NCT03759886

Oral Antibiotic Prophylaxis in Colorectal Surgery

Mechanical Bowel Preparation and Oral Antibiotic Prophylaxis vs. Mechanical Bowel Preparation in Colorectal Surgery With i.v. Antibiotic Prophylaxis

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: University of Leipzig · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The investigators perform a case-control study to compare preparation before elective colorectal surgery. The first group is a prospective patient - registry in all patients with mechanical bowel preparation (MBP) and oral antibiotic prophylaxis the day before colorectal surgery. The second group is a historic collective of patients with MBP only and colorectal surgery. The cases were matches in American Society of Anesthesiologists (ASA) physical status classification system, BMI, operative procedure and risk factors.

Conditions

• Surgical Site Infection
• Anastomotic Leak

Interventions

Type	Name	Description
DRUG	Paromomycin Sulfate Powder	The patients receive Paromomycin and Metronidazole the day prior to colorectal surgery after mechanical bowel preparation

Timeline

• Start date: 2018-12-17
• Primary completion: 2020-05-01
• Completion: 2020-12-01
• First posted: 2018-11-30
• Last updated: 2020-01-07

Locations

1 site across 1 country: Germany