| Not Yet Recruiting | The Practicality and Utility of Measured vs Estimated GFR in adCKD Chronic Kidney Disease (Stages 4 and 5), Chronic Kidney Disease 5D | — | 2026-02-01 |
| Enrolling By Invitation | DENTOFACIAL-PBT Stage 2 - Feasibility Study Head and Neck Cancer, Radiotherapy Side Effect, Adverse Effect of Radiation Therapy | — | 2026-01-16 |
| Not Yet Recruiting | Barriers and Enablers to Accessing Medical Care for Urinary Incontinence and Prolapse in GLobal Majority Women Pelvic Prolapse Conditions | — | 2025-12-01 |
| Not Yet Recruiting | Glucose Levels in Acute Pancreatitis and the Impact of Insulin Depletion and Bacterial Endotoxaemia Pancreatitis, Acute, Hyperglycaemia | — | 2025-12-01 |
| Not Yet Recruiting | The AcCREDiT 2 Study Chronic Respiratory Conditions, COPD, Pneumonia | — | 2025-07-01 |
| Recruiting | Exploring the Lived Experience of Young Adults With Severe Asthma Asthma, Severe Asthma, Uncontrolled Asthma | — | 2024-11-25 |
| Withdrawn | Arterial Blood Pressure and Cardiac Arrest Cardiac Arrest | — | 2024-09-01 |
| Active Not Recruiting | Disparities In Access to the Northwest Ambulance Service During Pregnancy, Birth and Postpartum Period and Its Emergency Maternity Care, Health Inequalities in Maternity Care Access, Disparities in Access to Maternity Care | — | 2024-09-01 |
| Active Not Recruiting | Spasmodic Dysphonia Interviews Spasmodic Dysphonia, Quality of Life | — | 2024-08-20 |
| Recruiting | Interferon-gamma as Adjunctive Therapy in Chronic Pulmonary Aspergillosis: a Randomised Feasibility Study Chronic Pulmonary Aspergillosis, Aspergillosis | Phase 2 | 2024-05-17 |
| Recruiting | Real-world Elecsys® GAAD Implementation and Validation to Improve Surveillance and Early Detection of HCC Liver Cirrhosis, Hepatocellular Carcinoma | N/A | 2024-01-08 |
| Completed | Therapeutic Drug Monitoring - Targeting IMproved Effectiveness Pneumonia, Sepsis, Infection, Bacterial | — | 2023-12-12 |
| Not Yet Recruiting | Quantifying Artificial Pancreas-related Changes in Diabetic Neuropathy Diabetes Complications, Diabetes Mellitus, Type 1, Diabetic Neuropathies | N/A | 2023-12-01 |
| Completed | Strong Albumin Solutions in Patients With Septic Shock Sepsis, Septic Shock, Shock, Toxic | Phase 2 / Phase 3 | 2023-11-10 |
| Recruiting | Detecting EARLY Heart Failure in Greater Manchester Heart Failure | — | 2023-10-09 |
| Unknown | Evaluation of Patients' Requirements for Improved Advice and Guidance on Vision Standards for Driving in Glauc Glaucoma | — | 2023-08-25 |
| Unknown | Automated Fully Closed-Loop Insulin Delivery in Type 1 Diabetes With Ultra-Rapid Lispro (ACOLYTE Study) Diabetes Mellitus, Type 1 | N/A | 2023-07-21 |
| Unknown | Validation and Reliability of Iris Cameras in Mucopolysaccharidoses Mucopolysaccharidoses | — | 2023-03-08 |
| Recruiting | Enhanced Rehabilitation After Major Trauma (PROPERLY) Major Trauma | N/A | 2023-02-24 |
| Unknown | Breast CANcer Risk Assessment in Younger Women: BCAN-RAY Breast Cancer Female | — | 2023-01-31 |
| Unknown | Remote Glucose Monitoring in Hospital Settings Diabetes Mellitus, Type 2, Hyperglycemia Stress, Hypoglycemia | N/A | 2023-01-09 |
| Withdrawn | Oxygen-enhanced Magnetic Resonance Imaging (OE-MRI) of the Heart: A Feasibility Study Coronary Artery Disease | — | 2023-01-01 |
| Unknown | Manchester Intermittent Diet in Gestational Diabetes Acceptability Study Gestational Diabetes, Gestational Diabetes Mellitus in Pregnancy, Intermittent Fasting | N/A | 2022-11-24 |
| Completed | Neuromuscular Stimulation Versus Intermittent Compression for Venous Thromboembolism Prophylaxis in Critical C Critical Illness, Sepsis, Acute Illness | N/A | 2022-11-01 |
| Recruiting | UK Heart Failure With Preserved Ejection Fraction Heart Failure With Preserved Ejection Fraction (HFpEF) | — | 2022-10-07 |
| Unknown | What Affects Willingness to Self-manage a Pessary? Prolapse; Female, Prolapse, Vaginal | — | 2022-08-25 |
| Recruiting | Characteristics, Phenotypes, and TRAITS of Heart Failure With Preserved Ejection Fraction (TRAITS-HFpEF) Heart Failure With Preserved Ejection Fraction (HFpEF) | — | 2022-08-12 |
| Completed | Safe and Effective Above Cuff Tracheostomy Ventilation Tracheostomy | N/A | 2022-07-13 |
| Unknown | Improving HbA1c Levels Through Behavioural Change of Diabetes Self-management Assisted by the LovedBy Mobile A Diabetes Mellitus, Type 1 | N/A | 2022-06-30 |
| Unknown | PeriviAble DeLiveries: ALIgning PArental aNd PhysiCian PrioritiEs (ALLIANCE) Periviable Infants, Extreme Prematurity, Communication | — | 2022-05-31 |
| Unknown | Questionnaire Study to Assess the Outcomes of the Management of Congenital Adrenal Hyperplasia Individuals Adrenal Hyperplasia, Congenital | — | 2022-02-28 |
| Unknown | Comparing the Side-lying Sleep Positioning to Back-lying in Infants With Cleft Palate Obstructive Sleep Apnea, Cleft Palate | N/A | 2022-01-28 |
| Unknown | Manchester Intermittent and Daily Diet Type 1 Diabetes App Study (MIDDAS-Type 1) Type 1 Diabetes, Obesity | N/A | 2022-01-19 |
| Completed | Personality Traits in Patients Seeking a Consultation for Treatment for Floaters Myodesopia | — | 2021-12-15 |
| Unknown | Enhanced Monitoring for Better Recovery and Cancer Experience in Greater Manchester Colorectal Cancer, Lung Cancer, Hematological Cancer | N/A | 2021-12-01 |
| Completed | Normative Cardiovascular Magnetic Resonance Values for Measurement of Cardiovascular Structure and Function at Healthy Volunteers | — | 2021-10-05 |
| Completed | Bespoke vs Standard Instrumentation in TKR Knee Osteoarthritis | N/A | 2021-09-21 |
| Unknown | PAIR (Paracetamol and Ibuprofen Research) Pilot Trial Patent Ductus Arteriosus | Phase 2 / Phase 3 | 2021-09-03 |
| Completed | Endoscopically-delivered Purastat to Treat Bleeding Caused by Radiation Proctopathy Radiation Proctopathy | N/A | 2021-07-22 |
| Completed | Evaluating Bubble-PAPR for Healthcare Workers Covid19 | — | 2021-02-24 |
| Completed | Timing of Stoma Closure in Neonates Enterocolitis, Necrotizing, Atresia; Bowel, Gastroschisis | — | 2021-02-17 |
| Unknown | Longitudinal Changes in Serum KL-6 in IPF Idiopathic Pulmonary Fibrosis | — | 2021-02-01 |
| Withdrawn | T-MACS Decision Aid: a Randomized, Controlled Point of Care Trial Heart Attack, Chest Pain, Acute Coronary Syndrome | N/A | 2021-01-01 |
| Completed | Comparison of Day and Night Closed-loop With Faster-acting Insulin Aspart With Insulin Aspart Diabetes Mellitus, Type 1 | N/A | 2020-12-23 |
| Completed | The Efficacy and Mechanism of Trientine in Patients With Hypertrophic Cardiomyopathy Hypertrophic Cardiomyopathy | Phase 2 | 2020-12-01 |
| Completed | Transdermal Fluid Removal in Fluid Overload Heart Failure, Odema | N/A | 2020-11-11 |
| Recruiting | Integrated Diagnostics for Early Diagnosis of Liver Disease Non-Alcoholic Fatty Liver Disease, Non-alcoholic Steatohepatitis, Alcoholic Liver Disease | — | 2020-10-21 |
| Completed | Core Outcome Set for Head, Neck and Respiratory Disease in Mucopolysaccharidosis II Mucopolysaccharidosis Type II | — | 2020-09-28 |
| Withdrawn | Paramedic Experiences and Perceptions of Training for Participation in Research: the PREPARE Study Staff Attitude | — | 2020-09-09 |
| Completed | Virtual Reality for Children's Blood Sampling Pain, Fear, Child, Only | — | 2020-08-03 |
| Completed | Facilitating AcceLerated Clinical Validation Of Novel Diagnostics for COVID-19 (FALCON-C19) Coronavirus Infection, COVID-19 | — | 2020-05-19 |
| Recruiting | The Impact of Abdominal Wall Closure Technique on Incidence of Incisional Hernia in Kidney Transplantation Surgery--Complications | N/A | 2020-03-10 |
| Completed | Medication Compliance in the Paediatric Uveitis Population Reported by the Patients and Parents Uveitis | — | 2020-02-14 |
| Completed | Web-based Adherence Information Integrated Nurse-led Monitoring Clinic Short Stature, Growth Hormone Treatment | — | 2020-01-24 |
| Completed | Flash-glucose Monitoring in Sub-optimally Controlled Type 1 Diabetes (FLASH-UK) Diabetes Mellitus, Type 1 | N/A | 2020-01-09 |
| Completed | Does Improved Ability to Achieve Single Leg Stance Lead to a More Efficient Gait Pattern in Adults With Acquir Acquired Brain Injury | N/A | 2019-12-24 |
| Completed | Using the Speckle Doppler to Quantify Blood Flow in Kidney and Pancreas Grafts Kidney Transplant Failure and Rejection | — | 2019-12-06 |
| Completed | Non-linear Frequency Compared to Conventional Processing in Patients With and Without Cochlear Dead Regions. Sensorineural Hearing Loss, Bilateral, Cochlear Hearing Loss | N/A | 2019-11-20 |
| Active Not Recruiting | Shoulder Surgery Traditional vs Accelerated Rehabilitation Trial Rotator Cuff Tear, Rotator Cuff Tear or Rupture, Not Specified as Traumatic | N/A | 2019-10-18 |
| Unknown | What is the Workload Burden Associated With Using the Triage HF+ Care Pathway? Heart Failure | — | 2019-09-06 |
| Unknown | Manchester Lung Health Study Lung Cancer | — | 2019-08-20 |
| Completed | Whole-body Vibration in Children With Neurofibromatosis Type 1 Neurofibromatosis Type 1, Muscle Weakness | N/A | 2019-07-22 |
| Completed | Diagnostic Performance of Smart Supra Perimetry (The DPSSP Study) Glaucoma, Suspect, Glaucoma | N/A | 2019-06-11 |
| Unknown | Changes in the Microbiome Associated With Transplantation Microbiota | — | 2019-05-24 |
| Unknown | A Study of Migalastat in Fabry Disease Fabry Disease | — | 2019-05-16 |
| Completed | Automated Low Dose Risk Assessment Mammography (ALDRAM) Breast Cancer | N/A | 2019-02-22 |
| Completed | The Use of Novel Diagnostic Tools to Increase Detection of Early Fibrosis in Cystic Fibrosis Related Liver Dis Cystic Fibrosis, Liver Fibroses, Cystic Fibrosis Liver Disease | — | 2019-02-15 |
| Completed | A Functional Comparison of Two TKR Designs Knee Osteoarthritis | N/A | 2019-02-06 |
| Unknown | Motivations and Barriers to Participating in Ophthalmology Research Projects Eye Diseases | — | 2019-01-21 |
| Completed | Does the "TOOKIE Vest" Reduce Line Fall Out Rate in Children? Childhood Cancer | N/A | 2019-01-15 |
| Active Not Recruiting | The Pre-hospital Evaluation of Sensitive Troponin (PRESTO) Study Chest Pain, Acute Coronary Syndrome, Heart Attack | — | 2018-10-16 |
| Completed | Study of the Effect of Prehabilitation on Markers of Sarcopenia in Patients Undergoing Pancreatoduodenectomy f Pancreatic Ductal Adenocarcinoma | — | 2018-10-04 |
| Completed | Breath Analysis in Patients With Suspected Sarcoidosis: The VOCs-IS Study Pulmonary Sarcoidosis | — | 2018-10-01 |
| Completed | Comparison of MCO HD on Markers of Vascular Health Compared With On-Line Haemodiafiltration End Stage Renal Disease, Cardiovascular Diseases, Inflammation | N/A | 2018-09-14 |
| Completed | Postnatal Enalapril to Improve Cardiovascular fUnction Following Preterm Pre-eclampsia Cardiovascular Diseases, Pre-Eclampsia Onset Less Than 37 Weeks (Diagnosis) | Phase 2 | 2018-09-05 |
| Completed | Comparison of Real-tiMe ContInuous gLucosE moNitoriNg With Self-monitorIng of Blood Glucose in Young AduLts Wi Diabetes Mellitus, Type 1 | N/A | 2018-07-16 |
| Completed | A Pilot Study of Ultrasound-guided Vacuum-assisted Excision of Breast Cancers Breast Cancer | — | 2018-06-25 |
| Completed | Comparing the Effectiveness of a Safety Intravenous Cannula With a Standard Intravenous Cannula in Neonates Preterm Infant | N/A | 2018-06-20 |
| Completed | The Roles of Hilotherapy in the Management of Epistaxis and Nasal Fractures Epistaxis | N/A | 2018-05-01 |
| Completed | Packing of Perianal Abscess Cavities Perianal Abscess, Perianal Infections, Peri Rectal Abscess | N/A | 2018-02-14 |
| Completed | Evaluating Face-Recognition Technology in Syndrome Diagnosis Multiple Anomalies, Dysmorphic Features, Inborn Errors of Metabolism | N/A | 2018-01-30 |
| Completed | Interstitial Lung Disease Within a Lung Cancer Screening Interstitial Lung Disease | — | 2017-11-11 |
| Withdrawn | The Role of Biomarkers in Inherited Cardiac Conditions Inherited Cardiac Conditions | — | 2017-11-02 |
| Completed | DVT After Cardiac Procedure Thromboembolism, Deep Vein Thrombosis | — | 2017-10-20 |
| Completed | Comparison of Mesh Fixation Techniques in Elective Laparoscopic Repair of Incisional Hernia - ReliaTack™ v Pro Incisional Hernia, Hernia, Abdominal Hernia | N/A | 2017-07-20 |
| Unknown | LATITUDE An Observational Study of Patient Choice and the Urethral Bulking Agent, Bulkamid® Urinary Incontinence, Stress Urinary Incontinence | — | 2017-06-12 |
| Completed | Biomarkers in HF: Circulating Biomarkers of Fibrosis and Cardiovascular Disease Heart Failure With Preserved Ejection Fraction | — | 2017-03-02 |
| Completed | The Efficacy and Safety of Pirfenidone in Patients With Heart Failure and Preserved Left Ventricular Ejection Cardiac Failure | Phase 2 | 2017-03-02 |
| Completed | Wireless Handheld 8-lead ECG Device Performance in Heart Patients (Rapid Rhythm) Atrial Fibrillation, Heart Murmurs | N/A | 2017-01-24 |
| Completed | Peptide GAM Immunoadsorption Therapy in Autoimmune Membranous Nephropathy Autoimmune Membranous Nephropathy | N/A | 2016-11-30 |
| Completed | A Single-centre Prospective Study to Explore the Role of Frailty in Patients With Multiple Myeloma. Multiple Myeloma | — | 2016-10-03 |
| Completed | Transcapillary Plasma Refill in Advanced Chronic Kidney Disease Haemodynamic Instability | N/A | 2016-09-01 |
| Completed | Breast Reconstruction Outcomes With and Without StratticE Breast Neoplasms | — | 2016-08-19 |
| Completed | Magnetic Seed Localisation of Breast Cancers Breast Cancer | N/A | 2016-07-06 |
| Completed | Validation of a Virtual Model of Service Delivery for Choroidal Nevi Choroidal Nevus | — | 2016-06-08 |
| Completed | Immediate Loading of Bone Anchored Hearing Devices Hearing Loss | N/A | 2016-06-01 |
| Completed | Correlation of Anal Acoustic Reflectometry Parameters With Degree of Rectal Intussusception and Prolapse Pelvic Floor Disorders | — | 2016-04-01 |
| Completed | The Use of Home-monitoring and mHealth Systems to Predict Asthma Control and the Occurrence of Asthma Exacerba Asthma | — | 2016-04-01 |
| Completed | Comparing Gamification With Remote Monitoring Against Standard Rehabilitation, for Patients After Arthroscopic Shoulder Impingement Syndrome, Subacromial Impingement Syndrome | N/A | 2016-03-29 |
| Completed | Does Intra-operative MarginProbe Use Reduce Re-excision Rates? Breast Cancer | N/A | 2016-03-22 |
| Completed | Does Adding Spinal Anaesthesia to a General Anaesthetic Technique Influence Readiness for Discharge in Patient Surgery | N/A | 2016-03-16 |
| Completed | Evaluation of the Rectal Reflex Using Anal Acoustic Reflectometry Pelvic Floor Dysfunction | — | 2016-02-01 |
| Completed | Breast Cancer - Anti-Progestin Prevention Study 1 Breast Cancer | Phase 2 | 2016-01-22 |
| Completed | The Long Term Outcomes of Micronutrient Antioxidant Supplementation in Patients With Chronic Pancreatitis Chronic Pancreatitis | — | 2015-11-30 |
| Completed | Evaluation of the Fast Fill Technique for Anal Acoustic Reflectometry (AAR) in the Incontinent Anal Sphincter Faecal Incontinence | — | 2015-11-01 |
| Completed | Flow-cycled Ventilation in Preterm Infants Neonatal Respiratory Distress Syndrome | N/A | 2015-09-01 |
| Completed | BOne Dysfunction in Donor NEphrectomieS Renal Failure, Kidney Donors | — | 2015-07-29 |
| Completed | The Manchester Short Splint in the Rehabilitation of Zone II Flexor Tendon Repairs Tendon Injuries | N/A | 2015-06-01 |
| Completed | Colorectal Cancer With Liver-limited Synchronous Metastases: an Inception Cohort Study of Standardised Care Pa Colorectal Neoplasms, Liver Neoplasms, Neoplasm Metastasis | — | 2015-05-20 |
| Completed | Assessing the Effects of Mechanical Unloading on Repair Version-1 Heart Failure, Transplant; Failure, Heart | — | 2015-01-15 |
| Active Not Recruiting | The UHSM Cardiovascular Magnetic Resonance Study Cardiovascular Diseases | — | 2015-01-05 |
| Completed | TEP Versus Open Minimal Suture Repair for the Sportsman's Groin Hernia | N/A | 2014-12-03 |
| Withdrawn | Does Cardiopulmonary Bypass Change Olfaction? Anosmia | — | 2014-10-01 |
| Completed | 2014TP001 - Assessing the Biology of the Injured Lung - Version 1 Respiratory Diseases | — | 2014-08-29 |
| Completed | Characterisation of Heart Involvement in Fabry Disease With T1 Mapping Fabry Disease | — | 2014-03-12 |
| Completed | Effect of Implant Position on Magnetic Resonance Image Distortion Neurofibromatosis Type 2 | N/A | 2014-02-03 |
| Recruiting | Abnormal Lipids - Causes and Effects Hypertriglyceridaemia | — | 2014-01-23 |
| Terminated | Surviving Aneurysm Surgery: A Pilot Study on Exercise Training in Abdominal Aortic Aneurysm Patients Abdominal Aortic Aneurysm, Aortic Disease, Vascular Disease | N/A | 2013-06-01 |
| Withdrawn | Neuroplastic Changes Seen in Cochlear Implants With Preserved Hearing Hearing Loss | N/A | 2013-05-01 |
| Completed | A Validation Study of the Dx-pH Probe in Children for the Detection of Extra-oesophageal Reflux Gastro-oesophageal Reflux | N/A | 2013-03-22 |
| Completed | The Effectiveness of Portable Electronic Vision Enhancement Systems (p-EVES) for Near Vision in Visual Impairm Moderate or Severe Vision Impairment, Both Eyes | N/A | 2013-02-01 |
| Completed | The Feasibility, Acceptability and Clinical Utility of a New Remote-mobile Technology Intervention (ASARM) for Chronic Fatigue Syndrome | N/A | 2013-01-01 |
| Withdrawn | Sub-threshold Photocoagulation of Diabetic Macular Oedema Diabetic Macular Oedema | N/A | 2012-10-01 |
| Withdrawn | Panretinal Photo-stimulation in Proliferative Diabetic Retinopathy Severe Non-proliferative Diabetic Retinopathy | N/A | 2012-10-01 |
| Recruiting | Paraoxonase and HDL Qualities in Glycaemia and Inflammation Diabetes Mellitus, Bariatric Surgery Candidate | — | 2012-07-05 |
| Completed | Effect of Septal Versus Apical Pacing- a Comparative Study Using Cardiac MRI Ventricular Dysfunction, Ventricular Remodelling | N/A | 2012-02-01 |
| Completed | Scoring Method for Describing the Position of a Tracheostomy Tube Tracheostomy | — | 2011-07-01 |
| Completed | Manchester Antenatal Vascular Service Vascular Disease | — | 2011-07-01 |
| Completed | Action Medical Research Learning Disabilities | — | 2011-02-01 |
| Completed | Lidocaine: Effect of Lidocaine in Chronic Cough Chronic Cough | Phase 4 | 2011-02-01 |
| Completed | Novel Endpoints in Cough Challenge Testing Chronic Obstructive Pulmonary Disease, Asthma, Healthy | — | 2011-01-01 |
| Completed | The Role of Respiratory Viruses in Exacerbations of Cystic Fibrosis in Adults Cystic Fibrosis | — | 2010-12-01 |
| Completed | Telephone Consultation as a Substitute for Routine Out-patient Face-to-face Consultation for Children With Inf Crohn's Disease, Ulcerative Colitis | N/A | 2010-07-01 |
| Completed | New Ultrasound Parameters for Predicting Birthweight Fetal Development | — | 2010-07-01 |
| Completed | Effect of Tredaptive on Serum Lipoproteins and Inflammatory Markers Hypercholesterolemia | Phase 4 | 2010-06-01 |
| Completed | Cough Responses to Tussive Agents in Health and Disease Chronic Obstructive Airway Disease, Asthma, Chronic Cough | — | 2009-11-01 |
| Completed | Study of The Effects of Testosterone in Frail Elderly Men Frailty, Sarcopenia | Phase 4 | 2004-10-01 |
| Completed | A Trial of Pentoxifylline for the Treatment of Recurrent Aphthous Stomatitis Recurrent Aphthous Stomatitis | N/A | 1996-06-01 |