Clinical Trials Directory

Trials / Sponsors / Children's National Research Institute

Children's National Research Institute

Academic / Other · 119 registered clinical trials39 currently recruiting.

StatusTrialPhaseStarted
RecruitingSelective Antigen Specific T Cells and CAR T Cells in Subjects With Relapsed/Refractory Embryonal Tumors (SABR
Rhabdomyosarcoma, Ewing Sarcoma, Neuroblastoma
Phase 12026-01-27
Enrolling By InvitationCreating a Flexible Curriculum Tool for Pediatric Palliative Care Rotating Learners
Palliative Care Education
N/A2026-01-01
RecruitingCharacterization of Acute Pain
Acute Pain, Postoperative, Postoperative Pain, Acute Pain
2025-12-02
Enrolling By InvitationPalliative Care Needs of Children With Rare Diseases and Their Families
Trisomy 13 Syndrome, Arthrogryposis Congenita Multiplex With Intestinal Atresia, Asparagine Synthetase Deficiency
N/A2025-10-02
Not Yet RecruitingA Phase 0/1 Study of cDNA for TP53, Checkpoint Inhibition and Radiation in Children With Recurrent, Progressiv
CNS Malignancies, Medulloblastoma Recurrent, ATRT Recurrent
EARLY_Phase 12025-07-01
RecruitingPragmatic Clinic-Based Trial of a Mindfulness Based Intervention for Mood Concerns in Youth With Type 1 Diabet
Type 1 Diabetes (T1D)
N/A2025-05-15
RecruitingAdvancing Feasibility and Acceptability of Digital Cognitive Rehabilitation in Sickle Cell Disease
Sickle Cell Disease
N/A2025-03-05
Not Yet RecruitingUse of Equity Report Cards to Mitigate Disparities in Emergency Medical Services (EMS) Care for Injured Childr
Pain, Acute
N/A2025-01-01
RecruitingThe Exhale Study: Treating Maternal Depression in an Urban Pediatric Asthma Clinic
Asthma in Children, Depression
N/A2024-10-15
RecruitingDexamethasone Use in Pediatric Rhabdomyolysis Patients in Addition to Standard Protocols
Rhabdomyolysis
Phase 12024-10-01
RecruitingEfficacy of a Novel Prototype Gastrostomy Tube Anchor Dressing
Gastroenterology Surgery, Tube Feeding
N/A2024-09-24
RecruitingImmunotherapy for Malignant Pediatric Brain Tumors Employing Adoptive Cellular Therapy (IMPACT)
Medulloblastoma, Childhood, Atypical Teratoid/Rhabdoid Tumor of CNS, Embryonal Tumor With Multilayered Rosettes
Phase 12024-09-20
RecruitingVirtual Reality During Lumbar Punctures in Acute Lymphoblastic Leukemia
Acute Lymphoblastic Leukemia, Pediatric
N/A2024-08-30
RecruitingUsing Mobile Health (mHealth) to Improve STI Treatment Adherence Among Adolescents
Sexually Transmitted Diseases
N/A2024-06-03
RecruitingSickle Cell Disease Transplant Using a Nonmyeloablative Approach for Patients With Anti-donor Red Cell Antibod
Sickle Cell Disease
Phase 22024-04-03
RecruitingNavigating Pregnancy and Parenthood With Lyme Disease
Lyme Disease, Post Treatment Lyme Disease, Chronic Lyme Disease
2024-03-20
RecruitingIndividualized Nutrition to Optimize Preterm Infant Growth and Neurodevelopment
Very Preterm Maturity of Infant, Very Low Birth Weight Infant
N/A2024-02-08
RecruitingAugmented Reality For MRI-Guided Interventions
Infections, Pain, Diagnosis
N/A2024-02-06
CompletedRare Group Problem Management Plus
Anxiety, Depressive Symptoms, Post-traumatic Stress Disorder
N/A2024-02-05
RecruitingFocused Ultrasound Pallidotomy for Dyskinetic Cerebral Palsy in Pediatric and Young Adult Subjects
Cerebral Palsy, Dyskinetic, Secondary Dystonia
N/A2024-01-26
RecruitingTherapeutic Endpoint in Pediatric IBD Conditions
Inflammatory Bowel Diseases, Colitis, Ulcerative, Crohn Disease
2023-11-27
RecruitingPregnancy and Early Neurodevelopmental Outcomes Following In Utero Lyme Disease Exposure
Lyme Disease, Post-Treatment Lyme Disease, Chronic Lyme Disease
2023-07-01
RecruitingEvaluation of The Food Allergy Mastery Program
Food Allergy in Children
N/A2023-06-26
RecruitingFeasibility/Acceptability of Attentional-Control Training in Survivors
Pediatric Cancer, Pediatric ALL, Pediatric Brain Tumor
N/A2023-06-14
RecruitingHealth Information Technology to Reduce Disparities in Adolescent Health Outcomes: A Pragmatic Trial
Sexually Transmitted Diseases
N/A2023-03-08
UnknownAcute Concussion and Melatonin
Concussion, Mild, Concussion, Brain, Pediatric ALL
Phase 22023-03-01
RecruitingPAINED: Project Addressing INequities in the Emergency Department
Pain, Appendicitis, Bias, Racial
N/A2023-02-27
RecruitingInternational Rare Brain Tumor Registry
Astroblastoma, BCOR ITD Sarcoma, CNS Sarcoma
2023-01-01
RecruitingFeasibility and Efficacy of Attentional-Control Training in Sickle Cell Disease
Sickle Cell Disease, Attention Deficit, Cognitive Deficit in Attention
N/A2022-12-20
CompletedInterventions to Promote Well-being of Nightshift Nursing Team Members
Professional Quality of Life
N/A2022-12-07
WithdrawnA Pilot Study of Thermodox and MR-HIFU for Treatment of Relapsed Solid Tumors
Solid Tumors, Soft Tissue Sarcoma, Ewing Sarcoma
Phase 22022-11-10
Active Not RecruitingGrowth Hormone in a Patient With a Dominant-Negative GHR Mutation
Growth Disorders
Phase 22022-08-26
Active Not RecruitingThe DC Mother-Infant Behavioral Wellness Program
Perinatal Depression, Perinatal Anxiety, Prenatal Stress
N/A2022-08-22
Active Not RecruitingPedBot Ankle Rehablitation
Cerebral Palsy
2022-07-28
Enrolling By InvitationBehavioral Intervention for Celiac Disease
Celiac Disease
N/A2022-06-07
RecruitingOmalizumab Before Onset of Exacerbations
Asthma in Children, Atopy, Viral Upper Respiratory Infection
Phase 22022-05-01
UnknownCongenital Heart Initiative-Redefining Outcomes and Navigation to Adult Centered Care
Congenital Heart Disease, Comorbidities and Coexisting Conditions
2022-04-01
CompletedFeasibility Trial of a Mindfulness Based Intervention in Youth With Type 1 Diabetes
type1diabetes
N/A2022-03-31
RecruitingAdoptive T Lymphocyte Administration for Chronic Norovirus Treatment in Immunocompromised Hosts
Viral Infection, Hematopoietic Stem Cell Transplantation (HSCT), Primary Immunodeficiency Disorders (PID)
Phase 12022-03-17
RecruitingAugmented Reality Ultrasound Guidance
Paracentesis
N/A2022-03-11
CompletedNeoadjuvant Dual Checkpoint Inhibition and Cryoablation in Relapsed/Refractory Pediatric Solid Tumors
Osteosarcoma, Ewing Sarcoma, Rhabdomyosarcoma
Phase 22022-02-18
CompletedGroup Visits for High Risk Type 1 Diabetes (T1D)
Type 1 Diabetes
N/A2022-02-16
WithdrawnNerivio Device for Treatment of New Daily Headache Persistence (NDHP)
New Daily Persistent Headache (NDPH)
N/A2022-02-01
UnknownOnline Treatment Recovery Assistance for Concussion in Kids
Concussion, MTBI - Mild Traumatic Brain Injury
N/A2022-02-01
Active Not RecruitingResearch on Optimizing the Use of Technology With Education
Type 1 Diabetes, Continuous Glucose Monitoring, Behavioral Intervention
N/A2022-01-01
RecruitingMulti Tumor-Associated Antigen-Specific T Lymphocytes to Treat Patients With High Risk Solid Tumors
Solid Tumor
Phase 12021-11-17
CompletedDevelopment and Pilot Testing of a Novel Preschool Executive Function Curriculum
Executive Dysfunction
N/A2021-11-15
Active Not RecruitingIntervention-Induced Plasticity of Flexibility and Learning Mechanisms in ASD
Executive Dysfunction, Autism Spectrum Disorder, Adolescent Behavior
N/A2021-10-20
RecruitingT Cell Therapy Opposing Novel COVID-19 Infection in Immunocompromised Patients
SARS-CoV-2 Infection
Phase 12021-10-19
RecruitingPhysiologic Measure of VIPN
Chemotherapy-induced Peripheral Neuropathy
2021-09-20
CompletedA Hybrid Effectiveness-implementation Trial of a High School-based Executive Function Treatment for Autistic Y
Executive Dysfunction, Autism Spectrum Disorder, Adolescent Behavior
N/A2021-09-07
Active Not RecruitingPediatric COVID Outcomes Study (PECOS)
Covid19, MIS-C Associated with COVID-19, MIS-C Multisystem Inflammatory Syndrome in Children
2021-07-23
RecruitingDevelopment of a Therapeutic Endpoint in Pediatric Rheumatologic Conditions
Juvenile Idiopathic Arthritis, Systemic Lupus Erythematosus, Fibromyalgia
2021-07-16
CompletedFACE for Children With Rare Diseases
Rare Diseases
N/A2021-07-06
Active Not RecruitingCentral Blood Pressure and Pulse Wave Velocity in Kidney Transplant Recipients
End Stage Renal Disease
2021-07-01
CompletedHybrid Closed Loop in High Risk Youth With Type 1 Diabetes
Type 1 Diabetes
N/A2021-06-01
CompletedSound Levels in the Pediatric Cardiac Critical Care Unit and Their Correlation With Sedation Administration, D
Noise Exposure, Sedative Withdrawal Delirium, Sedative Toxicity
2021-03-01
UnknownTechnology-Enhanced Executive Functioning Intervention for ADHD
ADHD, Attention Deficit Hyperactivity Disorder, Attention Deficit Disorder
Phase 12021-02-03
Active Not RecruitingMR-HIFU Treatment of Painful Osteoid Osteoma
Osteoid Osteoma
Phase 22021-01-28
Enrolling By InvitationNeurodevelopmental Outcomes in ZIKV-Exposed Children
Zika Virus, Congenital Zika Syndrome, Congenital Infection
2020-11-23
UnknownComparative Study of the Sternal Patch System With a Conventional Holter Recorder
Cardiac Arrhythmia, Syncope
N/A2020-11-19
UnknownMetabolic Optimization Through Diet/Lifestyle Improvements For Youth
Dyslipidemias, Obesity
N/A2020-09-29
CompletedPreliminary Feasibility and Efficacy of Behavioral Intervention to Reduce Pain-Related Disability in Pediatric
Sickle Cell Disease, Pain
N/A2020-09-23
RecruitingSystemic Biomarkers of Brain Injury From Hyperammonemia
Urea Cycle Disorder, Organic Acidemia, Maple Syrup Urine Disease
2020-07-09
CompletedAccuracy of the Red Reflex Test in the Pediatric Population
Abnormal Vitreous Humor Morphology, Abnormal Choroid Morphology, Optic Nerve Diseases
2020-03-01
CompletedMRI to Predict Rejection and Failure in Transplant and Cardiomyopathy Patients
Heart Failure, Cardiac Imaging Techniques, Congenital Heart Defects
2019-12-10
CompletedConcussion Active Rehabilitation
Pediatric ALL, Concussion, Mild, Concussion, Brain
N/A2019-08-12
WithdrawnNear Infrared Spectroscopy in Sickle Cell Pediatric Patients
Sickle Cell Disease
2019-06-26
UnknownSingle Escalating Dose Pilot Trial of Canakinumab (ILARIS®) in Duchenne Muscular Dystrophy
Duchenne Muscular Dystrophy
Phase 1 / Phase 22019-05-01
CompletedFrameshift Peptides of Children With NF1
Neurofibromatosis Type 1
2019-04-11
CompletedIntermittent Hypoxia and Caffeine in Infants Born Preterm
Intermittent Hypoxia
Phase 22019-01-18
CompletedInfant Car Seat Use
Pediatric Car Seat Safety Training
N/A2018-12-31
UnknownImproving Health Communication During the Transition From Pediatric to Adult Diabetes Care
Type 1 Diabetes Mellitus
N/A2018-11-06
CompletedHydroxyurea and Transfusion
Sickle Cell Disease
Phase 22018-10-30
Active Not RecruitingWhole Body MRI to Identify Atypical Neurofibromas in Patients With NF1
Neurofibromatosis 1, Neurofibroma, Atypical Neurofibroma
N/A2018-07-12
UnknownDetermining the Impact of Penicillin in Latent RHD: The GOAL Trial
Rheumatic Heart Disease in Children, Latent Rheumatic Heart Disease, Rheumatic Heart Disease
Phase 22018-06-26
UnknownUltrasound for Scoliosis Diagnostic Evaluation
Scoliosis Idiopathic, Scoliosis; Juvenile
N/A2018-03-14
CompletedSocial Navigation for Adolescents in ED
Adolescent Behavior, Social Stress, Emergencies
N/A2017-08-01
WithdrawnClinical Impact of Rapid Prototyping 3D Models for Surgical Management
Double Outlet Right Ventricle, Transposition of the Great Arteries, Truncus Arteriosus
N/A2017-05-01
Active Not RecruitingT-Lymphocytes for Prevention or Treatment of Viral Infections Following Hematopoietic Stem Cell Transplantatio
Viral Infections, Bone Marrow Transplant Infection
Phase 12017-02-15
Active Not RecruitingResearch Study Utilizing Expanded Multi-antigen Specific Lymphocytes for the Treatment of Solid Tumors
Solid Tumors
Phase 12016-10-12
RecruitingNeuroimaging and Neuropsychological Outcomes in Urea Cycle Disorders
Urea Cycle Disorders
2016-08-01
SuspendedAcetaminophen Dosing in Obese Adolescents
Obesity, Childhood
Phase 32016-08-01
CompletedMental Health Care Coordination for Transition Aged Youth
Mental Health
N/A2016-04-01
CompletedFirst STEPS- Study of Type 1 in Early Childhood and Parenting Support
Diabetes Mellitus, Type 1
N/A2016-04-01
CompletedPCORI Urea Cycle Disorder Study
Urea Cycle Disorders
2016-03-04
CompletedGPS (Giving Parents Support): Parent Navigation After NICU Discharge
Premature Birth of Newborn, Family, Immature Newborn
N/A2016-01-01
CompletedThe Effects of Aromatherapy on the Incidence and Severity of Acute Pain
Venipuncture
N/A2015-11-01
WithdrawnEfficacy of Acetaminophen in Posterior Fossa Surgery
Arnold-Chiari Malformation, Posterior Fossa Tumors
Phase 22015-11-01
CompletedExecutive Function Intervention for High School Students With ASD
Autism Spectrum Disorder
N/A2015-07-11
CompletedSafety and Feasibility of MR-Guided High Intensity Focused Ultrasound (MR-HIFU) Ablation of Osteoid Osteoma in
Osteoid Osteoma
N/A2015-01-01
Active Not RecruitingEfficacy of Amicar for Children Having Craniofacial Surgery
Craniosynostosis
Phase 22014-10-01
CompletedImprovement of STI Detection in Adolescent Emergency Department Patients
Sexually Transmitted Infections
N/A2014-10-01
CompletedMRI Assessment of Arrythmia Ablation Lesions
Ventricular Tachycardia, Cardiac Arrhythmia
N/A2014-04-01
WithdrawnRisk-based Therapy for Sickle Cell Anemia: A Feasibility Study
Sickle Cell Anemia
Phase 22014-02-01
CompletedPilot Study of Cardiac MR in Patients With Muscular Dystrophy
Muscular Dystrophies, Cardiac Fibrosis, Genetic Diseases, Inborn
2014-01-01
CompletedPalliative Care in People Living With HIV/AIDS: Integrating Into Standard of Care
HIV
N/A2013-10-13
CompletedCytotoxic T Cells to Prevent Virus Infections
CMV, EBV, Adenovirus Infections
Phase 12013-09-01
CompletedImproving Pediatric Asthma Care Through Inhaled Steroids in Schools
Asthma
N/A2013-08-01
CompletedMyocardial Perfusion and Scarring in Adults With Congenital Heart Disease
Cardiac Disease
2013-07-01
CompletedComparison of Immunization Quality Improvement Dissemination Study
Immunization, DTaP Vaccine, Hepatitis B Vaccine
N/A2013-06-01
Active Not RecruitingTechnical Development for Pediatric Cardiovascular MRI
Congenital Heart Disease, Cardiovascular Disease
2013-05-01
CompletedBedside Lung Ultrasound in Young Children Presenting to the Emergency Department (ED) With Wheezing
Wheezing, Bronchiolitis
2012-10-01
CompletedFentanyl Metabolism in Obese Adolescents
Morbid Obesity
2011-09-01
WithdrawnNeuroimaging and Neurocognitive Assessment and Response to Sapropterin Dihydrochloride Treatment in Phenylketo
PKU
N/A2011-04-01
RecruitingMolecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem Glioma
Diffuse Intrinsic Pontine Glioma, Brainstem Glioma
2010-04-01
CompletedOral Galactose in Children With Steroid Resistant Nephrotic Syndrome
Focal Segmental Glomerulosclerosis, Steroid Resistant Nephrotic Syndrome
N/A2009-10-01
UnknownMechanisms of Sleep Disturbance in Children With Generalized Anxiety Disorder (GAD)
Generalized Anxiety Disorder, Sleep Disturbances
2009-08-01
CompletedImproving Asthma Care Through Parental Empowerment
Asthma
N/A2009-01-01
CompletedClinical Performance Evaluation of Pediatric and Neonatal Low Saturation Oximetry Sensors
Low Oxygen Saturation
2009-01-01
CompletedMagnetic Resonance Imaging (MRI) of Appendicitis in Children
Appendicitis
N/A2008-08-01
CompletedThe Pharmacology and Hemodynamics of Dexmedetomidine in Children With Congenital Heart Disease
Cardiac Transplant, Patent Ductus Arterious, Atrial Septal Defect
Phase 32006-12-01
WithdrawnAssessment of Opioid Analgesia in Sickle Cell
Sickle Cell Disease
Phase 42006-11-01
CompletedDexmedetomidine vs Fentanyl for BMT
Otitis
Phase 42005-08-01
CompletedUse of Sustained Release Antiepileptic Medication (Depakote® ER) for Pediatric Epilepsy in a Mental Retardatio
Epilepsy, Mental Retardation, Developmental Disabilities
Phase 42005-08-01
CompletedDexmedetomidine for Immediate Perioperative Analgesia in Pediatric Patients Undergoing Tonsillectomy
Tonsillitis
Phase 42005-01-01
TerminatedOptimizing Antiretroviral Therapy in HIV-Infected Children and Adolescents
HIV Infections
2004-11-01
CompletedPrevalence of Proteinuria and Chronic Kidney Disease in Pediatric HIV-Infected Patients
Chronic Kidney Failure, AIDS-Associated Nephropathy, HIV Infections
2004-09-01
CompletedPharmacokinetics, Safety and Tolerability of Zavesca (Miglustat) in Patients With Infantile Onset Gangliosidos
GM2 Gangliosidoses, Tay-Sachs, Sandhoff Disease
Phase 32004-07-01