NCT07107828

Effect of Rehabilitation on the Respiratory Signal in Patients With COPD and Exercise-Induced Desaturation

Effect of Rehabilitation on the Respiratory Signal in Patients With Chronic Obstrucitve Pulmonary Disease (COPD) and Exercise-Induced Desaturation

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 52 (actual)
• Sponsor: Eastern Switzerland University of Applied Sciences · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The aim is to study the effect of SSOT during a 3-week in-patient pulmonary rehabilitation programme. Further aim is to analyse exercise endurance, distinguishing between those exercising whilst breathing air at 760m "normoxia", breathing air at 1600m "hypoxia", or breathing SSOT at 760m "hyperoxia" conditions, during in-patient pulmonary rehabilitation. The objective of the main study is to provide long-awaited data concerning the use of SSOT during training. At present it is unclear whether patients with chronic lung diseases who reveal an SpO2 \> 88% at rest, but desaturate during exercise, and, thus, may not qualify for long-term oxygen undergoing PR benefit from supplemental oxygen. This sub-study will involve the subjects wearing the Respeck device and will focus on the effect of exercise on the respiratory signal measured by the Respeck.

Conditions

• COPD (Chronic Obstructive Pulmonary Disease)

Interventions

Type	Name	Description
OTHER	Ambient air	Standard ambient air will be breathed during endurance training.
OTHER	Oxygen	SSOT will be applied during endurance training
OTHER	Altitude	Training will be performed at moderate altitude

Timeline

• Start date: 2025-07-23
• Primary completion: 2025-12-31
• Completion: 2025-12-31
• First posted: 2025-08-06
• Last updated: 2025-08-06

Locations

1 site across 1 country: Kyrgyzstan