| Recruiting | Diagnostic Accuracy of SleepImage Technology for Detecting Respiratory Failure in Patients With Amyotrophic La Amyotrophic Lateral Sclerosis | — | 2026-03-24 |
| Recruiting | Corticosteroid Tapering in Sarcoidosis Sarcoidosis | N/A | 2026-03-19 |
| Not Yet Recruiting | A Prospective Study of Advanced Diagnostics in People With an Unclear Diagnosis of Cystic Fibrosis Cystic Fibrosis (CF), CFTR-related Disorders | — | 2026-02-02 |
| Not Yet Recruiting | Precision Detection and Prediction of Atrial Arrhythmias Using Artificial Intelligence and Consumer Wearable D Atrial Fibrillation (AF) | — | 2025-12-01 |
| Recruiting | Identifying the Optimal IMT Dose in ICU Difficult to Wean, Mechanically Ventilated Patients With a Tracheostomy | — | 2025-11-23 |
| Recruiting | A Pilot Study to Assess Body Mass Composition Measurement Using BIA and Muscle Ultrasound in IPF and PPF Patie Idiopathic Pulmonary Fibrosis (IPF), Progressive Pulmonary Fibrosis | — | 2025-09-09 |
| Recruiting | A Study of Females With CF Throughout Pregnancy and Post-partum, and Follow up of Their Offspring Cystic Fibrosis (CF), Pregnancy, Infant, Newborn | — | 2025-06-12 |
| Recruiting | AVEIR™ Leadless Pacemaker (LP) United Kingdom (UK) Registry Bradycardia, Atrio-Ventricular Block, Syncope | — | 2025-04-15 |
| Recruiting | Evaluation of Exercise Testing and Physical Activity in Children and Adolescents Living With Inherited Arrhyth Long QT Syndrome, Catecholaminergic Polymorphic Ventricular Tachycardia Type 1, Catecholaminergic Polymorphic Ventricular Tachycardia Type 2 | — | 2025-03-18 |
| Enrolling By Invitation | Chest CT Biomarkers as Prognostic Predictors in SSc-ILD Systemic Sclerosis | — | 2024-11-01 |
| Not Yet Recruiting | A Pilot Study Evaluating the Potential of 18F Fluorodeoxyglucose PET-CT Imaging in Diagnosing Cardiac Rejectio Cardiac Transplant Rejection | N/A | 2024-09-30 |
| Not Yet Recruiting | Coronary Artery Disease in Hearts Donated for Transplantation Heart Failure | — | 2024-09-01 |
| Recruiting | A Prospective, Observational, Single Centre Study to Assess the Feasibility of the Data Harvested by the Acora Heart Failure, Decompensated Heart Failure | — | 2024-04-29 |
| Active Not Recruiting | YOGA-CF (Yoga Outcomes Get Assessed in Cystic Fibrosis) Cystic Fibrosis | N/A | 2024-04-22 |
| Unknown | Computational Assessment of Bioprosthetic Aortic Valve Function CFD, Valve Heart Disease | — | 2024-04-01 |
| Unknown | Cardiac Cachexia in Advanced Heart Failure Advanced Heart Failure, Cardiac Cachexia, Weight Loss | — | 2024-01-25 |
| Recruiting | Trans-coronary Cooling and Dilution for Cardioprotection During Revascularisation for ST-elevation Myocardial Myocardial Infarction, Reperfusion Injury, Myocardial | N/A | 2023-11-01 |
| Unknown | Spirometry Interpretation Performance of Primary Care Clinicians With/Without AI Software Lung Disease | N/A | 2023-06-27 |
| Completed | Specialist Dietetic Intervention in Malnourished Patients with Fibrotic ILD: a Randomised Controlled Pilot Tri Interstitial Lung Disease | N/A | 2023-06-20 |
| Unknown | AI in PRImary Care Spirometry Pathways for Diagnosis of Lung Disease (APRIL) Lung Diseases | N/A | 2023-06-03 |
| Completed | Reducing Oxygen Consumption in Critical Care Mechanical Ventilation Complication | — | 2023-05-25 |
| Completed | Reproducibility of Virtual Exercise Assessments Versus Face-to-face Exercise Testing in Adults With Cystic Fib Cystic Fibrosis | N/A | 2023-05-01 |
| Unknown | Connecting Breath and Mind for CYP With Long COVID Post-COVID-19 Syndrome, Anxiety, Breathlessness | N/A | 2023-04-30 |
| Unknown | HDM and Silver Birch NAC Standardisation Allergic Rhinitis | N/A | 2022-09-22 |
| Active Not Recruiting | Validation of an Artificial Intelligence Enabled Diagnostic Support Software (ArtiQ.Spiro) in Primary Care Spi Respiratory Disease | — | 2022-07-01 |
| Completed | DIGITAL-HF - Digital Tools in Heart Failure - a Survey of Patient Usage (DIGITAL-HF) Heart Failure | — | 2022-01-04 |
| Unknown | Individualised Mapping in Persistent AF Ablation Persistent Atrial Fibrillation | N/A | 2021-11-01 |
| Completed | Metabolic Cost of IMT Mechanical Ventilation Complication | — | 2021-10-18 |
| Completed | The Sunrise OSA Trial Obstructive Sleep Apnea | N/A | 2021-08-21 |
| Unknown | 4D Motion of the Aorta in the Chest and Simulated Wall Stress Distribution in Relation to Aortic Events Aortic Dissection | N/A | 2021-08-01 |
| Unknown | Substrate Guided Ablation Therapy for Atrial Fibrillation Persistent Atrial Fibrillation | — | 2021-01-01 |
| Completed | Morphine Sulfate/Placebo for the Treatment of PulmonAry Fibrosis Cough Idiopathic Pulmonary Fibrosis | Phase 3 | 2020-12-17 |
| Completed | Reliability and Validity of iOS in IPF Idiopathic Pulmonary Fibrosis | — | 2020-11-06 |
| Active Not Recruiting | Changes in iOS in IPF Idiopathic Pulmonary Fibrosis | — | 2020-11-06 |
| Completed | Perceptions of the Clinical and Psychosocial Impact of Covid-19 in Patients With NMD Neuromuscular Diseases, Neurological Diseases or Conditions | — | 2020-09-11 |
| Completed | Remote Monitoring of AF Recurrence Using mHealth Technology Long Standing Persistent Atrial Fibrillation | — | 2020-08-01 |
| Unknown | EBUS-TBNA vs Acquire TBNB Mediastinal Lymphadenopathy | N/A | 2020-03-02 |
| Completed | Long-term Outcomes in Long Standing Persistent Atrial Fibrillation Long Standing Persistent Atrial Fibrillation | — | 2020-02-01 |
| Recruiting | The Harefield Acute Myocardial Infarction Cohort Acute Coronary Syndrome | — | 2020-01-09 |
| Completed | Mindfulness in Chest Pain - a Feasibility Randomized Controlled Study Chest Pain | N/A | 2019-12-01 |
| Completed | The POSA Trial - Positional Therapy for Positional OSA Sleep Apnea, Obstructive, Positional Sleep Apnea | N/A | 2019-10-30 |
| Completed | Multisystem and Autonomic Complications of NMD on Long-term NIV Neuromuscular Diseases, Neurologic Disorder | — | 2019-10-25 |
| Unknown | HCM-AF Ablation With ACUTUS Atrial Fibrillation, Hypertrophic Cardiomyopathy | N/A | 2019-10-01 |
| Terminated | SPOT-FRAILTY Assessment of Frailty in Patients Over the Age of 70 Undergoing a Cardiac Intervention Frailty | — | 2019-08-19 |
| Unknown | VIVO Mapping Protocol Ventricular Tachycardia, Ventricular Ectopic Beat(S) | N/A | 2019-06-01 |
| Unknown | Evaluation of Speckle Tracking Parameters as Predictors of Successful VA SPECKLE ECMO Cardiogenic Shock | — | 2018-11-28 |
| Unknown | Novel Quantitative Magnetic Resonance Imaging (MRI) Measures in the Assessment and Follow-up of Patients With Pulmonary Hypertension | N/A | 2018-11-19 |
| Completed | Muscle Stimulation in Advanced Idiopathic Pulmonary Fibrosis Idiopathic Pulmonary Fibrosis | N/A | 2018-10-15 |
| Unknown | Non-fluoroscopy Ablation of AF/AT AF - Atrial Fibrillation, Atrial Tachycardia | N/A | 2018-10-08 |
| Unknown | Weaning Algorithm for Mechanical VEntilation Respiration, Artificial, Critical Care, Respiratory Insufficiency | N/A | 2018-09-24 |
| Unknown | Does Extra-Corporeal Membrane Oxygenation Alter Antiinfectives Therapy Pharmacokinetics in Critically Ill Pati Critical Illness, Extracorporeal Membrane Oxygenation Complication, Infection | — | 2018-09-03 |
| Unknown | Ballooned Intercostal Drain Trial Pleural Effusion, Pneumothorax | N/A | 2018-03-07 |
| Completed | A Study of Web and Tablet-based Interactive Audiometry in Adults With CF Hearing Loss, Sensorineural, Cystic Fibrosis | — | 2018-03-01 |
| Unknown | LVR in Severe Emphysema Using Bronchoscopic Autologous Blood Instillation in Combination With Intra-bronchial Chronic Obstructive Pulmonary Disease, Emphysema | N/A | 2017-08-24 |
| Unknown | MRI in Cystic Fibrosis and Primary Ciliary Dyskinesia Cystic Fibrosis, Primary Ciliary Dyskinesia | — | 2017-05-05 |
| Unknown | Iron and Chronic Obstructive Pulmonary Disease (COPD) Exercise Trial Chronic Obstructive Pulmonary Disease | Phase 2 | 2017-04-01 |
| Unknown | Studying the Airway Microenvironment in Patients Undergoing Surgical and Bronchoscopic Interventions for COPD Chronic Obstructive Pulmonary Disease, Emphysema, Chronic Bronchitis | — | 2017-02-06 |
| Unknown | Lung Volume Reduction Coil Microbiome Study Chronic Obstructive Pulmonary Disease, Emphysema | — | 2017-01-30 |
| Completed | Improving Outcome Measures For Adult CF ACT Trials Cystic Fibrosis | N/A | 2016-09-01 |
| Unknown | Families' Experiences of Paediatric ICC Diagnosis Inherited Cardiac Conditions | N/A | 2016-06-01 |
| Completed | Does Cardiac REhabilitation Improve Functional, Independence, Frailty and Emotional outCOmes Following Trans C Aortic Stenosis | N/A | 2016-05-01 |
| Completed | EBUS-TBNA vs Flex 19G EBUS-TBNA Lymphadenopathy, Lung Cancer, Sarcoidosis | N/A | 2016-05-01 |
| Unknown | A Pilot Feasibility Study in Recovered Heart Failure Heart Failure | Phase 4 | 2016-04-01 |
| Unknown | Intrinsic PEEP and Laryngeal Aperture in COPD Chronic Obstructive Pulmonary Disease | — | 2016-04-01 |
| Completed | a-Klotho in Relation to Calcification in the Coronary Arteries and Aortic Valve in Patients With Chronic Kidne Vascular Calcification, Chronic Kidney Diseases | — | 2016-01-15 |
| Unknown | Prevalence of Pompe's Disease in Respiratory Clinics Pompe's Disease | — | 2015-09-01 |
| Unknown | Catheter Ablation Versus Thoracoscopic Surgical Ablation in Long Standing Persistent Atrial Fibrillation (CASA Persistent Atrial Fibrillation | N/A | 2015-06-01 |
| Unknown | Mesothelioma and Radical Surgery 2 Mesothelioma | N/A | 2015-05-01 |
| Completed | The Predictive Ability of 4MGS in IPF Idiopathic Pulmonary Fibrosis | — | 2015-03-01 |
| Completed | Responsiveness and MID of 4 Metre Gait Speed in Idiopathic Pulmonary Fibrosis Idiopathic Pulmonary Fibrosis | — | 2015-02-01 |
| Completed | Reliability of the 4 Metre Gait Speed in Idiopathic Pulmonary Fibrosis Idiopathic Pulmonary Fibrosis | — | 2015-02-01 |
| Completed | Rituximab Versus Cyclophosphamide in Connective Tissue Disease-ILD Interstitial Lung Disease, Scleroderma, Idiopathic Inflammatory Myositis | Phase 2 / Phase 3 | 2014-11-01 |
| Completed | A Pilot Study of Transcoronary Myocardial Cooling Acute Myocardial Infarction | N/A | 2014-09-01 |
| Completed | Ambulatory Oxygen in Fibrotic Lung Disease (FLD) (AmbOx) Lung; Disease, Fibroid (Chronic) | Phase 4 | 2014-08-01 |
| Terminated | A Pilot Study Into Health Pre and Post Treatment With Intravenous Aminophylline and Hydrocortisone in Severe A Asthma | — | 2014-06-01 |
| Suspended | The Effect of CRT on the Hypercapnic Ventilatory Response Sleep Disordered Breathing, Heart Failure | — | 2014-06-01 |
| Withdrawn | EBUS-TBNA Versus EBUS-TBNB Mediastinal Lymphadenopathy, Hilar Lymphadenopathy, Carcinoma | N/A | 2014-05-01 |
| Unknown | The Effect of Two Weeks of Voluntary Reduced Physical Activity in Chronic Obstructive Pulmonary Disease (COPD) Chronic Obstructive Pulmonary Disease (COPD), Muscle Atrophy | N/A | 2014-05-01 |
| Unknown | LV Endocardial Cardiac Resynchronisation Therapy Heart Failure | N/A | 2014-04-01 |
| Unknown | Validation of the ApneaScan Algorithm in Sleep Disordered Breathing Sleep-Disordered Breathing, Heart Failure | — | 2014-03-01 |
| Unknown | The Role of Gastroesophageal Reflux in Scleroderma Pulmonary Fibrosis Interstitial Lung Disease, Systemic Sclerosis, Gastroesophageal Reflux | — | 2014-02-01 |
| Terminated | Post-hospitalisation Nutritional Support and Gait Speed in COPD Pulmonary Disease, Chronic Obstructive, Respiratory Tract Diseases, Lung Diseases, Obstructive | Phase 3 | 2014-01-01 |
| Completed | Is Gait Speed and Sarcopenia Prognostic in Chronic Respiratory Disease? Chronic Obstructive Pulmonary Disease and Allied Conditions | — | 2013-12-01 |
| Completed | Is the 4MGS a Useful Outcome Measure Post-PPCI Acute Myocardial Infarction | — | 2013-12-01 |
| Completed | Electronic Hand Hygiene Monitoring and ICU Infection Rates Cross Infection | — | 2013-11-01 |
| Unknown | Oral Verses Patch Trial In Menopausal Women - Individualisation of Oestrogen Therapy Venous Thrombosis, Insulin Resistance | Phase 4 | 2013-11-01 |
| Terminated | The Addition of Non-Invasive Ventilation To Airway Clearance Techniques In Adults With Cystic Fibrosis Cystic Fibrosis | N/A | 2013-07-01 |
| Unknown | Left Atrial Appendage Electrical Isolation and Occlusion to Treat Persistent Atrial Fibrillation: A Safety and Persistent Atrial Fibrillation | N/A | 2013-07-01 |
| Completed | Comparing Laboratory Blood Glucose Results With HemoCue Glucose 201 RT Cystic Fibrosis | — | 2013-06-01 |
| Terminated | Partial Left Ventricular Support in Advanced Heart Failure Heart Failure, Heart-Assist Devices | — | 2013-06-01 |
| Completed | Renal Denervation in Heart Failure With Preserved Ejection Fraction Cardiac Failure | Phase 2 | 2013-04-01 |
| Withdrawn | A Comparison of Advanced Imaging Techniques in Aortic Stenosis Aortic Stenosis | — | 2013-01-01 |
| Completed | Physical Activity Augmentation Using Pedometers During Pulmonary Rehabilitation in Chronic Obstructive Pulmona Lung Diseases, Obstructive, Pulmonary Disease, Chronic Obstructive, Bronchitis, Chronic | N/A | 2012-07-01 |
| Unknown | Contact Force Sensing Use in Atrial Fibrillation Ablation Atrial Fibrillation | N/A | 2012-05-01 |
| Completed | IPF Drug Deposition Study Idiopathic Pulmonary Fibrosis | Phase 1 | 2012-04-01 |
| Completed | What is an Important Change in the Short Physical Performance Battery (SPPB)? Respiratory Tract Diseases, Lung Diseases | — | 2012-03-01 |
| Terminated | Evaluating Additional Platelet Inhibition in Patients With High Platelet Reactivity Undergoing Percutaneous Co Cardiovascular Disease, Acute Coronary Syndrome | Phase 4 | 2012-02-01 |
| Unknown | Fibre Specific Signalling in the Locomotor Myopathy of Chronic Obstructive Pulmonary Disease Chronic Obstructive Pulmonary Disease | — | 2011-12-01 |
| Completed | Do the SPPB and 4-metre Gait Speed Predict Hospital Readmission in Patients Hospitalised for Acute Exacerbatio Pulmonary Disease, Chronic Obstructive, Respiratory Tract Diseases, Lung Diseases | — | 2011-11-01 |
| Unknown | Cardiac Magnetic Resonance Imaging Guided Left Ventricular Lead Placement Heart Failure | Phase 3 | 2011-08-01 |
| Completed | CT Calcium Scoring in Suspected Stable Angina Coronary Disease | — | 2011-06-01 |
| Completed | Is the Short Physical Performance Battery a Useful Outcome Measure in Chronic Obstructive Pulmonary Disease Pulmonary Disease, Chronic Obstructive, Lung Diseases, Obstructive, Pulmonary Emphysema | — | 2011-04-01 |
| Unknown | Catheter Versus Thoracoscopic Surgical Ablation Strategy in Persistent Atrial Fibrillation Persistent Atrial Fibrillation | N/A | 2011-04-01 |
| Terminated | Direct Angioplasty for Non ST Elevation Acute Coronary Events: DANCE Pilot Study Acute Coronary Syndrome | N/A | 2010-10-01 |
| Completed | Prospective Observation of Fibrosis in the Lung Clinical Endpoints Study Idiopathic Pulmonary Fibrosis, Idiopathic Non-specific Interstitial Pneumonitis | — | 2010-09-01 |
| Completed | A Study to Examine the Implantation Characteristics of Two Drug-Eluting Stents Coronary Artery Disease | N/A | 2010-09-01 |
| Completed | Implementation of Telemonitoring in Chronic Heart or Lung Failure COPD, Heart Failure, Respiratory Failure | Phase 1 | 2010-06-01 |
| Unknown | Early Percutaneous Coronary Intervention (PCI) After Fibrinolysis Versus Standard Therapy in ST Segment Elevat Myocardial Infarction | — | 2009-11-01 |
| Withdrawn | Dysfunctional Breathing in Difficult Asthma. Asthma | — | 2009-10-01 |
| Completed | Minimally Invasive Endoscopy in Diffuse Lung Disease Lung Disease, Lung Cancer | N/A | 2009-06-01 |
| Completed | Catheter Ablation Versus Medical Rate Control for Atrial Fibrillation in Patients With Heart Failure Atrial Fibrillation, Heart Failure | N/A | 2009-04-01 |
| Completed | Use of Endobronchial Valves in Non-Upper Lobe Heterogeneous Emphysema Heterogeneous Emphysema | Phase 3 | 2009-01-01 |
| Withdrawn | Renal Function in Adults With Congenital Heart Disease. Cardiovascular Abnormalities, Kidney Failure | — | 2008-09-01 |
| Unknown | Collaborative Systematic Overview of Randomised Controlled Trials of Beta-Blockers in the Treatment of Heart F Heart Failure | — | 2008-08-01 |
| Completed | Do Physiotherapy Techniques Improve Posture During Admission for a Chest Infection in Adults With Cystic Fibro Cystic Fibrosis | N/A | 2008-06-01 |
| Unknown | Bosentan in Pulmonary Hypertension in Interstitial Lung Disease Treatment Study Pulmonary Hypertension, Interstitial Lung Disease, Idiopathic Pulmonary Fibrosis | Phase 4 | 2008-04-01 |
| Completed | Mortality Post-TAVI and Correlation With Haemodynamic Parameters. Aortic Valve Stenosis | — | 2008-01-01 |
| Completed | CMR to Assess Fibrosis in Cardiomyopathy Using Eplerenone Cardiomyopathy | Phase 4 | 2007-12-01 |
| Unknown | European Quality Improvement Programme for Acute Coronary Syndromes Acute Coronary Syndrome | N/A | 2007-08-01 |
| Unknown | Physiotherapy and Dysfunctional Breathing Hyperventilation | Phase 3 | 2007-07-01 |
| Completed | Do Musculoskeletal Techniques Improve Forced Expiratory Volume in One Second in Adults With Cystic Fibrosis? Cystic Fibrosis | N/A | 2007-03-01 |
| Completed | Airway Clearance Using High Frequency Chest Wall Oscillation Cystic Fibrosis | Phase 3 | 2007-01-01 |
| Terminated | Sequestration of Platelets Prior to Bypass Reduces Bleeding After Cardiac Surgery Cardiac Surgical Procedures, Cardiopulmonary Bypass, Blood Platelet Disorders | Phase 2 | 2006-08-01 |
| Completed | BioGlue or Vivostat in the Control of Air Leak in Thoracic Surgery Thoracic Surgery, Air Leak | N/A | 2005-12-01 |
| Completed | The Use of Inflammatory Markers to Guide Therapy in Children With Severe Asthma Asthma | N/A | 2005-12-01 |
| Completed | The Diagnosis of Oral Allergy Syndrome Through the Use of a Structured Questionnaire Food Allergy | — | 2005-05-01 |
| Unknown | Assessment of Heart and Heart-Lung Transplant Patient Outcomes Following Pulmonary Rehabilitation Emphysema, Alveolitis, Fibrosing, Cystic Fibrosis | Phase 1 | 2004-09-01 |
| Unknown | Combined Chelation Treatment With Deferiprone and Deferoxamine in Thalassemia Major Beta-Thalassemia | Phase 4 | 2004-05-01 |
| Completed | Prospective Registry of Outcomes and Management of Acute Ischaemic Syndromes Acute Coronary Syndromes, Coronary Artery Disease | N/A | 2004-03-01 |
| Unknown | The Early High Risk Period for Patients With Heart Failure Heart Failure, Congestive | — | 2004-01-01 |
| Completed | Role of Routine on-Table Cholangiography in Laparoscopic Cholecystectomy Common Bile Duct Stones | N/A | 2003-06-01 |
| Completed | Programme to Optimise Risk Factors in Patients Waiting for Coronary Artery Bypass Surgery Coronary Artery Disease | Phase 2 / Phase 3 | 2003-01-01 |
| Unknown | Rosiglitazone Plaque Study Diabetes Mellitus, Type 2, Vascular Diseases, Hypertension | Phase 3 | 2002-10-01 |
| Completed | Oral Allergy Syndrome (OAS): a Pilot Study to Evaluate a Clinical Questionnaire as a Diagnostic Tool Rhinitis, Food Allergy | — | 2002-07-01 |
| Completed | Cystic Fibrosis Withdrawal of Inhaled Steroids Evaluation Study (CF WISE Study) Cystic Fibrosis | N/A | 2001-05-01 |
| Unknown | The Prognostic Significance of Fibrosis Detection in Cardiomyopathy Cardiomyopathy, Coronary Artery Disease | — | 2000-01-01 |
| Completed | Should Any One Airway Clearance Technique be Recommended for People With Cystic Fibrosis? Cystic Fibrosis | Phase 4 | 1999-07-01 |
| Completed | The Stent or Surgery (SoS) Trial Coronary Artery Disease | N/A | 1996-11-01 |