Clinical Trials Directory

Trials / Sponsors / University of Leipzig

University of Leipzig

Academic / Other · 145 registered clinical trials23 currently recruiting.

StatusTrialPhaseStarted
RecruitingValidation of Energy Expenditure Measures Study
Obesity Prevention, Healthy
2025-08-26
RecruitingSmartWatch-driven AF Detection in Stroke Patients
Atrial Fibrillation (AF), Ischemic Stroke, ECG Monitoring
N/A2025-05-15
RecruitingA Contrast Medium Sparing Strategy Using Automated CO2 Injection During PVI for Prevention of Major Adverse Ki
Peripheral Vascular Diseases, Kidney Diseases
Phase 32025-04-14
Not Yet RecruitingPeripheral Drivers of Heart Failure Progression - the Prospective PEDAL-HF Study
Heart Failure - NYHA II - IV
N/A2024-11-01
RecruitingCholesterol Self-testing in Patients Post Acute Coronary Syndrome
Acute Coronary Syndrome, Prevention, LDL Hyperlipoproteinemia
N/A2024-06-01
RecruitingEuropean Larynx Organ Preservation Study (ELOS) [MK-3475-C44]
Squamous Cell Carcinoma of Head and Neck, Hypopharyngeal Squamous Cell Carcinoma, Laryngeal Squamous Cell Carcinoma Stage III
Phase 22024-04-17
RecruitingINDIcators for Clarifying the bAckground of exTreme Obesity in childRen
Gene Abnormality, Child Obesity, Hunger
2024-04-15
Active Not RecruitingFeasibility of Home-based Cardiac Rehabilitation in Patients With Chronic Heart Failure (Pilot-CRHF)
Heart Failure
N/A2024-02-29
RecruitingComparison of a Lithotripsy vs Standard Preparation Followed by Stenting With Supera Stent in Femoropopliteal
Peripheral Arterial Disease
N/A2024-02-13
RecruitingThe Pancreatic Enzymes After Gastrectomy Trial
Gastrectomy
Phase 32024-01-24
RecruitingpotentiALS - Quality of Life Among Patients With Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
2024-01-01
RecruitingVirtual Interactive 3D Modelling to Improve Outcomes in Robotic-Assisted Partial Nephrectomy
Kidney Tumor
N/A2023-10-24
RecruitingVenetoclax in Combination with 5 Days Azacitidine in Untreated AML Patients, Not Eligible for Standard Inducti
Acute Myeloid Leukemia (AML)
Phase 22023-05-17
RecruitingCardiac Amyloidosis Registry of University Hospital Leipzig
Cardiac Amyloidosis
2023-05-01
RecruitingTreatment of Non-resectable Bile Duct Cancer with Radiofrequency Ablation or Photodynamic Therapy
Hilar Cholangiocarcinoma
Phase 42023-02-10
Active Not RecruitingStudy Investigating Patient-Reported Outcomes in Lower-risk MDS Patients
MDS, MDS/MPN
2022-10-11
Active Not RecruitingPROVE ACURATE neo2™ - Post Market Safety and Performance Surveillance in Aortic Stenosis
Aortic Stenosis
2022-10-04
RecruitingEfficacy of Luspatercept in ESA-naive LR-MDS Patients With or Without Ring Sideroblasts Who do Not Require Tra
Myelodysplastic Syndromes, Anemia
Phase 22022-09-27
UnknownLaboratory Study for the Acquisition of Spectral and Photoplethysmographic Data
Healthy Volunteers
2022-08-22
TerminatedEfficacy and Safety of Canakinumab for the Treatment of Anemia in LR-MDS Patients
Anemia, Myelodysplastic Syndromes
Phase 22022-04-26
TerminatedTreatment of Anemia in Patients With Very Low, Low or Intermediate Risk Myelodysplastic Syndromes With CA-4948
Myelodysplastic Syndromes, Anemia
Phase 22022-01-01
CompletedCabozantinib Treatment in a Phase II Study for Patients With Hepatocellular Carcinoma (HCC) Refractory to PD-1
Hepatocellular Carcinoma
Phase 22021-12-14
RecruitingRenal Denervation to Treat Heart Failure With Preserved Ejection Fraction
Heart Failure With Preserved Ejection Fraction, Hypertension, Renal
N/A2021-11-30
Active Not RecruitingPulmonary Vein Isolation vs SHAM-pulmonary Vein Isolation for Symptomatic Relief in Patients With AF
Atrial Fibrillation
N/A2021-11-12
Active Not RecruitingStatin-Intolerance Registry
Dyslipidemias
2021-08-01
CompletedImpact of Hospitalization on High-sensitivity Cardiac Troponin T Concentrations Depending on Disease Severity
Non-cardiac Disease
2021-07-14
UnknownNasal High-flow Compared to Non-invasive Ventilation in Treatment of Acute Acidotic Hypercapnic Exacerbation o
COPD Exacerbation Acute
N/A2021-05-06
RecruitingEffects of Cross-sex Hormone Therapy on Eating Behavior, Metabolism, Energy Balance and Cardiovascular System
Transsexualism, Transgenderism, Adiposity
2021-05-05
CompletedCMR T1 Mapping for Diagnosis of Cardiac Amyloidosis
Heart Failure NYHA Class II, Heart Failure NYHA Class III, Heart Failure NYHA Class IV
2021-04-01
RecruitingPeer2Me: A Peer Supported Program for Adolescent and Young Adult Cancer Patients
Cancer, Psychosocial Problem
N/A2021-01-01
CompletedTreatment of MDS/AML Patients With an Impending Hematological Relapse With AZA or ATA and Pevonedistat
Acute Myeloid Leukemia in Remission, Myelodysplastic Syndromes, Minimal Residual Disease
Phase 22021-01-01
UnknownThe Obese Taste Bud Study
Obesity
2020-11-09
CompletedRotational Thromboelastometry Versus DIC Score in Sepsis
Sepsis, Septic Shock
2020-11-02
CompletedInfluence of Renal Replacement TherApy on Indirect Calorimetry
Acute Renal Failure, Mechanical Ventilation
2020-10-20
Active Not RecruitingDiagnosing Heart Failure With Preserved Ejection Fraction in Patients With Unexplained Dyspnea (Diagnose-HFpEF
Dyspnea
2020-09-09
CompletedHemodynamic Effects of ARNI on Noninvasive Pressure-volume Analysis in Patients With Chronic Heart Failure
Heart Failure With Reduced Ejection Fraction
2020-07-21
UnknownChild and Parent-directed Individualized Psychotherapy (CPIP)
Child Neglect, Internalizing Disorder
N/A2020-07-21
Active Not RecruitingIntensive Rhythm Monitoring to Decrease Ischemic Stroke and Systemic Embolism - the Find-AF 2 Study
Ischemic Stroke, Atrial Fibrillation
N/A2020-07-07
CompletedTreatment of Early Childhood Depression
Depression
N/A2020-02-24
UnknownICG vs. HSI in Gastrointestinal Resections
Anastomosis, Perfusion
N/A2020-01-02
UnknownLongitudinal Analysis of Mental Disorders, Psychosocial Distress and Care Needs of Patients and Their Relative
Neoplasm Malignant
2020-01-01
CompletedDiagnosis-related Outcomes in NeurocriTical Care: Prognostic Estimate by Health-care Providers Versus Risk Sco
Intracerebral Hemorrhage, Subarachnoid Hemorrhage
2019-12-12
UnknownProspective, Multicenter Cohort Study on Primary Biliary Cholangitis
PBC, Primary Biliary Cholangitis
2019-09-19
CompletedVOLume and Vasopressor Therapy in Patients With Hemodynamic instAbility
Hemodynamic Instability, Shock, Septic Shock
2019-09-01
UnknownTissue Characterization With Hyperspectral Imaging (HSI)
Tissue Perfusion, Tumor, Inflammation
N/A2019-06-06
CompletedELECT Trial - Embolization of the Lumbar Arteries Before EVAR
Aortic Aneurysm
N/A2019-03-01
CompletedPsychological Therapy for Patients With ALS
Amyotrophic Lateral Sclerosis, Psychological Stress
N/A2019-02-11
Active Not RecruitingBEST SFA Pilot Study - Best Endovascular STrategy for Complex Lesions of the Superficial Femoral Artery
Peripheral Arterial Disease
N/A2019-01-01
UnknownOral Antibiotic Prophylaxis in Colorectal Surgery
Surgical Site Infection, Anastomotic Leak
2018-12-17
Active Not RecruitingParaplegia Prevention in Aortic Aneurysm Repair by Thoracoabdominal Staging
Aortic Aneurysm, Thoracoabdominal
N/A2018-11-08
UnknownInfluence of Systemic Parameters in Diabetic Macular Edema - LIPSIA Study
Diabetic Macular Edema, Macular Edema, Retinal Vein Occlusion
2018-09-01
CompletedCBT on Fatigue in Survivors of Hodgkin Lymphoma
Hodgkin Lymphoma, Fatigue
N/A2018-08-20
CompletedPostoperative aRCH With Cisplatin Versus aRCH With Cisplatin and Pembrolizumab in Locally Advanced Head and Ne
HNSCC
Phase 22018-08-06
UnknownIntraoperative Hyperspectral Imaging in Gastrointestinal Anastomoses
Surgical Anastomosis
N/A2018-08-01
RecruitingMucous Fistula Refeeding Reduces the Time From Enterostomy Closure to Full Enteral Feeds ("MUC-FIRE" Trial)
Enterostomy
N/A2018-06-18
CompletedCatheter Ablation Versus Amiodarone for Therapy of Premature Ventricular Contractions in Patients With Structu
Heart Diseases, Cardiomyopathies, Ventricular Premature Complexes
Phase 32017-11-01
CompletedCardiovascular Magnetic Resonance-Guided Radiofrequency-Ablation for Atrial Flutter II
Atrial Flutter
N/A2017-03-30
TerminatedReturn to Work and Living Healthy After Head and Neck Cancer
Head and Neck Cancer
N/A2017-01-01
UnknownAcute Impact of the Impella CP Assist Device in Pts. With Cardiogenic Shock on the Patients Hemodynamic
Cardiogenic Shock
N/A2016-12-01
CompletedNecessity of Transnasal Gastroscopy in Routine Diagnostics - a Patient Centered Requirement Analysis
Patient Safety
N/A2016-09-01
UnknownImpact of Left Atrial Appendage Closure on Physical Capacity.
Atrial Fibrillation
2016-08-01
CompletedCombination of NHF and Nebulizer on Lung Function in COPD
Chronic Obstructive Pulmonary Disease
N/A2016-08-01
CompletedPostoperatively Treated Patients With Lower Limb Fracture With or Without an Anti-gravity Treadmill
Muscle Degeneration
N/A2016-08-01
CompletedMetacognitive Therapy for Obsessive-Compulsive Disorder
Obsessive-Compulsive Disorder (OCD)
N/A2016-06-01
UnknownRegister Study of Patients With Peritoneal Carcinomatosis Treated With PIPAC (Pressurized Intra-peritoneal Aer
Peritoneal Carcinomatosis
2016-04-01
TerminatedCardiovascular Magnetic Resonance-Guided Radiofrequency-Ablation for Atrial Flutter
Atrial Flutter
N/A2016-03-01
UnknownClinical Intervention Modelling, Planning and Proof for Ablation Cancer Treatment
Hepatocellular Carcinoma, Liver Metastases
N/A2016-02-01
CompletedGranulocyte Colony Stimulating Factor (G-CSF) to Treat Acute-on-chronic Liver Failure
Acute-On-Chronic Liver Failure
N/A2016-02-01
CompletedEffect of Nasal Highflow on Right Heart Function
Pulmonary Hypertension
N/A2016-01-01
CompletedTalking Time: Telephone Support Groups for Informal Caregivers of People With Dementia
Caregivers of People With Dementia
N/A2015-11-01
TerminatedAlfapump System Versus Transjugular Intrahepatic Portosystemic Shunt and Paracentesis in the Treatment of Asci
Liver Cirrhosis
N/A2015-11-01
CompletedCompare I Pilot Study for the Treatment of Subjects With Symptomatic Femoropopliteal Artery Disease
Peripheral Artery Disease
N/A2015-10-01
CompletedNon-invasive Liver Screening for Risk Assessment for Coronary Heart Disease
Coronary Disease, Non-alcoholic Fatty Liver Disease, Elasticity Imaging Techniques
2015-10-01
UnknownInternet-based Perioperative Exercise Program in Patients With Barrett's Carcinoma Scheduled for Esophagectomy
Barrett Esophagus
N/A2015-08-01
CompletedInfluence of an Anti-gravity Treadmill on Functional Outcome in Non-operatively Treated Pelvic Fractures - a P
Weight-bearing, Rehabilitation
N/A2015-05-01
TerminatedRadio Frequency Ablation for Atrial Flutter With Magnetic Resonance Guidance and Tracking
Atrial Flutter
N/A2015-01-01
CompletedLaparoscopic vs Robotic-Assisted Radical Prostatectomy
Prostate Cancer
N/A2014-11-01
CompletedIdentification of Biomarkers for Prediction of Response or Resistance Against Target Therapy in Gastric Cancer
Esophageal Neoplasms, Stomach Neoplasms
2014-03-01
CompletedProof of Concept Study of Re-treatment in BRVO With Ranibizumab Guided by OCT
Branch Retinal Vein Occlusion
Phase 22013-10-01
UnknownCLaret Embolic Protection ANd TAVI - Trial
Frequency of Cerebral Perfusion Defects After TAVI, Size of Cerebral Perfusion Defects After TAVI
N/A2013-04-01
CompletedGerman Evaluation of the Effectiveness of the Psychological Intervention Managing Cancer and Living Meaningful
Depression, Psychological Distress
N/A2013-03-01
CompletedGerman Adaptation of REACH II
Dementia, Family Caregiver
N/A2012-10-01
CompletedMild Hypothermia in Cardiogenic Shock Complicating Myocardial Infarction
Acute; Myocardial Infarction, Complications, Cardiogenic Shock
N/A2012-08-01
CompletedRenal Sympathetic Denervation in Mild Refractory Hypertension
Refractory Hypertension
Phase 42012-07-01
CompletedThe Use of CO2 in Routine-Colonoscopy
Colonoscopy
N/A2012-04-01
CompletedStepped Care - Optimising Psycho-oncological Care Provision by Structured Screening and Diagnosis
Cancer
N/A2012-04-01
CompletedEffect of Conditioning on Myocardial Damage in STEMI
ST-elevation Myocardial Infarction
N/A2011-10-01
CompletedPelvic Belt Effects on Osseous Anatomy, Muscule Activation and Ground Reaction Forces
Sacroiliac Joint Pain, Helath Related Quality of Life, Electromuscular Activation of the Pelis and Limbs
N/A2011-08-01
CompletedPhysiological and Clinical Changes in NHF Therapy
Chronic Obstructive Pulmonary Disease, Hypercapnia, Interstitital Lung Disease
N/A2011-06-01
CompletedEffectiveness of TNI vs. BiPAP in Chronic Global Insufficiency in COPD Patients
COPD Chronic Obstructive Pulmonary Disease
N/A2011-06-01
CompletedEffect of Thrombus Aspiration in Patients With Myocardial Infarction Presenting Late After Symptom Onset
Myocardial Infarction
Phase 42011-06-01
CompletedComparison Between Winged Versus Traditional Plastic Stents for Biliary Drainage
Biliary Obstruction, Bile Duct Stones, Biliary Tract Cancer
N/A2011-06-01
UnknownEffects of Different Exercise Training Regimens on Visceral Fat Dynamic and Resting Energy Expenditure in Obes
Abdominal Obesity
N/A2011-04-01
CompletedThrombus Aspiration in ThrOmbus Containing culpRiT Lesions in Non-ST-Elevation Myocardial Infarction (TATORT-N
Non-ST-elevation Myocardial Infarction
Phase 42011-03-01
CompletedAdiponectin and Circulating Progenitor Cells (CPC) Function
Coronary Artery Disease
Phase 12011-01-01
CompletedImpact of Implantation of an LAA Occluder on ANP and BNP Level and Quality of Life
Atrial Fibrillation
2011-01-01
RecruitingLeipzig Adipose Tissue Childhood Cohort
Childhood Obesity, Insulin Resistance
2010-10-01
RecruitingLIFE Child (LIFE Leipzig Research Centre for Civilization Diseases)
Child Development
2010-10-01
UnknownAtrial and Brain Natriuretic Peptide Secretion After Percutaneous Closure of the Left Atrial Appendage
Atrial Fibrillation, Stroke Prevention, Left Atrial Appendage
N/A2010-05-01
CompletedImpact of Intensive Exercise Training on Coronary Collateral Circulation in Patients With Stable CAD
Stable Coronary Artery Disease
N/A2010-03-01
UnknownFollow up After Survived Therapy With Mild Induced Hypothermia (MIH) After Restoration of Spontaneous Circulat
Cardiac Arrest, Hypothermia
2010-01-01
UnknownTreatment With Lenalidomide, Bendamustine and Prednisone (RBP) in Patients With Relapsed or Refractory Multipl
Multiple Myeloma
Phase 1 / Phase 22009-09-01
CompletedIntraaortic Balloon Pump in Cardiogenic Shock II
Myocardial Infarction, Shock, Cardiogenic
Phase 42009-06-01
TerminatedComparison of Individual Computer Aided Design/Manufactured (CAD/CAM) - Based Implants Consisting on Hydroxyla
Skull Defects, Cranioplasty
Phase 32009-06-01
WithdrawnImmeDiate Versus EArLy Invasive Approach in Non-ST-Elevation Myocardial Infarction (IDEAL NSTEMI)
Non-ST-elevation Myocardial Infarction
N/A2009-01-01
CompletedReproducibility of Magnetic Resonance Myocardial Salvage Index
Myocardial Infarction
2008-11-01
CompletedTime-Dependent Mobilization of Circulating Progenitor Cells During Strenuous Exercise in Healthy Individuals
Healthy Men
N/A2008-09-01
CompletedAbciximab i.v. Versus i.c. in ST-elevation Myocardial Infarction
ST-elevation Myocardial Infarction
Phase 32008-07-01
CompletedCOOL-Trial: Outcome With Invasive and Non-invasive Cooling After Cardiac Arrest
Cardiac Arrest, Hypothermia
Phase 42008-04-01
CompletedNeuron Specific Enolase (NSE) as Outcome Parameter of Cooling Therapy After Survived Sudden Cardiac Death
Cardiac Arrest, Hypothermia
2008-04-01
CompletedChanges of Biomarkers in Response to Training and Antioxidant Treatment
Obesity, Type 2 Diabetes
Phase 12008-03-01
CompletedEffect of Different Dosages of Dark Chocolate on Arterial Blood Pressure in Cardiovascular High-risk Patients
Hypertension
Phase 42008-02-01
CompletedImpact of Polymorphism on Pulmonary Pressure in Subjects With Pulmonary Hypertension of Different Cause
Congestive Heart Failure, Pulmonary Hypertension
2007-12-01
CompletedChronic Inflammatory Activation in Fat Tissue: an Atherogenic Factor in Stable Coronary Artery Disease
Stable Coronary Artery Disease, Obesity, Impaired Glucose Tolerance
N/A2007-07-01
TerminatedChronic Inflammatory Activation in Fat Tissue: An Atherogenic Factor in Severe Coronary Artery Disease
Severe Coronary Artery Disease, Obesity, Impaired Glucose Tolerance
N/A2007-07-01
CompletedLongitudinal Assessment of Cardiovascular and Metabolic Parameters in Obese and Lean Children
Obesity
2007-04-01
CompletedRight Ventricular Hypertrophy After Atrial Switch and Cardiovascular Magnetic Resonance (CMR) Findings
Right Ventricular Hypertrophy, d-TGA
2007-04-01
UnknownGenetic- and Biological-Markers of Predisposition to Atherosclerosis: Leipzig-Heart Study
Atherosclerosis, Coronary Arteriosclerosis, Carotid Artery Diseases
2006-12-01
CompletedMyocardial Salvage and Contrast Dye Induced Nephropathy Reduction by N-Acetylcystein
Myocardial Infarction
Phase 32006-12-01
CompletedMyocardial Salvage Assessed by Cardiovascular Magnetic Resonance - Impact on Outcome
ST-Elevation Myocardial Infarction
2006-11-01
CompletedYUKON Choice Versus TAXUS Liberté in Diabetes Mellitus
Coronary Arteriosclerosis
Phase 42006-09-01
CompletedRandomized Trial of Immediate Versus Early and Selective Invasive Percutaneous Coronary Intervention in NSTEMI
Myocardial Infarction
Phase 42006-07-01
TerminatedMitral Valve Reconstruction in Chronic Heart Failure (CHF): Identification of Predictors for a Successful Ther
Chronic Heart Failure, Mitral Insufficiency
Phase 22006-06-01
CompletedExercise Versus Niacin in Patients With Coronary Artery Disease (CAD) and Low High-Density Lipoproteins (HDL)
Coronary Disease, Hypolipoproteinemia
Phase 42006-03-01
CompletedRight Ventricular Damage in Cardiovascular Magnetic Resonance
Acute Myocardial Infarction
2006-02-01
CompletedAbciximab i.v. Versus i.c. in Primary PCI Patients With STEMI
Myocardial Infarction
Phase 2 / Phase 32006-01-01
WithdrawnImprovement of Physical Activity and Correction of Body Mass Index in School Children
Overweight
N/A2005-07-01
CompletedLeipzig Exercise Intervention in Chronic Heart Failure and Aging
Heart Failure, Ageing
Phase 22005-05-01
CompletedComparison of the OSHO Protocol to a Standard Arm Protocol of the German AML Intergroup in Patients With AML>6
Acute Myeloid Leukaemia
Phase 32005-04-01
CompletedAphasia Therapy: Factors of Efficacy
Aphasia
N/A2005-03-01
CompletedValue of Cardiac Magnetic Resonance (CMR) Derived Parameters for Diagnosing Left Ventricular Non-compaction Ca
Left Ventricular Non-compaction Cardiomyopathy, Left Ventricular Failure, Left Ventricular Hypertrophy
2004-12-01
CompletedTreatment of CML Patients With Imatinib and Hydroxyurea (CML2004)
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Phase 1 / Phase 22004-04-01
CompletedImpact of Rosuvastatin on Endothelial Function and Inflammation in Patients With Chronic Heart Failure
Heart Failure
Phase 22004-03-01
CompletedPhysical Exercise Versus Rosiglitazone in CAD and Prediabetes
Impaired Glucose Tolerance
Phase 42004-01-01
UnknownPercutaneous Coronary Intervention (PCI) With Drug-Eluting Stents (DES) Versus Coronary Artery Bypass Graft (C
Coronary Stenosis, Coronary Artery Disease
Phase 22003-08-01
WithdrawnCutaneous Lupus Erythematosus and Elidel
Lupus Erythematosus, Cutaneous, Lupus Erythematosus, Discoid
N/A2003-06-01
CompletedImpact of Exercise Training on Exercise Capacity in Patients With Severe Chronic Heart Failure
Heart Failure
Phase 22003-03-01
UnknownStatin Therapy in Asymptomatic Aortic Stenosis
Aortic Valve Stenosis
Phase 22003-01-01
CompletedMIDCAB Versus DES in Proximal LAD Lesions
Coronary Artery Disease
N/A2003-01-01
UnknownComparison of the OSHO Protocol to a Standard Arm Protocol of the German AML Intergroup in Patients With AML<6
Acute Myeloid Leukaemia
Phase 32002-04-01
RecruitingLeipzig Childhood Obesity Study
Childhood Obesity
2002-01-01
UnknownImpact of Exercise Training on Endothelial Function in CAD
Coronary Artery Disease
Phase 22001-01-01
RecruitingCrescNet - Growth Monitoring Network
Obesity, Child Development, Growth Disorders
1998-01-01
WithdrawnPioglitazone in Impaired Glucose Tolerance
Glucose Metabolism Disorders
Phase 4
UnknownPercutaneous Coronary Angioplasty Compared With Exercise Training in Symptomatic Coronary Artery Disease
CAD, Stable Angina Pectoris
Phase 2 / Phase 3