Clinical Trials Directory

Trials / Completed

CompletedNCT00011453

Protection Against Benzene Toxicity

NQO1 in Protection Against Benzene Toxicity

Status
Completed
Phase
Study type
Observational
Enrollment
Sponsor
National Institute of Environmental Health Sciences (NIEHS) · NIH
Sex
All
Age
21 Years – 65 Years
Healthy volunteers
Accepted

Summary

We are investigating the role of an enzyme (NQO1) in protection against the bone marrow toxicity of the occupational and environmental toxicant benzene. All of the proposed studies involve use of human bone marrow cells in-vitro to define mechanisms of NQO1-mediated protection. Cells are obtained from healthy volunteers and protocols have undergone IRB review and approval.

Conditions

Timeline

Start date
1998-07-01
Completion
2001-06-01
First posted
2001-02-23
Last updated
2005-06-24

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT00011453. Inclusion in this directory is not an endorsement.