NCT01467635

EBUS-TBNA Versus EBUS-TBNB

Endobronchial Ultrasound Transbronchial Needle Aspiration (EBUS-TBNA) Versus Endobronchial Ultrasound Transbronchial Needle Biopsy (EBUS-TBNB) in the Assessment of Mediastinal and Hilar Lymphadenopathy: a Randomised Trial

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Royal Brompton & Harefield NHS Foundation Trust · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

A prospective diagnostic clinical study randomising patients undergoing endobronchial ultrasound guided transbronchial needle aspiration (EBUS-TBNA) of enlarged mediastinal and hilar lymph nodes to have sampling using the usual EBUS-TBNA needle or a novel biopsy forceps (EBUS-TBNB). The study aims to establish whether the use of EBUS-TBNB can significantly increase the diagnostic yield over EBUS-TBNA, without an increase in complication rates.

Conditions

• Mediastinal Lymphadenopathy
• Hilar Lymphadenopathy
• Carcinoma
• Lymphoma
• Sarcoidosis
• Mycobacterial Disease

Interventions

Type	Name	Description
DEVICE	Endobronchial ultrasound guided lymph node sampling	Patients with enlarged mediastinal or hilar lymph nodes have these sampled under endobronchial ultrasound guidance using either the EBUS-TBNA needle or the EBUS-TBNB biopsy forceps.

Timeline

• Start date: 2014-05-01
• Primary completion: 2016-07-01
• Completion: 2016-07-01
• First posted: 2011-11-09
• Last updated: 2016-07-13

Locations

3 sites across 2 countries: Germany, United Kingdom