NCT07369206

ICU Admission Diagnoses and ICU Mortality

Association of Admission Syndromic Diagnoses With ICU Mortality in a Mixed Adult Intensive Care Unit: Retrospective Cohort

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 1,248 (actual)
• Sponsor: Ataturk University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This retrospective cohort study will evaluate whether syndromic clinical diagnoses present at ICU admission are associated with ICU mortality, independent of physiologic severity scores. Adult patients admitted to a tertiary mixed ICU during 2025 will be assessed.

Detailed description

Data will be obtained retrospectively from the hospital information system and ICU clinical records. Variables will be recorded based on the first 24 hours after ICU admission. Demographics, admission characteristics, comorbidities, severity scores (APACHE II, SAPS, SOFA), and admission syndromic diagnoses (e.g., sepsis/septic shock, acute respiratory failure, ARDS, MODS) will be collected. The primary outcome is ICU mortality; secondary outcomes include ICU length of stay and ICU discharge disposition.

Conditions

• Critical Illness
• Sepsis
• Septic Shock
• Acute Respiratory Distress Syndrome (ARDS)
• Acute Respiratory Failure
• Multiple Organ Dysfunction Syndrome

Timeline

• Start date: 2026-01-30
• Primary completion: 2026-02-02
• Completion: 2026-02-02
• First posted: 2026-01-27
• Last updated: 2026-02-04

Locations

1 site across 1 country: Turkey (Türkiye)