Clinical Trials Directory

Trials / Sponsors / National Institute of Environmental Health Sciences (NIEHS)

National Institute of Environmental Health Sciences (NIEHS)

NIH · 182 registered clinical trials19 currently recruiting.

StatusTrialPhaseStarted
RecruitingFAST for DM - Fatty Acid Supplementation Trial (FAST) for Dermatomyositis (DM)
Dermatomyositis (DM), Juvenile Dermatomyositis (JDM)
Phase 22026-04-22
Not Yet RecruitingA Natural History of Cardiometabolic Disease Among US Bhutanese: Developing the Cross-Sectional Bhutanese Comm
Cardiometabolic Risk Factors, Mental Health
2026-04-22
Not Yet RecruitingA Natural History of Genetic and Environmental Predictors of Pubertal Timing Among Youth With Obesity
Obesity
2026-04-22
RecruitingH01 in Adults With Interstitial Lung Disease (The SOLIS Study)
Interstitial Lung Disease, Idiopathic Pulmonary Fibrosis, Lung Diseases, Interstitial
Phase 22025-05-05
RecruitingNIEHS Repository of Stored Biological Samples for Future Use
Normal Physiology
2024-07-15
RecruitingObservation of Environment and Reproductive-Endocrine Effects
Hypogonadism, Hypergonadism, Precocious Puberty
2024-07-01
RecruitingWomen s Health Awareness Community Resiliency, Environmental Action and Collaborations for Health (REACH) Equi
Mental Health
2023-06-30
CompletedThe Investigation of Vitamin D and Menstrual Cycles Trial, the inVitD Trial: A Phase II Clinical Trial
Reproductive Issues
Phase 22023-03-17
Enrolling By InvitationMinipuberty of Infancy and the Timing of Pubertal Development in Adolescence: a Follow-up of the Infant Feedin
Puberty
2022-10-10
Enrolling By InvitationCOVID-19 Experiences in the SELF Cohort
COVID-19
2022-06-17
RecruitingNatural History of the Human Biological Response to Environmental Exposure and Injury
Inflammation, Normal Controls, Metabolic Disease
2021-11-16
WithdrawnRapid Acquisition of Pre- and Post-Incident Disaster Data
Biological Specimens
2021-01-27
Active Not RecruitingFactors Influencing Fertility or Pregnancy Health
Menstrual Cycles, Conception, Early Pregnancy Loss
2020-10-19
CompletedSerological Surveillance for COVID-19 in Central North Carolina
COVID-19
2020-08-24
CompletedProspective Natural History Study of Smoking, Immune Cell Profiles, Epigenetics and COVID-19
COVID-19
2020-06-01
RecruitingReproductive Axis Maturation in the Early Post-Menarchal Years
Reproductive Physiological Processes, Pediatrics, Adolescent Health
2019-12-19
WithdrawnCollection of Biological and Environmental Samples and Clinical Data From Anonymous Adult Men and Women for Qu
Laboratory Assay
2019-11-18
CompletedCytochrome P450 Epoxygenase Pathway Regulation of Macrophage Function
Polymorphism, Lung Inflammation
2019-01-08
CompletedStudy of Exposure to Chemicals in Consumer Products
Product Use
2018-08-07
CompletedQualitative Assessment of the Work-Sleep Relationship
Sleep Health
2018-05-08
CompletedSodium Thiosulfate for Treatment of Calcinosis Associated With Juvenile and Adult Dermatomyositis
Dermatomyositis, Idiopathic Inflammatory Myopathies
Phase 2 / Phase 32017-10-05
CompletedCaREFREE Study (Calorie Restriction, Environment and Fitness: Reproductive Effects Evaluation Study)
Hormones
N/A2017-01-12
RecruitingInvestigating the Impact of Obesity on Pubertal Development in Girls
Obesity, Puberty, Normal Physiology
2015-12-15
RecruitingNHALES (Natural History of Asthma With Longitudinal Environmental Sampling)
Asthma
2015-09-10
WithdrawnInhaled Nanosilver Study
Inflammatory Disease
2015-04-03
WithdrawnDHB Supplement Interaction Study
Healthy Volunteers
2014-10-03
CompletedEnvironmental Risk Factors for Myositis in Military Personnel
Dermatomyositis, Adult Polymyositis, Inclusion Body Myositis
2014-03-13
CompletedGenes Associated With Bronchopulmonary Dysplasia and Retinopathy of Prematurity
Bronchopulmonary Dysplasia, Retinopathy of Prematurity, Prematurity
2013-06-24
CompletedThe COX-2 Gene and the Immune System
Allergic Inflammation, Asthma
2013-05-02
CompletedEnvironmental Polymorphisms Registry Health and Exposures Survey
Diabetes, Heart Disease, Asthma
2012-08-25
RecruitingStudy of the Effect of Innate on the Inflammatory Response to Endotoxin
Asthma, Atherosclerosis, Metabolic Syndrome
2012-07-30
CompletedBisphenol A Controlled Exposure Study
Healthy Volunteers
Phase 12012-07-18
CompletedStudy of the Effect of SNPs in p53 and p53 Response Elements on the Inflammatory Response to DNA Damage
HIV-1 Seropositive, Inflammation, Cancer
2012-05-21
RecruitingInherited Reproductive Disorders
Genetic Disorder, Infertility, Hypogonadism
2012-04-25
CompletedHormonal Regulation of Puberty and Fertility
Endocrine Disease, Infertility, Hypogonadism
2012-04-25
CompletedTGF-(Beta) and Susceptibility to RSV
Asthma
2012-03-19
CompletedBlood Vessel Study
Cardiovascular Disease
2012-03-01
WithdrawnChildhood Asthma Reduction Study
Asthma
N/A2011-09-04
CompletedAgricultural Health Study Follow-up
Asthma, Parkinson's Disease
2011-07-05
Active Not RecruitingGulf Long-Term Follow-Up Study
Cardiovascular Disease, Hematologic Diseases, Immunologic Disease
2011-03-24
RecruitingEnvironmental Risk Factors for the Anti-synthetase Syndrome
Myositis, Dermatomyositis, Polymyositis
2011-02-09
WithdrawnBPA Biomonitoring Study in Cashiers
Bisphenol A
2011-01-10
CompletedThe Role of Glucocorticoid Receptor SNPs in Receptor Function and Metabolic Disease
Glucose Homeostasis, Protein Metabolism, Lipid Metabolism
2010-09-30
RecruitingPersonalized Environment and Genes Study
Diabetes, Heart Disease, Asthma
2010-05-26
CompletedA Follow-up of the Early Pregnancy Study Cohort.
Gestational Age, Time to Pregnancy, Early Pregnancy Loss
2010-05-05
CompletedSample Collection Registry for Quality Control of Biological and Environmental Specimens and Assay Development
Exposure
2010-03-02
CompletedShanghai Parkinson's Study
Parkinson's Disease
2009-10-14
RecruitingImmune Cell Response to Stimuli
Inflammation
2009-07-13
CompletedStudy of DDT and Loss of Clinically-Recognized Pregnancies in South Africa
Spontaneous Abortion, Malaria, Pregnancy Outcome
2009-06-01
CompletedIndoor Woodsmoke PM and Asthma
Asthma
Phase 32008-12-01
WithdrawnMolecular Markers of Human Sperm Function
Infertility, Reproduction, Reproductive Techniques, Assisted
2008-10-01
CompletedLung Mucus Hypersecretion and NQO1
Environmental Exposure, Ozone, Air Pollution
2008-08-01
CompletedFunctional Implications of TNF
Bronchitis
2008-08-01
CompletedBiomarker Analysis of Stress
Sepsis
2007-10-01
CompletedPCOS Twin Study - Environmental Factors in the Development of Polycystic Ovary Syndrome, Phase 2
Polycystic Ovary Syndrome
2007-02-27
CompletedOral Bacteria and Allergic Disease in Children
Asthma, Rhinitis, Eczema
2007-02-01
CompletedChildren With Asthma in New Orleans After Hurricane Katrina
Asthma, Allergies
2007-01-19
CompletedThe Influence of Breast Cancer Risk and Risk Perception on Lifestyle Behaviors Among Women With a Family Histo
Breast Neoplasms
2006-10-24
CompletedConfirmation of Self-Reported Incident ALS Cases in the AARP-Diet and Health (AARP-DH) Cohort
Amyotrophic Lateral Sclerosis
2006-09-11
CompletedParkinson's Genes and Environment Study
Parkinson's Disease
2006-08-21
CompletedAmbient Air Pollution, Preeclampsia, and Preterm Delivery
Preeclampsia, Preterm Delivery
2006-07-01
CompletedInfluence of Social and Environmental Factors on Women's Reproductive Function in a Maya Community of Guatemal
Early Pregnancy
2006-04-13
CompletedGenetic Measurements in Blood Cells of Children Taking Adderall or Methylphenidate
Attention Deficit Hyperactivity Disorder, ADHD
2005-12-07
CompletedStudies of the Natural History and Pathogenesis of Autoimmune/Connective Tissue Diseases
Autoimmune/Connective Tissue Diseases, Idiopathic Inflammatory Myopathies, Polymyositis
2005-07-13
CompletedPathogenesis and Genetics of Environmental Asthma Ozone Study
Asthma, Inflammation
2005-07-01
CompletedProspective Lung Transplant Database for Genetic Research
Lung Transplantation Rejection
2005-06-23
CompletedCan Immune Parameters Predict Acute and Chronic Rejection in Lung Recipients?
Lung Transplantation
2005-06-23
CompletedMechanisms of Lung Allograft Rejection
Lung Transplant, Chronic Allograft Rejection
2005-06-23
CompletedDust Mite Allergen Reduction Study
Allergy
Phase 22005-06-06
CompletedChildren's Exposures/Health Effects/Diesel Exhaust
Asthma, Airway Inflammation
2005-03-01
CompletedPredictive and Protective Factors in the Cause of Diabetes - A Study in Twins
Diabetes, Type 1 Diabetes
2005-02-01
CompletedHormonal Changes in Early Pregnancy
Pregnancy
2005-01-18
CompletedCockroach Allergen Reduction by Extermination Alone in Low-Income, Urban Homes: A Randomized Control Trial
Allergens
Phase 12004-08-12
CompletedEffects of Anti-HIV Therapy on Red Blood Cells of HIV-infected Mothers and Their Infants
Cord Blood
2004-06-25
CompletedDiet and Genetic Damage
Diet
2004-04-21
CompletedDisease Progression and Activity in Patients With Systemic Lupus Erythematosus
Lupus
2003-12-16
CompletedEffects of Infant Diets on Estrogen Activity and Development
Hormone
2003-08-26
CompletedThe Sister Study: Genetic and Environmental Risk Factors for Breast Cancer
Breast Cancer
2003-08-01
CompletedExposure to Neurotoxins as Risk Factors for ALS
ALS
2003-06-03
CompletedStudy of Infant Diets on Estrogen Activity and Development
Infant Formula, Estrogen Activity
2003-05-05
CompletedNitric Oxide, LPS and the Pathogenesis of Asthma Phase 1
Healthy, Asthma
2003-05-01
CompletedStudy of Families With Twins or Siblings Discordant for Rheumatic Disorders
Rheumatoid Arthritis, Systemic Lupus Erythematosus, Idiopathic Inflammatory Myopathies
2003-04-21
CompletedHOME Study (Health Outcomes and Measures of the Environment Study)
Environmental Exposures, Child Development, Lead and Injury Reduction
N/A2003-03-01
CompletedOrganochlorine Exposure in Relation to Timing of Natural Menopause
Menopause
2003-03-01
CompletedDietary and Genetic Factors in Asthma & Chronic Bronchitis in a Cohort of Chinese Singaporeans
Chronic Bronchitis, Asthma
2002-11-01
CompletedMR Assessment of Brain Function Altered by Lead Exposure
Lead Exposure
2002-10-01
CompletedPrevention of Tumor Spread Due to Lung Cancer Surgery
Non-Small Cell Lung Cancer
2002-09-24
CompletedExposure to Neurotoxins as Risk Factors for Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis, ALS
2002-08-06
CompletedEffect of Environmental Exposures on the Egg Fertilizing Ability of Human Sperm
Male Infertility, Testicular Diseases, Urologic and Male Genital Diseases
2002-08-01
TerminatedReducing Farmworkers Exposure to Agricultural Chemicals
Pesticide Safety
N/A2002-07-01
CompletedConfirmation of Systemic Autoimmune Diseases in the Agricultural Health Study
Autoimmune Disease
2002-04-02
CompletedHealthy Environments Partnership
Cardiovascular Health
2002-04-01
CompletedWork and Health Disparities Among Rural Women
Tendonitis, Carpal Tunnel Syndrome, Cumulative Trauma Disorders
2002-03-01
CompletedPostpartum Uterine Regression
Uterine Leiomyoma
2001-12-06
CompletedEarly Exposure to Lead and Adult Antisocial Outcomes
Lead Poisoning
2001-11-01
CompletedIdentifying Residential Hazards Using Home Test Kits
Poisoning, Lead
2001-10-01
CompletedEarly Life Factors and Respiratory Health in Mexico City Children
Respiratory Ilness
2001-10-01
CompletedNIEHS/UNC Environmental Polymorphism Study
Genetic Polymorphisms
2001-10-01
CompletedThe Norwegian Mother and Child Study - Environmental Specimen Collection
Environmental Determinants, Pregnancy
2001-10-01
CompletedChildhood Autism Risks From Genetics and the Environment (The CHARGE Study)
Autism, Developmental Disabilities
2001-09-01
CompletedOutdoor Allergen Exposure, Sensitivity, and Acute Asthma
Asthma
2001-07-01
CompletedGene-Environment Interaction in Prostate Cancer
Prostate Cancer
2001-07-01
CompletedFibroid Growth Study
Uterine Leiomyomas
2001-06-27
CompletedThe Genetics of Environmental Asthma
Asthma
N/A2001-06-01
CompletedEffect of the Antiandrogen DDE on Anthropometric Measures at Birth
DDT
2001-05-14
CompletedOxidative Stress and Hemodialysis Access Failure
End Stage Renal Disease, Hemodialysis
2001-05-01
CompletedPrevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic
Zinc Fingers Proteins
2001-04-18
CompletedLupus Nephritis: Role of Environmental and Occupational Exposures
Lupus Nephritis
2001-04-16
CompletedFarming and Movement Evaluation Study (FAME)
Parkinson's Disease, Movement Disorders
2001-04-01
CompletedSocio-economic Status and Age-related Disability in a Biracial Community
Healthy
2001-04-01
CompletedCatechol Thioethers in Parkinson's Disease
Parkinson's Disease
2001-03-01
CompletedPesticide Exposure Pathways for Farmworker Children
Poisoning
2001-03-01
CompletedDietary Calcium Supplementation to Reduce Blood Lead in Pregnancy
Lead, Blood, Pregnancy, Bone Resorption
N/A2001-01-01
CompletedEnvironmental Factors in the Development of Polycystic Ovary Syndrome
Polycystic Ovary Syndrome
2000-12-01
CompletedA Pilot Study to Evaluate the Efficacy of Refined Methods to Mitigate Indoor Allergens in North Carolina and B
Hypersensitivity
2000-10-19
CompletedMolecular Epidemiology of Parkinson's Disease
Parkinson Disease
2000-09-01
CompletedParkinson's Diseases Susceptibility Genes and Pesticides
Parkinson's Disease
2000-09-01
CompletedAsthma & Exposure to Peaks in Particulate Air Pollution
Asthma
2000-09-01
CompletedGeographic Modeling of Traffic and Asthma Rates
Asthma
2000-09-01
Completedp450 Mediated Lung Toxicity
Pulmonary Disease
2000-09-01
CompletedNasal Irritation Study: Individual Factors in Nasal Irritant Sensitivity
Rhinitis, Allergic, Nonseasonal
N/A2000-09-01
CompletedBrain Neoplasms, Leukemia and Petrochemical Exposures
Leukemia, Brain Neoplasm
2000-08-01
CompletedReducing Pesticide Exposure in Minority Families
Disorders of Environmental Origin
N/A2000-07-01
CompletedIncidence and Mortality of Childhood Cancer Among Children of Farmer Pesticide Applications
Pesticide Exposure
2000-06-28
CompletedSocial Network Based Intervention to Reduce Lead Exposure Among Native American Children
Lead Poisoning
N/A2000-06-01
CompletedAsthma Severity in Children and Environmental Agents
Asthma
2000-05-01
CompletedRole of the Toxic Metal Cadmium in the Mechanism Producing Infertility With a Varicocele
Varicocele, Male Infertility, Hypospermatogenesis
2000-05-01
CompletedVulnerability of the Fetus/Infant to PAH, PM2.5 AND ETS.
Pregnancy
2000-02-01
CompletedCardiac Vulnerability in Potentially Susceptible Patients
Heart Disease
1999-10-01
CompletedEnvironment and Reproductive Health; Human Exposure to Bisphenol A, Phthalates and Fertility and Pregnancy Out
Infertility
1999-10-01
CompletedEffects of Pesticide Exposure on Neurodevelopment/Growth/Respiratory Health
Environmental Exposure
N/A1999-10-01
CompletedPrenatal PCB Exposure
Maternal Exposure
1999-09-01
CompletedOzone and Rhinovirus-Induced Disease in Asthmatics
Asthma
1999-09-01
CompletedStudy for Future Families
Pregnancy
1999-09-01
CompletedFluorescence Bronchoscopy and Molecular Characterization of Abnormal Bronchial Lesions: Novel Approaches for E
Cancer
1999-07-29
CompletedCollaborative Study of 1,3 Butadiene Biomarkers
Cancer
1999-07-01
CompletedAttention Deficit Disorder and Exposure to Lead
Attention Deficit Disorder
1999-06-01
CompletedCommunity Based Prevention/Control Project
Poisoning
N/A1999-06-01
CompletedGenetic Susceptibility to Childhood Respiratory IIlness in Mexico City
Asthma
1999-05-15
CompletedCardiopulmonary Effects of Particulate Exposure
Respiratory Tract Diseases, Cardiac Diseases, Bronchitis
1999-03-01
CompletedPesticide Exposure and Health Status in North Carolina African American Male Farmers and Farm Workers
Pesticide Exposure
1999-01-27
CompletedStachybotrys Induced Hemorrhage in the Developing Lung
Idiopathic Pulmonary Hemorrhage
1999-01-01
CompletedA Cohort Study of Smoking Prevention and Health Promotion for Middle School Students in Wuhan, China
Asthma
1998-12-01
CompletedPollutant Altered Allergic Responses
Allergic Rhinitis, Allergy
1998-12-01
CompletedLead Exposure, Genetics, and Osteoporosis Epidemiology
Osteoporosis
1998-09-01
CompletedCardiovascular Vulnerability to Particulate Exposure
Heart Disease, Lung Disease
1998-09-01
CompletedAir Pollution and Implantable Cardioverter Defibrillators
Arrythmias
1998-09-01
CompletedBone Lead Levels and College Achievement Scores
Lead Poisoning
1998-09-01
CompletedFarm Work & Preterm Low Birthweight Among Hispanic Women
Infant, Low Birth Weight, Infant, Premature, Diseases
1998-08-01
CompletedProtection Against Benzene Toxicity
Leukemia, Aplastic Anemia
1998-07-01
CompletedOzone Exposure and Dose Delivered to Human Lungs
Lung Disease
1998-07-01
CompletedNational Survey of Lead and Allergen Hazards in Housing
Asthma, Allergy
1998-06-30
CompletedBladder Cancer Case Control Study of Arsenic in Water
Bladder Cancer
1997-10-01
CompletedCommunity-Based Environmental Health Intervention
Poisoning
N/A1997-10-01
CompletedHealth Effects of Early-Life Exposure to Urban Pollutants in Minority Children
Asthma, Development
1997-08-01
CompletedJohnston County ADHD Study: Environmental, Reporductive, and Familial Risk Factors for Attention-Deficit Hyper
Attention-Deficit Hyperactivity Disorder
1997-05-07
CompletedEarly Exposure to Lead and Adolescent Development
Lead Poisoning
1997-05-01
CompletedExposure, Dose, Body Burden and Health Effects of Lead
Lead Poisoning
1997-02-01
CompletedEnvironmental Contaminants and Infant Development
Mercury Poisoning, Lead Poisoning
1997-01-01
CompletedHormonal and Environmental Risk Factors for Developing Systemic Lupus Erythematosus: The Carolina Lupus (CLU)
Systemic Lupus Erythematosus
1996-12-17
CompletedExogenous Toxicants and Genetic Susceptibility in ALS
Amyotrophic Lateral Sclerosis
1996-09-01
CompletedPesticides--Health Fertility and Reproductive Risk
Birth Defects, Miscarriages, Cancer
1996-09-01
CompletedLead Mobilization & Bone Turnover in Pregnancy/Lactation
Lead Poisoning
1996-08-01
CompletedLead, Endocrine Disruption and Reproductive Outcomes
Lead Poisoning, Infertility
1996-08-01
CompletedRisk Factors for Uterine Fibroids: A Case Control Study
Uterine Fibroids
1995-11-01
CompletedSvangerskap, Arv, Og Miljo (Pregnancy, Heredity and Environment)
Birth Defects, Cleft Palate, Cleft Lip
1995-09-06
RecruitingAdult and Juvenile Myositis
Dermatomyositis, Polymyositis, Inclusion Body Myositis
1995-06-07
CompletedMolecular Epidemiology of Childhood Leukemia (Aka The California Childhood Leukemia Study)
Leukemia, Acute Myelocytic Leukemia, Acute Lymphoblastic Leukemia
1995-04-01
CompletedDichloroacetate Kinetics, Metabolism and Toxicology
Lactic Acidosis
1994-12-01
CompletedTreatment of Lead-Exposed Children Trial
Lead Exposure
Phase 31994-07-15
CompletedEstrogen Receptor Gene Mutations
Mutations, Hormones
1994-01-12
CompletedMechanisms of Inflammatory Liver Injury
Liver Diseases
CompletedOrganophosphate Pesticides and Human Reproductive Health
Fecundability, Spermatazoa Disorders, Menstruation Disorders
CompletedNevada Environmental Tobacco Smoke and Health Study
Cardiovascular Disease, Cancer
Phase 3
CompletedReproductive Effects of Pesticide, PCB and Mercury Exposure in Laotian Immigrants
Amenorrhea, Dysmenorrhea, Oligomenorrhea
CompletedMohawk Culture, Behavior, Toxicant Exposure and Health
Thyroid Diseases, Cognition Disorders
CompletedModulation of Benzene Metabolism by Exposure to Environment
Lung Diseases, Cancer
N/A
CompletedCommunity Organizing Network for Environmental Health
Asthma
N/A
CompletedHematotoxic Effects of Particulate Exposure
Cancer
CompletedReducing Indoor Allergen Exposures in Northern Manhattan and the South Bronx
Asthma, Allergy
N/A
CompletedHealth Effects of Particulate Acids in Late Adolescence
Airway Obstruction, Cough
CompletedBiomarkers of Benzene Exposure in Inner City Residents
Lung Disease, Cancer