NCT01286506

Observational Study of Blood Pressure Measurements and Continuous Dialysis

Observational Study Evaluating the Hemodynamic Relationship Between Volume Removal and Pulse Pressure Variation During Renal Replacement Therapy

• Status: Terminated
• Phase: —
• Study type: Observational
• Enrollment: 7 (actual)
• Sponsor: University of Chicago · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Dialysis is used to control the fluid balance and metabolic state of patients with kidney disease. Control of the metabolic state, via electrolytes, can be monitored using labs that are routinely drawn from patients undergoing continuous hemodialysis. Control of fluid removal is much more difficult. This study aims to determine whether changes in the blood pressure associated with breathing correlate with or predict intolerance to fluid responsiveness with continuous dialysis. We hypothesize that a measurement of changes in blood pressure with breathing called arterial pulse pressure variation may be able to predict the ability to remove fluid during continuous renal replacement therapy.

Conditions

• Kidney Failure
• Respiratory Failure
• Critical Illness
• Shock

Timeline

• Start date: 2011-02-01
• Primary completion: 2015-12-01
• Completion: 2015-12-01
• First posted: 2011-01-31
• Last updated: 2016-08-31

Locations

1 site across 1 country: United States