Clinical Trials Directory

Trials / Recruiting

RecruitingNCT07179380

Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)

A Phase 3, Randomized, Double-blind, Placebo-controlled, Multicenter, Parallel Group Study to Evaluate the Efficacy and Safety of Treprostinil Palmitil Inhalation Powder in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease

Status
Recruiting
Phase
Phase 3
Study type
Interventional
Enrollment
344 (estimated)
Sponsor
Insmed Incorporated · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The primary objective of this study is to evaluate the effect of 24-weeks of once daily treatment with TPIP versus placebo on exercise capacity in adults with PH-ILD.

Conditions

Interventions

TypeNameDescription
DRUGTreprostinil Palmitil Inhalation PowderOral inhalation using a capsule-based dry powder inhaler device.
DRUGPlaceboOral inhalation using a capsule-based dry powder inhaler device.

Timeline

Start date
2026-01-07
Primary completion
2028-12-30
Completion
2028-12-30
First posted
2025-09-17
Last updated
2026-04-14

Locations

68 sites across 21 countries: United States, Argentina, Australia, Belgium, Czechia, Denmark, France, Georgia, Germany, Greece, Israel, Italy, Japan, New Zealand, Portugal, Romania, South Korea, Spain, Switzerland, Taiwan, United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT07179380. Inclusion in this directory is not an endorsement.