| Not Yet Recruiting | Chronic COUGH Management in Interstitial Lung DisEase NCT06782893 | Aveiro University | N/A |
| Not Yet Recruiting | Immunomodulatory Treatment of Interstitial Lung Disease Associated With Surfactant Related Gene Variants NCT07443436 | Assistance Publique - Hôpitaux de Paris | Phase 2 |
| Not Yet Recruiting | Titrated Ambulatory Oxygen in Fibrotic ILD and COPD With Isolated Exertional Hypoxemia NCT07512687 | State University of New York at Buffalo | N/A |
| Not Yet Recruiting | Emapalumab MDA5 Rapidly Progressive Interstitial Lung Disease (RP-ILD) Study NCT07486869 | University of Miami | Phase 2 |
| Recruiting | Effects of Oxygen Supplementation During the 6-Minute Walk Test in Chronic Respiratory Failure or Exertional H NCT07451977 | Istituti Clinici Scientifici Maugeri SpA | N/A |
| Not Yet Recruiting | An Open-Label Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary NCT07234032 | Insmed Incorporated | Phase 3 |
| Not Yet Recruiting | Clinical Study on the Application of PET Probes Targeting DDR2 in the Diagnosis of Interstitial Lung Disease W NCT07459179 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | — |
| Withdrawn | Lung Cancer Screening CT for Firefighters NCT06836414 | University of California, San Francisco | N/A |
| Recruiting | Impact of Capillaroscopy in the Investigation of Diffuse Interstitial Pneumonias NCT07283081 | University Hospital, Bordeaux | N/A |
| Recruiting | Exploration of Metabolome in Patients With Interstitial Lung Disease and Pulmonary Hypertension With or Withou NCT07254338 | Hospices Civils de Lyon | — |
| Not Yet Recruiting | The Effect of Video Game-Based Exercise Training in Patients With Interstitial Lung Disease NCT07167238 | Istinye University | N/A |
| Recruiting | SUPPORT-T in Patients With Progressive Pulmonary Fibrosis and Their Caregivers NCT07269262 | Medical University of South Carolina | N/A |
| Recruiting | Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hyp NCT07179380 | Insmed Incorporated | Phase 3 |
| Recruiting | A Study of BIO 300 and Thoracic Radiation Therapy in People With Non-Small Cell Lung Cancer and Interstitial L NCT07323732 | Memorial Sloan Kettering Cancer Center | Phase 2 |
| Not Yet Recruiting | MOBoxy: MoblO2 to Maintain Oxygenation NCT07222592 | National Jewish Health | N/A |
| Recruiting | Generative AI Impact on Rheumatoid Arthritis Complications Diagnosis NCT07301892 | Guang'anmen Hospital of China Academy of Chinese Medical Sciences | — |
| Not Yet Recruiting | Novel Biomarkers in Assessment of Interstitial Lung Disease Associated With Rheumatoid Arthritis Patients NCT07003451 | Assiut University | — |
| Not Yet Recruiting | Human Umbilical Cord Mesenchymal Stem Cell Injection for the Treatment of Interstitial Lung Disease NCT06534528 | Shanghai Life Science & Technology | Phase 1 |
| Recruiting | Effects of Telitacicept vs Cyclophosphamide on Lupus Related Interstitial Lung Disease NCT07077486 | Tongji Hospital | Phase 4 |
| Recruiting | Study of the Efficacy of Nintedanib+Tocilizumab in Patients With Systemic Sclerosis and Interstitial Lung Dise NCT06297096 | National Institute of Geriatrics, Rheumatology and Rehabilitation, Poland | Phase 3 |
| Recruiting | Evaluation of the Reproducibility of the Automated Measurement of the Extent of ILD on Chest CT NCT06743022 | Assistance Publique - Hôpitaux de Paris | N/A |
| Not Yet Recruiting | Interpretation of the Role of Eosinophils in Diffuse Interstitial Pneumopathies NCT06980844 | Hopital Foch | N/A |
| Completed | Impact of Lung Boost Device on Ventilatory Functions and Fatigue in Patients With Interstitial Lung Diseases NCT06991153 | Cairo University | N/A |
| Recruiting | H01 in Adults With Interstitial Lung Disease (The SOLIS Study) NCT06325696 | National Institute of Environmental Health Sciences (NIEHS) | Phase 2 |
| Recruiting | PRospective phenotypIng and Multi-omic Endotyping of Progressive Pulmonary Fibrosis NCT06855329 | University of Massachusetts, Worcester | — |
| Not Yet Recruiting | Continuous Versus Demand-Based Oxygen in Patients With Fibrotic Interstitial Lung Disease and Chronic Obstruct NCT06767904 | Sissel Kronborg-White | N/A |
| Recruiting | DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lun NCT06388421 | United Therapeutics | — |
| Recruiting | Reducing Respiratory Symptoms of Pulmonary Irradiation in Interstitial Lung Disease NCT05986318 | David Palma | Phase 2 |
| Recruiting | dEtection of rheumAtoid aRthritis - Interstitial Lung dIseasE by Thoracic ultRasound NCT06235645 | University Hospital, Tours | — |
| Recruiting | P4O2 ILD Extension NCT06644144 | Amsterdam UMC, location VUmc | — |
| Active Not Recruiting | A Study of Mosliciguat in PH-ILD NCT06635850 | Pulmovant, Inc. | Phase 2 |
| Recruiting | A Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of the Efficacy and Safety of Qifangfeixian NCT06674148 | Huilan Zhang | Phase 2 / Phase 3 |
| Recruiting | Evaluation of the Effectiveness, Safety, and Cost of a Smart Home-based Hospital System for Patients With Inte NCT06601790 | Yonsei University | N/A |
| Not Yet Recruiting | Pilot Study of Nitrate-rich Beetroot Juice Supplementation in Patients With Idiopathic Pulmonary Fibrosis (IPF NCT06488638 | University Hospital Southampton NHS Foundation Trust | N/A |
| Recruiting | Hydroxychloroquine in Children's Interstitial Lung Diseases With Genetic Causes NCT04532346 | Children's Hospital of Fudan University | EARLY_Phase 1 |
| Recruiting | Mycophenolate Mofetil in Systemic Sclerosis With Subclinical Interstitial Lung Disease NCT05785065 | Centre hospitalier de l'Université de Montréal (CHUM) | Phase 2 |
| Recruiting | ADSCs Therapy in Patients With CTD-ILD NCT06574581 | China Medical University Hospital | Phase 1 / Phase 2 |
| Recruiting | Skeletal Muscle Function in Interstitial Lung Disease NCT03800017 | University of British Columbia | N/A |
| Recruiting | Effects of Drinking Beetroot Juice on Exercise Performance in Patients With Fibrotic Interstitial Lung Disease NCT04299945 | University of British Columbia | N/A |
| Recruiting | Reducing Chronic Breathlessness in Adults by Following a Self-guided, Internet Based Supportive Intervention ( NCT06326957 | King's College Hospital NHS Trust | N/A |
| Not Yet Recruiting | FIBRotic Interstitial Lung Disease With Nocturnal hypOXaemia and EXercise Induced desaTuRAtion NCT06416163 | Guy's and St Thomas' NHS Foundation Trust | — |
| Recruiting | Identification of Multiple Pulmonary Diseases Using Volatile Organic Compounds Biomarkers in Human Exhaled Bre NCT06528418 | ChromX Health | — |
| Recruiting | Effect of HIgh-flow Therapy in Long-term Oxygen Therapy NCT06247397 | Skane University Hospital | N/A |
| Completed | Effect of Pulmonary Telerehabilitation and Telemonitoring for Patients With Chronic Respiratory Diseases NCT05824910 | University of Manitoba | N/A |
| Recruiting | The Effect of Exercise Training on lncRNA Expression in Rheumatoid Arthritis NCT07320846 | Saglik Bilimleri Universitesi | N/A |
| Recruiting | REspiratory diSEAse cohoRt Studies of CHinese Medicine for ILD (RESEARCH-ILD) NCT06577753 | Henan University of Traditional Chinese Medicine | — |
| Recruiting | A Study Evaluating the Safety and Efficacy of Inhaled AP01 in Participants With Progressive Pulmonary Fibrosis NCT06329401 | Avalyn Pharma Inc. | Phase 2 |
| Recruiting | Patients With Interstitial Lung Disease NCT06645977 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Recruiting | Taiwan Interstitial Lung Disease Multi-center Investigation and Registry NCT06476470 | Taichung Veterans General Hospital | — |
| Recruiting | Interstitial Lung Disease Registry Study: Prospective and Retrospective Observational Study in Austria NCT06522334 | Ludwig Boltzmann Institute for Lung Health | — |
| Recruiting | Assessing Functional Capacity in Directly and Remotely Monitored Home-based Settings: A Protocol for a Multina NCT06447831 | Laval University | — |
| Recruiting | Feasibility of Semaglutide in Advanced Lung Disease NCT05746039 | University of Pennsylvania | Phase 1 / Phase 2 |
| Completed | Hyperoxia During Pulmonary Rehabilitation in Chronic Lung Disease - Does it Matter? NCT06174207 | Eastern Switzerland University of Applied Sciences | N/A |
| Recruiting | Defining the Molecular and Radiologic Phenotype of Progressive RA Interstitial Lung Disease NCT06397677 | University of Colorado, Denver | — |
| Recruiting | 129Xe MRI Cardiopulmonary NCT06038630 | Bastiaan Driehuys | Phase 2 |
| Completed | Role of Lung Ultrasound in Screening for Interstitial Lung Disease in Patients With Rheumatoid Arthritis NCT06531785 | Assiut University | — |
| Not Yet Recruiting | NIV Versus HFO for Acute Exacerbations of Interstitial Lung Diseases NCT06182956 | ADIR Association | N/A |
| Active Not Recruiting | An Open-Label ProSpective MultiCENTer Study to Evaluate Safety and Tolerability of Dry Powder Inhaled Treprost NCT06129240 | Liquidia Technologies, Inc. | — |
| Recruiting | CT Quantitative Assessment of Interstitial Lung Disease NCT05947422 | Assiut University | — |
| Unknown | Risk Factors and Prognostic Parameters of Interstitial Lung Disease in Children NCT06125288 | Assiut University | — |
| Unknown | Comparison of Upper and Lower Limb Maximal Exercise Capacities and Muscle Oxygenation in Patients With ILD NCT06141603 | Gazi University | — |
| Unknown | Self-efficacy and Well-being of Patients With Fibrotic Interstitial Lung Disease NCT06027333 | Berner Reha Zentrum AG | — |
| Recruiting | Pulmonary Hypertension SOLAR NCT04778046 | Bastiaan Driehuys | Phase 2 |
| Recruiting | Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETO NCT05943535 | United Therapeutics | Phase 3 |
| Recruiting | Study to Evaluate the Efficacy, Safety, and Tolerability of Efzofitimod in Patients With Systemic Sclerosis (S NCT05892614 | aTyr Pharma, Inc. | Phase 2 |
| Terminated | Integrating ePReBMs From Phoenix in Respiratory Diseases NCT05827302 | University of Alberta | N/A |
| Unknown | HR Chest CT Visual Scoring, Spirometry and Health Related Quality of Life in Evaluating Severity of ILD Patien NCT05999838 | Assiut University | — |
| Unknown | Anxiety Management in Breathlessness. NCT06066658 | University of Leicester | N/A |
| Unknown | Effects of Incentive Spirometry With and Without Aerobic Exercises in Interstitial Lung Disease NCT06133998 | Riphah International University | N/A |
| Completed | Interstitial Lung Disease is a Risk Factor for Cardiovascular Disease NCT06539962 | Assiut University | — |
| Recruiting | Integrating Palliative Care Education in Pulmonary Rehabilitation NCT06046547 | Aveiro University | N/A |
| Recruiting | Telehealth and Onsite Maintenance Exercise in Chronic Lung Disease NCT06304207 | MGH Institute of Health Professions | N/A |
| Unknown | Usability and Acceptability Study of the P-STEP Mobile Application NCT05830318 | University of Leicester | — |
| Unknown | Clinical Study of 18F-FAPI-RGD in Interstitial Lung Disease Associated With Connective Tissue Disease NCT06143540 | Sichuan Provincial People's Hospital | — |
| Recruiting | Pulmonary Hypertension Screening in Patients With Interstitial Lung Disease for Earlier Detection NCT05776225 | United Therapeutics | — |
| Recruiting | A Multicenter Prospective Study of Risk Factors in Progressive Pulmonary Fibrosis NCT05895409 | Qianfoshan Hospital | — |
| Completed | Safety, Tolerability, PK and PD Study of AD-214 Administered to Healthy Volunteers and Patients With Interstit NCT05914909 | AdAlta Limited | Phase 1 |
| Unknown | Integrating Molecular, Genomic, Morphology and Environmental Features to Improve Precision Diagnosis and Treat NCT05998512 | Institut d'Investigació Biomèdica de Bellvitge | — |
| Unknown | Effects of Upper Extremity Aerobic Exercise Training in Patients With Interstitial Lung Disease NCT05916404 | Gazi University | N/A |
| Unknown | Effect of Short-term Oxygen During CPET in ILD NCT04897048 | University of Zurich | N/A |
| Completed | Specialist Dietetic Intervention in Malnourished Patients with Fibrotic ILD: a Randomised Controlled Pilot Tri NCT06016959 | Royal Brompton & Harefield NHS Foundation Trust | N/A |
| Unknown | Thorax MRI for Evaluation of Lung Morphology, Ventilation and Perfusion NCT04719078 | University of Zurich | N/A |
| Enrolling By Invitation | PRospective Evaluation of Interstitial Lung DIsease Progression With Quantitative CT NCT05609201 | University of Exeter | — |
| Active Not Recruiting | An Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) for Pulmonary Hypertension Associated Wit NCT05649722 | Insmed Incorporated | Phase 2 / Phase 3 |
| Recruiting | Interstitial Lung Disease Trajectories in Patients With Systemic Sclerosis NCT05345795 | Central Hospital, Nancy, France | — |
| Unknown | Move With Air: Exercise Training Study NCT05646407 | McGill University | N/A |
| Unknown | Move With Air: Physiological Response Assessment NCT05659550 | McGill University | N/A |
| Recruiting | Ultrasound and Respiratory Physiological Signals in Lung Diseases NCT06068647 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | N/A |
| Completed | A Study of Treprostinil to Treat Interstitial Lung Disease Pulmonary Hypertension NCT05564637 | Mayo Clinic | Phase 2 |
| Active Not Recruiting | ILD: Health Outcomes in Remote Digital Monitoring Versus Usual Care NCT05662124 | Imperial College Healthcare NHS Trust | N/A |
| Completed | Clinical Study of Multiple Dose Genakumab for Injection in Chinese Healthy Adults NCT05894148 | Changchun GeneScience Pharmaceutical Co., Ltd. | Phase 1 |
| Unknown | Telemedical Assistance in Automatic Titration of Oxygen for Intensive Care Patients NCT06090149 | Pauls Stradins Clinical University Hospital | N/A |
| Recruiting | Practice of Oxygenation and Respiratory Support During Fiberoptic Bronchoscopy NCT05681962 | University Magna Graecia | — |
| Recruiting | Correlation Between PaO2/FiO2 and Lung Ultrasound Score in the Intensive Care Unit NCT05631756 | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | N/A |
| Completed | Hiatal Hernia and Pulmonary Involvement NCT05716022 | University of Virginia | — |
| Recruiting | Efficacy of Video-Based Interactive Game Therapy in Interstitial Lung Patients NCT06087692 | Istanbul University | N/A |
| Recruiting | Evaluation of HRCT Patterns in Systemic Sclerosis-associated Interstitial Lung Disease NCT05482607 | Central Hospital, Nancy, France | — |
| Terminated | Assessment of Continuous Positive Airway Pressure Therapy in OSA and ILD NCT03901534 | Columbia University | N/A |
| Unknown | Physiological Effects of HFNC During Exercise in Patients With Fibrosing Interstitial Lung Diseases NCT05372926 | ADIR Association | N/A |
| Completed | Multinational Study of Efficacy and Safety of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary Fibro NCT05255991 | United Therapeutics | Phase 3 |
| Recruiting | Collagen-targeted PET Imaging for Early Interstitial Lung Disease NCT05417776 | Massachusetts General Hospital | Phase 2 |
| Enrolling By Invitation | Goals of Care Conversations Study NCT05001009 | VA Office of Research and Development | N/A |
| Enrolling By Invitation | Extension Study of Inhaled Treprostinil in Subjects With Fibrotic Lung Disease NCT04905693 | United Therapeutics | Phase 3 |
| Unknown | May Noninvasive Mechanical Ventilation (NIV) and/or Continuous Positive Airway Pressure (CPAP) Increase the Br NCT05631132 | Medical University of Silesia | N/A |
| Unknown | Tofacitinib in the Treatment of Rheumatoid Arthritis-related Interstitial Lung Disease. NCT05246293 | National Institute of Respiratory Diseases, Mexico | Phase 2 |
| Recruiting | Pulmonary Fibrosis Foundation Community Registry NCT05382572 | Pulmonary Fibrosis Foundation | — |
| Unknown | Pulmonary Care and Research Collaborative Patient Registry NCT05445817 | Pulmonary Care and Research Collaborative Limited | — |
| Unknown | Patient-Reported Outcome Study of Project ECHO for ILD NCT05450276 | Pulmonary Care and Research Collaborative Limited | — |
| Unknown | Efficacy and Safety of Pirfenidone in CTD-ILD NCT05505409 | Qilu Hospital of Shandong University | Phase 4 |
| Active Not Recruiting | Phase 2 Safety and Efficacy Study of Tulisokibart (MK-7240/PRA023) in Subjects With Systemic Sclerosis Associa NCT05270668 | Prometheus Biosciences, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) | Phase 2 |
| Completed | Palliative Care Planner (PCplanner) NCT05095363 | Duke University | N/A |
| Recruiting | Screening of Patients With Rheumatoid Arthritis for Interstitial Lung Disease NCT05391100 | Polyclinic of the Hospitaller Brothers of St. John of God, Budapest | — |
| Withdrawn | Efficacy and Safety of JAK Inhibitors in Systemic Sclerosis-associated Interstitial Lung Disease NCT05177471 | Central Hospital, Nancy, France | — |
| Unknown | Efficacy and Safety of Triple Therapy in Patients With Anti-MDA5 Antibody-positive Dermatomyositis NCT05375435 | The First Affiliated Hospital with Nanjing Medical University | Phase 4 |
| Unknown | A Cohort of Patients With Phenotyped Diffuse Interstitial Lung Disease With Longitudinal Follow-up NCT05810493 | Centre Hospitalier Universitaire de Nice | — |
| Terminated | Study of Trans Sodium Crocetinate in Patients With Interstitial Lung Disease NCT05079126 | Diffusion Pharmaceuticals Inc | Phase 2 |
| Completed | Rituxmab Versus IL-6 in Treating ILD NCT05963048 | Assiut University | Phase 2 / Phase 3 |
| Recruiting | FAPI PET for Lung Fibrosis NCT05365802 | University of California, Los Angeles | EARLY_Phase 1 |
| Recruiting | Efficacy of Two Doses of Duloxetine & Amitriptyline in Interstitial Lung Disease-related Cough NCT05120934 | Mayo Clinic | Phase 2 |
| Enrolling By Invitation | Global Utilization And Registry Database for Improved preservAtion of doNor LUNGs NCT04930289 | Paragonix Technologies | — |
| Recruiting | Precision Diagnosis and Care for Families With Pulmonary Fibrosis in Ireland NCT06702228 | Royal College of Surgeons, Ireland | — |
| Unknown | Digital Outpatient Services NCT05068869 | Oslo University Hospital | N/A |
| Completed | Virtual Exercise Program in Interstitial Lung Disease (ILD) Patients NCT04946708 | University of Manitoba | N/A |
| Recruiting | ILD-SARDs Registry and Biorepository NCT05007340 | McGill University Health Centre/Research Institute of the McGill University Health Centre | — |
| Unknown | The UK Interstitial Lung Disease Long-COVID19 Study (UKILD-Long COVID): Understanding the Burden of Interstiti NCT05514522 | Imperial College London | — |
| Recruiting | Interstitial Lung Disease Research Unit Biobank NCT05392881 | University of Kansas Medical Center | — |
| Completed | Remote Monitoring of Interstitial Lung Disease NCT04850521 | patientMpower Ltd. | — |
| Unknown | Remote Assessment of Lung Disease and Impact on Physical and Mental Health NCT05630599 | University College, London | — |
| Recruiting | Abatacept for the Treatment of Common Variable Immunodeficiency With Interstitial Lung Disease NCT04925375 | Children's Hospital Medical Center, Cincinnati | Phase 2 |
| Recruiting | Bio-Banking of Specimens for Advanced Lung Disease and Lung Transplant Research NCT04664192 | Baylor Research Institute | — |
| Completed | Cardiorespiratory Diagnostic Study NCT04939558 | TidalSense | — |
| Completed | Study of Efficacy and Safety of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary Fibrosis NCT04708782 | United Therapeutics | Phase 3 |
| Terminated | Tolerability and Safety of Nintedanib in Myositis Associated Interstitial Lung Disease NCT05335278 | McGill University Health Centre/Research Institute of the McGill University Health Centre | N/A |
| Completed | Systemic Corticosteroids in Treatment of Post-COVID-19 Interstitial Lung Disease NCT04988282 | Turkish Thoracic Society | Phase 4 |
| Terminated | A Study to Evaluate the Safety and Tolerability of Oral Ixazomib in Scleroderma-related Lung Disease Patients NCT04837131 | Michael M. Pham | Phase 2 |
| Completed | CENTR(AR): Lungs Moving NCT04711057 | Aveiro University | N/A |
| Completed | Correlation Between Lung UltraSound Score and Hypoxemia for Interstitial Syndrome in Emergency Department NCT04813900 | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | N/A |
| Suspended | Sjogren's Lung Study NCT04843345 | Stanford University | — |
| Unknown | The MONACO Cell Therapy Study: Monocytes as an Anti-fibrotic Treatment After COVID-19 NCT04805086 | Guy's and St Thomas' NHS Foundation Trust | Phase 1 / Phase 2 |
| Unknown | Rheumatoid Arthritis-Associated Interstitial Lung Disease: Characterization of Lung Disease Progression NCT04136223 | Hospital do Coracao | — |
| Unknown | Cyclophosphamide and Azathioprine vs Tacrolimus in Antisynthetase Syndrome-related Interstitial Lung Disease NCT03770663 | Assistance Publique - Hôpitaux de Paris | Phase 3 |
| Completed | ILAs in CT Lung Cancer Screening Population NCT04503044 | Lahey Clinic | — |
| Recruiting | Comparison of Imaging Quality Between Spectral Photon Counting Computed Tomography (SPCCT) and Dual Energy Com NCT04328181 | Hospices Civils de Lyon | N/A |
| Completed | SELF-BREATHE RCT for Chronic Breathlessness NCT04574050 | King's College Hospital NHS Trust | N/A |
| Recruiting | Magnetic Resonance Imaging of the Lung: Non-Oncological Applications NCT07493187 | Fondazione IRCCS Policlinico San Matteo di Pavia | — |
| Unknown | Clinical Study of MMF in Treatment of IIM-ILD and Its Effect on Peripheral Blood Treg Cells NCT05129410 | First Affiliated Hospital Xi'an Jiaotong University | Phase 4 |
| Completed | The Study of the Use of Nintedanib in Slowing Lung Disease in Patients With Fibrotic or Non-Fibrotic Interstit NCT04619680 | Icahn School of Medicine at Mount Sinai | Phase 4 |
| Unknown | Clinical Impact of HOME Oxygen SATURation Measurement (SATURHOME) NCT04624191 | Laval University | N/A |
| Terminated | Developing Optimal Parameters for Hyperpolarized Noble Gas and Inert Fluorinated Gas MRI of Lung Disorders NCT02748798 | Thunder Bay Regional Health Research Institute | EARLY_Phase 1 |
| Recruiting | Hyperpolarized 129Xe MR Imaging of Lung Function in Healthy Volunteers and Subjects With Pulmonary Disease NCT04624490 | Mario Castro, MD, MPH | Phase 1 |
| Completed | Lung Damage Caused by SARS-CoV-2 Pneumonia (COVID-19) NCT04435327 | University of Milano Bicocca | — |
| Active Not Recruiting | Genentech Validation Tool for Pulmonary Fibrosis NCT04676594 | Columbia University | — |
| Unknown | Clinical Study of Jianfei Kangfu Cao in the Treatment of pSS-ILD NCT04544722 | Shanghai University of Traditional Chinese Medicine | N/A |
| Completed | Inspiratory Muscle Training in Patients With Interstitial Lung Disease NCT04481074 | Federal University of Minas Gerais | N/A |
| Completed | Assessing Health Related Quality of Life in Hypersensitivity Pneumonitis NCT04273867 | Weill Medical College of Cornell University | — |
| Completed | Phase 1 Safety, Tolerability, PK & PD Study of AD-214 Administered to Healthy Volunteers NCT04415671 | AdAlta Limited | Phase 1 |
| Completed | Effects of Respiratory Muscle Functions on Interstitial Lung Disease: Sleep Quality, Dyspnea, and Fatigue NCT05993520 | Istanbul University | — |
| Unknown | Endobronchial Ultrasound Transbronchial Needle Aspiration Of Enlarged Mediastinal In Interstitial Lung Disease NCT04331548 | Sheba Medical Center | — |
| Completed | Identification Of Occupational Exposures In Patients With ILD NCT04879082 | Hospices Civils de Lyon | — |
| Unknown | Use of cSVF Via IV Deployment for Residual Lung Damage After Symptomatic COVID-19 Infection NCT04326036 | Black Tie Medical, Inc. | EARLY_Phase 1 |
| Unknown | Telemonitoring of Treatment Effects in Connective Tissue Disease-associated Interstitial Lung Disease (TEL-CTD NCT04428957 | Medical University of Lodz | N/A |
| Active Not Recruiting | Deciphering Rheumatoid Arthritis-associated Interstitial Lung Disease Pathogenesis 2 NCT04227535 | Assistance Publique - Hôpitaux de Paris | — |
| Completed | Inhaled Treprostinil in Sarcoidosis Patients With Pulmonary Hypertension NCT03814317 | University of Florida | Phase 2 |
| Completed | Multi-elemental Imaging of Lung Tissues With LIBS (Laser-induced Breakdown Spectroscopy) NCT03901196 | University Hospital, Grenoble | — |
| Completed | Effects of Exercise Training on Respiratory Performance in Patients With Fibrosing Interstitial Lung Diseases NCT05227443 | Alexandria University | N/A |
| Completed | Enhancing Physical Activity in Patients With Interstitial Lung Disease NCT04138173 | KU Leuven | N/A |
| Recruiting | Connective Tissue Diseases and Lung Manifestations NCT04095351 | Medical University Innsbruck | — |
| Unknown | Effect of Respiratory Muscle Training in Interstitial Lung Patients NCT05106556 | Bezmialem Vakif University | N/A |
| Completed | Effects of Inpatient Pulmonary Rehabilitation on Frailty in Patients After Lung-Transplantation NCT04184180 | Klaus Kenn | — |
| Unknown | Efficacy and Safety of Pirfenidone Treatment in HPS-ILD NCT04193592 | Jesse Roman | Phase 2 |
| Completed | Allogeneic Bone Marrow Mesenchymal Stem Cells for Patients With Interstitial Lung Disease (ILD) & Connective T NCT03929120 | Mayo Clinic | Phase 1 |
| Suspended | Coorticosteroid Regimen in Patients With Anti-PD-1/PD-L1 Induced Pneumonitis NCT04036721 | National Institute for Tuberculosis and Lung Diseases, Poland | Phase 4 |
| Unknown | Outcomes of RV Dysfunction in Acute Exacerbation of Chronic Respiratory Diseases NCT04098094 | Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil | — |
| Unknown | Long Term Oxygen Therapy in Patients With Interstitial Lung Disease NCT04089826 | Assiut University | — |
| Unknown | The Effect of Spontaneous Respiration on Pulse-oximetry Measurements NCT04139356 | Universidad Autonoma de Nuevo Leon | N/A |
| Unknown | Immunosuppressant Combined With Pirfenidone in CTD-ILD NCT04928586 | Qilu Hospital of Shandong University | Phase 4 |
| Unknown | Morphine to Maximize the Benefits of Exercise Training in COPD or ILD and Persistent Breathlessness NCT03824834 | Dennis Jensen, Ph.D. | Phase 2 |
| Unknown | The Comparison of Uniportal and Tubeless Video Assisted Thoracic Surgery and Transbronchial Lung Cryobiopsy in NCT03958162 | Guangzhou Institute of Respiratory Disease | N/A |
| Completed | Pilot Study: The Effects of Medical Music on Anxiety in Patients With ILD NCT04159584 | Weill Medical College of Cornell University | N/A |
| Unknown | Clinical Characteristics of Interstitial Pneumonia With Autoimmune Features (IPAF) - a Multicenter Prospective NCT03870828 | Medical University of Silesia | — |
| Terminated | Effects of Automated Oxygen Titration Alone or With High Flow Nasal Therapy on Dyspnea and Exercise Tolerance NCT05267418 | Laval University | N/A |
| Unknown | Diagnostic Value of Transbronchial Lung Cryobiopsy NCT02579304 | KU Leuven | — |
| Unknown | It's Not JUST Idiopathic Pulmonary Fibrosis Study NCT03670576 | University of Nottingham | — |
| Completed | Assessment of Exhaled Breath Condensate Hydrogen Peroxide (EBC H2O2) as Measured Using a New Device (Inflammac NCT04061356 | Portsmouth Hospitals NHS Trust | — |
| Active Not Recruiting | Assessment of Precision Irradiation in Early NSCLC and Interstitial Lung Disease NCT03485378 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | N/A |
| Unknown | Study Comparing Two Different Methods of Cryobiopsy in the Interstitial Lung Diseases NCT03727568 | University Hospital, Essen | N/A |
| Withdrawn | CompRehensive Phenotypic Characterization of Patients With Scleroderma-Associated ILD and PH NCT03726398 | Franz Rischard, DO | Phase 2 / Phase 3 |
| Enrolling By Invitation | University of Virginia Natural History Study NCT04896138 | University of Virginia | — |
| Completed | Reducing Disparities in the Quality of Advance Care Planning for Older Adults NCT03516994 | Duke University | N/A |
| Recruiting | Creation of a Biospecimen Repository From Patients With Interstitial Lung Diseases (ILD) NCT03478826 | Mayo Clinic | — |
| Recruiting | Autologous Stem Cell Transplantation in Patients With Systemic Sclerosis NCT03630211 | Paul Szabolcs | Phase 2 |
| Unknown | Novel Markers of Disease Progression in Interstitial Lung Disease NCT05760508 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Completed | Cost-effectiveness Analysis of Three Corticosteroids in ILDs NCT04982809 | Cairo University | N/A |
| Unknown | Assessment of Skeletal Muscle Dysfunction in Patient With Idiopathic Pulmonary Fibrosis NCT03440489 | Assiut University | N/A |
| Unknown | APRIL (AbatacePt in Rheumatoid Arthritis-ILD) NCT03084419 | Cambridge University Hospitals NHS Foundation Trust | Phase 2 |
| Completed | Toward Self-management in ILD NCT03300583 | Kingston University | — |
| Unknown | Interstitial Lung Disease in Early Rheumatoid Arthritis NCT03977415 | National Jewish Health | — |
| Completed | Families-At-risk for Interstitial Lung Disease Study NCT03641742 | Columbia University | — |
| Completed | Abatacept for the Treatment of Myositis-associated Interstitial Lung Disease NCT03215927 | Rohit Aggarwal, MD | Phase 2 |
| Completed | A Study to Characterize the Disease Behavior of Idiopathic Pulmonary Fibrosis (IPF) and Interstitial Lung Dise NCT03261037 | Hoffmann-La Roche | N/A |
| Completed | Scleroderma Lung Study III - Combining Pirfenidone With Mycophenolate NCT03221257 | Michael Roth | Phase 2 |
| Completed | Interstitial Lung Disease Within a Lung Cancer Screening NCT04715347 | Manchester University NHS Foundation Trust | — |
| Completed | The Role of Physical Activity and Diet Within Pulmonary Sarcoidosis NCT03336736 | Kingston University | — |
| Unknown | Best Clinical Endpoints That Likely Induce Worse Prognosis in Interstitial Lung Diseases NCT03400839 | Universidade Estadual de Londrina | — |
| Completed | The Effects of Breathing Retraining in Patients With Interstitial Lung Diseases NCT03729583 | University of Malta | N/A |
| Completed | Assessment of Lung Movement With Computed Tomography (CT) NCT03068091 | University of Missouri-Columbia | N/A |
| Completed | CASPA: CArdiac Sarcoidosis in PApworth NCT03599414 | Papworth Hospital NHS Foundation Trust | — |
| Recruiting | Rheumatoid Arthritis Patients at Risk for Interstitial Lung Disease NCT03297775 | University of Colorado, Denver | — |
| Terminated | Study of Efficacy and Safety of Pirfenidone in Patients With Fibrotic Hypersensitivity Pneumonitis NCT02958917 | Evans Fernandez Perez | Phase 2 |
| Completed | An In Silico Trial to Evaluate Prospectively the Performance of a Radiomics Algorithm for UIP Compared to Medi NCT05784207 | Maastricht University | — |
| Completed | Lung Tissue Research Consortium NCT02988388 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Safety and Efficacy of Inhaled Treprostinil in Adult PH With ILD Including CPFE NCT02630316 | United Therapeutics | Phase 2 / Phase 3 |
| Completed | The FVC/DLCO Ratio is a Useful Predictor of Pulmonary Hypertension in Patients With Interstitial Lung Disease NCT03396120 | Assiut University | — |
| Completed | Investigation of Pectoralis Muscle Strength in Elderly With Interstitial Lung Disease NCT04803617 | Habibedurdu | — |
| Completed | Opportunistic Screening for Osteoporotic Vertebral Fractures in Patients With Diffuse Interstitial Lung Diseas NCT05714787 | Centre Hospitalier Universitaire de Nice | — |
| Completed | An Observational Outcomes Study for Autologous Cell Therapy Among Patients With COPD and Interstitial Lung Dis NCT03040674 | Lung Institute | — |
| Completed | Nebulized Fentanyl in Patients With Mild to Moderate Interstitial Lung Disease and Chronic Dyspnea NCT03018756 | Dr. Denis O'Donnell | Phase 3 |
| Completed | Value of Chest Ultrasonography in ILD Screening NCT06260930 | Aswan University | — |
| Unknown | Effects of Whole Body Vibration Training in Patients With Interstitial Lung Disease NCT03560154 | Istanbul University | N/A |
| Completed | Predictors for Bronchoalveolar Lavage (BAL) Recovery Rate Derived From Quantified Computed Tomography (qCT) NCT03388580 | Universitätsmedizin Mannheim | — |
| Completed | Pursed Lip Breathing in Interstitial Lung Disease NCT02934750 | Centre hospitalier de l'Université de Montréal (CHUM) | N/A |
| Completed | Study to Compare the Efficacy of Mycophenolate Mofetil in Systemic Sclerosis Related Early Interstitial Lung D NCT02896205 | Post Graduate Institute of Medical Education and Research, Chandigarh | Phase 3 |
| Unknown | Treatment Outcome and Prognostic Factors for Rheumatoid Arthritis (RA) Patients With Interstitial Lung Disease NCT03099525 | Hanyang University | — |
| Terminated | An Open Label Extension Study to Evaluate Inhaled Treprostinil in Adult PH With ILD Including CPFE NCT02633293 | United Therapeutics | Phase 2 / Phase 3 |
| Unknown | Multicenter Study of Impulse Oscillometry in Chinese NCT03467880 | Guangzhou Institute of Respiratory Disease | — |
| Terminated | Safety of Anti-Depressant for Chronic Obstructive Pulmonary Disease (SAD-COPD) NCT02813447 | Duke University | N/A |
| Unknown | The Coagulation Cascade in Idiopathic Pulmonary Fibrosis NCT02885961 | University College, London | N/A |
| Unknown | Pirfenidone in Progressive Interstitial Lung Disease Associated With Clinically Amyopathic Dermatomyositis NCT02821689 | RenJi Hospital | Phase 4 |
| Unknown | Interstitial Lung Diseases in the Veterans Administration NCT02479126 | Robert Tighe | — |
| Completed | Autologous Stem Cell Treatment for Chronic Lung Disease Study NCT03044431 | Lung Institute | — |
| Unknown | The Effects of Glucocorticoids on Glucose Metabolism in Patients With Interstitial Lung Disease NCT02824757 | Peking Union Medical College Hospital | — |
| Completed | Safety & Suitability of Dabigatran to Inhibit Thrombin in Scleroderma NCT02426229 | Medical University of South Carolina | Phase 1 |
| Unknown | Evaluation of Novel Lung Function Parameters and Quantitative Computed Tomography (qCT) in Patients With Pulmo NCT02826265 | Universitätsmedizin Mannheim | — |
| Completed | Palliation of Dyspnea With Morphine in Patients With Interstitial Lung Disease NCT02622022 | University of Aarhus | Phase 4 |
| Completed | Integration of Cryobiopsies for ILD Diagnoses- Experience Based on 250 Biopsy Procedures. NCT05311345 | Aarhus University Hospital | — |
| Unknown | Evaluation of Novel Lung Function Parameters in Patients With Interstitial Lung Disease (ILD) NCT02827734 | Universitätsmedizin Mannheim | — |
| Terminated | Hydroxychloroquine (HCQ) in Pediatric Interstitial Lung Disease (ILD) NCT02615938 | Matthias Griese | Phase 2 |
| Completed | Neuromuscular Electrical Stimulation in Patients With Interstitial Lung Disease NCT02497144 | Gazi University | N/A |
| Completed | The NIH Exercise Therapy for Advanced Lung Disease Trials: Response and Adaptation to Aerobic Exercise in Pati NCT02019641 | National Institutes of Health Clinical Center (CC) | N/A |
| Completed | Evaluation of a Multi-professional Breathlessness Service for Patients With Breathlessness Due to Any Advanced NCT02622412 | Ludwig-Maximilians - University of Munich | N/A |
| Completed | Rituximab Versus Cyclophosphamide in Connective Tissue Disease-ILD NCT01862926 | Royal Brompton & Harefield NHS Foundation Trust | Phase 2 / Phase 3 |
| Unknown | Open Label Trial of Utility of Cryobiopsy in the Multidisciplinary Diagnosis of Idiopathic Interstitial Lung D NCT02563730 | University Hospital Tuebingen | N/A |
| Unknown | Diagnostic Yield of Transbronchial Cryobiopsy in Diagnosis of Interstitial Lung Diseases NCT02235779 | Laval University | N/A |
| Unknown | Evaluation of a Lightweight Nasal Interface and Ventilator in Patients With Respiratory Disease NCT02278107 | New Aera, Inc | N/A |
| Completed | Stylet vs No Stylet During EBUS TBNA NCT02201654 | Johns Hopkins University | N/A |
| Completed | Bardoxolone Methyl Evaluation in Patients With Pulmonary Hypertension (PH) - LARIAT NCT02036970 | Biogen | Phase 2 |
| Unknown | Patients With Pulmonary Hypertension or Interstitial Lung Disease at Altitude - Effect of Oxygen on Breathing NCT02150616 | University of Zurich | Phase 4 |
| Completed | A Trial on Clinical Efficacy of 1% Versus 2% Lignocaine in Cough Suppression and Pain Relief in Patients Under NCT01955824 | Post Graduate Institute of Medical Education and Research, Chandigarh | Phase 2 / Phase 3 |
| Completed | Patients With Pulmonary Hypertension or Interstitial Lung Disease at Altitude - Effect of Oxygen on Exercise P NCT02143687 | University of Zurich | Phase 4 |
| Completed | Anti-neutrophil Cytoplasmic Antibody in Interstitial Lung Disease. NCT04413149 | Peking Union Medical College Hospital | — |
| Unknown | The Role of Gastroesophageal Reflux in Scleroderma Pulmonary Fibrosis NCT02136394 | Royal Brompton & Harefield NHS Foundation Trust | — |
| Unknown | Interstitial Lung Disease Registry Construction NCT03238989 | Seoul National University Hospital | — |
| Completed | Duration of Exercise Program in Interstitial Lung Diseases. NCT03302702 | Izmir Katip Celebi University | N/A |
| Completed | The Role of KL-6 in the Clinical Diagnosis of ILD NCT02197364 | Shanghai Pulmonary Hospital, Shanghai, China | — |
| Completed | Cardiopulmonary Exercise Testing in Interstitial Lung Disease NCT02636452 | Wissenschaftliches Institut Bethanien e.V | — |
| Completed | Ambulatory Oxygen for ILD NCT01906931 | Anne Holland | Phase 2 |
| Completed | Comparison of Transbronchial, Cryoprobe, and VATS Biopsy for the Diagnosis of Interstitial Lung Disease NCT02075762 | Johns Hopkins University | N/A |
| Completed | Prospective Validation of Cough, Dyspnea, and Quality of Life Questionnaires in Patients With IPF NCT01874223 | Stanford University | — |
| Completed | Comparison of Transbronchial, Cryoprobe and VATS Biopsy For the Diagnosis of Interstitial Lung Disease (ILD) NCT01972685 | Duke University | N/A |
| Unknown | The Role of Rheumatological Evaluation in the Management of Patients With Interstitial Lung Disease NCT01809574 | Meir Medical Center | — |
| Completed | MIF- Thyroxine Interactions in the Pathogenesis of Pulmonary Arterial Hypertension NCT02858791 | Northwell Health | — |
| Completed | Safety and Efficacy of Allogeneic Mesenchymal Stem Cells in Patients With Rapidly Progressive Interstitial Lun NCT02594839 | Federal Research Clinical Center of Federal Medical & Biological Agency, Russia | Phase 1 / Phase 2 |
| Completed | Cyclophosphamide Systemic Sclerosis Associated Interstitial Lung Disease NCT01570764 | Assistance Publique - Hôpitaux de Paris | Phase 3 |
| Unknown | Interstitial Lung Disease Questionnaire NCT01711151 | University of East Anglia | — |
| Completed | Cryobiopsy vs. VATS in Diagnosis of Interstitial Lung Diseases NCT01714518 | Wissenschaftliches Institut Bethanien e.V | — |
| Recruiting | WTC Chest CT Imaging Archive NCT03295279 | Icahn School of Medicine at Mount Sinai | — |
| Terminated | Study of Pomalidomide (CC-4047) to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Effec NCT01559129 | Celgene | Phase 2 |
| Completed | Specific Autoantibody Testing in Patients With Interstitial Lung Disease NCT01600352 | Singapore General Hospital | — |
| Completed | Effects of an Oxymizer on Endurance Time in Patients With Chronic Lung Diseases NCT01713413 | Schön Klinik Berchtesgadener Land | N/A |
| Completed | Interstitial Lung Disease Associated NCT06007040 | Peking Union Medical College Hospital | — |
| Completed | Prospective, Randomised Multicenter Study Comparing the Efficacy of Transbronchial Forceps Biopsy With Cryobio NCT01894113 | University Hospital Tuebingen | N/A |
| Terminated | A Clinical Trial for CTD-ILD Treatment NCT01424033 | University of Michigan | Phase 2 / Phase 3 |
| Completed | Double-blind Placebo-controlled Pilot Study of Sirolimus in Idiopathic Pulmonary Fibrosis (IPF) NCT01462006 | University of Virginia | N/A |
| Completed | "Diagnostic Yield and Safety of Transbronchial Lung Biopsy Using Cryoprobes Versus Conventional Forceps. NCT01064609 | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | N/A |
| Terminated | A Study to Characterize the Safety, PK and Biological Activity of CC-930 in Idiopathic Pulmonary Fibrosis (IPF NCT01203943 | Celgene | Phase 2 |
| Completed | Mechanical Ventilation in Interstitial Lung Disease NCT03416075 | Beijing Chao Yang Hospital | — |
| Recruiting | Hyperpolarized 129Xe MRI for Imaging Pulmonary Function NCT01280994 | Bastiaan Driehuys | Phase 2 |
| Completed | The Natural History of Small Airways Physiology in Diseased and Healthy States NCT00677560 | Imperial College London | — |
| Completed | The Six Minute Walk Test: Influence of Instruction on Results NCT01789996 | Inova Health Care Services | N/A |
| Completed | The Impact of Pulmonary Rehabilitation in Interstitial Lung Disease NCT01055730 | University of California, San Francisco | — |
| Completed | Comparison of Therapeutic Regimens for Scleroderma Interstitial Lung Disease (The Scleroderma Lung Study II) NCT00883129 | Michael Roth | Phase 2 |
| Completed | Biomarkers in the Evaluation of Chronic Lung Disease NCT00926523 | Northwell Health | — |
| Completed | Pulmonary Rehabilitation in Interstitial Lung Diseases NCT00882817 | KU Leuven | Phase 4 |
| Completed | Biomarkers in Pulmonary Hypertension Associated to Interstitial Lung Disease NCT00820729 | University of Aarhus | — |
| Completed | Treprostinil Therapy For Patients With Interstitial Lung Disease And Severe Pulmonary Arterial Hypertension NCT00705133 | Rajan Saggar | Phase 2 |
| Completed | Aerobic Exercise in Patients With Pulmonary Hypertension NCT00678821 | National Institutes of Health Clinical Center (CC) | Phase 2 |
| Unknown | Bosentan in Pulmonary Hypertension in Interstitial Lung Disease Treatment Study NCT00637065 | Royal Brompton & Harefield NHS Foundation Trust | Phase 4 |
| Unknown | Segmentation of Structural Abnormalities in Chronic Lung Diseases NCT04760548 | Hôpital Haut Lévêque | — |
| Terminated | Use Of Capnography As Surrogate Measure Of PC02 In Medical Intensive Care Unit (ICU) Patients NCT00744614 | Lahey Clinic | — |
| Enrolling By Invitation | The Edinburgh Lung Fibrosis Molecular Endotyping (ELFMEN) Study NCT04016181 | University of Edinburgh | — |
| Withdrawn | Pulmonary Hypertension Secondary to Idiopathic Pulmonary Fibrosis And Treatment With Sildenafil NCT00625079 | University of California, Los Angeles | Phase 4 |
| Completed | Race, Ethnicity, and Diffuse Parenchymal Lung Disease NCT00453713 | Columbia University | — |
| Completed | Blood Collection From Individuals With Lung Disease for Genetic Studies (Qatar) NCT00504361 | Weill Medical College of Cornell University | — |
| Completed | Blood Collection From Individuals With Lung Disease for Genetic Studies NCT00362739 | Weill Medical College of Cornell University | — |
| Unknown | Pulmonary Rehabilitation in Interstitial Lung Disease NCT00168285 | The Alfred | N/A |
| Completed | To Evaluate the Use of Radiomics to Classify Between Idiopathic Pulmonary Fibrosis and Interstitial Lung Disea NCT04430491 | Maastricht University | — |
| Completed | Open-label Study With Bosentan in Interstitial Lung Disease NCT00319033 | Actelion | Phase 2 / Phase 3 |
| Terminated | Evaluation of the Diagnostic Utility of INS316 in Patients With Interstitial Lung Diseases (01-701) NCT01381666 | Merck Sharp & Dohme LLC | Phase 2 |
| Available | Inhaled Treprostinil Expanded Access Program in Pulmonary Hypertension Associated With Interstitial Lung Disea NCT05572996 | Ferrer Internacional S.A. | — |