| Not Yet Recruiting | Impact of Combined Cardio-pulmonary Assessment on COPD Clinical Management. NCT07481825 | University of Bari Aldo Moro | N/A |
| Not Yet Recruiting | A Repeat Ascending Dosing Study of the Safety and Clinical Activity of R-3750 in Patients With Mild to Moderat NCT07076290 | Rise Therapeutics LLC | Phase 1 |
| Not Yet Recruiting | The REVIVE Pivotal Study NCT07361653 | Ryme Medical, Inc. | N/A |
| Not Yet Recruiting | Repeat Treatment With Metered Cryospray in Patients With Chronic Obstructive Pulmonary Disease With Chronic Br NCT07468617 | CSA Medical, Inc. | N/A |
| Not Yet Recruiting | Inhaler Training to Enhance Nurses' Competency in Patient Inhaler Education NCT07527455 | Hong Kong Metropolitan University | N/A |
| Recruiting | Real-World Effectiveness of a Triple Combination BDP/FF/GB Extrafine in a Single Pressurised Metered Dose Inha NCT07406048 | Chiesi Farmaceutica Ltda. | — |
| Enrolling By Invitation | Effect of High-intensity Interval Training on the Lung in Patients With COPD Referred for Lung Volume Reductio NCT07343375 | Rigshospitalet, Denmark | N/A |
| Not Yet Recruiting | Mobile Health Self-Management Intervention for Patient With Chronic Obstructive Pulmonary Disease NCT07469904 | Universitas Katolik Widya Mandala Surabaya | N/A |
| Recruiting | Emotional-distress-based Integrated Care Programme in Patients With Stable COPD NCT07524023 | University of Zurich | N/A |
| Enrolling By Invitation | Probiotics in COPD: Effects on Symptoms, Lung Function, and Inflammation NCT07339280 | University Hospital of Split | N/A |
| Recruiting | COPD Exacerbation Follow Up NCT07118306 | Viz.ai, Inc. | — |
| Not Yet Recruiting | The Effects of Manual Therapy on the Spatiotemporal Gait Characteristics in Patients With Chronic Obstructive NCT07381842 | Hacettepe University | N/A |
| Not Yet Recruiting | Prevalence and Functional Impact of Urinary Incontinence in Women With Chronic Obstructive Pulmonary Disease U NCT07134400 | Fondation Hôpital Saint-Joseph | — |
| Not Yet Recruiting | Home-based Pulmonary Rehabilitation for COPD Patients NCT04820257 | Karolinska Institutet | N/A |
| Not Yet Recruiting | The Efficacy of Non-invasive Brain Stimulation on Cognitive Functions in Patients With Chronic Obstructive Pul NCT07332169 | Shahad Abdulrahman Alkandari | N/A |
| Not Yet Recruiting | Digital High-Intensity Respiratory Muscle Training on COPD Patients NCT07346261 | Cairo University | N/A |
| Not Yet Recruiting | A Study to Investigate the Biomarkers of Hemay005 in Adult Participants With Moderate to Severe COPD NCT07314242 | Ganzhou Hemay Pharmaceutical Co., Ltd | Phase 2 |
| Recruiting | Heart Failure With Preserved Ejection Fraction in Patients With Сhronic Obstructive Pulmonary Disease: Clinica NCT07375433 | National Medical Research Center for Therapy and Preventive Medicine | — |
| Not Yet Recruiting | Self-management Digital Intervention to Promote Physical Activity in People Living With COPD NCT07262229 | Institut et Haute Ecole de la Santé la Source | N/A |
| Not Yet Recruiting | Impact of Home Non Invasive Ventilation in Patients With Chronic Obstructive Pulmonary Disease Discharged From NCT07198880 | Assiut University | N/A |
| Not Yet Recruiting | A Study to Understand the Accuracy of a New Breathing Device Compared to Standard Testing for Asthma and COPD NCT07253883 | Liverpool Heart and Chest Hospital NHS Foundation Trust | — |
| Recruiting | How Nocturnal Hypoventilation Predicts Long-term Response to Non-invasive Ventilation in Hypercapnic COPD Pati NCT07414108 | IRCCS Azienda Ospedaliero-Universitaria di Bologna | — |
| Recruiting | Combined Posture Correction and Resistive Respiratory Muscles Training in COPD With FHP NCT07293429 | Riphah International University | N/A |
| Active Not Recruiting | Changing Outcomes Through Achievement Emails in COPD Using Routine Healthcare Audits NCT07181915 | University of Leeds | N/A |
| Not Yet Recruiting | Effects of Blood Flow Restriction Aerobic Exercise on Inflammation, Hypoxia, Exercise Capacity, and Lung Funct NCT07261293 | Istinye University | N/A |
| Not Yet Recruiting | Development And Evaluation of An Adaptive Web-Based Intervention for COPD NCT06770777 | University of Colorado, Denver | N/A |
| Not Yet Recruiting | Chronic Obstructive Pulmonary Disease, Quality of Life, COPD Assessment Test, Nepal, Dyspnea, Spirometry NCT07261813 | Institute of medicine, Maharagjung medical campus | — |
| Enrolling By Invitation | Improving Adherence to COPD Treatments in Primary Care NCT07104136 | Tel-Aviv Sourasky Medical Center | N/A |
| Recruiting | Photon-counting CT in Chest Imaging NCT07031336 | Duke University | N/A |
| Recruiting | A Phase IIa, Randomized, Double-Blind, Placebo-Controlled Trial of JKN2403 in COPD NCT07351734 | Joincare Pharmaceutical Group Industry Co., Ltd | Phase 2 |
| Not Yet Recruiting | The Effect of BIPAP on Diaphragmatic Function NCT07193017 | Istanbul Demiroglu Bilim University | — |
| Recruiting | Using Multiomics to Define Mechanisms of Rhinovirus-induced Chronic Obstructive Pulmonary Disease Exacerbation NCT07112235 | Imperial College London | — |
| Recruiting | Evaluation of the Paramedic Evaluation for Acute COPD Exacerbation NCT07072039 | University of Massachusetts, Worcester | N/A |
| Recruiting | Comprehensive Maintenance Program: a Health Haven for COPD in Lleida.The NAPOLEON Project. NCT07394712 | Institut de Recerca Biomèdica de Lleida | N/A |
| Recruiting | Inhaled Treprostinil (Tyvaso Nebulizer) For COPD Patients With Hypoxemia NCT07037836 | Bastiaan Driehuys | Phase 2 |
| Active Not Recruiting | Pulmonary and Total Blood Volume in COPD NCT07428785 | Rigshospitalet, Denmark | — |
| Recruiting | Clinical Study of the Pulsed Electric Field Ablation System in Chronic Obstructive Pulmonary Disease NCT07068438 | Suzhou Hengruihongyuan Medical Technology Co. LTD | N/A |
| Recruiting | Pulmonary Rehabilitation in Salt Chambers for Patients With COPD NCT07122544 | University School of Physical Education, Krakow, Poland | N/A |
| Not Yet Recruiting | Survey on NIV Settings in the Intensive Care Unit for Acute Exacerbation of COPD NCT06888180 | University Hospital, Caen | — |
| Not Yet Recruiting | Cardio-circulatory and Respiratory Monitoring for Prediction of Outcome in Mechanically Ventilated Chronic Obs NCT07109206 | Assiut University | — |
| Recruiting | Validation of Chronic Obstructive Pulmonary Disease (COPD) Algorithm NCT07223749 | Wake Forest University Health Sciences | — |
| Recruiting | GRACE - Graduated Response for Advanced COPD With Enhanced Support NCT06967324 | Copenhagen University Hospital, Hvidovre | N/A |
| Active Not Recruiting | Effect of Rehabilitation on the Respiratory Signal in Patients With COPD and Exercise-Induced Desaturation NCT07107828 | Eastern Switzerland University of Applied Sciences | N/A |
| Completed | Safety and Efficacy of JKN2304 Inhalation Solution in Patients With Moderate to Severe COPD NCT07450482 | Joincare Pharmaceutical Group Industry Co., Ltd | Phase 2 |
| Recruiting | University of Michigan COPD Identification Through Lung Cancer Screening Cohort Study - MAP2 NCT07482475 | University of Michigan | — |
| Recruiting | Investigation of the Attitudes of Patients With Chronic Obstructive Pulmonary Disease Towards Traditional Comp NCT07031401 | Kutahya Health Sciences University | — |
| Recruiting | Effectiveness of DITM Versus IMT in COPD Patients NCT06958666 | Sir Run Run Shaw Hospital | N/A |
| Enrolling By Invitation | Effect of Silymarin as Add on Therapy on Oxidative Stress, Pulmonary Function and Quality of Life in Stable CO NCT07123922 | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | N/A |
| Enrolling By Invitation | Effect of an App-based Intervention on Air Pollution in COPD Patients NCT07074093 | Fundacion para la Investigacion y Formacion en Ciencias de la Salud | N/A |
| Completed | Effects of VR Training on Balance and Fall Risk of Patients With COPD NCT06604754 | Riphah International University | N/A |
| Recruiting | Inhaled Treprostinil for Dyspnea and Exercise Intolerance in Mild COPD NCT06969573 | University of Alberta | Phase 2 |
| Recruiting | Medical Device Clinical Trial Without CE Marking to Evidence Safety and Performance of the INBENTUS VERSATILE NCT07432191 | Iconic Solutions By Murcia SL | N/A |
| Not Yet Recruiting | Hemodynamic Responses and Brain Activity During Dual Tasks in COPD Patients Versus Healthy Individuals NCT06974448 | Hacettepe University | — |
| Recruiting | Internet-Based Cognitive Behavioral Therapy and Educational Program for People Living With Chronic Obstructive NCT06891677 | Jonas Agholme | N/A |
| Not Yet Recruiting | The Effect of Mask Design on Ventilation Parameters in COPD and OHS Patients on Long-term Home Non-invasive Ve NCT06972589 | Fisher and Paykel Healthcare | N/A |
| Not Yet Recruiting | Respiratory Oxygen Adherence Monitor for Chronic Obstructive Pulmonary Disease Patients NCT06874101 | Barron Associates, Inc. | N/A |
| Not Yet Recruiting | Oscillometry in the COPD Exacerbator Phenotype With Triple Inhaled Therapy Study NCT06931899 | Hospital Universitari de Bellvitge | — |
| Recruiting | Virtual Pulmonary Rehabilitation Program for COPD Patients; a Pilot Study NCT06915740 | Turku University Hospital | N/A |
| Recruiting | Mathematical Analysis of Signals and Clinical Parameters Provided by Non-invasive Home Ventilation Devices NCT07267104 | Corporacion Parc Tauli | — |
| Not Yet Recruiting | Effects of Vibrating Mesh Nebulisation in Patients With COPD During Non-invasive Ventilation (VMN-NIV) NCT06884228 | Guy's and St Thomas' NHS Foundation Trust | N/A |
| Withdrawn | Eecentric Exercise on Cardiopulmonary Fitness and Quality of Life With Chronic Obstructive Pulmonary Disease NCT06869720 | Fu Jen Catholic University | N/A |
| Recruiting | Cardiovascular Assessment and Treatment During COPD Exacerbation to Improve Diagnosis and Outcomes NCT06723795 | Tel-Aviv Sourasky Medical Center | N/A |
| Not Yet Recruiting | Psilocybin Therapy for Psychological Distress in Palliative Patients NCT06782724 | University Medical Center Groningen | Phase 2 |
| Completed | A Randomized, Safety and Efficacy Study of Taneasy 600mg Granules and Fluimucil 600mg Granules in COPD Subject NCT06828120 | Bun Yao Biotechnology Co., Ltd | Phase 4 |
| Recruiting | Respiratory Rehabilitation and Sleep Quality in COPD Patients NCT06677268 | University Hospital, Rouen | N/A |
| Not Yet Recruiting | Metoprolol in Patients With HFrEF and COPD NCT06825728 | Xiangya Hospital of Central South University | Phase 4 |
| Completed | Comparison of Thoracic Squeeze and Manual Diaphragmatic Release Technique in COPD Patients NCT06791239 | Riphah International University | N/A |
| Recruiting | Prospective and Multicentric Cohort Study of Severe and Very Severe Chronic Obstructive Pulmonary Disease (COP NCT06724315 | Hospital Israelita Albert Einstein | — |
| Recruiting | Study That Will Evaluate the Brazilian Population With COPD. NCT06780046 | AstraZeneca | — |
| Recruiting | Assessment of Breathing Pattern During NIV NCT06682286 | Fisher and Paykel Healthcare | N/A |
| Completed | Risk Indicators and IPI Performance in Sedation-Related Respiratory Deterioration in COPD NCT07262905 | Umran Karaca | — |
| Recruiting | The REDUCE EU Study - Endobronchial Thermal Liquid Ablation (ETLA) for the Treatment of Emphysema NCT06655428 | Morair Medtech, LLC | N/A |
| Not Yet Recruiting | Vitamin C's Antioxidant Effects and COPD Prognosis NCT06664957 | Ningbo No. 1 Hospital | N/A |
| Completed | Can Total Mechanical Power Be a Determinant of Weaning Failure in Chronic Obstructive Pulmonary Disease (COPD) NCT06751654 | Bakirkoy Dr. Sadi Konuk Research and Training Hospital | — |
| Recruiting | Probiotics in Pulmonaty Rehabilitation for COPD NCT06717659 | Fu Jen Catholic University | N/A |
| Active Not Recruiting | Floor-Lift Series Pulmonary Rehabilitation for COPD: Short- and Long-Term Outcomes in a North African Setting NCT07277855 | Benazzouz Redouene Sid Ahmed | N/A |
| Active Not Recruiting | Acupuncture for Persistent Dyspnea Despite Medical Treatment in COPD NCT07058259 | Istanbul Medeniyet University | N/A |
| Recruiting | Effect of Aronia Berry Consumption on Inflammatory Parameters NCT06702696 | Amasya University | N/A |
| Active Not Recruiting | Clinical Pilates Programme on People With COPD Gold A: a Rehabilitation Nursing Approach. NCT07267858 | University of Trás-os-Montes and Alto Douro | N/A |
| Recruiting | Routine vs On-demand ECMO for Lung Transplantation NCT06615492 | Centre hospitalier de l'Université de Montréal (CHUM) | N/A |
| Recruiting | Exploring How Viral Infections Affect People With Chronic Lung Disease NCT06625944 | Imperial College London | — |
| Recruiting | Validation of the French Version of the QASCI in Caregivers of Patients With COPD NCT06652204 | University Hospital, Brest | — |
| Completed | Respiratory Muscle Strength and Exercise Capacity in Smokers NCT06650150 | Muğla Sıtkı Koçman University | — |
| Completed | End-Inspiratory Pause in COPD Patients During Controlled Ventilation NCT07207967 | Sanatorio Anchorena San Martin | N/A |
| Active Not Recruiting | Investigation of the Effects of Different Exercise Approaches on Clinical Parameters in Chronic Obstructive Pu NCT06680960 | Hacettepe University | N/A |
| Completed | The Safety and Effectiveness of Taneasy and Actein in COPD Patients NCT06688292 | Bun Yao Biotechnology Co., Ltd | Phase 4 |
| Active Not Recruiting | Comparison of Clinical Parameters in Chronic Obstructive Pulmonary Disease Patients and Healthy Individuals NCT06677671 | Hacettepe University | — |
| Recruiting | The Effectiveness of Self-Management Education and Telephone Follow-up in Patient with COPD Exacerbation NCT06707649 | Kirsehir Ahi Evran Universitesi | N/A |
| Active Not Recruiting | Effects of Rehabilitation and Supplementation With Hydrolyzed Collagen vs. Whey Protein on the Cardiopulmonary NCT07011225 | Federal University of São Paulo | Phase 4 |
| Recruiting | The Effects of Different Vibration Exercises on COPD Patients NCT06413524 | Taipei Medical University | N/A |
| Active Not Recruiting | A Phase 2 Trial of JKN24011 in COPD NCT07440524 | Joincare Pharmaceutical Group Industry Co., Ltd | Phase 2 |
| Active Not Recruiting | Effect of Electrical Diaphragmatic Stimulation on Chronic Obstructive Pulmonary Disease NCT07020299 | Mansoura University Hospital | N/A |
| Completed | High Intensity Interval Training and Inspiratory Muscle Training NCT06836895 | Prince Sattam Bin Abdulaziz University | N/A |
| Completed | The Effect of Forgiveness-based Motivational Interviewing NCT07365943 | Ömer USLU | N/A |
| Completed | Sarcopenia Predictors in Patients With COPD NCT07509528 | Hacettepe University | — |
| Recruiting | Digital Follow-up Program for People with Chronic Obstructive Pulmonary Disease in Primary Healthcare NCT06401512 | Western Norway University of Applied Sciences | N/A |
| Completed | The Impact of Extreme Heat Waves and Air Pollution on the Prognosis of Chronic Airway Diseases NCT07261774 | Mersin University | — |
| Enrolling By Invitation | Coronary Computed Tomography Angiography In Rheumatoid Arthritis Study NCT07363980 | Ellen Margrethe Hauge | — |
| Recruiting | A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on NCT06283966 | AstraZeneca | Phase 3 |
| Recruiting | Assessing Functional Capacity in Directly and Remotely Monitored Home-based Settings: A Protocol for a Multina NCT06447831 | Laval University | — |
| Active Not Recruiting | The Effect of Acupressure on Dyspnea and Anxiety Levels NCT06752915 | ÇİĞDEM ERGİN | N/A |
| Completed | A Study to Investigate the Effect on Lung Function of an Approved COPD Treatment (BGF, With HFA Propellant) Co NCT06075095 | AstraZeneca | Phase 3 |
| Active Not Recruiting | A Study to Investigate GB-0895 in Adults With Mild to Moderate Asthma or COPD NCT07116889 | Generate Biomedicines | Phase 1 |
| Recruiting | Compare the Effects of Nebulizer Versus Inhaler Based Therapy for COPD Using Long-acting Bronchodilators NCT07133880 | University of Tennessee Graduate School of Medicine | Phase 4 |
| Unknown | A Pilot Observation and Feasibility Study of Prevora, Integrated Into Homecare Visits of High-risk Adults NCT06158633 | CHX Technologies Inc. | — |
| Completed | ELECTROVEST: Electro-Stimulation Vibratory Vest for Pulmonary Rehabilitation in Patients With Chronic Respirat NCT07175012 | Hospitales Universitarios Virgen del Rocío | N/A |
| Completed | Respiratory Exercises in Frail Elderly COPD Patients NCT07472530 | Çankırı Karatekin University | N/A |
| Unknown | China Elderly Comorbidity Medical Database NCT06316544 | Beijing Friendship Hospital | — |
| Recruiting | Rehabilitation in Safety-net Environments (RISE) to Improve Outcomes in Vulnerable Patients With COPD NCT05572632 | University of California, San Francisco | N/A |
| Completed | Evaluation in Elderly Individuals with Chronic Obstructive Pulmonary Disease(COPD) NCT05811832 | Kırıkkale University | — |
| Completed | Automated Oxygen Titration in Daily Life in Patients With COPD on Home Oxygen NCT05553847 | Hvidovre University Hospital | N/A |
| Completed | The Improvement of Indoor Air and Health Effects After Air Purifier Intervention Among Susceptible Population NCT07069907 | Kaohsiung Medical University Chung-Ho Memorial Hospital | N/A |
| Recruiting | OMEGA - Dietary Intervention - COPD Trial NCT05297279 | Johns Hopkins University | N/A |
| Completed | Risk Factors, Costs, and Impacts of ED Boarding NCT07532564 | University of Maryland, Baltimore | — |
| Unknown | Effect of BDP/Formoterol/G on Cough Efficacy in Moderate to Severe COPD Patients (EFFICACE) NCT05114434 | University of Parma | — |
| Unknown | GOLD 0 - DLCO 1: A Look Beyond the Obstruction. Is Spirometry Enough for COPD (Chronic Obstructive Pulmonary D NCT05016466 | Fundación para la Investigación del Hospital Clínico de Valencia | — |
| Completed | Reduced COPD Related Utilization of Healthcare Services and Increased Social Activities by Patients Offered a NCT06988566 | ECM Klinikken APS | N/A |
| Unknown | Non Invasive Evaluation of Muscle Hypoxia in COPD Patient (EVANIMUS) NCT03921983 | University Hospital, Clermont-Ferrand | N/A |
| Completed | Motivational Interviewing and Air Cleaners for Smokers With COPD (MOVE COPD) NCT03658538 | Johns Hopkins University | N/A |
| Completed | RETHINC: REdefining THerapy In Early COPD for the Pulmonary Trials Cooperative NCT02867761 | University of Michigan | Phase 3 |
| Completed | A Study to Assess the Effects of PT001 and PT005 MDI on Specific Image Based Parameters in Subjects With Moder NCT02937584 | Pearl Therapeutics, Inc. | Phase 3 |
| Completed | Active Controlled Trial of CHF5993 Pressurized Metered-dose Inhaler ( pMDI) vs Symbicort®Turbuhaler® in Patien NCT03197818 | Chiesi Farmaceutici S.p.A. | Phase 3 |
| Completed | The Effect of Lt to Rt Shunt Using Veno-veno-arterial Extracorporeal Membrane Oxygenation (ECMO) on Coronary O NCT02859194 | Yonsei University | N/A |
| Unknown | Evaluation of Reactive Oxygen Metabolites in the Value of COPD NCT02297633 | Beijing Chao Yang Hospital | — |
| Withdrawn | Progressive Resistance Training of the Extensor Muscle of the Thigh in COPD-patients Hospitalized With an Exac NCT01812460 | Frederikssunds Hospital, Denmark | N/A |
| Completed | Effectiveness of TNI vs. BiPAP in Chronic Global Insufficiency in COPD Patients NCT02007772 | University of Leipzig | N/A |
| Completed | Lung Cancer Risk in Type 2 Diabetes With COPD: SGLT2 Inhibitors vs. Sulfonylureas NCT07332156 | Samsung Medical Center | — |