NCT04139356

The Effect of Spontaneous Respiration on Pulse-oximetry Measurements

The Effect of Spontaneous Respiration on Pulse-oximetry Measurements and Analysis of Variability Mechanisms

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 45 (estimated)
• Sponsor: Universidad Autonoma de Nuevo Leon · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This is a study designed to measure, characterize and describe changes on pulse-oxymetry values produced as a result of deep breaths in patients with stable chronic hypoxemic respiratory failure.

Detailed description

There is no standard way of measuring rest pulse-oxymetry in terms of depth of respiration. Rest pulse-oxymetry values are used in the clinical setting to make therapeutic decisions regarding the need of supplemental oxygen. The primary goal of this study is to measure the change of pulse-oxymetry values during an experimental protocol of 10 deep breaths during one minute in patients with chronic hypoxemia. 45 patients will be studied in this first phase. In a second phase, secondary goals will be to measure Vd/Vt vent, noninvasive cardiac output and CT densitometry during the same deep breaths protocol in a subset of 13 patients with the grater increase observed in the first phase of study.

Conditions

• Chronic Respiratory Disease
• COPD
• Interstitial Lung Disease

Interventions

Type	Name	Description
PROCEDURE	Deep breaths	Patients will undergo a 6 minutes protocol. Baseline: 1 minute normal breaths. Intervention: 1 minute with 10 deep breaths, 1 each 6 secs. Pulse-oxymetry will be continuously recorded.

Timeline

• Start date: 2019-09-01
• Primary completion: 2019-11-15
• Completion: 2019-12-15
• First posted: 2019-10-25
• Last updated: 2019-10-25

Locations

1 site across 1 country: Mexico