| Not Yet Recruiting | Right Ventriculo-Arterial Coupling During Fluid Loading in ICU Patients NCT07537621 | CHU de Reims | — |
| Not Yet Recruiting | Validation of the iCVS Model in Patients Admitted to the Intensive Care Unit NCT07256886 | Meir Medical Center | — |
| Not Yet Recruiting | Critical Care Admission Following Emergency Department's Resuscitation Room Care NCT07411976 | Centre Hospitalier Universitaire de Nīmes | — |
| Not Yet Recruiting | A Proof-of-concept Study of Ultrasound Stimulation of the Neck to Enhance Anti-shock Efficacy NCT07467798 | Tao Liu | N/A |
| Not Yet Recruiting | Correlation Between EIT-based Pulse Wave Method for Pulmonary Perfusion Monitoring and Pulmonary Artery Cathet NCT07385963 | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | — |
| Not Yet Recruiting | Enteral Versus Parenteral Nutrition During Recovery After Shock NCT07411014 | Samsung Medical Center | N/A |
| Recruiting | Characterization of Extracellular Vesicles From the Cord Blood of Extremely Preterm New Borns and Their Correl NCT07273643 | University Hospital, Montpellier | — |
| Not Yet Recruiting | Point-of-Care AI Assistance and Critical Care Outcomes: A Randomized Trial NCT07293078 | MetroWest Artificial Intelligence Research Workgroup | Phase 1 / Phase 2 |
| Not Yet Recruiting | IVC Ultrasound Versus Central Venous Pressure for Early Detection of Hypovolemia in Shock Patients NCT07206732 | Assiut University | — |
| Not Yet Recruiting | Femoral Vein, Internal Jugular Vein and Inferior Vein Cava Collapsibility Indices in Polytrauma Patients by So NCT07264374 | Assiut University | — |
| Enrolling By Invitation | Consistency of Fluid Tolerance Evaluation Methods and Their Correlation With Clinical Outcomes in Patients Wit NCT07373717 | Southeast University, China | — |
| Recruiting | Diagnostic and Prognostic Evaluation of Vasorin During Septic Shock NCT07203833 | Centre Hospitalier Universitaire, Amiens | N/A |
| Recruiting | Fluid Management and Individualized Resuscitation in Sepsis NCT07009665 | University Medical Center Groningen | N/A |
| Recruiting | Augmented Pacing for Shock in the Cardiac Intensive Care Unit NCT06713668 | Vanderbilt University Medical Center | N/A |
| Completed | Brachial-radial Pressure Gradient Phenomenon in Critically Ill Patients Treated With Vasoactive Agents NCT07061457 | Jagiellonian University | — |
| Recruiting | Effectiveness of Midodrine as an Adjuvant to Norepinephrine in Weaning Critically Ill Patients From Vasopresso NCT06930235 | Sohag University | N/A |
| Not Yet Recruiting | Estimating Fluid Requirement in Shocked Traumatic Patients by US on SCV NCT06726668 | Assiut University | — |
| Recruiting | Pulse Study: Peripheral Use of Low-dose Vasopressors for Safety and Efficacy in the Intensive Care Unit NCT06920173 | Kingston Health Sciences Centre | Phase 2 |
| Not Yet Recruiting | Reliability of Respiratory Variability of Maximal Aortic Blood Flow Velocity Obtained by Ultrasonography-doppl NCT06845280 | Ankara University | — |
| Active Not Recruiting | Early Hydrocortisone Versus Regular Treatment in Shock in Extremely Preterm Neonates - an Open Randomized Cont NCT07248761 | Coordinación de Investigación en Salud, Mexico | Phase 4 |
| Recruiting | Renin-guided Hemodynamic Management in Patients With Shock NCT05898126 | Università Vita-Salute San Raffaele | N/A |
| Completed | Validation of the Accuracy of a Novel POCT Dry Blood Gas Analyzer in Acute Care Settings NCT06726473 | Zhujiang Hospital | — |
| Not Yet Recruiting | Venous Excess Ultrasound for Personalized Resuscitation in Septic Shock NCT06696391 | Western University, Canada | Phase 3 |
| Not Yet Recruiting | Cardiometry in Hypotensive and Pumonary Congestion NCT06730087 | Assiut University | — |
| Recruiting | Digital Out-of-hospital Management on Clinical Outcomes in Patients With Early Cardiogenic Shock NCT07085221 | Renmin Hospital of Wuhan University | N/A |
| Not Yet Recruiting | Quantitative Ultrasound Assessment of Abdominal Cavity Space NCT06634732 | Ruijin Hospital | — |
| Recruiting | Assessment of Stroke Volume in Shock Using Echocardiography Versus Bioreactive Impedance NCT07020637 | University of Nevada, Las Vegas | — |
| Recruiting | The Prevalence of the Aortic to Radial Pressure Gradient in States of Shock, Outside the Context of Cardiac Su NCT06460519 | Hospices Civils de Lyon | — |
| Not Yet Recruiting | Polish Nationwide Register of Hospitalized Patients in Cardiac Intensive Care Units NCT06371677 | Medical University of Warsaw | — |
| Completed | US Guidance for Radial Arterial Puncture in Shock NCT07362628 | Ismail Erkan Aydin | N/A |
| Unknown | Cardiovascular Metabolic Remodeling in Shock NCT06285513 | University Hospital, Rouen | — |
| Recruiting | Angiotensin II Stress Test. Renin Kinetics During Treatment of Vasoplegic Shock With Angiotensin II. NCT06539234 | University Medical Centre Maribor | — |
| Not Yet Recruiting | Impact of Starting Dose of Vasopressor on Hemodynamic Response in Shock NCT06481839 | University of Illinois at Chicago | N/A |
| Recruiting | Registry of Patients in Shock Treated With Vasopressin NCT06422975 | Hospital Universitario 12 de Octubre | — |
| Completed | Effectiveness and Safety of Penehyclidine Hydrochloride for Improving Microcirculatory Dysfunction in Critical NCT07519226 | Lihua Wen | N/A |
| Not Yet Recruiting | Echocardiographic and Laboratory Findings in Hemodynamic Monitoring of Shocked Patients NCT06343519 | Assiut University | — |
| Recruiting | Evaluating Fluid Responsiveness in ICU Patients Using VTI and Trendelenburg Positioning NCT06418022 | Lenox Hill Hospital | N/A |
| Recruiting | Umbilical Mesenchymal Stromal Cells as Cellular Immunotherapy for Septic Shock NCT05969275 | Ottawa Hospital Research Institute | Phase 2 |
| Completed | Non-invasive Prediction of Fluid and Noradrenaline Responsiveness Using the Carotid Wave Intensity. NCT06197321 | Catharina Ziekenhuis Eindhoven | — |
| Completed | Impact of Sodium Profiling During Haemodialysis on Haemodynamic Tolerance and Sonographic Extravascular Lung W NCT07529990 | Fayoum University | — |
| Recruiting | ICU Combined Assessment of Cardio-Respiratory Exercise NCT06193980 | University of Manitoba | — |
| Recruiting | Early Initiated Vasopressor Therapy in the Emergency Department NCT05931601 | Odense University Hospital | Phase 3 |
| Recruiting | Hemodynamic Response to Angiotensin-II When Used as the Second Vasopressor Agent for Septic Shock NCT06122987 | Kingman Regional Medical Center | Phase 4 |
| Recruiting | Norepinephrine Weaning Guided by the Hypotension Prediction Index in Vasoplegic Shock After Cardiac Surgery NCT05922982 | Centre Hospitalier Universitaire, Amiens | N/A |
| Unknown | Checklists Resuscitation Emergency Department NCT05649891 | Region Skane | N/A |
| Unknown | Epinephrine to Prevent Postintubation Collapse in Shocked ICU Patients NCT06115473 | Ain Shams University | N/A |
| Recruiting | Diagnostic Performance of the Mitral Annulus Velocity Variation Measured by Tissue Doppler to Evaluate the Flu NCT05888974 | Centre Hospitalier Universitaire de Nīmes | — |
| Unknown | Thigh Muscle Mass and Muscle Wasting in Patients in the Emergency Department NCT05978154 | Korea University Ansan Hospital | — |
| Recruiting | Individualised Blood Pressure Targets Versus Standard Care Among Critically Ill Patients With Shock NCT05850962 | Rakshit Panwar | N/A |
| Completed | Novel Predictors of Post Spinal Hypotension in Cesarean Sections: Evaluating Jugular Vein Collapsibility Index NCT05953129 | Gaziosmanpasa Research and Education Hospital | — |
| Completed | Evaluation of Fluid Resuscitation in Shocked Patients by Electrical Cardiometry in Comparison to Transthoracic NCT06075407 | Al-Azhar University | — |
| Active Not Recruiting | SODium BICarbonate for Metabolic Acidosis in the ICU NCT05697770 | Australian and New Zealand Intensive Care Research Centre | Phase 3 |
| Completed | Second Generation DICART Prototype Validation NCT05847998 | Hospices Civils de Lyon | N/A |
| Recruiting | Effects of Increasing Mean Arterial Pressure on Renal Function in Patients With Shock and With Elevated Centra NCT05655065 | University Hospital, Angers | N/A |
| Active Not Recruiting | Use of Ultrasound in the Initial Management of Patients in Shock in the Nancy Emergency Department NCT06573541 | Central Hospital, Nancy, France | — |
| Unknown | Sepsis Early EvaluatioN Through Rapid Ultrasound and veNous Gas Analysis NCT05787184 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Unknown | PCO2 Gab Marker of Tissue Adequacy of Cardiac Output in Shock State NCT05679778 | Assiut University | — |
| Active Not Recruiting | Concordance Study of Therapeutic Decision-making in Patients With Shock Based on Hemodynamic Monitoring NCT05613647 | University Hospital, Angers | — |
| Recruiting | Central Line Study NCT05534971 | Montefiore Medical Center | Phase 4 |
| Enrolling By Invitation | Advancing Health Information Exchange (HIE) During Inter-hospital Transfer (IHT) to Improve Patient Outcomes NCT05443321 | Brigham and Women's Hospital | N/A |
| Completed | Pragmatic Randomized Trial for Arterial Catheters in the Critical Care Environment NCT05411315 | Dartmouth-Hitchcock Medical Center | N/A |
| Completed | Evaluation of the LVivo Image Quality Scoring (IQS) NCT05563701 | DiA Imaging Analysis Ltd | — |
| Unknown | Fluid Resuscitation In Trauma: What Are The Best Strategies And Fluids? NCT05738265 | Assiut University | — |
| Not Yet Recruiting | Effect of Balanced Saline Solution and Albumin on Volume Expansion in Shock Patients NCT05463471 | Peking Union Medical College Hospital | Phase 4 |
| Completed | CONFOCAL-2 Interventional Pilot Study NCT07296029 | Queen's University | Phase 1 / Phase 2 |
| Recruiting | Pharmacodynamic Analysis of the HaemOdynamic Effects of a Standard Fluid BolUS NCT06839404 | Bicetre Hospital | — |
| Unknown | Reliability of PVI Changes During Tidal Volume Challenge in ICU Patients NCT05428423 | Bicetre Hospital | — |
| Recruiting | Microvascular Monitoring in Circulatory Shock and Sepsis (MiMICSS) NCT05985525 | University of Manitoba | — |
| Completed | Impact of Integrated Cardiopulmonary Ultrasound on Clinical Outcome of Shocked Patients in Intensive Care Unit NCT06295445 | Egymedicalpedia | N/A |
| Terminated | Trendelenburg as a First-line Intervention in Critically Ill, Sedated, Invasively Mechanically Ventilated, Hyp NCT05209737 | Negovsky Reanimatology Research Institute | N/A |
| Completed | Thoracic Fluid Content by Bioimpedance-based Starling System NCT05676723 | Bicetre Hospital | — |
| Completed | Arterial and End-Tidal CO2 Gradient as a Mortality Predictor in Critical Care Patients NCT05341258 | Gaziosmanpasa Research and Education Hospital | N/A |
| Completed | Predicting Fluid Responsiveness During Shock in Newborns and Infants by End-expiratory Occlusion Test NCT04932590 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | Methylene Blue for the Prevention of Hypotension During Hemodialysis NCT05092165 | Federal University of São Paulo | Phase 2 |
| Unknown | LV Diastolic Function vs IVC Diameter Variation as Predictor of Fluid Responsiveness in Shock NCT05066256 | Mahidol University | N/A |
| Withdrawn | Comparing Post Cardiac Surgery Outcomes in ESRD Patient's With Early Dialysis Versus Standard Care NCT04705701 | Northwell Health | N/A |
| Completed | Role of Echocardiography in Guiding Fluid Therapy in Shocked Patients With Impaired Cardiac Contractility in E NCT05488730 | Alexandria University | N/A |
| Completed | The IndONEsia ICCU Registry: a Multicenter Cohort of Intensive Cardiovascular Care Units Patients in Indonesia NCT06265714 | Indonesia University | — |
| Unknown | NIVIA-Hemodynamics NCT06330597 | University Health Network, Toronto | — |
| Unknown | Assessment of the Hemodynamic Effect of Hydroxocabalamin in Refractory Vasodilatory Shock NCT04964492 | Centre Hospitalier Universitaire, Amiens | — |
| Completed | Rapid Treatment of Shock Without Trauma NCT05073354 | Zoll Medical Corporation | — |
| Unknown | Predicting Fluid Responsiveness in Mechanically Ventilated Critically Ill Children Using Transthoracic Echocar NCT05054452 | Assistance Publique - Hôpitaux de Paris | N/A |
| Unknown | Analysis of Passive Leg Raise Test on Blood Pressure in Critically Ill Patients. NCT05554783 | Medical University of Gdansk | — |
| Completed | Midodrine for the Early Liberation of Vasopressor Support in the ICU NCT04489589 | University of Alberta | Phase 4 |
| Unknown | Respiratory Variation of Superior Vena Cava in Transthoracic View as a Fluid Responsiveness Predictor NCT05211765 | University of Chile | — |
| Recruiting | Resuscitative TEE Collaborative Registry NCT04972526 | University of Pennsylvania | — |
| Completed | Lung Ultrasound Score and Pediatric Intensive Care Outcomes (LUS-PICO) NCT04660448 | Fundación para la Investigación Biosanitaria del Principado de Asturias | — |
| Completed | REmimazolam Infusion in the Context of Hypnotic Shortage in the Critical Care Unit During the Pandemic of COVI NCT04611425 | Nantes University Hospital | Phase 2 |
| Completed | Using Artificial Intelligence (AI)-Assisted Pulse Diagnosis Analysis on Precision Critical Medicine. NCT04675424 | Chang Gung Memorial Hospital | — |
| Completed | Evaluation of Microcirculatory Function and Mitochondrial Respiration After Cardiovascular Surgery NCT05330676 | University of Pennsylvania | — |
| Recruiting | Acutelines: a Large Data-/Biobank of Acute and Emergency Medicine NCT04615065 | University Medical Center Groningen | — |
| Completed | Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis NCT04102371 | Children's Hospital of Philadelphia | Phase 3 |
| Completed | Angiotensin II in the Perioperative Management of Hypotension in Kidney Transplant Recipients NCT04529005 | University of Illinois at Chicago | Phase 4 |
| Unknown | Endothelial Function, Inflammation and Organ Dysfunction in COVID-19 NCT04408365 | Guy's and St Thomas' NHS Foundation Trust | — |
| Completed | The Application of Point-of-care Ultrasonography in Differential Diagnosis of Shock in Emergency and Critical NCT04478045 | National Taiwan University Hospital | — |
| Suspended | VItamin C in Thermal injuRY: The VICToRY Trial NCT04138394 | Clinical Evaluation Research Unit at Kingston General Hospital | Phase 3 |
| Completed | Central Venous Oxygen Saturation and Carbone Dioxide (CO2)-Derived Indices in the Critically: NCT05220696 | University Hospital, Montpellier | — |
| Unknown | Peer Support for Post Intensive Care Syndrome Self-Management NCT03788096 | University of Texas at Austin | N/A |
| Completed | Intravascular Access in Suspected/Confirmed COVID-19 Patient NCT04366947 | Lazarski University | N/A |
| Completed | Renin as a Biomarker of Haemodynamic Normalisation NCT04303455 | South West Sydney Local Health District | — |
| Completed | Hemodynamic Characteristics of Patients With SARS-CoV-2 NCT04337983 | Bicetre Hospital | — |
| Completed | Direct Assessment of Microcirculation In Shock (DAMIS) NCT04173221 | Heinrich-Heine University, Duesseldorf | N/A |
| Unknown | Early Haemadsorption in Major Burns NCT04195126 | University of Pecs | N/A |
| Unknown | Optic Nerve Sheath Diameter in Prediction of Fluid Responsiveness NCT04092036 | Tanta University | — |
| Completed | VOLume and Vasopressor Therapy in Patients With Hemodynamic instAbility NCT04089098 | University of Leipzig | — |
| Unknown | Postoperative Respiratory Abnormalities NCT04079829 | Efficacy Care R&D Ltd | — |
| Completed | Correlation Between Changes in End-Tidal Carbon Dioxide and Stroke Volume Variation Detected by Electrical Car NCT03932617 | Tanta University | — |
| Unknown | Surrogate of Adequate Perfusion: Bladder Tissue Oxygen Monitoring NCT03935477 | University College London Hospitals | — |
| Unknown | Brain Ultrasound With Contrast Microbubbles Injection in Shock Status NCT04290767 | Universitair Ziekenhuis Brussel | N/A |
| Unknown | Applicability of Fluid Responsiveness Indices in Circulatory Failure (AFRIC Study) Study Project NCT05046340 | Bicetre Hospital | — |
| Recruiting | Impact of Endothelial and Leukocyte Senescence in Circulatory Shock States NCT03559569 | University Hospital, Strasbourg, France | — |
| Completed | Cerebral Circulation in Critically Ill Children NCT03731104 | Assistance Publique - Hôpitaux de Paris | — |
| Completed | Psychological Trauma and Resilience After Critical Illness NCT05193123 | Nantes University Hospital | — |
| Completed | Value of Cardiac Output Monitoring by Supra-sternal Doppler/Echocardiography in Intensive Care Unit NCT03952871 | CHU de Reims | — |
| Completed | Impact of Early Low-Calorie Low-Protein Versus Standard Feeding on Outcomes of Ventilated Adults With Shock NCT03573739 | Nantes University Hospital | N/A |
| Unknown | Simple Observational Critical Care Studies NCT03553069 | University Medical Center Groningen | — |
| Unknown | Assessment of the Link Between Monomeric Functional Form Plasma Level of Vasostatin-1 and Occurrence of New On NCT03457155 | University Hospital, Strasbourg, France | N/A |
| Unknown | Bedside Visual Analysis of Sublingual Microcirculation in Shock Patients NCT03406598 | Assistance Publique - Hôpitaux de Paris | — |
| Unknown | Cellular Immunotherapy for Septic Shock NCT03369275 | Ottawa Hospital Research Institute | Phase 2 |
| Completed | ClearSight Validation in Pediatrics NCT03701646 | Nemours Children's Clinic | — |
| Withdrawn | Extension of the RUSH Protocol for Volume Responsiveness NCT03285269 | Kaiser Permanente | — |
| Unknown | Cerebral Oxygenation and Neurological Outcomes FOllowing CriticAL Illness-2 NCT03141619 | Dr. Gordon Boyd | — |
| Completed | Point of Care Ultrasonography In The Management of Shock: A Pilot Study NCT03296891 | Western University, Canada | N/A |
| Completed | Variation in Fluids Administered in Shock NCT03190408 | Montefiore Medical Center | — |
| Unknown | Crystalloids for AKI in Shock Patients NCT03188614 | Southeast University, China | N/A |
| Unknown | Different Crystalloids on AKI in Shock NCT03155126 | Southeast University, China | — |
| Terminated | Thiamine vs. Placebo to Increase Oxygen Consumption After Cardiac Arrest NCT02974257 | Beth Israel Deaconess Medical Center | Phase 2 |
| Completed | Critical Care Ultrasound Oriented Shock Treatment in ICU NCT03093987 | West China Hospital | N/A |
| Completed | Balanced Crystalloid vs. Saline in Children With Septic Shock NCT02835157 | All India Institute of Medical Sciences | N/A |
| Completed | The Use of LiDCOplus in Fluid Resuscitation Decision-Making NCT03349749 | NHS Greater Glasgow and Clyde | — |
| Completed | Diagnostic Investigation and Prediction of Shock NCT03043170 | Cardiff University | — |
| Completed | The Acute Burn Resuscitation Multicenter Prospective Observational Trial NCT03144427 | American Burn Association | — |
| Completed | Continuous Central Venous Lactate Monitoring by Intravascular Microdialysis : a Comparison to Sequential Arter NCT03464747 | Centre Hospitalier Universitaire de Nīmes | — |
| Unknown | ΔvapCO2 / Cav02 Ratio as a Prognostic Marker and Predictor of Complications After Cardiac Surgery NCT02876406 | Hospital San Carlos, Madrid | — |
| Terminated | Optimization of Therapeutic Human Serum Albumin Infusion in Selected Critically Ill Patients NCT02755155 | University Hospital, Strasbourg, France | Phase 4 |
| Completed | AFrican Resuscitation Ultrasound In Critically-ill Adults NCT02794909 | Rockefeller Oteng | N/A |
| Unknown | Comparison of Allows Measurement of Cardiac Output Between Clearsight System and Transpulmonary Thermodilution NCT02728791 | University Hospital, Brest | — |
| Terminated | Evaluation of Three Dimensional Echocardiography in Critical Care Medicine NCT03270319 | Insel Gruppe AG, University Hospital Bern | — |
| Completed | The CCUS Based Characteristic of Hemodynamic and Lung Pathology in Early Stage of Shock in ICU: The Epidemic a NCT03082326 | West China Hospital | — |
| Completed | Physiologic Study of Cerebral Perfusion NCT02744625 | Centre de recherche du Centre hospitalier universitaire de Sherbrooke | Phase 4 |
| Terminated | Hemodynamic Instability Index: The Impact to Care With a New Predictive Indicator NCT02185521 | Philips Healthcare | N/A |
| Completed | Tranexamic Acid Mechanisms and Pharmacokinetics in Traumatic Injury NCT02535949 | Washington University School of Medicine | Phase 2 |
| Terminated | RApid Fluid Volume EXpansion in Patients in Shock After the Initial Phase of Resuscitation. NCT02645851 | Centre Hospitalier Régional d'Orléans | N/A |
| Terminated | Impact of Amount of Fluid for Circulatory Resuscitation on Renal Function in Patients in Shock NCT02666404 | University Hospital, Basel, Switzerland | N/A |
| Completed | Evaluation of Soluble ST2 in Patients Receiving Primary PCI With ST-elevation Myocardial Infarction NCT02830217 | Wuhan Asia Heart Hospital | — |
| Unknown | Focus Cardiac Ultrasound in Patients With Shock NCT04028297 | Nantes University Hospital | — |
| Unknown | GapCO2 and Respiratory Rate in Patients Under Volume Mechanical Ventilation NCT02867943 | 105 Hospital of Chinese People's Liberation Army | — |
| Completed | Strong Ion Gap as Prognostic Indicator for Adult Patients Admitted With Shock to the Intensive Care Units NCT02652364 | Singapore General Hospital | — |
| Unknown | CHangeovers of Norepinephrine in Intensive Care NCT02304939 | University Hospital, Angers | N/A |
| Completed | Simple Intensive Care Studies I (SICS-I) NCT02912624 | University Medical Center Groningen | — |
| Completed | Evaluation of the Pharmacokinetics of Caspofungin in ICU Patients NCT02596984 | Centre Hospitalier Universitaire de Saint Etienne | N/A |
| Completed | Implementation of a Web Based Real Time Clinical Decision Support Tool. NCT02398981 | Mayo Clinic | N/A |
| Terminated | Impact of Early Enteral vs. Parenteral Nutrition on Risk of Gastric-Content Aspiration in Patients Requiring M NCT03411447 | Centre Hospitalier Departemental Vendee | N/A |
| Terminated | Impact of Early Enteral vs. Parenteral Nutrition on Preservation of Gut Mucosa Integrity in Patients Requiring NCT03852940 | Centre Hospitalier Departemental Vendee | N/A |
| Completed | Better Arterial Cannulation Technique With Different Hemodynamics NCT02825615 | Sultan Qaboos University | N/A |
| Unknown | Normal Saline Versus Balance Salt Solution Resuscitation on Kidney Function NCT02520804 | Mahidol University | N/A |
| Completed | Evolution of Molecular Biomarkers in Acute Heart Failure Induced by Shock NCT02141607 | Shockomics Consortium | — |
| Terminated | Phenylephrine Versus Norepinephrine for Septic Shock in Critically Ill Patients NCT02203630 | Vanderbilt University Medical Center | Phase 4 |
| Completed | The Impact of Point-of-Care Ultrasound NCT03276364 | Montefiore Medical Center | — |
| Completed | Systolic Blood Pressure Measurement in Critically-ill Patients NCT02366507 | Wake Forest University Health Sciences | — |
| Completed | The Impact of Fellow-performed Cardiopulmonary Ultrasound Exams NCT02186197 | Beth Israel Medical Center | — |
| Completed | Steroid Use in Pediatric Fluid and Vasoactive Infusion Dependent Shock - Pilot Study NCT02044159 | Children's Hospital of Eastern Ontario | Phase 4 |
| Terminated | Dobutamine in the Treatment of Haemodynamic Insufficiency in the Immediate Postnatal Period NCT03311178 | Fundacion para la Investigacion Biomedica del Hospital Universitario la Paz | Phase 1 / Phase 2 |
| Recruiting | Vasoactive Drugs in Intensive Care Unit NCT02118467 | University of Chicago | Phase 4 |
| Completed | Effects of Hemodynamic Monitoring Using the ImaCor Single Use Transesophageal Echocardiography Probe in Critic NCT02048566 | Insel Gruppe AG, University Hospital Bern | N/A |
| Completed | Succinylcholine vs Rocuronium for Prehospital Emergency Intubation NCT02000674 | Centre Hospitalier Universitaire de la Réunion | Phase 3 |
| Completed | The Checklist for Early Recognition and Treatment of Acute Illness (CERTAIN) NCT01973829 | Mayo Clinic | N/A |
| Completed | Proving Hemodilution in a Human Model for Class I Hemorrhage NCT02318355 | Wake Forest University Health Sciences | N/A |
| Completed | Transcutaneous pO2, Transcutaneous pCO2 and Central Venous SO2 Variations to Define Fluid Responsiveness NCT01941472 | Peking Union Medical College Hospital | N/A |
| Completed | Urinary Heparanase Activity as a Predictor of Acute Kidney Injury in Critically Ill Adults NCT01900275 | Denver Health and Hospital Authority | — |
| Completed | Pediatric Fast Fluid Trial 2 NCT01774214 | McMaster Children's Hospital | N/A |
| Completed | Optimal VAsopressor titraTION Pilot Randomized Controlled Trial NCT01800877 | Francois Lamontagne | N/A |
| Completed | Patient Centered Cloud-based Electronic System: Ambient Warning and Response Evaluation (ProCCESs AWARE) NCT02039297 | Mayo Clinic | N/A |
| Completed | Impact of Early Enteral vs. Parenteral Nutrition on Mortality in Patients Requiring Mechanical Ventilation and NCT01802099 | Centre Hospitalier Departemental Vendee | N/A |
| Terminated | High Dose Vitamin C in the Critically Ill Patient NCT01587963 | Rutgers, The State University of New Jersey | Phase 2 |
| Completed | Noninvasive Assessment of Tissue Perfusion Status in Critically Ill Pediatric Patients NCT01760044 | University of Michigan | N/A |
| Completed | Echocardiographic Prediction of Fluid Responsiveness After a Mini-fluid Challenge in Non-ventilated Patients W NCT01590511 | Centre Hospitalier Universitaire de Nīmes | — |
| Completed | Non-Invasive Shock: Differentiating Shock in the Emergency Department NCT02164851 | Beth Israel Deaconess Medical Center | — |
| Terminated | PICU Admission Lactate and Central Venous Oxymetry Study NCT01696175 | Radboud University Medical Center | — |
| Completed | Non-Invasive Ventilation Via a Helmet Device for Patients Respiratory Failure NCT01680783 | University of Chicago | N/A |
| Completed | The Use of the USCOM Device in Addition to Cardiac Ultrasound in Patients Undergoing Treatment for Undifferent NCT01981629 | Hennepin Healthcare Research Institute | — |
| Terminated | Single Dose Enteral Tranexamic Acid in Critically Ill Patients NCT01683747 | San Diego Veterans Healthcare System | Phase 2 |
| Unknown | BWH Critical Care Study of CareGuide for Evaluation of Emerging or Established Shock NCT03060369 | Brigham and Women's Hospital | — |
| Completed | Tissue Near InfraRed Spectroscopy (NIRS) in Critically Ill Patients NCT01528358 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | — |
| Completed | HEAVy HAT-HEAlthy Volunteers Heart to Arm Time. Haemorrhage Simulation Protocol in Healthy Volunteers NCT02177188 | University of Milano Bicocca | N/A |
| Unknown | Safety Study of Shenmai(a Chinese Medicine Injection) Used in Hospitals in China NCT01612611 | China Academy of Chinese Medical Sciences | — |
| Completed | Pancreatic Exocrine Insufficiency and Pancreatic Enzyme Supplementation in Critically Ill Adult Patients NCT01753024 | Shanghai 10th People's Hospital | — |
| Unknown | Vasopressin Versus Norepinephrine for the Management of Shock After Cardiac Surgery NCT01505231 | University of Sao Paulo | Phase 3 |
| Unknown | Safety Study of Shenfu (a Chinese Medicine Injection) Used in Hospitals in China NCT01612533 | China Academy of Chinese Medical Sciences | — |
| Completed | Predicting Volume Response Study NCT01656954 | University of Pennsylvania | — |
| Unknown | Effect of Monitoring of Pulse Index Continuous Cardiac Output (PiCCO) on Shock Patients in Intensive Care Unit NCT01397188 | Li danyang | N/A |
| Completed | Sonography in Hypotension and Cardiac Arrest in the Emergency Department. NCT01419106 | Horizon Health Network | N/A |
| Withdrawn | Pre Hospital Evaluation of Video Laryngoscopy NCT01374061 | Assistance Publique - Hôpitaux de Paris | Phase 4 |
| Completed | Clinical Investigation of Wireless Transmission of Invasive Blood Pressure Signal NCT01373996 | University Medical Centre Ljubljana | — |
| Completed | The Effects of Sedative on the Fluid Responsiveness in Critically Ill Patients NCT01447875 | Southeast University, China | Phase 1 |
| Completed | Effects of Sedatives on Sublingual Microcirculation of Patients With Septic Shock NCT01618396 | Casa de Saúde São José | N/A |
| Completed | Hemoglobin Saturation in Superior Vena Cava and Right Atrium NCT01398436 | Catholic University of the Sacred Heart | N/A |
| Terminated | Observational Study of Blood Pressure Measurements and Continuous Dialysis NCT01286506 | University of Chicago | — |
| Completed | Studies of Blood DNA in Patients With Severe Infection DYNAMICS NCT01355042 | Alison Fox-Robichaud | — |
| Terminated | Emergency Department (ED) Flow-directed Fluid Optimization Resuscitation Trial (EFFORT) NCT01128413 | Washington University School of Medicine | N/A |
| Completed | Vasopressin in Traumatic Hemorrhagic Shock Study NCT00379522 | Volker Wenzel | Phase 2 / Phase 3 |
| Completed | Hydrogen Sulfide as Prognostic Factor NCT01088490 | University Medical Centre Ljubljana | — |
| Completed | High Volume Veno-venous Hemofiltration Versus Standard Care for Post-cardiac Surgery Shock NCT01077349 | Assistance Publique - Hôpitaux de Paris | N/A |
| Unknown | Hemodynamic Evaluation of Preload Responsiveness in Children by Using PiCCO NCT01157299 | Hospital Universitario La Paz | — |
| Unknown | Assessment of Transcutaneous Oxygen Tension/Oxygen Challenge Test in Intensive Care Unit (ICU) Patients NCT01174966 | Peking Union Medical College Hospital | — |
| Terminated | The Effect of Erythropietin on Microcircualtory Alteration in Intensive Care Unit Patients With Severe Sepsis NCT01087450 | London Health Sciences Centre | — |
| Unknown | An Upgrading of the Resuscitative Patterns by Utilization of the Balanced Crystalloids and Synthetic Colloids NCT00914563 | Faculty Hospital Kralovske Vinohrady | Phase 2 |
| Unknown | Validation of the Fluid Responsiveness Index in Critically Ill Patients NCT00894309 | Bicetre Hospital | — |
| Completed | Study Comparing High Cut-off Haemofiltration With Standard Haemofiltration in Acute Renal Failure NCT00912184 | Austin Health | Phase 1 / Phase 2 |
| Unknown | Chloride High Level Of Resuscitation Infusion Chloride High Level Of Resuscitation Infusion Delivered Evaluati NCT00885404 | Austin Health | Phase 4 |
| Completed | Total Body Albumin Measurement Utilizing a Modification of the BVA 100 Blood Volume Analyzer NCT01542749 | Daxor Corporation | — |
| Completed | Posterior Tibial Artery Bypass for Iliofemoral Artery Injury Associated With Massive Blood Loss and Shock NCT00900848 | The Second Hospital of Qinhuangdao | — |
| Completed | Impact of Traumatic Brain Injury on Hemodynamic Instability in Patients With Blunt Bowel and Mesenteric Injuri NCT06942091 | Chang Gung Memorial Hospital | — |
| Completed | Effect of Nebulized Bronchodilators on Heart Rate NCT01151579 | Fahim Khorfan, MD | Phase 4 |
| Completed | Brachial Artery Peak Velocity Variation to Predict Fluid Responsiveness NCT00890071 | Hospital del SAS de Jerez | — |
| Completed | Hemodynamic Efficiency of an Hemodialysis Treatment With High Permeability in Post-resuscitation Shock NCT00780299 | Assistance Publique - Hôpitaux de Paris | Phase 3 |
| Unknown | Norepinephrine as Early Vasopressor Therapy in Children Undergoing Mechanical Ventilation NCT00894621 | Unidade de Terapia Intensiva | Phase 4 |
| Completed | Clinical Evaluation of Swallowing Disorders as a Predictor of Extubation Failure NCT00780078 | Assistance Publique - Hôpitaux de Paris | — |
| Completed | Programming Implantable Cardioverter Defibrillators in Patients With Primary Prevention Indication NCT00743522 | Abbott Medical Devices | — |
| Completed | NT-proBNP in ICU Postoperative/Posttraumatic Patients With Shock NCT00736723 | University of Ulm | — |
| Completed | Enhanced Surveillance of RV Lead Integrity Alert (RVLIA) NCT00824915 | Medtronic | — |
| Withdrawn | Presep and Vascath Interaction Study NCT00739089 | Wake Forest University Health Sciences | — |
| Completed | Fluid Responsiveness Prediction at the Bedside NCT00721604 | Fondazione Poliambulanza Istituto Ospedaliero | — |
| Completed | Out-of-Hospital Intubation With Metal Single Use Laryngoscope Blades NCT00644722 | Henri Mondor University Hospital | Phase 4 |
| Unknown | Oxidative Stress in Critical Ill Patients in Surgical Intensive Care Unit NCT00745888 | National Taiwan University Hospital | — |
| Terminated | Enteral Glutamine Supplementation for the Patient With Major Torso Trauma NCT00178581 | The University of Texas Health Science Center, Houston | Phase 1 |
| Completed | Effects of Alkaline Phosphatase on Renal Function in Septic Patients NCT00457613 | Radboud University Medical Center | Phase 2 |
| Completed | Comparison of Central and Peripheral Venous Catheters NCT00122707 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | Dopamine and Norepinephrine in Shock Patients NCT00314704 | Sepsis Occurrence in Acutely Ill Patients | Phase 3 |
| Completed | Hypertonic Saline With Dextran for Treating Hypovolemic Shock and Severe Brain Injury NCT00113685 | University of Washington | N/A |
| Completed | Safety and Efficacy of PHP in the Treatment of Shock Associated With Systemic Inflammatory Response Syndrome ( NCT00021502 | Apex Bioscience | Phase 3 |
| Unknown | Evaluation of the Quality of the NovoSeven (rFVIIa) Tratment Practice at Rigshospitalet, Copenhagen University NCT00192933 | Rigshospitalet, Denmark | — |
| Unknown | Bedside Ultrasound Measurement of the Inferior Vena Cava Correlates to Central Venous Pressure NCT00596921 | Brooke Army Medical Center | — |