| Not Yet Recruiting | A Study to Evaluate the Efficacy and Safety of Once Daily Treprostinil Palmitil Inhalation Powder (TPIP) in Pa Pulmonary Arterial Hypertension | Phase 3 | 2026-04-17 |
| Not Yet Recruiting | An Open-Label Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Pulmonary Hypertension, Interstitial Lung Disease | Phase 3 | 2026-04-01 |
| Recruiting | Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hyp Pulmonary Hypertension, Interstitial Lung Disease | Phase 3 | 2026-01-07 |
| Completed | A Study to Assess the Relative Bioavailability After a Single Inhalation Administration of Treprostinil Palmit Healthy Volunteers | Phase 1 | 2025-08-19 |
| Active Not Recruiting | A Study of the Efficacy and Safety of Brensocatib in Adults With Moderate to Severe Hidradenitis Suppurativa ( Hidradenitis Suppurativa | Phase 2 | 2024-12-16 |
| Completed | A Study to Assess the Relative Bioavailability of Brensocatib Pediatric Oral Solution to Oral Tablets in Healt Healthy Participants | Phase 1 | 2024-04-30 |
| Completed | A Study of the Palatability and Acceptability of Different Brensocatib Oral Liquid Formulations in Healthy Par Healthy Volunteers | Phase 1 | 2023-12-27 |
| Completed | A Study of the Efficacy and Safety of Brensocatib in Participants With Chronic Rhinosinusitis Without Nasal Po Chronic Rhinosinusitis Without Nasal Polyps | Phase 2 | 2023-10-30 |
| Completed | A Study to Investigate Effect of Clarithromycin, a Strong CYP3A4 Inhibitor, on Brensocatib Pharmacokinetics in Healthy Volunteers | Phase 1 | 2023-07-28 |
| Active Not Recruiting | An Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) for Pulmonary Hypertension Associated Wit Pulmonary Hypertension, Interstitial Lung Disease | Phase 2 / Phase 3 | 2023-05-11 |
| Completed | A Study to Assess Pharmacokinetics (PK) of Brensocatib Alone and With Multiple Doses of Rifampin or Esomeprozo Healthy Volunteers | Phase 1 | 2023-05-10 |
| Active Not Recruiting | An Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) for Pulmonary Arterial Hypertension (PAH) Pulmonary Arterial Hypertension | Phase 2 / Phase 3 | 2023-03-07 |
| Completed | A Study to Evaluate the Safety and Tolerability of Treprostinil Palmitil Inhalation Powder in Participants Wit Pulmonary Hypertension | Phase 2 | 2022-12-22 |
| Completed | A Study to Evaluate the Pharmacokinetics (PK) and Safety of a Single Dose of Brensocatib in Participants With Hepatic Impairment | Phase 1 | 2022-10-04 |
| Completed | A Study to Evaluate the Efficacy, Safety and Pharmacokinetics of Treprostinil Palmitil Inhalation Powder in Pa Pulmonary Arterial Hypertension | Phase 2 | 2022-08-24 |
| Completed | A Study to Investigate the Effects of Brensocatib on QT Interval in Healthy Participants Healthy Volunteer | Phase 1 | 2022-04-27 |
| Terminated | A Study of Treprostinil Palmitil Inhalation Powder (TPIP) In Pulmonary Arterial Hypertension (PAH) Pulmonary Arterial Hypertension | Phase 2 | 2022-03-29 |
| Completed | A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Brensocatib Tablets in Adults With Cystic Cystic Fibrosis | Phase 2 | 2021-11-30 |
| Completed | A Study of the Absorption, Metabolism, and Excretion of [14C]-Brensocatib Following a Single Oral Administrati Healthy Volunteers | Phase 1 | 2021-08-13 |
| Completed | A Study of Brensocatib Following a Single Oral Administration in Participants With or Without Renal Impairment Renal Impairment | Phase 1 | 2021-07-20 |
| Completed | Study to Evaluate ALIS (Amikacin Liposome Inhalation Suspension) in Participants With Nontuberculous Mycobacte Mycobacterium Infections, Nontuberculous | Phase 3 | 2021-04-01 |
| Completed | Validation of Patient Reported Outcome Measures in Participants With Nontuberculous Mycobacterial Lung Infecti Mycobacterium Infections, Nontuberculous | Phase 3 | 2020-12-22 |
| Completed | A Study to Assess the Efficacy, Safety, and Tolerability of Brensocatib in Participants With Non-Cystic Fibros Non-Cystic Fibrosis Bronchiectasis | Phase 3 | 2020-12-01 |
| Completed | A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Treprostinil Palmitil Inhalation Powder ( Healthy Volunteers | Phase 1 | 2020-09-17 |
| Completed | A Study of the Safety, Pharmacokinetics, and Pharmacodynamics of INS1007 in Healthy Japanese and Caucasian Par Healthy Volunteers | Phase 1 | 2019-01-09 |
| Completed | Assessment of INS1007 in Participants With Non-Cystic Fibrosis Bronchiectasis Non-Cystic Fibrosis Bronchiectasis | Phase 2 | 2017-10-31 |
| Completed | Open-label Safety Extension Study Assessing Safety and Tolerability of LAI in Patients Who Participated in Stu NTM Lung Infection Due to MAC | Phase 3 | 2016-02-05 |
| Completed | A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of C16TR for Inhalation With Tyvaso® Cohort Healthy Volunteers | Phase 1 | 2015-11-17 |
| Completed | Study to Evaluate Efficacy of LAI When Added to Multi-drug Regimen Compared to Multi-drug Regimen Alone Mycobacterium Infections, Nontuberculous | Phase 3 | 2015-05-27 |
| Completed | Extension Study of Liposomal Amikacin for Inhalation in Cystic Fibrosis (CF) Patients With Chronic Pseudomonas Cystic Fibrosis | Phase 3 | 2012-10-05 |
| Completed | Liposomal Amikacin for Inhalation (LAI) for Nontuberculous Mycobacteria Mycobacterium Infections, Nontuberculous | Phase 2 | 2012-04-19 |
| Completed | Study to Evaluate Arikayce™ in CF Patients With Chronic Pseudomonas Aeruginosa Infections Pseudomonas Aeruginosa Infection | Phase 3 | 2012-02-29 |
| Completed | Study of Dose Escalation of Liposomal Amikacin for Inhalation (ARIKAYCE™) - Extension Phase Cystic Fibrosis | Phase 2 | 2009-01-08 |
| Completed | Safety and Tolerability Study of 2 Dose Level of Arikayce™ in Patients With Bronchiectasis and Chronic Infecti Bronchiectasis | Phase 2 | 2008-06-24 |
| Completed | Safety/Tolerability Study of Arikayce™ in Cystic Fibrosis Patients With Chronic Infection Due to Pseudomonas A Cystic Fibrosis | Phase 1 / Phase 2 | 2008-01-01 |
| Completed | Safety and Efficacy Study of Recombinant Human Insulin-Like Growth Factor-I/Recombinant Human Insulin-Like Gro Myotonic Dystrophy Type 1 | Phase 2 | 2007-12-01 |
| Completed | Multidose Safety and Tolerability Study of Dose Escalation of Liposomal Amikacin for Inhalation (ARIKACE™) Cystic Fibrosis | Phase 1 / Phase 2 | 2007-02-22 |
| Completed | Inhalation SLIT Cisplatin (Liposomal) for the Treatment of Osteosarcoma Metastatic to the Lung Osteosarcoma Metastatic | Phase 1 / Phase 2 | 2005-01-12 |
| Completed | A Study to Investigate Lung Deposition of Inhaled Amikacin-loaded Liposomes in Healthy Male Participants Healthy Volunteers | Phase 1 | 2004-06-02 |
| Completed | Single Dose Escalation Study of TR02 (Sustained Lipid Inhalation Technology [SLIT™] Amikacin) in Participants Cystic Fibrosis | Phase 1 | 2004-05-12 |
| Withdrawn | Study to Evaluate Arikace™ in CF Patients With Chronic Infection Due to Pseudomonas Aeruginosa Cystic Fibrosis | Phase 3 | — |
| Available | An Expanded Access Study to Assess Treprostinil Palmitil Inhalation Powder (TPIP) for Participants With Pulmon Pulmonary Arterial Hypertension, Pulmonary Hypertension, Interstitial Lung Disease | — | — |
| Approved For Marketing | An Expanded Access Study to Assess Brensocatib for Participants With Non-Cystic Fibrosis Bronchiectasis Non-Cystic Fibrosis Bronchiectasis | — | — |
| Terminated | Research Study Using Recombinant Human Insulin-Like Growth Factor-1/Recombinant Human Insulin-Like Growth Fact Noonan Syndrome | Phase 2 | — |
| Completed | IGF-I/IGFBP-3 Therapy in Children and Adolescents With Growth Hormone Insenitivity Syndrome (GHIS) Such as Lar Growth Hormone Insensitivity Syndrome (GHIS), Laron Syndrome | Phase 2 / Phase 3 | — |