NCT06182956

NIV Versus HFO for Acute Exacerbations of Interstitial Lung Diseases

Evaluation of Physiological Effects of Noninvasive Mechanical Ventilation and High-flow Oxygen Therapy for Acute Exacerbations of Interstitial Lung Diseases

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 18 (estimated)
• Sponsor: ADIR Association · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The objectives of this study are to compare the physiological consequences of high-flow oxygen therapy and noninvasive mechanical ventilation on ventilation, respiratory work and hemodynamics during acute respiratory failure in diffuse interstitial pneumonia.

Conditions

• Interstitial Lung Disease
• Acute Respiratory Failure

Interventions

Type	Name	Description
DEVICE	Noninvasive mechanical ventilation	Noninvasive mechanical ventilation is a respiratory technique which allows the administration of positive inspiratory and expiratory airway pressures in order to ventilate the lungs.
DEVICE	Nasal high-flow oxygen therapy	Nasal high-flow is a respiratory technique which allows the administration of warmed and humidified air, associated with oxygen.
DEVICE	Continuous positive airway pressure	Continuous positive airway pressure is a respiratory technique which allows to maintain a constant positive airway pressure during inspiration and expiration.

Timeline

• Start date: 2024-01-01
• Primary completion: 2026-12-31
• Completion: 2026-12-31
• First posted: 2023-12-27
• Last updated: 2023-12-27

Locations

1 site across 1 country: France