Clinical Trials Directory

Trials / Terminated

TerminatedNCT02633293

An Open Label Extension Study to Evaluate Inhaled Treprostinil in Adult PH With ILD Including CPFE

An Open-Label Extension Study of Inhaled Treprostinil in Subjects With Pulmonary Hypertension Due to Parenchymal Lung Disease

Status
Terminated
Phase
Phase 2 / Phase 3
Study type
Interventional
Enrollment
243 (actual)
Sponsor
United Therapeutics · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This is a multicenter, open-label trial to evaluate the safety and efficacy of inhaled treprostinil in subjects with pre-capillary pulmonary hypertension (PH) associated with interstitial lung disease (ILD) including combined pulmonary fibrosis and emphysema (CPFE). The study will include about 266 patients who completed all required assessments in the RIN-PH-201 study at approximately 100 clinical trial centers. The study will continue Your participation in this study is voluntary and will last until you discontinue from the study or the study ends. The study will continue until each subject reaches the Week 108 visit or until inhaled treprostinil become commercially available for patients with PH associated with ILD including CPFE (whichever is sooner).

Conditions

Interventions

TypeNameDescription
DRUGInhaled TreprostinilInhaled treprostinil up to 15 breaths (90 mcg) four times daily

Timeline

Start date
2016-09-15
Primary completion
2021-08-01
Completion
2021-08-01
First posted
2015-12-17
Last updated
2022-12-02
Results posted
2022-12-02

Locations

92 sites across 2 countries: United States, Puerto Rico

Source: ClinicalTrials.gov record NCT02633293. Inclusion in this directory is not an endorsement.