COPD

1,442 registered clinical trials studyying COPD — 177 currently recruiting.

Status	Trial	Sponsor	Phase
Not Yet Recruiting	RSV Vaccination to Reduce Recurrent AECOPD NCT07508644	Chinese University of Hong Kong	Phase 4
Not Yet Recruiting	Portable Positive Pressure Therapy Device NCT04452851	Koronis Biomedical Technologies	N/A
Not Yet Recruiting	The REVIVE Pivotal Study NCT07361653	Ryme Medical, Inc.	N/A
Not Yet Recruiting	A COPD Data Registry for Participants With Frequent Exacerbations NCT07059273	Hoffmann-La Roche	—
Not Yet Recruiting	Effectiveness of Pollution Monitoring in Clinical Exercise Rehabilitation NCT07500948	University of Leicester	N/A
Not Yet Recruiting	Hospital- and Home-Based Structured Pulmonary Rehabilitation in Recently Admitted COPD Patients: A Quasi-Exper NCT07197229	Assiut University	N/A
Recruiting	Turkish Validation of the Nijmegen Questionnaire in COPD NCT07344649	Saglik Bilimleri Universitesi	—
Not Yet Recruiting	Phase II Clinical Study to Evaluate the Efficacy and Safety of XKH001 Injection NCT07519499	Zhejiang Kanova Biopharmaceutical Co., LTD	Phase 2
Not Yet Recruiting	PEP Buddy in Pulmonary Rehabilitation NCT07404826	VA Office of Research and Development	N/A
Not Yet Recruiting	Mobile Health Self-Management Intervention for Patient With Chronic Obstructive Pulmonary Disease NCT07469904	Universitas Katolik Widya Mandala Surabaya	N/A
Active Not Recruiting	Home Oscillatory Positive Expiratory Pressure - Aerobic Exercise Rehabilitation Study NCT06970054	Sir Run Run Shaw Hospital	N/A
Recruiting	Emotional-distress-based Integrated Care Programme in Patients With Stable COPD NCT07524023	University of Zurich	N/A
Recruiting	Effect of Telenursing on Oral Health NCT07462221	Çanakkale Onsekiz Mart University	N/A
Not Yet Recruiting	A Multi Center Study Testing a New Implant for Adults With Severe Emphysema NCT07119229	Pulmair Medical, Inc.	N/A
Enrolling By Invitation	Probiotics in COPD: Effects on Symptoms, Lung Function, and Inflammation NCT07339280	University Hospital of Split	N/A
Not Yet Recruiting	Myofascial Release in Patients with Chronic Obstructive Pulmonary Disease NCT04260243	Cardenal Herrera University	N/A
Not Yet Recruiting	Shear Wave Elastography of Intercostal Muscles for the Non-invasive Assessment of the Work of BreathinG NCT07371754	Groupe Hospitalier du Havre	—
Not Yet Recruiting	Structured Review: To Optimise Management and Prevent Harm in COPD NCT07460154	Northumbria Healthcare NHS Foundation Trust	N/A
Not Yet Recruiting	Immuno-inflammatory Response of Erdosteine in COPD NCT07329946	Pierachille Santus, MD, PhD	N/A
Recruiting	Evaluating the Safety and Efficacy of dNerva Lung Denervation System in Patients With COPD NCT07051707	Nuvaira, Inc.	N/A
Recruiting	A Trial of the Implantable Artificial Bronchus 50 Flex in Patients With Severe Emphysema NCT07086339	Pulmair Medical, Inc.	N/A
Not Yet Recruiting	Bronchodilator Response in COPD and Asthma: Correlation Between Spirometry, IOS Indices, and Dyspnea Relief NCT07364188	Allergi- og Lungeklinikken, Elsinore	—
Not Yet Recruiting	Comparative Effects of Breather Device and Incentive Spirometer in Patients With COPD NCT07435532	Riphah International University	N/A
Not Yet Recruiting	Investigation of the Effects of Oxidized Antigens on the T-Cell Response and the Epigenetic Reprogramming of N NCT07386912	Research Center Borstel	—
Not Yet Recruiting	The Effect of Pursed-Lip Breathing Exercise on Anxiety and Physiological Parameters Post-Bronchoscopy in Patie NCT07361978	Fenerbahce University	N/A
Not Yet Recruiting	The Efficacy of Non-invasive Brain Stimulation on Cognitive Functions in Patients With Chronic Obstructive Pul NCT07332169	Shahad Abdulrahman Alkandari	N/A
Not Yet Recruiting	A Prospective Study of Cardiovascular Risk of Patients Admitted for Acute Exacerbation of COPD NCT07344285	Chinese University of Hong Kong	N/A
Recruiting	Closed Loop Oxygen Control in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Nasal High Fl NCT07222410	Fisher and Paykel Healthcare	N/A
Enrolling By Invitation	Inflammation and Oxidative Stress in COPD NCT07376161	Esra Yazar	—
Recruiting	Effect of IMT in Patients After Acute Exacerbations of COPD NCT07213128	KU Leuven	N/A
Not Yet Recruiting	The COPD CARE Study: Evaluating the Impact of a Virtual-First COPD Service on Major Cardiac and Respiratory Ev NCT06379529	NuvoAir Medical PC	N/A
Active Not Recruiting	High-Flow Nasal Cannula Versus Noninvasive Ventilation After Extubation in Patients With COPD and Mild Hyperca NCT07381686	Assiut University	N/A
Not Yet Recruiting	Impact of Home Non Invasive Ventilation in Patients With Chronic Obstructive Pulmonary Disease Discharged From NCT07198880	Assiut University	N/A
Recruiting	Assess Accuracy of Primary Care Asthma and COPD Diagnosis Using Oscillometry and FeNO vs Specialist Diagnosis NCT07245576	AstraZeneca	—
Not Yet Recruiting	The Effect of Bedside Whiteboard Use on Anxiety, Depression and Nursing Care in Chronic Obstructive Pulmonary NCT06929221	Agri Ibrahim Cecen University	N/A
Recruiting	How Nocturnal Hypoventilation Predicts Long-term Response to Non-invasive Ventilation in Hypercapnic COPD Pati NCT07414108	IRCCS Azienda Ospedaliero-Universitaria di Bologna	—
Not Yet Recruiting	Hemodynamic Effects of Inhaled Iloprost in PH-COPD (HOLLYWOOD) NCT07263958	University of Sao Paulo General Hospital	N/A
Enrolling By Invitation	Study on Home Obstructive Respiratory Exacerbations NCT06544928	Strados Labs, Inc.	—
Not Yet Recruiting	MOBoxy: MoblO2 to Maintain Oxygenation NCT07222592	National Jewish Health	N/A
Not Yet Recruiting	Serum Surfactant Protein-D as Predictor of Disease Severity in Hospitalized COPD Patients NCT07154953	Assiut University	—
Recruiting	Interprofessional Pharmacogenomics (IPGx) Registry and Repository NCT06726590	Texas A&M University	—
Recruiting	Ultrasound of the Diaphragm Excursion Ratio as Physiological Biomarker in Acute Exacerbations of Chronic Obstr NCT07259174	Isala	—
Recruiting	Implementation of a Sarcopenia Clinic to Diagnose and Treat Skeletal Muscle Loss Due to COPD NCT07059637	The Cleveland Clinic	N/A
Recruiting	Inhaler Trainer Efficacy Study NCT06461403	Koronis Biomedical Technologies	N/A
Recruiting	Comparison of Patients With COPD and PRISM NCT07249567	Karabuk University	—
Suspended	Home Non-Invasive Ventilation Targeting Expiratory Flow Limitation in Severe Hypercapnic COPD. NCT05109754	McGill University Health Centre/Research Institute of the McGill University Health Centre	N/A
Not Yet Recruiting	Mechanistic Studies of Chronic COPD Using Single-Cell Sequencing and Single-Cell Spatial Transcriptomics NCT07208123	Tongji University	—
Recruiting	Tumors and Respiratory System Diseases Due to Air Pollution: New Biomarkers of Exposure and Effects NCT06800586	IRCCS Azienda Ospedaliero-Universitaria di Bologna	—
Recruiting	Genetic Variation in IgG in Alpha 1 Antitrypsin Deficiency NCT07135427	University of Alabama at Birmingham	Phase 4
Completed	Motivation While Doing Physical Exercise in a Social Dual-task Virtual Environment NCT07050654	Istituto di Sistemi e Tecnologie Industriali Intelligenti per il Manifatturiero Avanzato	N/A
Not Yet Recruiting	Do Blood Tests Help to Decide Which Patients With Flares of Chronic Obstructive Pulmonary Disease (COPD) Need NCT06929767	Ottawa Hospital Research Institute	Phase 4
Not Yet Recruiting	Exploring the Anti-ageing Effects of Metformin in COPD NCT06999343	Fundación Instituto de Investigación Sanitaria de Navarra	Phase 3
Recruiting	Chronic Obstructive Pulmonary Disease and Asthma in Workers at Navanakorn Industrial Zone, Thailand NCT07383896	Thammasat University	—
Not Yet Recruiting	Respiratory Muscles in End-stage Lung Disease: Pathophysiological Processes & Clinical Consequences NCT06935825	University Medical Center Groningen	—
Withdrawn	Hyperpolarized Xenon Functional Lung Imaging in COPD Patients Undergoing Targeted Lung Denervation NCT05816616	Xemed LLC	—
Not Yet Recruiting	The Impact of a Weight Reduction Intervention on Clinical Outcomes in Patients With Obesity and COPD NCT07159594	Sahlgrenska University Hospital	N/A
Recruiting	COPD Resources, Education, and Activity Designed for You Study NCT07125053	Rush University Medical Center	N/A
Not Yet Recruiting	COPD Assessment Test Score and Perioperative Risk in COPD NCT07087626	Erzurum City Hospital	—
Recruiting	A Phase I Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics for a Single Dose of HRS-9 NCT07116915	Guangdong Hengrui Pharmaceutical Co., Ltd	Phase 1
Not Yet Recruiting	Digital Delivery of Living Well With COPD for Patient Education and Self-management - a Mixed-method Study NCT07031440	Insel Gruppe AG, University Hospital Bern	N/A
Not Yet Recruiting	Evaluation of the Effects on Carbon Dioxide (paCO2) of a New Oronasal Mask in Patients With Severe COPD Exacer NCT07081776	IRCCS Azienda Ospedaliero-Universitaria di Bologna	N/A
Completed	A Prognostic Model for COPD Complicated With Sarcopenic Obesity Based on Bioelectrical Impedance Phase Angle T NCT07136246	Fudan University	—
Not Yet Recruiting	Utilising Hull Lung Health Study Data to Investigate the Performance of TidalSense Diagnostic Algorithms to Id NCT06788613	Chiesi UK	—
Not Yet Recruiting	Effects of Manual Positive End Expiratory Pressure and Non-invasive Continuous Positive Air Pressure in COPD P NCT07079527	Riphah International University	N/A
Recruiting	Effect of Rehabilitation at Moderate Altitude on Airway Resistance Measured With Forced Oscillation Technique NCT07063563	Eastern Switzerland University of Applied Sciences	N/A
Active Not Recruiting	Oxygen Therapy During Exercise Training in Inpatient Rehabilitation in Chronic Lung Disease- Does it Matter? NCT07044843	Eastern Switzerland University of Applied Sciences	N/A
Completed	Safety and Efficacy of JKN2304 Inhalation Solution in Patients With Moderate to Severe COPD NCT07450482	Joincare Pharmaceutical Group Industry Co., Ltd	Phase 2
Recruiting	Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3 NCT06891755	Apreo Health, Inc.	N/A
Not Yet Recruiting	Value of Volume Oxygenation Index to Detect Early Failure of Non-invasive Ventilation in Acute Exacerbation of NCT07074210	Assiut University	—
Recruiting	Biannual Review of Exhaled Air and Trends in Health Evaluation in COPD NCT07045948	Universitair Ziekenhuis Brussel	N/A
Recruiting	Clinical Study on the Treatment of Stable Bronchiectasis With Bailing Capsules Combined With Guben Kechuan Gra NCT07114120	Second Affiliated Hospital, School of Medicine, Zhejiang University	Phase 4
Recruiting	Effects of Benson's Relaxation and Tai Chi in COPD NCT07076667	Riphah International University	N/A
Not Yet Recruiting	The AcCREDiT 2 Study NCT07029672	Manchester University NHS Foundation Trust	—
Not Yet Recruiting	Effects of CreaSafe® on Kidney, Muscle, and Cardiopulmonary Function in Athletes and COPD Patients NCT06991426	Federal University of São Paulo	Phase 4
Not Yet Recruiting	Evaluating the EAPOC-COPD System NCT06852339	Women's College Hospital	N/A
Recruiting	Doxapram Administration on Diaphragmatic Excursion in Mechanically Ventilated Patients With Chronic Obstructiv NCT07022704	Cairo University	—
Not Yet Recruiting	Efficacy Of Inpatient Pulmonary Rehabilitation Program In Elderly Patients With Acute Exacerbation Of COPD NCT07020182	Al-Azhar University	N/A
Completed	Assessing Optimal Inhaler Strategies During Acute Exacerbations of COPD (AECOPDs) Using Oscillometry NCT06495047	McGill University Health Centre/Research Institute of the McGill University Health Centre	—
Recruiting	SWEEP: Shuttle Walking Test for Exercise Evaluation in Pulmonary Resection NCT07102589	Seoul National University Bundang Hospital	—
Not Yet Recruiting	Supporting Patients Starting New Medicines: Evaluating the myCare Start Service in Switzerland NCT07036471	University of Geneva, Switzerland	N/A
Recruiting	APP-based Medical Device for Education and Training of Inhalation Technique NCT07145632	Karolinska Institutet	N/A
Recruiting	Validation and Clinical Utility of the Lung Sliding Index (LSI) for Differentiating Pulmonary Diseases NCT06983366	Assiut University	—
Recruiting	Clinimetric Properties of Muscle Mass and Stiffness Measurements of the Quadriceps in Patients With COPD NCT06994689	Groupe Hospitalier du Havre	—
Recruiting	Combined Effects of Transcutaneous Electrical Diaphragmatic Stimulation With ACBT'S in Copd NCT07079553	Riphah International University	N/A
Recruiting	The Effects of Oscillatory Positive Expiratory Pressure (OPEP) Therapy in Patients With COPD NCT06614959	McGill University Health Centre/Research Institute of the McGill University Health Centre	N/A
Recruiting	Predicting Acute Exacerbations of COPD Using Wearable Devices and Remote Monitoring Technology With AI/ML Mode NCT06802003	McGill University Health Centre/Research Institute of the McGill University Health Centre	—
Not Yet Recruiting	Evaluation of the Effectiveness of The Volara System Determined by Sputum Movement and Production NCT06937216	Baxter Healthcare Corporation	N/A
Not Yet Recruiting	Respiratory Oxygen Adherence Monitor for Chronic Obstructive Pulmonary Disease Patients NCT06874101	Barron Associates, Inc.	N/A
Not Yet Recruiting	ABCDEF Bundle to Prevent Delirium for COPD Patients NCT06974318	Istanbul Saglik Bilimleri University	N/A
Not Yet Recruiting	Comparing BTVA and MWA in COPD With Early Lung Cancer: Efficacy and Safety NCT06929390	Henan Provincial People's Hospital	N/A
Enrolling By Invitation	Near-Infrared Spectroscopy Measurements in Chronic Obstructive Pulmonary Disease NCT06976762	Tokat Gaziosmanpasa University	—
Not Yet Recruiting	Change in Task-related Oxygen Uptake After EBV Treatment NCT06702072	Dirk-Jan Slebos	—
Recruiting	The Use of Entropy to Assess Sleep Disordered Breathing in Chronic Respiratory Disease NCT07060079	University College, London	—
Recruiting	Brain and Peripheral Muscle Oxygenation in Patients With Chronic Obstructive Pulmonary Disease NCT07285642	Saglik Bilimleri Universitesi	N/A
Not Yet Recruiting	Perioperative Risk Factors Related to the Prognosis of Lung Transplantation: A Retrospective Study NCT06922916	Zhejiang University	—
Not Yet Recruiting	A Study Comparing Doxycycline and Levofloxacin for Treating COPD Exacerbations NCT06915688	Amina Aslam	N/A
Not Yet Recruiting	Development of the Drug and Alcohol Respiratory Health Test NCT06921278	King's College London	—
Completed	The Effect of Transcranial Direct Current Stimulation (tDCS) on Dyspnoea Perception, Pulmonary Function and Fu NCT06944626	Okan University	N/A
Recruiting	Symptoms and Functions in Patients With COPD and Chronic Bronchitis Switching From CIG to THS NCT07108166	Philip Morris Products S.A.	N/A
Completed	Comparative Effects of Triple Inhaled Therapy With Budesonide/Glycopyrronium/Formoterol Versus Fluticasone Fur NCT06905483	Thammasat University	Phase 4
Not Yet Recruiting	Air Pollution and Inhaled Corticosteroids in COPD NCT06552364	University of British Columbia	Phase 4
Not Yet Recruiting	Pulmonary Deposition of Ultrasound Rock Salt Aerosol Inhalation Therapy NCT06891274	Jingen Xia	N/A
Not Yet Recruiting	Efficacy of Osteopathic Manipulative Techniques in Patients With Chronic Obstructive Pulmonary Disease NCT06865703	Beni-Suef University	N/A
Not Yet Recruiting	In This Study, the Sponsor Would Like to Collaborate with Institution and Investigator to Aggregate Participan NCT06798688	Respiree Pte Ltd	—
Completed	Dyspnea and Psychosocial Effects of Hand Fan Application in COPD Patients NCT06857422	Ardahan University	N/A
Recruiting	Reducing Breathlessness With Dronabinol in COPD Patients NCT06473701	Vejle Hospital	Phase 3
Recruiting	"The Effect of Inhaled Nitroglycerin for COPD Patients NCT06785337	Beni-Suef University	Phase 2 / Phase 3
Active Not Recruiting	Progressive Relaxation for COPD: Effects on Insomnia and Satisfaction NCT06933602	Ceylan Aksoy	N/A
Recruiting	Supported Rescue Packs Post-discharge in Chronic Obstructive Pulmonary Disease NCT06347536	Guy's and St Thomas' NHS Foundation Trust	Phase 3
Recruiting	Community Exercise Treating Effect on Cardiopulmonary Disease Patients NCT07154355	Guangdong Provincial People's Hospital	N/A
Active Not Recruiting	The Effectiveness of Two Distinct Ventilation Strategies Escalating Positive End Expiratory Pressure (PEEP) an NCT06847412	Ain Shams University	N/A
Completed	Phase 1/Phase 2a Study of AERO-007 Inhalation Solution, a Nebulized LABA/LAMA Combination for Maintenance Trea NCT06841640	AeroRx Therapeutics Inc.	Phase 1 / Phase 2
Recruiting	My Lung Health Coach-A Virtual COPD Self-management Support Program Integrated Into the Electronic Patient Rec NCT07027852	Women's College Hospital	N/A
Recruiting	The REDUCE EU Study - Endobronchial Thermal Liquid Ablation (ETLA) for the Treatment of Emphysema NCT06655428	Morair Medtech, LLC	N/A
Recruiting	Leveraging Lung Cancer Screening to Optimize Screening Outcomes and COPD Management: COPD in LCS Registry NCT06974981	Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University	—
Completed	Comparative Effects of Wim Hoff Method and Box Breathing Method in Mild COPD NCT07506317	Riphah International University	N/A
Withdrawn	A Mobile Integrated Health Intervention to Manage Congestive Health Failure and Chronic Obstructive Pulmonary NCT05540158	University of Massachusetts, Worcester	—
Not Yet Recruiting	Detection of Early Airway Obstruction in Patients With COPD Using RCexp NCT06456047	East Slovak Institute for Cardiovascular Diseases	—
Not Yet Recruiting	Study of Sleep Quality in the Intensive Care Unit and Association with Weaning from Invasive Ventilation in Pa NCT06653933	University Hospital, Grenoble	—
Recruiting	Investigation of the Respiratory Profile of Patients With Obstructive Pulmonary Disease (ASTHMA, COPD) NCT06966271	Tradeflex Ltd	—
Recruiting	Respiratory Syncytial Virus Infection in Exacerbations of Chronic Obstructive Pulmonary Diasease: the RECODE S NCT06735612	Fundacio Privada Mon Clinic Barcelona	—
Recruiting	Physiologic Effects of Nasal High Flow on Exercise Tolerance in COPD NCT06578156	University of Miami	N/A
Recruiting	Effectiveness of a Physical ACtivity Coaching Intervention Using E-Health for COPD Patients in Pulmonary Rehab NCT06732869	Instituto Politécnico de Leiria	N/A
Not Yet Recruiting	A Study to Investigate Using Inhaled Fexlamose to Treat Adult Participants Who Have Moderate to Severe COPD NCT06731959	Aer Therapeutics	Phase 2
Completed	Effects of Manual Diaphragmatic Technique Versus Lateral Coastal Breathing Exercises Among COPD Patients. NCT06844994	Riphah International University	N/A
Recruiting	Management of COPD Patients With BoraCare® Remote Monitoring Solution Including BVS3 Early Detection Score for NCT06523140	Biosency	N/A
Recruiting	AYLo - AutoimmunitY and Loss of y NCT06696027	University of Bonn	—
Active Not Recruiting	Boosting Regional Integration for COP D Care Through Guided Implementation and Audit of Post Exacerbation Tran NCT06646419	AstraZeneca	—
Recruiting	Bronchodilators and Lung Mechanics During Exercise in COPD NCT06825013	Dr. J. Alberto Neder	Phase 4
Recruiting	Impact of Remote Vital Signs Monitoring in People Using Long-term Oxygen Therapy NCT06882265	University of Sao Paulo General Hospital	N/A
Not Yet Recruiting	Spirometry ,diaphragmatic Ultrasound and Skeletal Muscle Mass in Patients with Chronic Obstructive Pulmonary D NCT06634485	Assiut University	—
Completed	The COPD Optimiser NCT06659666	General Practitioners Research Institute	—
Completed	Effects of Core Stabilization and Inspiratory Muscle Training in Patients With COPD NCT06510686	Mustafa Ertuğrul Yaşa	N/A
Recruiting	The Efficacy of Fluticasone Furoate/Vilanterol/Umeclidinium Compared With Vilanterol/Umeclidinium in Reducing NCT06474039	Mahidol University	Phase 3
Enrolling By Invitation	The Italian Registry of Patients with Chronic Obstructive Pulmonary Disease NCT06652776	University of Milan	—
Recruiting	Supporting Evidence-based Responses to Emotional Needs in Emphysema NCT06600126	University of Pennsylvania	N/A
Recruiting	Assessment the Effectiveness of BTVA in COPD and Ablation in Pulmonary Nodules by Pulmonary MRI NCT07045532	Shanghai Chest Hospital	—
Not Yet Recruiting	Minimal Clinically Significant Difference (MCID) of Multidimensional Dyspnea Profile (MDP) in COPD Patients Un NCT06012006	Assistance Publique - Hôpitaux de Paris	N/A
Completed	Effect of Home-Based Pulmonary Rehabilitation NCT06954948	Hawler Medical University	N/A
Completed	Feedback on the New Profession of Care Manager in Maintenance Pulmonary Rehabilitation Programmes NCT06448559	GCS CIPS	—
Recruiting	The Effect of Motivational Interviewing-Based Education on Treatment Adherence and Self-Care Agency in COPD Pa NCT06733662	Kahramanmaraş İstiklal University	N/A
Not Yet Recruiting	Effects of Breathing Exercises With and Without Inspiratory Muscle Training in COPD Patients NCT06555445	Riphah International University	N/A
Recruiting	A Study to Evaluate Solrikitug in Participants With COPD (ZION) NCT06496620	Uniquity One (UNI)	Phase 2
Recruiting	The Effects of Different Vibration Exercises on COPD Patients NCT06413524	Taipei Medical University	N/A
Recruiting	Cardiopulmonary Adaptations to High-intensity Interval Training (HIIT) in COPD NCT06551441	Rigshospitalet, Denmark	N/A
Recruiting	Effect of Breather in COPD Patients With Intermittent Claudication NCT06529185	Cairo University	N/A
Recruiting	Acoustic Waveform Respiratory Evaluation NCT06512064	Indiana University	N/A
Recruiting	Sleepiz One+ vs. Capnography and Electrocardiography NCT06569940	Sleepiz AG	N/A
Recruiting	Early Diagnosis and Treatment of Undiagnosed Asthma or COPD: THE UCAP 2 TRIAL NCT06392776	Ottawa Hospital Research Institute	N/A
Completed	A Controlled Breathing Intervention to Reduce Stress and Improve Symptoms in COPD Patients (REST) NCT06404008	University of Texas at Austin	N/A
Completed	Pulmonary Diffusing Capacity During Incremental Exercise in COPD NCT06505902	Rigshospitalet, Denmark	N/A
Recruiting	Effect of Elastic Chest Compression on Functional Exercise Capacity and Respiratory Performance in Patients Wi NCT06519474	National Taiwan University Hospital	N/A
Recruiting	The Clear Conversations Project NCT06508840	University of Sheffield	—
Completed	Best End-Expiratory and Driving-pressure for Individualized Flow Controlled Ventilation in Patients With COPD NCT05812365	Universitätsklinikum Hamburg-Eppendorf	—
Recruiting	Respiratory Strategies in COPD Patients With Persistent Hypercapnia Following Exacerbation NCT07065799	IRCCS Azienda Ospedaliero-Universitaria di Bologna	N/A
Recruiting	Identification of Multiple Pulmonary Diseases Using Volatile Organic Compounds Biomarkers in Human Exhaled Bre NCT06528418	ChromX Health	—
Completed	The Effect of Telenursing Interventions in Empowering Patients With COPD NCT06217718	Zahide Aksoy	N/A
Recruiting	Improving Pharmacological Transition of Palliative Care Patients From Inpatient to Outpatient Care NCT06648733	University Hospital Muenster	N/A
Recruiting	Health Literacy, Physical and Cognitive Function, Health-related Behaviors, and Quality of Life in COPD NCT06497816	Hacettepe University	—
Completed	The Effect of Stress Ball on COPD Patients Receiving Noninvasive Mechanical Ventilation Support NCT06461169	Kafkas University	N/A
Completed	Effect of Ensifentrine Treatment on CAT Score NCT06460493	Verona Pharma plc	Phase 3
Unknown	Effect on Bronchodilation Response and Ventilation Heterogeneity of Different Inhalation Volumes in COPD NCT05381415	University of Milan	—
Recruiting	A Translational Study for Prediction of Biomarkers and Identification of Phenotype and Endotype of COPD and Ea NCT06724848	AstraZeneca	—
Recruiting	Prevalence of Sarcopenic Obesity in COPD NCT06822504	IRCCS San Raffaele Roma	—
Recruiting	Motivational Enhancement Therapy's Impact on d COPD Outcomes in Geriatric Patient NCT06421896	Alexandria University	N/A
Recruiting	Predictive Properties of the 6-Minute Stepper Test for Mortality in COPD NCT06703359	ADIR Association	—
Completed	Effect of Pulmonary Telerehabilitation and Telemonitoring for Patients With Chronic Respiratory Diseases NCT05824910	University of Manitoba	N/A
Completed	Using Large Language Models Such As GPT-4 to Assess Guideline Adherence in Patients With Chronic Obstructive P NCT06410547	Charite University, Berlin, Germany	N/A
Completed	Mechanical Muscle Proprieties in Patient with COPD NCT06410950	Spitalul Clinic de Boli Infecțioase și Pneumoftiziologie Dr. Victor Babeș Timișoara	—
Completed	Psychological Distress in Patients With COPD NCT06395311	Spitalul Clinic de Boli Infecțioase și Pneumoftiziologie Dr. Victor Babeș Timișoara	—
Recruiting	Trial Evaluating the Rate of Pneumothorax in Severe Emphysema Secondary to Endoscopic Volume Reduction With Tw NCT06181357	University Hospital, Limoges	N/A
Completed	Technology Assisted Nudging to Increase Physical Activity Among Hospitalised Medical Patients NCT06336252	Bispebjerg Hospital	N/A
Recruiting	The Clinical Characteristics, Treatment and Prognosis of Tuberculosis-associated COPD NCT06074042	Peking University Third Hospital	—
Recruiting	Cervical Nags Effect on Accessory Muscles NCT06736145	Riphah International University	N/A
Active Not Recruiting	SADT in COPD and Oscillometry in Obstructive Airway Disease in Primary Care. The SCOOP-study NCT07374172	General Practitioners Research Institute	—
Recruiting	Refractory Breathlessness in COPD NCT07160322	Seoul National University	—
Recruiting	Integrated Approach in Frail Older People with Atrial Fibrillation NCT06775028	Heart Care Foundation	N/A
Recruiting	The Effects of Positive Airway Pressure on the Mucolytic Effects of NAC (TEAM) NCT06152653	University of California, San Francisco	Phase 4
Unknown	Airvo 3 Respiratory Rate Validation Study NCT06329609	Fisher and Paykel Healthcare	N/A
Unknown	Treatment of Acute Hypercapnic Respiratory Failure With OptiflowTM or Optiflow+DuetTM Nasal Cannula in COPD-pa NCT06257667	Aalborg University Hospital	N/A
Recruiting	Effectiveness of Motivational Interviewing in Patients With COPD NCT06783582	Zeynep Yildirim	N/A
Recruiting	Multiparametric Home Telemonitoring of Patients With Chronic Obstructive Pulmonary Disease Exacerbation NCT06331416	University of Trieste	N/A
Completed	Anti-Platelets in Chronic Obstructive Pulmonary Disease NCT05567562	Brigham and Women's Hospital	Phase 2
Recruiting	Zephyr Valve Japan Post-Marketing Surveillance NCT06332885	Pulmonx Corporation	—
Terminated	Evaluation of the Impact of Therapeutic Education Workshops for COPD Patients in the North-West Val d'Oise Are NCT06298487	Hôpital NOVO	N/A
Unknown	Oral Supplementation During PR Participation in COPD NCT06324214	McGill University Health Centre/Research Institute of the McGill University Health Centre	Phase 2
Recruiting	Validation of a Digital Platform for Functional Respiratory Rehabilitation NCT06252818	Bio-Sensing Solutions S.L. (DyCare)	N/A
Completed	Impulse Oscillometry in COPD Exacerbation NCT07185581	Deniz Bilici	—
Completed	Effects of Oral Doxofylline and Procaterol on Chronic Obstructive Pulmonary Disease NCT06346691	Thammasat University	Phase 4
Unknown	QualiTy of Life Evaluation in Patients With ChRonic ObstructIve Pulmonary Disease Who Require Tiotropium as ad NCT06170125	Elpen Pharmaceutical Co. Inc.	—
Completed	Live Vaccines and Innate Immune Training in COPD. NCT06257212	Josefin Eklöf	Phase 4
Recruiting	Study of Inflammatory and Physiological Profiles of Healthy and Diseased Lung NCT06144476	Guy's and St Thomas' NHS Foundation Trust	—
Completed	Maximal Oxygen Uptake (VO2max) in Patients With COPD NCT06257381	Rigshospitalet, Denmark	—
Completed	Validation of Urdu Version of Leicester Cough Questionnaire (LCQ) NCT06674395	Riphah International University	—
Recruiting	PEP-buddy in COPD: Effect on Dyspnea Severity and Mechanism of Action NCT05938738	University Medical Center Groningen	N/A
Recruiting	Respiratory Muscle Fatigue and Lower Extremity Muscle Oxygenation NCT06217276	Istanbul Medipol University Hospital	N/A
Recruiting	Mechanical Properties of Peripheral and Accessory Respiratory Muscles in Chronic Obstructive Pulmonary Disease NCT06201403	Istanbul Medipol University Hospital	—
Recruiting	Chair-based and Standard Exercise Programs in People With COPD NCT06201299	Istanbul Medipol University Hospital	N/A
Withdrawn	IKANOS: Breztri Maintenance Versus Any Non-Triple Inhaled Therapy After Hospitalization for a COPD Exacerbatio NCT05970263	AstraZeneca	Phase 4
Unknown	Evaluation of VQm PHM on Pulmonary Health Parameters for ICU NCT06147674	Rostrum Medical Innovations Inc.	—
Completed	The Effect of Prayer on Dyspnea Severity, Anxiety and Spiritual Well-Being in Individuals With COPD NCT05997394	Cumhuriyet University	N/A
Recruiting	The Effect of a Technology-Mediated Integrated Walking and Tai Chi Intervention on Physical Function in Vetera NCT05701982	VA Office of Research and Development	N/A
Unknown	Functional Status in COPD Patients After Exercise Rehabilitation Program NCT06142266	Assiut University	N/A
Terminated	Heat Waves and the Elderly With COPD NCT06295523	University of Texas Southwestern Medical Center	N/A
Completed	Effect of Web-Based Adaptation and Insomnia Severity in Individuals Using Noninvasive Ventilators at Home NCT06343324	KTO Karatay University	N/A
Recruiting	Effectiveness of Physical Exercise of Patients With Chronic Non-communicable Disease NCT06476015	Fundacion Universitaria Maria Cano	—
Completed	Viscoelastic Properties of Respiratory and Peripheral Muscles of COPD Patients NCT06580353	Gaziantep Islam Science and Technology University	—
Unknown	Screening for Lung Health by a Mobile Device NCT06232356	SEPAR- EPOC	—
Completed	Balance, Walking Speed, Quadriceps Femoris Muscle Strength and Quality of Life in Falling and Non-falling Indi NCT06099002	Kırıkkale University	—
Active Not Recruiting	Impairments That Affect Correct Inhaler Use in COPD NCT06135324	COPD Foundation	—
Recruiting	Effects of Eccentric Exercise Training in Patients With COPD NCT06168266	Fu Jen Catholic University	N/A
Recruiting	Heterogeneity of Lung Ventilation Determined by EIT During PFT in Patients With PRISM NCT06199258	Sir Run Run Shaw Hospital	—
Unknown	Effectiveness of Harmonica Playing in Improving Lung Function Among COPD Patients NCT05995847	The First Affiliated Hospital of Guangzhou Medical University	N/A
Unknown	Biomarkers of Dementia in Chronic Sleep and Breathing Disorders NCT06377332	Woolcock Institute of Medical Research	—
Not Yet Recruiting	Permian Health Women's Lung Health Study NCT06029543	Permian Health Lung Institute	—
Unknown	Ultrasonographic Evaluation of Diaphragm and Quadriceps in Chronic Obstructive Pulmonary Disease (COPD) Patien NCT04509128	IRCCS San Raffaele Roma	—
Completed	Femoral Artery Blood Flow During Rest and One-leg Knee Extensor Exercise in Patients With COPD NCT06135701	Rigshospitalet, Denmark	N/A
Completed	RCT of Vapendavir in Patients With COPD and Human Rhinovirus/Enterovirus Upper Respiratory Infection NCT06149494	Altesa Biosciences, Inc.	Phase 2
Unknown	Health Coaching Telemedicine Program for Lung Transplant Candidates With End-stage Lung Disease. NCT06428513	Sheba Medical Center	N/A
Suspended	Zofin to Treat Chronic Obstructive Pulmonary Disease (COPD) NCT05643729	ZEO ScientifiX, Inc.	Phase 1 / Phase 2
Recruiting	Supramaximal High-Intensity Interval Training in People With and Without Chronic Obstructive Pulmonary Disease NCT06068322	Umeå University	N/A
Recruiting	Pulmonary Hypertension SOLAR NCT04778046	Bastiaan Driehuys	Phase 2
Recruiting	The Effect of Education and Reminder Messages on the Fatigue Level of Individuals With COPD NCT06286072	Kirsehir Ahi Evran Universitesi	N/A
Recruiting	Long-term Home-based Exercise for Patients With COPD: the COPDtoParis Project NCT06235502	Aalborg University Hospital	N/A
Unknown	Palliative Care Health Literacy Education and QOL Compared to Usual Care NCT06089499	University of Missouri, Kansas City	N/A
Completed	Clinical Trial to Assess Effect of Verapamil on Systemic Exposure of EP395 and Effect of EP395 on Systemic Exp NCT06118684	EpiEndo Pharmaceuticals	Phase 1
Terminated	Functional and Structural Assessment of Endobronchial Valve Recipients Using Dynamic Hyperpolarized Xenon-129 NCT05433961	Xemed LLC	Phase 1
Active Not Recruiting	Aiding COPD and CHF Ultrasound-guided Management Through ENhanced Point Of Care UltraSound NCT05423652	Michelle Grinman	N/A
Enrolling By Invitation	K-HEALTH in AIR - Barcelona Pilot - Cohort NCT06421402	Institut d'Investigacions Biomèdiques August Pi i Sunyer	—
Completed	The Effectiveness of Dual-task Exercises in Individuals With COPD NCT05930158	Marmara University	N/A
Terminated	Integrating ePReBMs From Phoenix in Respiratory Diseases NCT05827302	University of Alberta	N/A
Unknown	Expiratory Flow Accelerator (Efa) vs Efa + High Flow in Chronic COPD and Bronchiectasis NCT06017739	Azienda Socio Sanitaria Territoriale della Valle Olona	N/A
Unknown	Clopidogrel for the Prevention of Exacerbations in Severe COPD NCT06021990	Lady Reading Hospital, Pakistan	Phase 3
Completed	A Study to Evaluate Safety and Efficacy of BOTOX in Adults With Moderate COPD NCT06003049	RMW Testing	Phase 2
Completed	Clinical Variables and Dyspnea and Fear of Movement in Chronic Obstructive Pulmonary Patients NCT06442059	Kırıkkale University	—
Unknown	Anxiety Management in Breathlessness. NCT06066658	University of Leicester	N/A
Recruiting	Impact of Long-acting Bronchodilator- -Corticoid Inhaled Therapy on Ventilation, Lung Function and Breathlessn NCT06110403	University Hospital, Lille	Phase 1 / Phase 2
Unknown	Comparison of Ipratropium / Levosalbutamol Fixed Dose Combination and Ipratropium and Levosalbutamol Free Dose NCT06040424	Neutec Ar-Ge San ve Tic A.Ş	Phase 3
Active Not Recruiting	COPD Case Finding In Nottingham and District: C-FIND COPD A Pilot Study NCT06008145	Nottingham University Hospitals NHS Trust	—
Completed	Real-World Treatment Patterns and Patient Reported Outcome in COPD (REMIND) NCT05903989	AstraZeneca	—
Recruiting	Exploring Novel Biomarkers for Emphysema Detection NCT05825261	Maastricht University	—
Recruiting	A Multicenter, Prospective Cohort Study of Preserved Ratio Impaired Spirometry(PRISm) in a Population NCT06340295	Peking University First Hospital	—
Completed	Respiratory Proprioceptive Neuromuscular Facilitation Technique in Chronic Pulmonary Obstructive Disease Patie NCT05876403	Riphah International University	N/A
Unknown	Novel Predictors of Premature Aging in COPD Patients NCT06019286	Assiut University	—
Withdrawn	The UCAP 2 Pilot Study NCT06014840	Ottawa Hospital Research Institute	N/A
Recruiting	Telehealth and Onsite Maintenance Exercise in Chronic Lung Disease NCT06304207	MGH Institute of Health Professions	N/A
Unknown	Comparison of Ipratropium / Levosalbutamol Fixed Dose Combination and Ipratropium and Levosalbutamol Free Dose NCT05890638	Neutec Ar-Ge San ve Tic A.Ş	Phase 3
Recruiting	Right Ventricular Response to Exercise Among Patients With Chronic Obstructive Pulmonary Disease NCT05896579	University of Colorado, Denver	N/A
Unknown	Effects of Blow Bottle Verses ACBTs Technique in Patients of Chronic Obstructive Pulmonary Disease NCT06189196	Riphah International University	N/A
Recruiting	Passive Heat Therapy for People With COPD NCT05962164	University of British Columbia	N/A
Completed	Measuring Lung Mechanics in Patients with COPD Using the REOM Handheld Portable Device NCT05913323	McGill University Health Centre/Research Institute of the McGill University Health Centre	—
Completed	Lung Hyperinflation and Response to Pulmonary Vasodilator Therapy NCT06613321	Central Hospital, Nancy, France	—
Unknown	Impact of Fixed TRIple Therapy With Beclometasone/Formoterol/Glycopyrronium DPI (Trimbow® in NEXThaler Device) NCT05948891	Chiesi SAS	—
Unknown	Usefulness and Efficacy of Telemonitoring of Patients With COPD NCT06135025	University of Monastir	N/A
Completed	Diagnosing Obstructive Lung Disease With Point of Care Ultrasound NCT06251271	Soroka University Medical Center	—
Active Not Recruiting	Pragmatic Assessment of the NuvoAir Clinical Service in the Management of Patients With Chronic Obstructive Pu NCT05955482	NuvoAir Medical PC	—
Completed	Comparison of Jacobson Relaxation Technique and Pranayama Technique in Patients With COPD NCT06463288	Riphah International University	N/A
Recruiting	DUET Versus Standard Interface for Hypercapnic COPD Patients NCT05829083	Larissa University Hospital	N/A
Completed	Comparison of Anterior Chest Compression Assist and Abdominal Thrust Assist Technique COPD NCT05936801	Riphah International University	N/A
Enrolling By Invitation	Goal Concordant Care Learning Laboratory NCT05879211	Duke University	N/A
Recruiting	Evaluation of Safety and Effectiveness of TLD Radiofrequency Ablation in the Treatment of COPD NCT05799664	Hangzhou Broncus Medical Co., Ltd.	N/A
Unknown	A Clinical Validation Study to Evaluate the Diagnostic Accuracy of a Cough-based Auxiliary Diagnosis Algorithm NCT06082791	Ruijin Hospital	—
Recruiting	Diaphragmatic Function as a Biomarker NCT05903001	RWTH Aachen University	—
Completed	Azithromycin and Oesophageal Function in Respiratory Disease NCT05469555	Hull University Teaching Hospitals NHS Trust	—
Unknown	The Living With a Long-Term Condition Study NCT06072287	King's College London	—
Completed	Evaluation by Electrical Impedancemetry of the Variation in Lung Volumes Under Non-invasive Ventilation (NIV) NCT05953298	University Hospital, Bordeaux	N/A
Withdrawn	Thoracic Kyphosis and Osteoporosis: Study of Their Relationship With Respiratory Functions in Chronic Obstruct NCT04757714	Centre Hospitalier Régional d'Orléans	N/A
Completed	Effectiveness of IMT/PEP Therapy in Group E COPD and Comparison of GOLD vs STAR Classifications NCT07001462	Bugra Kerget	—
Completed	Efficacy of CPAP Therapy on Pulmonary Function Test in Patients With COPD-OSA Overlap Syndrome NCT05857475	Mahidol University	N/A
Recruiting	Evaluation of 3D Magnetic Resonance Spirometry: Comparison with Spirometry in Healthy Subjects and Patients wi NCT05724745	Commissariat A L'energie Atomique	N/A
Unknown	Single and Multiple Ascending Dose Study of AER-01 NCT05862623	Aer Therapeutics	Phase 1
Completed	Comparative Effects of IMT Vs EMT Along With AIT in COPD Patients NCT06308302	Riphah International University	N/A
Unknown	Assessment of Oral and Nasal Breathing With Sensors Analyzing Algorithm NCT05869071	Oulu University Hospital	—
Completed	REMAP-WEST-FLARE - FLAg for Review Efficacy Investigation NCT05745155	Senti Tech Ltd	N/A
Completed	Phase 1 Study Into Pharmacokinetics and Food Effect of Vapendavir in Healthy Participants and Participants Wit NCT05962645	Altesa Biosciences, Inc.	Phase 1
Unknown	Comparative Effects of BBT and Active Cycle of Breathing Technique on Dyspnea and Quality of Life in COPD NCT05947253	Riphah International University	N/A
Completed	Balance Training in Chronic Obstructive Pulmonary Disease NCT05972239	Istituti Clinici Scientifici Maugeri SpA	N/A
Unknown	Clinical Study for the Effectiveness of Roflumilast Treatment in COPD Greek Patients Based on Standard Clinica NCT05426915	Elpen Pharmaceutical Co. Inc.	—
Active Not Recruiting	Quebec Lung Cancer Screening PLUS Trial NCT05444062	Nicole Ezer, MD, FRCPC, MPH	N/A
Completed	Pulmonary Rehabilitation Through Tele Rehabilitation for COPD in Pakistan NCT05828602	Riphah International University	N/A
Completed	Progressive Muscle Relaxation and Deep Breathing Exercises NCT05846204	Ataturk University	N/A
Unknown	DYNAMIC AI: Digital Innovation With Remote Management and Predictive Modelling to Integrate COPD Care With Art NCT05914220	NHS Greater Glasgow and Clyde	—
Unknown	Immunological Basis for Mepolizumab Activity in COPD NCT05320939	Temple University	Phase 2
Active Not Recruiting	The Effect of Face Hand Fan Application on Dyspnea NCT06265831	Bartın Unıversity	N/A
Completed	NEXThaleR Real-world Study Assessing the EffectivenesS of BDP/FF/G Fixed triPle cOmbiNation on Symptom scorEs NCT05743608	Chiesi Hungary Ltd.	—
Recruiting	Sonographic Diaphragm Function in AECOPD NCT05671198	Isala	—
Completed	Interest of Performing Two 6-minute Walk Tests at the End of a Pulmonary Rehabilitation Program, in COPD Patie NCT05850299	University Hospital, Brest	—
Recruiting	COPD at a Street Level NCT05660460	Hvidovre University Hospital	N/A
Completed	Respiratory Exercise to Copd With Virtual Reality Glasses on Dyspnea, Anxiety and Qualıty of Life NCT06021106	Ardahan University	N/A
Terminated	Treatment Efficacy of Systemic Corticosteroids in AECOPD Patients With Higher Blood Eosinophil Levels NCT05059873	Capital Medical University	Phase 4
Completed	Association Between Handgrip Strength and Small Airway Disease in Patients with Stable Chronic Obstructive Pul NCT06223139	Thammasat University	—
Completed	Pulmonary Ventilation Function Between Patients With Primary and Recurrent Incisional Hernia: a Cross-sectiona NCT05991024	Fudan University	—
Unknown	Impact of COVID-19 on Lung Function in COPD Patients. NCT05770440	Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina	—
Recruiting	Evaluate the Effect of Dietary Supplement Combined Exercise Among Patients With Sarcopenia Comorbid With Lung NCT05926713	Orient Europharma Co., Ltd.	N/A
Unknown	Dexmeditomedine Versus No Sedation in Management of Agitation in COPD Patients Receiving Noninvasive Ventilati NCT05774145	Assiut University	—
Unknown	Effects of BFR Interventions in Healthy Individuals and Individuals With COPD NCT05734534	Morten Hostrup, PhD	N/A
Completed	Sleepiz One+ Versus Capnography and Electrocardiography NCT05712226	Sleepiz AG	N/A
Unknown	Short Acting Agents Vs Long Acting in Frequent Excerbator COPD Patients NCT05748977	Assiut University	EARLY_Phase 1
Recruiting	Thermotherapy Against Persistent Bacterial LUNG Infections NCT05351242	Chronic Obstructive Pulmonary Disease Trial Network, Denmark	N/A
Enrolling By Invitation	Breath Analysis and Arterial Stiffness in Patients With Respiratory Diseases NCT05727852	I.M. Sechenov First Moscow State Medical University	—

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