NCT02007772

Effectiveness of TNI vs. BiPAP in Chronic Global Insufficiency in COPD Patients

Effectiveness of TNI (Nasal High-flow) vs. BiPAP (Biphasic Positive Airway Pressure) in Chronic Global Insufficiency in COPD (Chronic Obstructive Pulmonary Disease) Patients

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 105 (actual)
• Sponsor: University of Leipzig · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this trial ist to investigate the difference of the efficacy of two systems for breath support in patients with COPD.

Detailed description

The trial consists of 12 weeks of therapy that is divided into two sections. In the first 6-week section patients receive treatment with either TNI or BiPAP and in the second 6-week section treatment is changed. The starting therapy is allocated to the patients via randomisation and should be started directly after the baseline visit. The treatment and the follow-up period end with the second visit after the second treatment section and the patient decides which device he/she wants to use further.

Conditions

• COPD Chronic Obstructive Pulmonary Disease

Interventions

Type	Name	Description
DEVICE	nHF	nasal high-flow is used over a period of 6 weeks (outpatient)
DEVICE	BiPAP	BiPAP is used over a period of 6 weeks (outpatient)

Timeline

• Start date: 2011-06-01
• Primary completion: 2017-07-01
• Completion: 2017-07-01
• First posted: 2013-12-11
• Last updated: 2018-11-15

Locations

14 sites across 1 country: Germany