Trials / Completed
CompletedNCT00015015
Dichloroacetate Kinetics, Metabolism and Toxicology
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 100 (planned)
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS) · NIH
- Sex
- All
- Age
- 3 Months – 65 Years
- Healthy volunteers
- Accepted
Summary
Dichloroacetate (DCA) is a product of water chlorination and a metabolite of certain industrial solvents, thus making it a chemical of environmental concern. However, DCA is also used as an investigational drug for treating various diseases of adults and children, at doses far greater than those to which humans are normally exposed in the environment. Our research involves how DCA is metabolized by healthy adults and by children with a fatal genetic disease, congenital lactic acidosis (CLA) who are treated with DCA.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Dichloroacetate |
Timeline
- Start date
- 1994-12-01
- Completion
- 2002-10-01
- First posted
- 2001-04-19
- Last updated
- 2006-09-04
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT00015015. Inclusion in this directory is not an endorsement.