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Not Yet RecruitingNCT07208123

Mechanistic Studies of Chronic COPD Using Single-Cell Sequencing and Single-Cell Spatial Transcriptomics

A Bidirectional Cohort Study of Single-Cell Sequencing and Single-Cell Spatial Transcriptomics in Chronic COPD

Status
Not Yet Recruiting
Phase
Study type
Observational
Enrollment
150 (estimated)
Sponsor
Tongji University · Academic / Other
Sex
All
Age
Healthy volunteers

Summary

This study is an ambispective cohort study, the sample from patients were from both previously stored and freshly collected . The objective of this study is to investigate the molecular pathological changes underlying the development of chronic obstructive pulmonary disease (COPD). We will use single cell sequencing technology to analyze lung tissue samples from patients who underwent lung resection, with lung tissue from patients without COPD serving as controls. This research aims to provide insights into the pathogenesis of COPD.

Conditions

Timeline

Start date
2025-09-30
Primary completion
2026-12-31
Completion
2027-12-31
First posted
2025-10-06
Last updated
2025-10-06

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT07208123. Inclusion in this directory is not an endorsement.

Mechanistic Studies of Chronic COPD Using Single-Cell Sequencing and Single-Cell Spatial Transcriptomics (NCT07208123) · Clinical Trials Directory