NCT04136223

Rheumatoid Arthritis-Associated Interstitial Lung Disease: Characterization of Lung Disease Progression

BERTHA Study: Rheumatoid Arthritis-Associated Interstitial Lung Disease: Characterization of Lung Disease Progression. A Multicenter, Observational Study

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: Hospital do Coracao · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

BERTHA study´s primary objective is to characterize Rheumatoid Arthritis-associated Interstitial Lung Disease (RA-ILD) progression and to define a combination of biomarkers, genetic and clinical variables capable of identifying patients at risk of RA-ILD progression

Detailed description

BERTHA is a multicentric, observational study that will enroll 100 RA-ILD patients to be followed for 2 years. Interstitial Lung Disease (ILD) progression will be ascertained by quantitative image analysis and functional parameters. Variables associated with progression with be identified. Additionally, RA-ILD endotypes will be investigated as well as their association with RA-ILD progression.

Conditions

• Rheumatoid Lung
• Rheumatoid Arthritis
• Interstitial Lung Disease
• Pulmonary Fibrosis

Timeline

• Start date: 2021-03-01
• Primary completion: 2024-05-31
• Completion: 2024-05-31
• First posted: 2019-10-23
• Last updated: 2023-06-29

Locations

5 sites across 1 country: Brazil