NCT05482607

Evaluation of HRCT Patterns in Systemic Sclerosis-associated Interstitial Lung Disease

Unsupervised Clustering Evaluation of HRCT Patterns in Systemic Sclerosis-associated Interstitial Lung Disease

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: Central Hospital, Nancy, France · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Systemic sclerosis (SSc) is a heterogeneous systemic autoimmune disease with distinct prognosis according to patients. Interstitial lung disease (ILD) concerns almost 50 % of SSc patients and represents the main cause of mortality. SSc-ILD is variable: from limited forms (with asymptomatic patients) to extensive lesions. Disease course in SSc-ILD is also highly variable: patients can experience stable disease, slow or fast progression. Investigators performed unsupervised clustering analysis to classify SSc-ILD according to elementary radiological lesions on HRCT scan.

Conditions

• Systemic Sclerosis
• Interstitial Lung Disease

Timeline

• Start date: 2023-01-01
• Primary completion: 2025-10-01
• Completion: 2025-10-01
• First posted: 2022-08-01
• Last updated: 2024-08-27

Locations

1 site across 1 country: France