | Phase 1 / Phase 2 |
| Recruiting | Starlight Cardiovascular Lifeline Ductus Arteriosus Stent IDE Study NCT07114718 | Starlight Cardiovascular Inc | N/A |
| Not Yet Recruiting | Calprotectin and Gut Disease Study NCT07112794 | Great Ormond Street Hospital for Children NHS Foundation Trust | — |
| Recruiting | Parent Navigator Program (PNP) to Improve Outcomes in Latino/x Children and Parents NCT07023367 | Children's Hospital Los Angeles | N/A |
| Not Yet Recruiting | Effectiveness of High-Energy Density Enteral Nutrition for Enhancing Physical Growth and Cognitive Brain Devel NCT07115108 | Children's Hospital of Fudan University | N/A |
| Not Yet Recruiting | Prevalence of Liver Dysfunction in Pediatric Patients With Congenital Heart Disease at Assiut. NCT07144501 | Assiut University | N/A |
| Recruiting | Propranolol Treatment for Postoperative Chylothorax NCT06833320 | June Wu | Phase 1 / Phase 2 |
| Recruiting | Psychological Trauma, Post-Traumatic Stress Disorder, and Resilience in Adults With Congenital Heart Disease NCT06952933 | Dartmouth-Hitchcock Medical Center | — |
| Active Not Recruiting | Pediatric Adhesion and New Dermal Approach Study NCT07118124 | iRhythm Technologies, Inc. | N/A |
| Not Yet Recruiting | Empiric Pulsed Field Pulmonary Vein Isolation During Atrial Tachycardia Ablation in Adults With Congenital Hea NCT06969378 | Boston Children's Hospital | N/A |
| Recruiting | Prenatal Maternal Mental Health and Neurodevelopment in Congenital Heart Disease NCT06711666 | Institut National de la Santé Et de la Recherche Médicale, France | — |
| Recruiting | Fontan Fitness Trial NCT06918795 | Children's Hospital of Philadelphia | N/A |
| Not Yet Recruiting | Study of Exercise Capacity and Physical Activity in Children With Congenital Heart Disease NCT06945003 | University of Ulster | N/A |
| Recruiting | Sodium-Glucose Cotransporter 2 Inhibitors for Repaired Tetralogy of Fallot Patients for Enhancement of Cardio- NCT06668389 | The University of Hong Kong | Phase 4 |
| Not Yet Recruiting | SGLT2 Inhibition With Empagliflozin in Fontan Circulatory Failure NCT06955260 | Subodh Verma | Phase 3 |
| Completed | Comparison of Two Gait Re-training Modalities During a Cardiac Rehabilitation Stay: Benefit of Orienteering Wa NCT06941597 | Fondation Ildys | — |
| Enrolling By Invitation | Precision Medicine in the CICU: Identifying Proteomic Biomarkers NCT06642662 | Boston Children's Hospital | — |
| Recruiting | Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp System NCT06080074 | Stanford University | Phase 2 |
| Recruiting | Antenatal Investigation of Fetuses With Complex Congenital Heart Defects Using multiOMICS NCT06705543 | University Hospital, Bordeaux | N/A |
| Active Not Recruiting | The Influence of Probiotics on Metabolome and Heart Rate Variability in Heart Failure of Structure Heart Disea NCT06872320 | Chang Gung Memorial Hospital | N/A |
| Recruiting | HFNC vs NIPPV Following Extubation NCT05869825 | Emory University | N/A |
| Recruiting | A Study of Hemodynamic Cardiopulmonary Exercise for CHD NCT06566196 | Mayo Clinic | N/A |
| Recruiting | Effect of Sacubitril-Valsartan on Cardiac Structure and Function NCT06693674 | Mayo Clinic | Phase 3 |
| Recruiting | Wearable Assessment of Thoracic, Cardiac Health and Exercise Performance Trial NCT06671171 | The University of Hong Kong | — |
| Recruiting | A Chinese Multicenter Study on Surgical Techniques and Outcomes Across the Lifespan in Congenital Heart Diseas NCT07524998 | China National Center for Cardiovascular Diseases | — |
| Recruiting | Remote Monitoring in Pregnant Women With Congenital Heart Disease Using Wrist Wearables NCT06818760 | The Cleveland Clinic | — |
| Completed | Bilateral Two Levels Serratus Anterior Plane Block in Pediatric Cardiac Surgery With Median Sternotomy NCT06221150 | Cairo University | N/A |
| Recruiting | Exercise MRI to Evaluate Cardiorespiratory Fitness in Children With Heart Disease NCT06325280 | University of Alberta | — |
| Recruiting | High Intensity Interval Training in Patients With a Right Ventricle to Pulmonary Artery Conduit NCT06771687 | Erasmus Medical Center | N/A |
| Not Yet Recruiting | Value of MRI in Congenital Heart Disease NCT06752187 | Assiut University | — |
| Not Yet Recruiting | The Efficacy of Systematic Oral Feeding Education Program NCT06763497 | National Taiwan University Hospital | N/A |
| Recruiting | PDA for Kidneys Study NCT06658496 | University of Wisconsin, Madison | — |
| Active Not Recruiting | Application of a Clinical Decision Support System to Reduce Mechanical Ventilation Duration After Cardiac Surg NCT05687292 | Boston Children's Hospital | — |
| Not Yet Recruiting | Pregnancy in GUCH Patients NCT06574386 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | N/A |
| Recruiting | Extracellular Vesicle Micro RNA Profiling in Congenital Heart Disease: Fetal-Maternal Regulation in Neonatal T NCT06434207 | Boston Children's Hospital | — |
| Recruiting | Skin Pigment/Pulse Oximeter in Congenital Heart Disease (CHD) NCT06575270 | Icahn School of Medicine at Mount Sinai | — |
| Recruiting | NeoDoppler: New Ultrasound Technology for Continuous Monitoring of Cerebral Circulation Pilot NCT06646250 | St. Olavs Hospital | — |
| Recruiting | Digital Health Promotion for Children With Congenital Heart Disease and Their Guardians NCT06626672 | Deutsches Herzzentrum Muenchen | N/A |
| Recruiting | Improving Congenital Heart Disease Care NCT06581484 | University of California, San Francisco | N/A |
| Not Yet Recruiting | Research on Body Voice AI Recognition System for Children's Health Management NCT06542120 | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | — |
| Not Yet Recruiting | Tailored MgSO4 Supplementation to Reduce Complications in Pediatric Heart Surgery NCT06564376 | West Virginia University | N/A |
| Completed | RAPID: a Comparison Study of a Novel Ultrasound Device of Automated Congenital Heart Imaging NCT06281639 | University of Minnesota | — |
| Completed | Development and Polit Study of Get Ready With my Heart Program NCT06418373 | Children's Hospital of Fudan University | N/A |
| Active Not Recruiting | An Observational Study to Learn More About How Safe Rivaroxaban is And How Well it Works in Children With Cong NCT06193863 | Bayer | — |
| Not Yet Recruiting | IntelliStent for Pulmonary Flow Adjustment in Congenital Heart Disease and Dilated Cardiomyopathy NCT06072937 | HeartPoint Global | N/A |
| Recruiting | Neuro-cardiac Rehabilitation in Youth With Congenital Heart Disease (QUALINEUROREHAB) NCT05670132 | University Hospital, Bordeaux | N/A |
| Completed | Fetal Heart Ultrasound Suspicious Radiographic Finding Identification - Reader Study NCT06392555 | BrightHeart | — |
| Not Yet Recruiting | Procedural Pain Management by Multimodal Sedation Analgesia Combining Hypnosis in Children With Congenital Hea NCT06373627 | Fondation Hôpital Saint-Joseph | N/A |
| Recruiting | Learning by Heart: The Effectiveness of an EF Training Program for Pre-schoolers With a Severe CHD NCT06267430 | Erasmus Medical Center | N/A |
| Not Yet Recruiting | Comparative Effectiveness of Gadopiclenol for Evaluation of Adult Congenital Heart Anatomy and Hemodynamics NCT06406517 | University of California, San Diego | Phase 3 |
| Recruiting | iPSC Biobank of Biomarkers Diversity in Cardiovascular Disease NCT06371937 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | — |
| Completed | The Role of Thiamine After Transcatheter Closure in Children With Left-to-Right Shunt Congenital Heart Disease NCT06298344 | Universitas Sumatera Utara | EARLY_Phase 1 |
| Unknown | Cardiac Rehabilitation for Young People NCT05968521 | Greater Manchester Mental Health NHS Foundation Trust | N/A |
| Active Not Recruiting | A Comparison of Multidetector CT and TE in the Diagnosis of Congenital Cyanotic Heart Diseases NCT06749548 | Superior University | — |
| Recruiting | Online Support 4 CHD Kids & Caregivers NCT06075251 | The Hospital for Sick Children | N/A |
| Active Not Recruiting | Autus Valve Pivotal Study NCT05006404 | Autus Valve Technologies, Inc. | N/A |
| Recruiting | A Comprehensive Registry Study of the Whole Life Cycle of Patients With CHD NCT06611787 | Beijing Anzhen Hospital | — |
| Recruiting | Prognostic Model of Postnatal Circulation in Pulmonary Atresia-critical Stenosis With Intact Ventricular Septu NCT07095829 | Hospital Universitario 12 de Octubre | — |
| Recruiting | The Co-Op @ HeartWorks NCT06469918 | HeartWorks, Inc. | — |
| Terminated | Strong Hearts: A Remote, App-Enabled, Exercise Program for Patients With Congenital Heart Disease (Strong Hear NCT05853705 | Duke University | N/A |
| Recruiting | The Sequencing for Detection in Congenital Heart Disease (SD-CHD) Study NCT06244940 | Scripps Translational Science Institute | N/A |
| Unknown | Predictors of Aortic Root Dilatation in Tetralogy of Fallot Patients NCT06081855 | Assiut University | — |
| Unknown | Pulmonary Determinants of Cardiorespiratory Fitness in Fontan Patients NCT05684562 | Hacettepe University | — |
| Recruiting | Application of Ultrasound Technique in Locating the End of the Gastric Tube in Children Aged 0-6 Years NCT06650787 | Children's Hospital of Fudan University | N/A |
| Recruiting | Predictive Value of Neurovascular Coupling in Infants With COngenital Heart Disease NCT06190210 | Universitaire Ziekenhuizen KU Leuven | — |
| Completed | Influence of Positive-End-Expiratory-Pressure (PEEP) on Cardiac Output in Mechanically Ventilated Children NCT06270485 | Charite University, Berlin, Germany | N/A |
| Recruiting | Preeclampsia and Fetal Heart Malformations: Looking to Maternal Heart NCT07092644 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | N/A |
| Recruiting | A Study of Invasive Hemodynamic for MACHD Registry NCT05849025 | Mayo Clinic | — |
| Not Yet Recruiting | Repaired Tetralogy of Fallot: Risc Score From MRI & Clinical Data to Predict the Need for Change of Treatment NCT05916976 | University Medical Center Goettingen | N/A |
| Recruiting | A Parent-child Yoga Intervention for Reducing Attention Deficits in Children with Congenital Heart Disease: a NCT05997680 | Anne Gallagher | N/A |
| Recruiting | Effect of Local Warming for Arterial Catheterization in Pediatric Anesthesia NCT06041685 | Pusan National University Yangsan Hospital | N/A |
| Completed | Prevalence of Obesity Among Adult Patients With Congenital Heart Disease: a Population-based Study NCT06661434 | Rigshospitalet, Denmark | — |
| Unknown | Nutrition in Congenital Heart Disease NCT05891210 | Assiut University | — |
| Completed | FFP Usage in Pediatric CV Surgery NCT05819788 | University of Alberta | — |
| Completed | Dynamic Critical Congenital Heart Screening With Addition of Perfusion Measurements NCT05637814 | University of California, Davis | N/A |
| Withdrawn | Partial Heart Transplantation NCT06055556 | Duke University | N/A |
| Completed | HEARTPrep: A Virtually-delivered Psychosocial Intervention for Mothers Expecting a Baby With Congenital Heart NCT05129631 | Nemours Children's Clinic | N/A |
| Unknown | The Effect of 3D Heart Modelling on Family Quality of Life and Surgical Success NCT05852106 | Yeditepe University | N/A |
| Recruiting | OPTImal Treatment of Sinus VENOSUS Defect NCT05865119 | Centre Chirurgical Marie Lannelongue | N/A |
| Unknown | Microcirculation and Vascular Function After Fontan Surgery NCT05683067 | University of Leicester | — |
| Recruiting | Blood Conservation in Patients (3.5-12kg) Undergoing Congenital Cardiac Surgery NCT05881564 | Augusta University | N/A |
| Completed | Frailty and Non-Fragile Congenital Heart Disease NCT05824650 | Hacettepe University | — |
| Recruiting | Effects Branch PA Stenting d-TGA, ToF and TA NCT05809310 | UMC Utrecht | N/A |
| Withdrawn | Impedance During Cardiac Catheterization to Build a Non-Invasive Cardiac Output Algorithm NCT06171698 | Johns Hopkins University | N/A |
| Unknown | ABL90 FP MC Neonatal Arterial, Venous, Capillary Blood NCT06078943 | Radiometer Medical ApS | N/A |
| Completed | Assessing and Promoting Resilience in Patients With Adult Congenital Heart Disease NCT04738474 | University of Washington | N/A |
| Completed | Exercise Training in Children With Corrective Cardiac Surgeries NCT05763238 | Riphah International University | N/A |
| Completed | Theophylline Effects in the Fontan Circulation NCT05717049 | Oslo University Hospital | Phase 2 |
| Unknown | " Evaluation of Safety and Efficacy of Empagliflozin and Sacubitril/Valsartan for CHF With Reduced Ejection Fr NCT05580510 | Instituto Nacional de Cardiologia Ignacio Chavez | Phase 2 / Phase 3 |
| Recruiting | Autologous Induced Pluripotent Stem Cells of Cardiac Lineage for Congenital Heart Disease NCT05647213 | HeartWorks, Inc. | Phase 1 |
| Recruiting | Adult Congenital Heart Disease International EValuation of the Effectiveness of SGLT2i Registry NCT06932081 | Leiden University Medical Center | — |
| Unknown | Investigation of Adults With Congenital Heart Disease in the Scope of the ICF NCT05774158 | Hacettepe University | — |
| Recruiting | Creative Music Therapy in Newborns With Congenital Heart Disease NCT05702203 | University Children's Hospital, Zurich | N/A |
| Recruiting | HIIT in Youth With Congenital Heart Disease (MedBIKE) NCT04575883 | University of Alberta | N/A |
| Recruiting | Cardiac Resynchronization Therapy in Adult Congenital Heart Disease With Systemic Right Ventricle: RIGHT-CRT NCT05524324 | Assistance Publique - Hôpitaux de Paris | N/A |
| Enrolling By Invitation | EXCOR Active Driving System for the EXCOR Pediatric VAD IDE Study NCT05610787 | Berlin Heart, Inc | N/A |
| Completed | Evaluation of VITLS Compared to Traditional Inpatient Monitoring in Cardiac Shunt-Dependent Children NCT05526768 | Baylor College of Medicine | N/A |
| Unknown | Optical Coherence Tomography Angiography (OCTA) in Children's Cardiac Surgery NCT05568849 | Great Ormond Street Hospital for Children NHS Foundation Trust | N/A |
| Completed | Lymphatic Function in Patients With Fontan Circulation: Effect of Physical Training NCT05934578 | University of Sao Paulo | N/A |
| Recruiting | Video Laryngoscopy Versus Direct Laryngoscopy for Nasotracheal Intubation NCT05902013 | Medical University of Vienna | N/A |
| Completed | Influence of Preop Fibrinogen on Blood in Pediatric Cardiac Surgery NCT05525195 | Brugmann University Hospital | — |
| Unknown | Comparison Between Multislice CT and Echocardiography in Diagnosis of Pediatric Congenital Heart Disease NCT05546008 | Assiut University | — |
| Recruiting | Development of CIRC Technologies NCT05654272 | The Cleveland Clinic | — |
| Recruiting | Fontan Associated Liver Disease and the Evaluation of Biomarkers for Disease Severity Assessment NCT05213598 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | — |
| Recruiting | Resuscitation Registry in CHD NCT05373498 | Leipzig Heart Science gGmbH | — |
| Completed | Effect of Muscle Strengthening Training in Adults with Fontan Circulation NCT05454254 | Umeå University | N/A |
| Completed | Efficacy of a Web-Based Emotion Regulation Intervention for Patients With Congenital Heart Disease NCT05862909 | Heidelberg University | N/A |
| Recruiting | Evaluation of the Correlation Between Vein Size Inferior Cava and Right Atrial Pressure in Pediatric Age and C NCT06776133 | IRCCS Azienda Ospedaliero-Universitaria di Bologna | — |
| Completed | Ultrasound-Guided Serratus Anterior Plane Block Versus Erector Spinae Plane Block in Pediatric Cardiac Surgery NCT05526469 | Ain Shams University | N/A |
| Unknown | Perioperative Transfusion Strategies in Adult Congenital Heart Disease Patients Undergoing Cardiac Surgery NCT04973514 | Brugmann University Hospital | — |
| Unknown | Muscle Catabolism and Outcomes in Children Following Cardiac Surgery NCT04998643 | Boston Children's Hospital | — |
| Recruiting | Ventripoint Single Ventricle Study NCT05262907 | Duke University | N/A |
| Unknown | Protocol to Support Breastfeeding for Postpartum Women and Mothers of Babies With Congenital Heart Disease NCT06025864 | Instituto de Cardiologia do Rio Grande do Sul | N/A |
| Recruiting | The Relationship Between Brain MRI Phenotypes, Genes and Cognitive Outcome in CHD Adults NCT05258981 | Boston Children's Hospital | N/A |
| Completed | Limbs Range of Motion Exercises Along With Chest Physical Therapy After Correction of Congenital Heart Disease NCT05425173 | Riphah International University | N/A |
| Active Not Recruiting | Efficacy of Triple-Combination Therapy in Severe PAH-CHD NCT06196801 | Guangdong Provincial People's Hospital | — |
| Recruiting | Evaluation of Pro-Inflammatory Leukocyte Activity in Patients Undergoing Cardiac Surgery NCT04299828 | Boston Children's Hospital | — |
| Completed | The Effects of Telerehabilitation and Exercise Training in Pediatric Arrhythmia Patients With Pacemakers NCT05454501 | Hacettepe University | N/A |
| Unknown | Analysis of Risk Factors and Prognosis of Pediatric Patients After Operations for Congenital Heart Disease NCT06031831 | National Taiwan University Hospital | — |
| Completed | Congenital Heart Disease: Impact on Learning and Development in Down Syndrome (CHILD-DS) NCT05312177 | Carelon Research | — |
| Enrolling By Invitation | Nitric Oxide Effect on Brain and Kidney in Pediatric Patients Undergoing Cardiopulmonary Bypass NCT05101746 | Vanderbilt University Medical Center | Phase 2 / Phase 3 |
| Completed | ATC Vs PSV for Ventilatory Weaning of Pediatrics Postcardiac Surgery NCT05344872 | University of Alexandria | N/A |
| Unknown | A Predictive Score System for AKI Following Pediatric Cardiac Surgery NCT05489263 | China National Center for Cardiovascular Diseases | — |
| Unknown | Congenital Heart Initiative-Redefining Outcomes and Navigation to Adult Centered Care NCT05185232 | Children's National Research Institute | — |
| Completed | Enhanced External Counterpulsation in Patients With Fontan Circulation NCT04956952 | Boston Children's Hospital | N/A |
| Terminated | Retrospective Evaluation of Photo-oxidized Decellularized Bovine Pericardium in Cardiac Repair or Reconstructi NCT05314868 | Artivion Inc. | — |
| Recruiting | Atrial Late Gadolinium Enhancement in Patients with Repaired Congenital Heart Disease NCT05241418 | Boston Children's Hospital | — |
| Completed | Speech Therapy Online Approach for Children With Congenital Heart Desease in Pre and Post Surgical Period NCT07481565 | Instituto de Cardiologia do Rio Grande do Sul | N/A |
| Completed | Acute Normovolemic Hemodilution in Complex Cardiac Surgery NCT05049590 | University of California, Los Angeles | Phase 3 |
| Unknown | Gender Difference in NET Activation in Patients With Congenital Heart Disease and Heart Failure NCT05263843 | Assistance Publique - Hôpitaux de Paris | — |
| Completed | Virtual Remote Physiological Monitoring Program of Children With Heart Disease NCT05034354 | University of Alberta | N/A |
| Unknown | Cardiac Rehabilitation in Congenital Heart Disease: Effects on Brain and Cognitive Functions NCT05195788 | Montreal Heart Institute | N/A |
| Unknown | Patterns of Congenital Heart Diseases at Sohag University Hospital NCT05196438 | Sohag University | — |
| Completed | The Impact of an Innovative eHealth Transition Intervention on Self-Management Skills Among Young Adults With NCT04463446 | University of Alberta | N/A |
| Unknown | Contribution of Multimodal Imaging in Early Coarctation NCT05203874 | University Hospital, Montpellier | — |
| Recruiting | An Integrated Prenatal and Postnatal Treatment Model for the Treatment of Newborns With Critical Congenital He NCT06768008 | Beijing Anzhen Hospital | — |
| Completed | Infective Endocarditis in Percutaneous Pulmonary Revalvulation: Comparison Between Melody and Sapien Valves NCT06186258 | Centre Chirurgical Marie Lannelongue | — |
| Unknown | The Application of a Wireless Sensor Technology for Vital Statistics in CHILDREN AND ADULTS NCT01845506 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | N/A |
| Recruiting | Pathophysiologic Mechanism for Arrhythmias and Impaired Aerobic Capacity in Tetralogy of Fallot and Other Cong NCT05122962 | Mayo Clinic | — |
| Active Not Recruiting | Harmony TPV Post-Approval Study NCT05077774 | Medtronic Cardiovascular | N/A |
| Unknown | Red Flags for Cardiac Examination for Early Detection of Congenital Heart Disease NCT04801251 | Assiut University | N/A |
| Completed | Preoperative Educational Videos on Maternal Stress Whose Children Received Congenital Heart Disease Surgery: D NCT06107491 | Chung Shan Medical University | N/A |
| Withdrawn | Nitric Oxide During CPB to Reduce AKI in Neonates NCT03946462 | Fabio Savorgnan | Phase 1 |
| Completed | High-exchange ULTrafiltration to Enhance Recovery After Pediatric Cardiac Surgery NCT04920643 | IWK Health Centre | N/A |
| Completed | Paediatric Brain Injury Following Cardiac Interventions NCT04992793 | University of Leicester | — |
| Unknown | Transcatheter Pulmonary Valve Implantation With SAPIEN 3 Valve NCT05264181 | Centre Chirurgical Marie Lannelongue | — |
| Completed | The Level of sST2 in Pediatric Heart Failure NCT06347510 | Eskisehir Osmangazi University | — |
| Completed | Central Venous to Arterial CO2 Difference and Low Cardiac Output Syndrome Related Outcomes in Children After C NCT06292910 | Prince of Songkla University | — |
| Completed | Evaluation of the Prevalence and Clinical Manifestation of SARS-CoV-2 Infection in a Population of Adult and P NCT06784687 | IRCCS Azienda Ospedaliero-Universitaria di Bologna | — |
| Recruiting | IPSC Repository of Pediatric Cardiovascular Disease NCT05550324 | Mingtao Zhao | — |
| Unknown | Use of a Predictive Analytics Algorithm to Optimize Weaning of Inotropes Following Pediatric Cardiac Surgery NCT04600700 | Boston Children's Hospital | — |
| Completed | Correlation Between 3D Echocardiography and Cardiopulmonary Exercise Testing in Patients With Single Ventricle NCT05118152 | University Hospital, Montpellier | — |
| Completed | Effect of Probiotics on Patients With Congenital Heart Disease Following Cardiopulmonary Bypass NCT06295575 | Nanjing Children's Hospital | N/A |
| Completed | Digital Health Nudging in Adolescents With Congenital Heart Disease NCT04933786 | Deutsches Herzzentrum Muenchen | N/A |
| Unknown | Fetal Cardiac Magnetic Resonance in Detection of CHD NCT05066399 | University Hospital, Bonn | — |
| Terminated | Specialized Pacing for Patients With Congenital Heart Disease NCT03361189 | University of California, Los Angeles | Phase 2 / Phase 3 |
| Unknown | Psychological Functioning of Children and Adolescents With CHD andTheir Parents, An Intervention Based Study NCT05109806 | Government College University Faisalabad | N/A |
| Unknown | Transition Care Model for Adolescents With Congenital Heart Disease NCT05713591 | IRCCS Policlinico S. Donato | N/A |
| Completed | 2D-speckle Tracking in Pediatric Renal Chronic Disease NCT04897672 | University Hospital, Montpellier | — |
| Unknown | Mobile Electrocardiogram Monitoring for Detecting Arrhythmias in Children NCT05140343 | Centro Medico Teknon | N/A |
| Completed | Effect of Feeding With Nutrient Dense Formula in Malnourished Infants and Children With Congenital Heart Defec NCT04795076 | Shahid Beheshti University | N/A |
| Completed | Quality of Life and Neurodevelopment Assessment of Children With Congenital Heart Disease Aged 2 to 4 Years NCT04812210 | University Hospital, Montpellier | — |
| Recruiting | Stress Echo 2030: the Novel ABCDE-(FGLPR) Protocol to Define the Future of Imaging NCT05081115 | Fatebenefratelli Hospital | — |
| Terminated | Predicting Arrhythmogenic Risk in Congenital Heart Patients: the PRECISION Study NCT04768634 | Boston Children's Hospital | N/A |
| Completed | Pharmacokinetics of Acetaminophen in Pediatric Patients With Congenital Heart Disease NCT04278625 | Peter Winch | — |
| Unknown | NeuroCardio Baby Research Outpatient Clinic: Study on the Neurodevelopment of Infants With Congenital Heart Di NCT05907109 | Instituto de Cardiologia do Rio Grande do Sul | N/A |
| Completed | Fontan Physiology Ventilation Strategy NCT04672538 | University of Pittsburgh | N/A |
| Unknown | Cardiopulmonary Effect of Mechanical Ventilation in Children With Right Ventricular Hypertrophy NCT04825054 | Limin Zhu | N/A |
| Active Not Recruiting | Training in Exercise Activities and Motion for Growth (TEAM 4 Growth) RCT NCT04702373 | Carelon Research | Phase 3 |
| Completed | Congenital Heart Anomaly Risk in Maternal Enteroviral Infection and Diabetes NCT04769167 | Washington University School of Medicine | N/A |
| Completed | Microvascular Dysfunction in Adults With Congenital Heart Disease and the Effect of Exercise Training NCT06715137 | University Hospital, Antwerp | N/A |
| Completed | Subcostal Transverse Abdominis Plane Block for Epigastric Cardiac Pacemaker Operation NCT04570878 | Seoul National University Hospital | N/A |
| Unknown | Outcome of Balloon Pulmonary Valvuloplasty in Patients With Congenital Pulmonary Stenosis in Terms of Reverse NCT05828524 | Assiut University | — |
| Unknown | Protecting Brains and Saving Futures - the PBSF Protocol NCT03786497 | Protecting Brains Saving Futures | — |
| Unknown | Additive Anti-inflammatory Action for Critically Ill Patients With Cardiovascular Surgery (Xuebijing) IV NCT04993794 | Nanjing Medical University | N/A |
| Recruiting | Effect of Fetal Aortic Valvuloplasty on Outcomes NCT05386173 | Queen Silvia Children's Hospital, Gothenburg, Sweden | — |
| Completed | "Critical State" Early Warning Score After CHD Surgery and Rapid Response Team NCT06578312 | Chinese Academy of Medical Sciences, Fuwai Hospital | — |
| Unknown | Interpretation of Fetal Echocardiography by Artificial Intelligence NCT05090306 | University of Medicine and Pharmacy Craiova | — |
| Completed | Dopamine Versus Norepinephrine Under General Anesthesia NCT04536194 | Children's Hospital of Fudan University | Phase 3 |
| Active Not Recruiting | Peer Coaching Intervention in Young Adults With Congenital Heart Disease NCT04271358 | Duke University | N/A |
| Active Not Recruiting | Improving Patient and Family Health Using Family-Centered Outcomes and Shared Decision-Making NCT04437069 | University of Utah | N/A |
| Recruiting | The PAtients pResenTing With COngenital HeaRt DIseAse Register (ARTORIA-R) NCT04848844 | Universitätsklinikum Hamburg-Eppendorf | — |
| Unknown | Dexmedetomidine Neuroprotection in Pediatric Cardiac Surgery NCT04484922 | Seoul National University Hospital | N/A |
| Completed | Ultrafiltration in Pediatric Cardiac Surgery: An Observational Cohort Study NCT05154864 | IWK Health Centre | — |
| Completed | Cardiac Acute Transitioning Care to Home (CATCH) App Data Repository NCT04498728 | Children's Mercy Hospital Kansas City | — |
| Unknown | Percutaneous Edge To Edge Repair for the Treatment of Severe Tricuspid Valve Regurgitation in High-surgical Ri NCT05052177 | University of Bordeaux | — |
| Unknown | Pulmonary Capillary Recruitment in Fontan Patients NCT04292483 | Jewish General Hospital | — |
| Unknown | Better Mechanistic Understanding of and Risk Stratification for Ventricular Tachyarrhythmias Through ECGI NCT04548804 | Maastricht University Medical Center | N/A |
| Unknown | Procedural Outcomes of Percutaneous PDA Closure: Comparative Study Between Different Devices. NCT04303793 | Assiut University | N/A |
| Completed | Extubation Times in Postoperative Congenital Cardiovascular Surgeries NCT05332860 | Bursa Yuksek Ihtisas Training and Research Hospital | — |
| Unknown | New Designed ePTFE Valved Conduits for Surgical Reconstruction of Right-ventricular Outflow Tract NCT04152967 | Children's Hospital of Fudan University | N/A |
| Unknown | The Effect of Fluids Flushed in Pediatric Cardiac Catheterization Procedures on Lung Ultrasound Score NCT04311918 | Cairo University | — |
| Completed | Impact of Covid-19 in Congenital Heart Disease NCT04336384 | University Hospital, Montpellier | — |
| Completed | Evolution of Cardiopulmonary Fitness in Children With Congenital Heart Disease NCT04815577 | University Hospital, Montpellier | — |
| Completed | Home Based Program Physical Training in Congenital Heart Disease NCT06519084 | University of Sao Paulo General Hospital | N/A |
| Unknown | Clinical Audit On Management Of Congenital Heart Disease In ACUH NCT03850223 | Assiut University | — |
| Terminated | ZEPLAST- PED: ZEro_PLASma Trial in Small Infants Undergoing Cardiac Surgery NCT04434001 | IRCCS Policlinico S. Donato | Phase 2 |
| Terminated | Cold Heart Study: A Randomized Pilot Trial of Surfactant Therapy NCT04181255 | University of Michigan | Phase 1 |
| Completed | Redesigning the Care Journey of Patients With Single-ventricle Congenital Heart Disease NCT04613934 | University of Texas at Austin | — |
| Completed | SNOO Smart Sleeper for Infants With CHD NCT04534335 | Children's Mercy Hospital Kansas City | — |
| Completed | Epidemiology of Congenital Heart Disease in France NCT04740177 | University Hospital, Montpellier | — |
| Completed | The Relationship Between Having a Positive Mindset and Exercise Capacity in Patients With Congenital Heart Dis NCT03912025 | Boston Children's Hospital | — |
| Recruiting | Implementing Models for Mechanical Circulatory Support Presurgical Assessment in Congenital Heart Disease Trea NCT03891160 | Columbia University | N/A |
| Completed | Point of Care Ultrasound Measurements of Perioperative Edema in Infants With Congenital Heart Disease NCT04151160 | University of Colorado, Denver | — |
| Unknown | Prospective Evaluation of Programmed Ventricular Stimulation Before Pulmonary Valve Replacement in Patients Wi NCT04205461 | Paris Cardiovascular Research Center (Inserm U970) | — |
| Completed | Prognostic Value of NLR, TLR, and ALC in Predicting ToF Primary Repair Outcome NCT05976204 | National Cardiovascular Center Harapan Kita Hospital Indonesia | — |
| Unknown | Catheter Ablation in Congenital Heart Disease: French National Prospective Registry NCT04202796 | Paris Cardiovascular Research Center (Inserm U970) | — |
| Unknown | Altered Cerebral Growth and Development in Infants With Congenital Heart Disease NCT04233775 | University Children's Hospital, Zurich | — |
| Terminated | Use of Oxandrolone to Promote Growth in Infants With HLHS NCT04090697 | Carelon Research | Phase 1 / Phase 2 |
| Recruiting | A 10-Minute Cardiovascular Magnetic Resonance Protocol for Cardiac Disease NCT04464655 | McGill University Health Centre/Research Institute of the McGill University Health Centre | — |
| Completed | Proposal for Parental Guidance and Early Stimulation in Children With Congenital Heart Disease: Randomized Tri NCT04152330 | Instituto de Cardiologia do Rio Grande do Sul | N/A |
| Completed | NT-proBNP Levels in the Prediction of Intrapartum and Postpartum Events in Adult Congenital Heart Disease Pati NCT04231591 | Mayo Clinic | — |
| Completed | 3D Cine Cardiovascular Magnetic Resonance NCT03583775 | Boston Children's Hospital | — |
| Completed | Pediatric Enhanced Recovery After Cardiac Surgery NCT05665712 | University of Alberta | — |
| Completed | Improving Critical Congenital Heart Disease Screening With Addition of Perfusion Measurements NCT04056104 | University of California, Davis | N/A |
| Withdrawn | Nitric Oxide During Cardiopulmonary Bypass in Neonates to Reduce Risk of Acute Kidney Injury NCT04259684 | Children's Hospital Medical Center, Cincinnati | Phase 2 / Phase 3 |
| Completed | eHealth as an Aid for Facilitating and Supporting Self-management in Families With Long-term Childhood Illness NCT04150120 | Lund University | N/A |
| Terminated | Pre Bypass Ultrafiltration (PBUF) in Children Requiring Cardiopulmonary Bypass NCT03576534 | Boston Children's Hospital | N/A |
| Completed | Comparison of Home and Standard Clinic Monitoring of INR in Patients With CHD NCT04136379 | University of Ulster | — |
| Completed | 3D Airway Model for Pediatric Patients NCT04814888 | Pusan National University Yangsan Hospital | — |
| Unknown | INSPIRIS RESILIA Valve in Pulmonary Position NCT05583656 | Medical University of Vienna | — |
| Completed | Utility of Lung Ultrasound in the Estimation of Extravascular Lung Water in Pediatric Population NCT04417790 | Post Graduate Institute of Medical Education and Research, Chandigarh | — |
| Completed | Pharmacokinetics and Safety Profile of Digoxin in Infants With Single Ventricle Congenital Heart Disease NCT03877965 | Christoph P Hornik, MD MPH | — |
| Terminated | Evaluating Right Ventricular (RV) Size and Function Using the Upper Valley RV Algorithm and Novel Imaging Moda NCT03935178 | Dartmouth-Hitchcock Medical Center | — |
| Unknown | A Comparative Study of Three Modes of Ventilation During CPB in Pediatrics With Pulmonary Hypertension Undergo NCT04262037 | Cairo University | N/A |
| Completed | Assessment of Patterns of Patient Reported Outcomes in Adults With Congenital Heart Disease - International St NCT04902768 | KU Leuven | — |
| Terminated | Acute Effects of the Prostaglandin (Alprostadil) on Cerebral and Pulmonary Flow NCT04054115 | The Hospital for Sick Children | Phase 1 |
| Completed | Sophrology and Congenital Heart Disease NCT03999320 | University Hospital, Montpellier | N/A |
| Completed | Apixaban in Adults With Congenital Heart Disease and Atrial Arrhythmias: the PROTECT-AR Study NCT03854149 | AHEPA University Hospital | — |
| Completed | Regional Anesthesia for Cardiothoracic Enhanced Recovery (RACER) Study NCT03611374 | Stanford University | N/A |
| Unknown | Effects of Prostaglandin E1 Treatment on Pyloric Wall in Newborns NCT04496050 | Hacettepe University | — |
| Completed | Outcome of Patients With Congenital Heart Disease NCT03913520 | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | N/A |
| Unknown | Acute Maternal Hyperoxygenation in CHD NCT03944837 | The Hospital for Sick Children | N/A |
| Completed | A Pilot Study of Optic Nerve Ultrasound Following Cardiopulmonary Bypass NCT03757312 | Marco Corridore | N/A |
| Completed | GoalKeeper: Intelligent Information Sharing for Children With Medical Complexity NCT03620071 | Stanford University | N/A |
| Enrolling By Invitation | Characterizing the Effect of Dopamine on Markers of Lymph Re-circulation in Fontan-associated Protein-losing E NCT03322345 | University of Michigan | — |
| Completed | BabySparks Developmental Application Pilot Study NCT03867903 | Children's Mercy Hospital Kansas City | — |
| Completed | Stress Ulcer Prophylaxis Versus Placebo in Critically Ill Infants With Congenital Heart Disease NCT03667703 | Boston Children's Hospital | Phase 4 |
| Completed | Comparison of PRISM III, PIM2 and PELOD Scoring Systems NCT04848168 | Antalya Training and Research Hospital | — |
| Unknown | Autologous Umbilical Cord Blood Treatment of Neonate With CHD NCT03558269 | Sheba Medical Center | Phase 1 / Phase 2 |
| Completed | Quality of Life Assessment of Children With Congenital Heart Disease Aged 5 to 7 Years NCT03931096 | University Hospital, Montpellier | — |
| Completed | Impact of a Cardiac and Mental Health Rehab Program on Well-Being and Fitness in Young Adults With Fontan Circ NCT06844149 | Samsung Medical Center | N/A |
| Recruiting | European Prospective Registry on Anomalous Aortic Origin of the Coronary Arteries NCT06089902 | University of Padova | — |
| Completed | Effects of Anesthetic Techniques on Renal Function NCT04030481 | Huiying Shao | — |
| Recruiting | The Swiss Neurodevelopmental Outcome Registry for Children With CHD NCT05996211 | University Children's Hospital, Zurich | — |
| Completed | Accuracy of Risk Prediction Scores in Pregnant Women NCT04221048 | University Hospital, Montpellier | — |
| Unknown | Improvement on Diagnosis of Fetal Congenital Heart Disease Based on Multi-center Collaboration in China NCT03119155 | Beijing Anzhen Hospital | — |
| Recruiting | Copenhagen Baby Heart Study - Impact NCT05838079 | Henning Bundgaard | — |
| Completed | Sudden Cardiac Death in Systemic Right Ventricle NCT03833843 | European Georges Pompidou Hospital | — |
| Recruiting | ATrial Tachycardia PAcing Therapy in Congenital Heart NCT03209583 | Ian Law | — |
| Completed | Ventricular and Pulmonary Vascular Reserve After the Fontan Operation NCT03853837 | Mayo Clinic | — |
| Completed | Evaluation of Web-based Transition Education to Enhance Transition Readiness NCT03303248 | University of Michigan | N/A |
| Unknown | Mechanical Ventilation During Cardiopulmonary Bypass NCT03629574 | Azienda Ospedaliera di Padova | N/A |
| Completed | Determining the Effect of Two Different Methods in Children to Maintain Drain Patency After Cardiac Surgery NCT04454294 | Acibadem University | N/A |
| Terminated | Paravertebral Nerve Blocks in Neonates NCT03408340 | Emory University | Phase 4 |
| Unknown | Myocardial FIbrosis in Repaired Tetralogy of FAllot- FIFA Study) NCT04737135 | Hospital Universitari Vall d'Hebron Research Institute | — |
| Recruiting | Peri-operative Nutrition in Infants With Congenital Heart Disease NCT03626480 | Guangzhou Medical University | — |
| Unknown | Nasal vs. Oral Intubation for Neonates Requiring Cardiac Surgery NCT05378685 | University of Virginia | N/A |
| Recruiting | Fetal Electrophysiologic Abnormalities in High-Risk Pregnancies Associated With Fetal Demise NCT03775954 | Medical College of Wisconsin | — |
| Unknown | Thiamine Influenced on Substrate Energy Effectiveness in Indonesian Children Undergoing Cardiopulmonary Bypass NCT04453761 | National Cardiovascular Center Harapan Kita Hospital Indonesia | Phase 4 |
| Terminated | Pharmacokinetic Study of Intranasal Dexmedetomidine in Pediatric Patients With Congenital Heart Disease NCT03417999 | Children's Hospital of Philadelphia | Phase 1 |
| Active Not Recruiting | French Observatory of Congenital Ventricular Septal Defect With Pulmonary Overload NCT03363932 | French Cardiology Society | — |
| Completed | Web-based Motor Intervention to Increase Health Related Physical Fitness in Children With Congenital Heart Dis NCT03488797 | Deutsches Herzzentrum Muenchen | N/A |
| Completed | Utility of MRI With Doppler Ultrasound Gating for Advanced Fetal Monitoring NCT03541291 | The Hospital for Sick Children | N/A |
| Completed | 4DFlow Magnetic Resonance Imaging in Patients With Pulmonary Hypertension Associated With Congenital Heart Dis NCT03928002 | Centre Chirurgical Marie Lannelongue | N/A |
| Unknown | Fetal Growth and Pregnancy Complications Among Women With Heart Disease NCT03657823 | Oslo University Hospital | — |
| Completed | Characterization of the Cardiac Reinnervation of Patients With Transposition of the Great Arteries Long After NCT03469843 | Hospital Universitari Vall d'Hebron Research Institute | — |
| Completed | Just TRAC It! Transitioning Responsibly to Adult Care Using Smart Phone Technology NCT03429335 | University of Alberta | N/A |
| Completed | Development of a Quality of Life Assessment Tool for Adult Patients With a Congenital Heart Disease, Having Ha NCT03917706 | Pierre Wauthy | — |
| Unknown | Platelets or Fibrinogen as First-line Treatment for Bleeding During Pedatric Heart Surgery NCT04807621 | Sahlgrenska University Hospital | Phase 2 |
| Completed | Enhanced Physical Activity Support in Congenital Heart Disease Clinical Care NCT03435354 | Children's Hospital of Eastern Ontario | N/A |
| Completed | Clinical Characteristics and Associations of the "Good Fontan" Patient NCT03470428 | Boston Children's Hospital | — |
| Completed | Cardiac Biomarkers in Patients With Single Ventricle Physiology NCT03678909 | Baylor College of Medicine | — |
| Completed | Evaluation of the Microcirculation During the Corrective Surgery of Congenital Heart Defects in Children NCT03144258 | National Institute of Cardiology, Laranjeiras, Brazil | — |
| Completed | Non-invasive Hemoglobin Monitoring in Congenital Heart Diseased Children NCT03248830 | Cairo University | — |
| Completed | Impact of a Structural Phonation Training on Respiratory Muscle Function in Patients With Structural Heart Dis NCT03297918 | University Hospital, Basel, Switzerland | N/A |
| Completed | A Study to Evaluate the Effects of a New Formula on the Growth, Safety and Tolerance of Infants With Growth Fa NCT03563391 | Nutricia North America | N/A |
| Unknown | The Research of the Effect of Sevoflurane on Brain-protection of Cardiac Surgery in Infants. NCT03366597 | Jun Ma | N/A |
| Completed | Correlation Between Quality of Life and Aerobic Physical Fitness of Patients With a Systemic Right Ventricle NCT03379831 | University Hospital, Montpellier | — |
| Completed | Does Modified Ultrafiltration Affect Thromboelastography Results? NCT03214120 | Wake Forest University Health Sciences | — |
| Completed | Lymphatic Morphology of Fontan Patients NCT04163653 | University of Aarhus | — |
| Completed | Auscultation and Pulse Oximetry Combined Screening of Neonatal Congenital Heart Disease NCT05105880 | Women and Children's Hospital of Linyi City | — |
| Completed | Transverse Thoracic Plane Block in the Pediatric Cardiac Patient NCT04138745 | Ochsner Health System | — |
| Completed | Neurodevelopmental Disorders in Children With Congenital Heart Disease NCT03360370 | University Hospital, Lille | — |
| Unknown | Biomarkers in Pediatric Congenital Heart Disease and PAH NCT04130243 | University Medical Center Groningen | — |
| Completed | Nutritional Prehabilitation Program and Cardiac Surgery Outcome in Pediatrics NCT02475759 | Ain Shams University | N/A |
| Completed | dbGaP Protocol: The Pediatric Cardiac Genetics Consortium (PCGC) NCT03347214 | National Heart, Lung, and Blood Institute (NHLBI) | — |