Trials / Completed
CompletedNCT01272674
Adiponectin and Circulating Progenitor Cells (CPC) Function
Adiponectin Promotes the Migration of Circulating Progenitor Cells Through p38-mediated Induction of the CXCR4 Receptor
- Status
- Completed
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 20 (actual)
- Sponsor
- University of Leipzig · Academic / Other
- Sex
- Male
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Accepted
Summary
Adiponectin and exercise training contribute to the maintenance of a normal vascular tone by influencing vascular NO bioavailability and concentration and function of endothelial progenitor cells. The molecular mechanisms are only partially understood. Therefore, aim of the present study is to elucidate the effects of Adiponectin on endothelial progenitor cell migration and the underlying signaling pathways. Furthermore, the impact of exercise training on adiponectin-mediated endothelial progenitor cell migration will be investigated.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | exercise training | 4 weeks supervised physical exercise training |
Timeline
- Start date
- 2011-01-01
- Primary completion
- 2011-03-01
- Completion
- 2011-03-01
- First posted
- 2011-01-10
- Last updated
- 2015-06-02
Locations
1 site across 1 country: Germany
Source: ClinicalTrials.gov record NCT01272674. Inclusion in this directory is not an endorsement.