Trials / Conditions / Respiratory Failure

Respiratory Failure

547 registered clinical trials studyying Respiratory Failure — 87 currently recruiting.

Status	Trial	Sponsor	Phase
Not Yet Recruiting	Mode of Ventilation During Critical Illness at Multiple Centers NCT07313956	Vanderbilt University Medical Center	N/A
Not Yet Recruiting	Quantification of Inspiratory Effort Through Nasal Pressure in Patients Undergoing Weaning From Invasive Mecha NCT05282238	University of Modena and Reggio Emilia	—
Not Yet Recruiting	Percutaneous Cryoablation of Intercostal Nerves for the Treatment of Rib Fractures NCT06533904	Loma Linda University	N/A
Not Yet Recruiting	Vela Generation II: Usability and Performance of a Non-Invasive Ventilation Mask. NCT07484802	Fisher and Paykel Healthcare	N/A
Not Yet Recruiting	Heart Rate VAriability as a MaRker for tItrATing hIgh flOw Nasal Cannula Therapy NCT07518862	University Health Network, Toronto	—
Not Yet Recruiting	Critical Care Admission Following Emergency Department's Resuscitation Room Care NCT07411976	Centre Hospitalier Universitaire de Nīmes	—
Recruiting	Supraglottic Airway for Resuscitation in Preemies NCT07419438	University of Pennsylvania	N/A
Recruiting	Benefit of Sleep Quality Monitoring by EEG in ICU NCT07522450	University Hospital, Rouen	—
Not Yet Recruiting	Impact of Biphasic Cuirass Ventilation Compared to Non Invasive Ventilation in High Risk Extubations NCT07067502	University of Missouri-Columbia	N/A
Recruiting	Transpulmonary Assessment for Individualized Lung Optimization in Obese Patients NCT07359261	University of Alberta	Phase 2
Not Yet Recruiting	EIT-Guided Respiratory Physiotherapy for Prolonged Mechanical Ventilation (PMV) NCT07372794	Capital Medical University	N/A
Not Yet Recruiting	Ventilator-based Inspiratory Muscle Training for Patients With Respiratory Failure NCT07353814	Cairo University	N/A
Not Yet Recruiting	Real-Time Algorithm-Driven Ventilation Feedback to Improve Lung-Protective Ventilation in Critically Ill Patie NCT07307066	Peking Union Medical College Hospital	N/A
Recruiting	Comparison of the Efficacy and Safety of Ciprofol Versus Propofol for Sedation in ICU Patients Undergoing Non- NCT07536750	Nanfang Hospital, Southern Medical University	—
Not Yet Recruiting	Influence of Chest X-ray vs. Chest CT Scan on the Management of ICU Patients With Respiratory Failure NCT07256860	Meir Medical Center	—
Not Yet Recruiting	HVNI vs NIPPV in Type 2 Respiratory Failure NCT07065656	National University Hospital, Singapore	N/A
Recruiting	A Trial Comparing High-Flow Nasal Cannula Versus Noninvasive Ventilation on Reintubation and Post-Extubation R NCT06671015	Yale University	N/A
Not Yet Recruiting	The Impact of Low Versus High Positive End-expiratory Pressure on Diaphragm Function, Ventilation Efficiency, NCT07188038	Vastra Gotaland Region	N/A
Recruiting	Spontaneous Breathing Trials Using Pressure Support or T-Piece in Overweight and Obese Patients NCT07114289	Taipei Medical University Hospital	N/A
Completed	Comparison of Ventilatory Effects of Ultrasound-Guided Versus Bronchoscopy-Guided Percutaneous Dilatational Tr NCT07376525	Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization	—
Not Yet Recruiting	Investigating the Impact of Sepsis Phenotypes on Antibiotic Treatment in Patients With Severe Pneumonia and Se NCT06977165	University of Manchester	—
Recruiting	The Effect of Music Therapy on Vital Signs and Heart Rate Variability of Pediatric Patients During the Extubat NCT06591533	Claudia Aristizábal	N/A
Not Yet Recruiting	ICU Background Early Awareness for Critical deterioratiON NCT07119411	ETH Zurich	—
Not Yet Recruiting	Safety, Tolerability and Performance of the NucleoCapture Device in the Reduction of Circulating CfDNA/NETs in NCT05647096	Santersus AG	N/A
Not Yet Recruiting	Volatile Anesthetic Pharmacokinetics During Extracorporeal Membrane Oxygenation NCT05680545	University Health Network, Toronto	N/A
Recruiting	A New Tool for Extubation Readiness in Mechanically Ventilated Patients: Readiness for EXtubation Score NCT07098611	Medipol University	—
Not Yet Recruiting	Early Speaking Valve in Ventilator Weaning: Effects on Communication, Depression, and Quality of Life NCT07005596	Far Eastern Memorial Hospital	N/A
Recruiting	Combining Chest X-Ray and Arterial Blood Gas Findings to Predict Need for Mechanical Ventilation in Critically NCT07001696	Zagazig University	—
Recruiting	Diaphragmatic Physiology Similarity Index May Titrate HFNC Flow Setting: A Prospective Observational Study NCT06996665	Sir Run Run Shaw Hospital	N/A
Recruiting	Noninvasive Technique and High Flow Nasal Oxygen in Respiratory Failure NCT07521254	Minia University	N/A
Not Yet Recruiting	Perioperative Risk Factors Related to the Prognosis of Lung Transplantation: A Retrospective Study NCT06922916	Zhejiang University	—
Completed	Use of Lactate-to-Albumin, CRP-to-Albumin, and Procalcitonin-to-Albumin Ratios to Predict Mortality in ICU Pat NCT07242027	Medical University of Silesia	—
Not Yet Recruiting	The Utility of Osteopathic Manipulative Medicine in Weaning Patients from the Ventilator Pilot Trial NCT06891248	Oklahoma State University Center for Health Sciences	N/A
Recruiting	Study of Platelet Population Changes Under Circulatory Support With ECMO NCT07334457	University Hospital, Strasbourg, France	—
Completed	Core Stability and Respiratory Parameters in Children With Thoracic Hyperkyphosis NCT06853548	Istinye University	—
Recruiting	SerpinB3 Expression, PAR2 and SCCA-PD Polymorphism in Acute Respiratory Distress Syndrome NCT06774534	University of Padova	—
Completed	Patients Comfort During Highflow Oxygen Therapy With Asymmetrical Prongs NCT06778291	University of Padova	—
Not Yet Recruiting	Effect of Different Proprioceptive Neuromuscular Facilitation Techniques Versus Flow Trigger Sensitivity on We NCT06831201	Beni-Suef University	Phase 1
Recruiting	Community Exercise Treating Effect on Cardiopulmonary Disease Patients NCT07154355	Guangdong Provincial People's Hospital	N/A
Active Not Recruiting	Intubation Checklist in the Intensive Care Unit NCT06791317	Karolinska University Hospital	—
Recruiting	Physiological Effect High-flow Tracheal Oxygen on Viscosity of Airway Mucus and Respiratory Effort in Patients NCT06776939	Henrik Endeman	N/A
Not Yet Recruiting	ROX Index Versus MROX Index to Predict Treatment Outcome for High Flow Nasal Cannula And/or Noninvasive Ventil NCT06715644	Assiut University	—
Active Not Recruiting	Evaluation and Optimization of Telephone Triage Using Artificial Intelligence (AI) Models for the Detection of NCT07247669	Centro de Emergencias Sanitarias 061 Andalucía	—
Recruiting	Impact of PEEP on Respiratory Effort During Assisted Ventilation NCT07437846	Pontificia Universidad Catolica de Chile	N/A
Active Not Recruiting	A Rapid Diagnostic of Risk in Hospitalized Patients Using Machine Learning NCT05893420	AgileMD, Inc.	N/A
Completed	Validation of the Accuracy of a Novel POCT Dry Blood Gas Analyzer in Acute Care Settings NCT06726473	Zhujiang Hospital	—
Recruiting	Drainage Of Pleural Effusions in the Intensive Care Unit (DOPE-ICU) - Feasibility Trial NCT06709456	Olav Schjørring	N/A
Not Yet Recruiting	Positive Expiratory Pressure (PEP) and Continuous High-frequency Oscillation (CHFO) on Lung RECRUITment Using NCT06689020	University of Genova	—
Not Yet Recruiting	MRG-001 as an Immunoregulatory and Regenerative Therapy for ARDS Patients NCT06308926	MedRegen LLC	Phase 2
Not Yet Recruiting	Comparison of Several Oxygenation Targets With Different Oxygen Interfaces - Impact on Oxygen Flow Rates NCT06646991	Laval University	N/A
Active Not Recruiting	Assessment of Organ Failure Risk Predictions in ICU NCT06814327	ETH Zurich	—
Completed	Double Triggering Asynchrony in Mechanically Ventilated Patients. NCT07380607	Mansoura University	—
Recruiting	Routine vs On-demand ECMO for Lung Transplantation NCT06615492	Centre hospitalier de l'Université de Montréal (CHUM)	N/A
Recruiting	Retrospective Cohort Study of Low-Flow Extracorporeal Carbon Dioxide Removal (ECCO2R) System: Evaluating ECCO2 NCT07161271	Hong Kong University	—
Recruiting	Personalized Ultrasound-Guided External Diaphragm Pacing to Improve Outcomes in Invasive Mechanically Ventilat NCT06609577	Daishan Jiang	N/A
Recruiting	Prone Position Assessed by 3D EIT NCT07083973	Peking Union Medical College Hospital	—
Not Yet Recruiting	Comparison of Ventilator Versus Traditional Measurement Methods of Rapid Shallow Breathing Index for Predictin NCT06617156	National Taiwan University Hospital	—
Recruiting	The Effect of phoSPHocreatine on mEdical Emergency Team (Met) tREated Patients NCT06503016	Università Vita-Salute San Raffaele	Phase 3
Not Yet Recruiting	Multi-Disciplinary Treatment on the Anthropomorphism of Large Language Models NCT06627985	North Sichuan Medical College	—
Enrolling By Invitation	Ventilator Mode and Respiratory Physiology NCT06624254	University of California, San Diego	—
Recruiting	Low and High Flow Suctioning in Intubated Infants NCT06443970	Columbia University	N/A
Recruiting	Optimizing Care in Critically Ill at UCHealth by Liberalizing the Target O2 in Mechanically-ventilated ICU Pat NCT06501118	University of Colorado, Denver	N/A
Unknown	High Flow Oxygen Therapy in Patients Undergoing Bronchoscopy Under Sedation NCT04728412	Cardarelli Hospital	N/A
Recruiting	End-Tidal Oxygen for Intubation in the Emergency Department NCT06578468	Sydney Local Health District	N/A
Recruiting	Preventing Cardiovascular Collapse With Vasopressors During Tracheal Intubation NCT05014581	University of Turin, Italy	Phase 3
Recruiting	Effects of PBMT-sMF in Mechanically Ventilated Patients NCT06454006	University of Nove de Julho	N/A
Completed	Effects of L-arginine and Liposomial Vitamin C on Severe Copd Patients Undergoing Pulmonary Rehabilitation. NCT06439875	Istituti Clinici Scientifici Maugeri SpA	N/A
Withdrawn	Concomitant Bedside Percutaneous Tracheostomy and Ultrasound Gastrostomy NCT05955534	University of Maryland, Baltimore	N/A
Recruiting	Precision Ventilation vs Standard Care for Acute Respiratory Distress Syndrome NCT06066502	Beth Israel Deaconess Medical Center	Phase 3
Recruiting	Comparison of Pulse Oximetry (SpO2) With Different Oximeters and Arterial Saturation (SaO2): Oxygap2 Study NCT06102499	Laval University	—
Active Not Recruiting	Respiratory Knowledge Portal Computer and Phone Application to Improve Quality of Mechanical Ventilation by Re NCT06737432	The University of Texas Medical Branch, Galveston	N/A
Recruiting	Improving Psychological Outcomes for Acute Respiratory Failure Survivors Using a Self-Management Intervention NCT06341972	Johns Hopkins University	N/A
Recruiting	Patient-Ventilator Dyssynchrony Detection With a Machine Learning Algorithm NCT06506123	University of Sao Paulo General Hospital	—
Not Yet Recruiting	Integrated Pulmonary Index as a Predictor of Respiratory Compromise in Critically Ill Patients NCT06395532	Ain Shams University	—
Recruiting	The Impact and Effect of Traditional Chinese Medicine Treatment on Organ Failure in Critically Ill Patients NCT06452966	China Medical University Hospital	N/A
Recruiting	A Post Market Surveillance Study of the Hemovent Extracorporeal Cardiopulmonary Support System:The MOBYBOX Tri NCT04183660	Hemovent GmbH	—
Recruiting	High Flow Oxygen Therapy After Spinal Cord Injury NCT06244160	Cardiff and Vale University Health Board	N/A
Recruiting	PRactice of VENTilation in Critically Ill PEDiatric Patients NCT06220825	University Medical Center Groningen	—
Recruiting	Closed-Loop O2 Use During High Flow Oxygen Treatment of Critical Care Adult Patients (CLOUDHFOT) NCT06374589	Başakşehir Çam & Sakura City Hospital	N/A
Completed	Cardiopulmonary Bypass on Mechanical Power and Postoperative Pulmonary Complications NCT06292767	TC Erciyes University	—
Unknown	Oxygenation Efficacy of "Intrinseque Health" Non-Rebreathing Mask ("IHNRM") NCT06310629	China Medical University Hospital	N/A
Completed	Comparison of Gas Exchange Between Two Invasive Mechanical Ventilation Modes in Children NCT05843123	University Children's Hospital, Zurich	Phase 4
Unknown	The Effect of Aromatherapy Massage on Sleep Quality NCT06295900	Nilgün Erdoğan	N/A
Completed	Early Prone Positioning and Clinical Outcomes in Non-Intubated Acute Respiratory Distress Syndrome (ARDS) Pati NCT07133022	Loai Muawiah Zabin	N/A
Recruiting	PEEP Titration and Lung Recruitment Potential Assessed by 3D EIT NCT06594601	Peking Union Medical College Hospital	—
Recruiting	The Efficacy of P0.1-guided Sedation Protocol in Critically Ill Patients Receiving Invasive Mechanical Ventila NCT06203405	Siriraj Hospital	N/A
Recruiting	The Effect of an Additional Pre-extubational Loading Dose of Caffeine-citrate NCT06401083	Semmelweis University	Phase 4
Completed	Utility of Defining ARDS and Past and Current Definitions of ARDS NCT06159465	NMC Specialty Hospital	—
Completed	VitalThings Guardian Contactless Monitoring NCT06083272	VitalThings	—
Unknown	Optimal Timing and Failure Prediction of High Flow Nasal Cannula Oxygen Therapy in Emergency Department: Prosp NCT06064409	Yonsei University	—
Completed	Solid State vs. Balloon Esophageal Catheter for Estimation of Pleural Pressure NCT05817968	Erasmus Medical Center	N/A
Active Not Recruiting	Feasibility of the Comfort Measures Only Time Out (CMOT) NCT05861323	Beth Israel Deaconess Medical Center	N/A
Completed	Impact of Cannulation Strategy on Neurologic Injury in Infants With Respiratory Failure NCT06079034	University of Michigan	—
Recruiting	Respiratory Mechanics Assessment at Different Head of the Bed Elevations in Mechanically Ventilated Patients NCT06409897	University of Sao Paulo General Hospital	N/A
Recruiting	The Family Perspectives Project Pilot Trial NCT06039501	Matthew Modes	N/A
Not Yet Recruiting	High Flow Nasal Cannula Versus Non Invasive Positive Pressure Ventilation in Reducing The Rate of Reintubation NCT06029699	Assiut University	N/A
Unknown	Monitoring of Breathing Effort Through Pressure Time Product Measurement Using Airway Occlusion Pressure NCT06040138	Hospital Italiano de Buenos Aires	—
Recruiting	High-flow Nasal Oxygenation for Apnoeic Oxygenation During Intubation of the Critically Ill NCT05883137	Region Stockholm	—
Completed	CPAP Therapy Through a Helmet or a Full Face Mask in Patients With Acute Hypoxemic Respiratory Failure: Cross- NCT06113432	I.M. Sechenov First Moscow State Medical University	N/A
Completed	Definition and Management of Right Ventricular Injury in Adult Patients Receiving Extracorporeal Membrane Oxyg NCT05948332	Prashant Nasa	—
Completed	Investigation of Respiratory Muscle Strength, Exercise Capacity, Physical Activity and Sleep Quality Level in NCT06008470	Kırıkkale University	—
Completed	HFNC vs. NIV in Acute COPD Exacerbations NCT06495086	Haseki Training and Research Hospital	N/A
Unknown	POCUS and Respiratory Failure Prognosis Based on Diaphragmatic Dysfunction NCT05869045	Azienda Ospedaliero-Universitaria di Modena	—
Unknown	Construction of Early Warning Model for Pulmonary Complications Risk of Surgical Patients Based on Multimodal NCT06057688	Renrong Gong	—
Completed	Inspiratory Effort at Different Expiratory Cycling and Airway Resistance During Pressure Support Ventilation ( NCT05952726	Fondazione IRCCS San Gerardo dei Tintori	N/A
Active Not Recruiting	The State of Nebulizer Therapy in Russian Federation NCT05617079	Russian Federation of Anesthesiologists and Reanimatologists	—
Unknown	Lung Overdistension and Abdominal Pressure Rise NCT06174636	University of Padova	N/A
Completed	Pectointercostal Fascial Plane Block (PIFB) Alone Versus PIFB With Rectus Sheath Block (RSB) in Cardiac Surger NCT04908449	Medical College of Wisconsin	Phase 1
Recruiting	HYPoxaEmic Respiratory Failure and Awake Prone Ventilation NCT05990101	Vilnius University	N/A
Active Not Recruiting	Safety and Performance of NivolisMonitor and NivolisAnton for Monitoring Patients on Ventilatory Assistance at NCT05698602	VIVARDIS	N/A
Completed	Cuff Leak Test and Airway Obstruction in Mechanically Ventilated ICU Patients NCT05456542	St. Joseph's Healthcare Hamilton	Phase 3
Unknown	HVNI for Successful Weaning in Respiratory Failure NCT05855213	Alexandria University	N/A
Recruiting	Analgesia-First Sedation in Trauma Patients NCT05751863	MemorialCare Health System	N/A
Withdrawn	Comparison of Esophageal Manometry and CT Scan Measurements NCT04213911	Massachusetts General Hospital	—
Recruiting	Hospital Airway Resuscitation Trial NCT05520762	Montefiore Medical Center	N/A
Unknown	Sivelestat for Acute Respiratory Distress Syndrome Due to COVID-19 NCT05697016	Beijing Tiantan Hospital	N/A
Completed	Closed-Loop O2 Use During Invasive Mechanical Ventilation Of Pediatric Patients NCT05714527	Dr. Behcet Uz Children's Hospital	N/A
Recruiting	Effects of High-flow Oxygen Therapy and Non-invasive Ventilation on Lung Volumes and on Upper Airway NCT05643911	University Hospital, Montpellier	N/A
Unknown	Doppler Ultrasound Renal Arterial Resistive Indices As Predictor Of Multiorgan Failure In Patients With Acute NCT03897920	University of Modena and Reggio Emilia	—
Completed	Re- Admission Rate Among Survived Patients With Acute Respiratory Failure NCT06291636	Mansoura University	—
Unknown	NIV-FOB, HFNC-FOB- Comparison of Methods NCT05655026	Medical University of Silesia	N/A
Completed	Multicenter, Multinational, Follow-Up Clinical Trial of the Performance of RESPINOR DXT to Identify Patients a NCT05580185	Respinor AS	—
Unknown	Different Approaches of Spinal Anesthesia in Patients Undergoing Cesarean Section NCT05637645	Bahawal Victoria Hospital Bahawalpur	N/A
Recruiting	Comparison of Two Oxygenation Targets With Two Different Oximeters - Impact on Oxygen Flow Rates and Oxygenati NCT05590130	Laval University	N/A
Completed	Mode Of Ventilation During Critical IllnEss Pilot Trial NCT05563779	Vanderbilt University Medical Center	N/A
Recruiting	Diaphragm Atrophy and Dysfunction in Mechanical Ventilation NCT05211661	RWTH Aachen University	—
Completed	Effect of HFNO Therapy on Respiratory Effort After Extubation NCT05652699	Henrik Endeman	N/A
Completed	Recruitment Manoeuvres in Critically Ill Patients NCT05508724	University of Oxford	—
Recruiting	Change in the Phase III Slope of the Volumetric Capnography by Prone Positioning in Acute Respiratory Distress NCT05535543	Istanbul University - Cerrahpasa	—
Completed	Muscle Pressure Estimation With Artificial Intelligence During Mechanical Ventilation NCT05820347	University of Sao Paulo General Hospital	N/A
Completed	Using Vasopressor Medication to Support Blood Pressure During Intubation Procedure NCT05355974	Wright State University	Phase 3
Unknown	Clinical Evaluation of EZVent in Hospitalized Mechanically Ventilated Patients NCT05399017	Triclinium Clinical Development Middle East and North Africa	N/A
Withdrawn	Repeated Measures Trial of Temporary Automated Manual Ventilation Versus Noninvasive Oxygenation or Convention NCT04369274	Massachusetts General Hospital	N/A
Completed	CONFOCAL-2 Interventional Pilot Study NCT07296029	Queen's University	Phase 1 / Phase 2
Enrolling By Invitation	Distribution of Ventilation, Respiratory Drive and Gas Exchange: Measurements and Monitoring NCT05462600	University of California, San Diego	—
Recruiting	Estimation of the Diaphragm Electrical Activity and Intercostal Thickening Fraction During Different Pattern o NCT05990348	Fondazione Policlinico Universitario Agostino Gemelli IRCCS	—
Unknown	Safety and Usability of the LUMENA Non-invasive Ventilation Mask NCT05479773	Inspir Labs Ltd.	N/A
Completed	Time Course of Neuro-ventilatory Efficiency During a Spontaneous Breathing Training NCT05380687	University Hospital, Antwerp	N/A
Completed	Cuff Pressure Control and Evacuation of Subglottic Secretions To Prevent Pneumonia NCT05403320	Fondazione Policlinico Universitario Agostino Gemelli IRCCS	N/A
Completed	High-dose L-Carnitine and Diaphragmatic Function Assessed by Ultrasonography in Patients With Respiratory Fail NCT05322447	Ain Shams University	Phase 4
Recruiting	Transpulmonary Pressure Guided Mechanical Ventilation Weaning in Obesity NCT05530434	University of Mississippi Medical Center	N/A
Completed	Pattern of Admission and Outcome of Patients Admitted to the Intensive Care NCT05591209	Haramaya Unversity	—
Unknown	Individualization Flow in Patients Treated With High Flow Nasal Therapy (iFLOW) NCT05401474	Hospital Universitari Vall d'Hebron Research Institute	N/A
Unknown	Volume Mode Non-invasive Ventilation in Amyotrophic Lateral Sclerosis NCT05328492	University Hospitals Coventry and Warwickshire NHS Trust	N/A
Recruiting	Helmet NIV vs. CPAP vs. High-flow Nasal Oxygen in Hypoxemic Respiratory Failure NCT05089695	Fondazione Policlinico Universitario Agostino Gemelli IRCCS	N/A
Unknown	CPAP Versus HFNO for the Treatment of Acute Hypoxemic Respiratory Failure Due to Community Acquired Pneumonia NCT05755425	Evangelismos Hospital	—
Completed	The Use of Vibrational Methods of Influencing the Lungs to Restore Their Functional State NCT05159401	Petrovsky National Research Centre of Surgery	N/A
Completed	RASECAL-Bronchoscopic Ambusampler NCT05964075	Chelsea and Westminster NHS Foundation Trust	—
Active Not Recruiting	the Inhaled β2-adrenergic Receptor Agonist for Transient Tachypnoea of the Newborn (the REFSAL Trial) NCT05527704	Medical University of Warsaw	Phase 3
Unknown	Angiotensin-(1,7) Treatment in COVID-19: the ATCO Trial NCT04332666	Erasme University Hospital	Phase 2 / Phase 3
Completed	HEAVEN Criteria: Prediction of Difficult Airway for In- Hospital Emergency Airway Management NCT04764799	Thomas Riva	—
Unknown	NIV Mask Assessment of Usability and Performance NCT05059288	Fisher and Paykel Healthcare	N/A
Completed	Acetaminophen and Ascorbate in Sepsis: Targeted Therapy to Enhance Recovery NCT04291508	Massachusetts General Hospital	Phase 2
Completed	Gas Exchange Derangement Physiopathology in Critically Ill Patients With COVID-19 NCT05132933	Policlinico Hospital	N/A
Completed	Closed-loop FiO2 Controller During High Flow Oxygen Treatment In Pediatric Patients (COFICOHFOT) NCT05032365	Dr. Behcet Uz Children's Hospital	N/A
Withdrawn	Comparing Post Cardiac Surgery Outcomes in ESRD Patient's With Early Dialysis Versus Standard Care NCT04705701	Northwell Health	N/A
Completed	Ventilation and Perfusion in the Respiratory System NCT05081895	University of California, San Diego	—
Completed	Threshold Inspiratory Trainer Versus Trigger Sensitivity Adjustment on Weaning From Mechanical Ventilation NCT05846945	Cairo University	N/A
Unknown	A Pilot Study Investigating the Detection of Episodes of Severe Patient-Ventilator Asynchrony NCT04550871	Autonomous Healthcare, Inc.	—
Unknown	A Retrospective Study to Evaluate the Predictability of Abnormal Arterial Blood Gas Measurements Through Novel NCT05384314	Beaumont Hospital	—
Completed	Safety and Efficacy of Argatroban Applicated in Anticoagulation of V-V ECMO NCT04925167	Beijing Chao Yang Hospital	N/A
Unknown	Comparative Evaluation of the McGrath Videolaryngoscope and the Direct Laryngoscopy for Tracheal Intubation in NCT04930419	Assistance Publique - Hôpitaux de Paris	Phase 3
Unknown	The Effectiveness of Respiratory Tele-rehabilitation After COVID-19 Pneumonia Related: a Randomized Controlled NCT05007457	IRCCS Azienda Ospedaliero-Universitaria di Bologna	N/A
Completed	Ventilation Weaning Strategies and Correlation to Outcomes in Tracheostomized Patients in the Lausanne ICU NCT04987398	Piquilloud Imboden Lise	—
Recruiting	Bio-Banking of Specimens for Advanced Lung Disease and Lung Transplant Research NCT04664192	Baylor Research Institute	—
Completed	COPD Prognosis in Covid Patients NCT05274490	Sohag University	—
Active Not Recruiting	Apparatus and Method for Moving Patients NCT04882865	Nova Scotia Health Authority	—
Completed	Multicenter, Multinational, Clinical Trial of the Performance of RESPINOR DXT to Identify Patients at Increase NCT04696406	Respinor AS	—
Unknown	Effects of NIV and CPAP on Ventilation Distribution, Measured by EIT, During Deep Sedation in Paediatric Patie NCT05495477	Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico	N/A
Terminated	Furosemide as Supportive Therapy for COVID-19 Respiratory Failure NCT04588792	Dr. John Muscedere	Phase 2 / Phase 3
Withdrawn	Effects of mTOR Inhibition With Sirolimus (RAPA) in Patients With COVID-19 to Moderate the Progression of ARDS NCT04482712	The University of Texas Health Science Center at San Antonio	Phase 1 / Phase 2
Terminated	Providing Optimal PEEP During Mechanical Ventilation for Obese Patients Using Esophageal Balloon NCT03951064	University of North Carolina, Chapel Hill	N/A
Recruiting	OxyGap : Comparison Between Different Pulse Oximeter and With the Arterial Blood Gase NCT04772183	Laval University	—
Completed	Assessment of Breathing Using an Under-bed Weighing Scale NCT04736212	Beth Israel Deaconess Medical Center	—
Completed	Comparison of Non-invasive Methods of Lung Ventilation in Patients With Respiratory Failure After Cardiac Surg NCT04787666	Petrovsky National Research Centre of Surgery	N/A
Terminated	Mask Adhesive Institutional Study NCT04644276	Philips Clinical & Medical Affairs Global	N/A
Completed	Diaphragmatic Echography in COVID-19 Pneumonia NCT05805579	Javier Lázaro	—
Completed	Immunologic Features of Respiratory Failure in Pediatric Hematopoietic Cell Transplantation (HCT) Recipients a NCT04355780	St. Jude Children's Research Hospital	—
Completed	Efficacy of HFNC Combined With Sequential NIV in Patients With COPD Complicated With Type II Respiratory Failu NCT06992479	Beijing YouAn Hospital	N/A
Completed	Comparing Two Different Modes of Ventilation in Pretem Neonates Bilevel VG and PRVC NCT04191239	Ankara City Hospital Bilkent	—
Completed	COVID-19 Vaccination AZV 2021-2023 NCT05589233	University Hospital Hradec Kralove	—
Terminated	RENOVATE Palliative: HFNC vs. Standard Respiratory Support in Patients With Do-Not-Intubate Order and ARF NCT04269681	Hospital do Coracao	N/A
Completed	Fluid Overload and Pulmonary Function NCT05129930	Pirogov Russian National Research Medical University	—
Unknown	EX-PO Trial : Evaluation of the Occlusion Pressure (PO.1) in Extubation Failure NCT04654273	Poitiers University Hospital	—
Unknown	Plasma Exchange (PLEX) and Convalescent Plasma (CCP) in COVID-19 Patients With Multiorgan Failure NCT04634422	Wladimir Szpirt	N/A
Completed	Nebulised Heparin in Patients With Severe COVID-19 NCT04545541	Australian National University	Phase 2 / Phase 3
Completed	Patient-ventilator Interaction During NIV With Helmet: a Comparison Between PSV and the New NIV NPS Software NCT06004206	ASL Novara	N/A
Completed	Ventilator-associated Injury (VAI) in Chronic Home Mechanical Ventilation NCT04521426	University Medical Center Groningen	—
Completed	Reduced Anticoagulation Targets in ECLS (RATE) NCT04536272	University Medical Center Groningen	Phase 3
Completed	Photoplethysmographic Scaling of Dyspnoea NCT04582838	Institutul de Urgenţă pentru Boli Cardiovasculare Prof.Dr. C.C. Iliescu	—
Unknown	COVID-19 Advanced Respiratory Physiology (CARP) Study NCT04668313	NHS Greater Glasgow and Clyde	—
Completed	Real Time Evaluation of Dynamic Changes of the Lungs During Respiratory Support of VLBW Neonates Using EIT NCT04542096	Vilnius University	—
Completed	Tenecteplase in Patients With COVID-19 NCT04505592	Hooman Poor	Phase 2
Completed	The Emergency Department Sedation Pilot Trial NCT04410783	Washington University School of Medicine	N/A
Completed	Efficacy of CONvalescent Plasma in Patients With COVID-19 Treated With Mechanical Ventilation NCT04558476	University of Liege	Phase 2
Completed	Nasal Oxygen Therapy After Cardiac Surgery NCT05308719	Papworth Hospital NHS Foundation Trust	N/A
Unknown	Absent Visitors: The Wider Implications of COVID-19 on Non-COVID Cardiothoracic ICU Patients, Relatives and St NCT04538469	University of Glasgow	—
Completed	Impact of Extubation Location After Surgery on Perioperative Times NCT06249659	University Hospital, Clermont-Ferrand	—
Suspended	Cytokine Adsorption in Patients With Severe COVID-19 Pneumonia Requiring Extracorporeal Membrane Oxygenation NCT04385771	Dr. Alexander Supady	N/A
Completed	Use of Angiotensin-(1-7) in COVID-19 NCT04633772	Erasme University Hospital	Phase 1 / Phase 2
Completed	The Physiologic Effect of the Flow Generated by High Flow Nasal Cannula in Mild Respiratory Failure NCT05708287	Hadassah Medical Organization	N/A
Unknown	High Flow Nasal Cannula Oxygen During Sedation for Video-assisted Thoracoscopic Surgery NCT04520568	Alexandria University	Phase 2
Completed	Identifying and Understanding Risk Factors for Instability and Adverse Events Associated With Chest Physiother NCT04146753	Great Ormond Street Hospital for Children NHS Foundation Trust	—
Terminated	Pemziviptadil (PB1046), a Long-acting, Sustained Release Human VIP Analogue, Intended to Provide Clinical Impr NCT04433546	PhaseBio Pharmaceuticals Inc.	Phase 2
Completed	Prone Position for Nonintubated Patients With COVID-19 and Hypoxemic Respiratory Failure NCT04641182	Pontificia Universidad Catolica de Chile	—
Completed	Exercise Capacity Under Various FiO2 and Oxygen Flow Rates Using HFNC NCT04471220	National Hospital Organization Minami Kyoto Hospital	N/A
Completed	Stress Related Disorders in Family Members of COVID-19 Patients Admitted to the ICU NCT04476914	University of Colorado, Denver	—
Completed	Infusion of Prostacyclin (Iloprost) vs Placebo for 72-hours in COVID-19 Patients With Respiratory Failure NCT04420741	Pär Johansson	Phase 2
Completed	Awake-Prone Positioning Strategy for Hypoxic Patients With COVID-19 NCT04547283	Wake Forest University Health Sciences	N/A
Completed	HFNC and NIV for COVID-19 Complicated by Respiratory Failure NCT04452708	Chinese University of Hong Kong	—
Completed	Proning Early in Awake COVID-19 Hypoxic Respiratory Failure (PREACHR) Study NCT05130541	New York Hospital Queens	N/A
Completed	Comparative Study of Anaconda System Use Versus Conventional Sedation in COVID-19 Patients. NCT06208592	Hospital Español de Mexico	—
Completed	Plasma Adsorption in Patients With Confirmed COVID-19 NCT04358003	Marker Therapeutics AG	N/A
Completed	Photobiomodulation Therapy Combined With Static Magnetic Field in Patients With COVID-19 NCT04386694	University of Nove de Julho	N/A
Terminated	Study Assessing Vagus Nerve Stimulation in CoViD-19 Respiratory Symptoms NCT04382391	Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)	N/A
Completed	COVid-19: Awake Proning and High-flow Nasal Cannula in respiratorY DistrEss NCT04395144	Hôpital de Verdun	N/A
Completed	Fibrinolytic Therapy to Treat ARDS in the Setting of COVID-19 Infection NCT04357730	Denver Health and Hospital Authority	Phase 2
Terminated	Azithromycin Added to Hydrochloroquine in Patients Admitted to Intensive Care With COVID-19: Randomised Contro NCT04339816	Frantisek Duska, MD, PhD	Phase 3
Completed	One Year Follow-ups of Patients Admitted to Spanish Intensive Care Units Due to COVID-19 NCT04457505	Consorcio Centro de Investigación Biomédica en Red (CIBER)	—
Unknown	Effects of Cardiovascular and Pulmonary Optimization on Cerebral Oxygenation in COVID-19 Patients With Severe NCT04392089	Hvidovre University Hospital	—
Terminated	Prone Positioning in Awake Patients With COVID-19 Requiring Hospitalization NCT04368000	University of Utah	N/A
Completed	Prognostic Value of Point of Care Cardiac and Lung Ultrasound in COVID-19 NCT04379544	University of Pennsylvania	—
Withdrawn	Use of Dexmedetomidine in Light to Moderate Sedation in the Patient in the Palliative Situation of a Sars-cov- NCT04350086	University Hospital, Limoges	Phase 4
Unknown	Peer Support for Post Intensive Care Syndrome Self-Management NCT03788096	University of Texas at Austin	N/A
Completed	Characteristics and Outcomes of Patients With COVID-19 Treated With HFNO and Prone Positioning NCT05178212	Hospital Privado de Comunidad de Mar del Plata	—
Terminated	Non-Invasive Monitoring of Respiratory Function in Spontaneously Breathing Patients With COVID-19 Infection NCT04356443	Massachusetts General Hospital	—
Completed	Awake Prone Position to Reduce Ventilation Inhomogeneity in COVID-19 Acute Respiratory Failure NCT04632602	Assistance Publique Hopitaux De Marseille	N/A
Unknown	Biomarkers, Genomics, Physiology in Critically Ill and ECMO Patients NCT04669444	University of California, San Diego	N/A
Active Not Recruiting	Long Term Outcomes of Patients With COVID-19 NCT04360538	University of Chicago	—
Completed	A Study of the Effectiveness of an Off Label Mefloquine Use for the Treatment of Patients With COVID19 NCT04347031	Burnasyan Federal Medical Biophysical Center	Phase 2 / Phase 3
Completed	Enhanced Platelet Inhibition in Critically Ill Patients With COVID-19 NCT04368377	University of Milan	Phase 2
Completed	Compartmental Inflammation in Mechanically Ventilated Patients With COVID-19 NCT04354584	Hvidovre University Hospital	—
Unknown	NIV and CPAP Failure Predictors in COVID-19 Associated Respiratory Failure NCT04342104	Hospital General Universitario Morales Meseguer	—
Completed	Cytokine Adsorption in Severe COVID-19 Pneumonia Requiring Extracorporeal Membrane Oxygenation NCT04324528	Dr. Alexander Supady	N/A
Completed	Clinical Characteristics and Outcomes of Patients With COVID-19 on Mechanical Ventilation in Argentina NCT04611269	Argentinian Intensive Care Society	—
Unknown	Acute Respiratory Failure and COVID-19 in Real Life NCT04307459	University of Milan	—
Completed	Use of Oxygen Hoods in Patients Failing on Conventional High-flow Oxygen Delivery Systems, Effects on Oxygenat NCT04407260	Northwell Health	—
Completed	Postoperative Remote Monitoring of Vital Signs in Older Cardiac Surgery Patients NCT03944967	St. Antonius Hospital	—
Completed	COVID-19 in Liver Transplant Recipients NCT04361591	Hospital Clinic of Barcelona	—
Completed	Safety and Feasibility of Percutaneous Dilatational Tracheostomy in Patients With Severe COVID-19 Supported by NCT05045885	Hamad Medical Corporation	—
Unknown	High Flow Nasal Cannula in Thoracic Surgery: a Physiologic Study NCT03877172	Hospital Clinic of Barcelona	N/A
Completed	Incidence, Risk Factors and Outcomes of Diaphragm Dysfunction After Lung Transplantation NCT04103996	University Health Network, Toronto	—
Completed	Blunt Thoracic Trauma: Definition of a Standard Operating Procedure NCT05617404	Corporacion Parc Tauli	—
Completed	International Study of Inflammation in COVID-19 NCT04818866	University of Michigan	—
Completed	High-flow Nasal Cannula vs. Helmet PSV vs. Helmet CPAP During Respiratory Failure NCT04241861	Fondazione Policlinico Universitario Agostino Gemelli IRCCS	N/A
Unknown	'Single Hand Used inTubaTing Laryngoscope Evaluation' Study NCT04310384	University of the Basque Country (UPV/EHU)	N/A
Terminated	Multidisciplinary Mobile Unit for Preventing Hospitalization of Nursing Home Residents NCT04085679	Azienda Ospedaliero-Universitaria di Parma	—
Unknown	Jet or Vibrating Mesh Nebulisation for Secretion Management in ICU NCT05635903	NHS Greater Glasgow and Clyde	N/A
Unknown	Investigating Health Related Quality of Life in Patients With Chronic Respiratory Failure NCT04236726	Guy's and St Thomas' NHS Foundation Trust	—
Terminated	DAMP-Mediated Innate Immune Failure and Pneumonia After Trauma - the Harvard-Longwood (HALO) Campus Area Conso NCT03993002	Beth Israel Deaconess Medical Center	N/A
Completed	Critical Respiratory Diseases in Ex-preterm Infants in PICU NCT04284891	National Children's Hospital, Vietnam	—
Completed	High-Flow Nasal Oxygen Cannula Compared to Non-Invasive Ventilation in Adult Patients With AcuTE Respiratory F NCT03643939	Hospital do Coracao	N/A
Completed	Automated Oxygen Titration During Walking in Patients With COPD NCT04123730	Hvidovre University Hospital	N/A
Completed	Automated Oxygen Control by O2matic to Patients Admitted With Acute Hypoxemia NCT04079465	Hvidovre University Hospital	N/A
Completed	Early Non-invasive Ventilation and High-flow Nasal Oxygen Therapy for Preventing Delayed Respiratory Failure i NCT03943914	University Hospital, Bordeaux	N/A
Unknown	Rapid Atrial Fibrillation Treatment Strategy NCT04092621	Our Lady of the Lake Hospital	Phase 4
Completed	Pragmatic Investigation of Volume Targeted Ventilation-1 NCT03909854	Wake Forest University Health Sciences	N/A
Unknown	Postoperative Respiratory Abnormalities NCT04079829	Efficacy Care R&D Ltd	—
Completed	Analysis of Endotoxin Activity in Patients With ECMO NCT03978728	National Taiwan University Hospital	—
Unknown	Clinical Assessment Method in Patients Using Non-invasive Ventilation NCT04053777	The First Affiliated Hospital of Guangzhou Medical University	—
Terminated	Avoiding Neuromuscular Blockers to Reduce Complications NCT03962725	Beth Israel Deaconess Medical Center	Phase 4
Unknown	Delirium, Agitation/Sedation, Pain and Dyspnea in Respiratory Intensive Care Unit (NIVILIUM) NCT03880084	University of Modena and Reggio Emilia	—
Completed	Effect of Time Delay and Syringe Surface Area on Blood Gas Samples Analysis NCT06522009	Helwan University	—
Completed	Comparison Between Limited Driving Pressure Ventilation and Conventional Mechanical Ventilation Strategies in NCT04035915	Mahidol University	N/A
Unknown	Predictability of Echographic Excursion of the Diaphragm for Intubation in COPD- Patients With Acute Respirato NCT04591509	European Georges Pompidou Hospital	—
Unknown	RIB PAIN (Rib Fractures Treated With Parental Analgesia With Infused LidocaiNe) NCT03770208	Western University, Canada	N/A
Suspended	Diaphragm Ultrasound as a Powerful Tool in Managing Acute Hypoxemic Respiratory Failure in Hematological Patie NCT04026217	Azienda Sanitaria-Universitaria Integrata di Udine	—
Completed	Phrenic Nerve Block to Mitigate Self-inflicted Lung Injury NCT03978845	University of Sao Paulo General Hospital	N/A
Completed	Parathyroid Hormone Kinetics During CRRT NCT03873675	Uniwersytecki Szpital Kliniczny w Opolu	—
Completed	Evaluation of the Effectiveness of Vibroacoustic Therapy in the Complex Treatment of Acute Respiratory Failure NCT03911947	Astana Medical University	N/A
Unknown	High Flow Nasal Cannula Versus Non-invasive Ventilation in Prevention of Escalation to Invasive Mechanical Ven NCT03788304	Assiut University	N/A
Recruiting	Recovery From ICUAW Following Severe Respiratory and Cardiac Failure NCT03753412	Barts & The London NHS Trust	—
Terminated	Nasal High-frequency Jet Ventilation (nHFJV) Following Extubation in Preterm Infants NCT03558737	University of Utah	N/A
Recruiting	Diaphragm Structure and Pathobiology in Patients Being Bridged to Lung Transplant NCT03667027	University Health Network, Toronto	—
Terminated	Safety of Optimal PEEP in NSICU Patients NCT03862027	University of North Carolina, Chapel Hill	N/A
Unknown	Correlations Among Functional Performance, Muscle Strength and Weaning Rate in Mechanically Ventilated Patient NCT03894293	Taipei Veterans General Hospital, Taiwan	—
Terminated	Pan-genotypic Direct Acting Antiviral Therapy in Donor HCV-positive to Recipient HCV-negative Lung Transplant NCT03625687	Massachusetts General Hospital	Phase 4
Unknown	Assessments of Diaphragm-pleural Mechanics During the Weaning From Prolonged Mechanical Ventilation NCT03842280	National Taiwan University Hospital	—
Completed	Metabolites of Tramadol in the Postoperative Surgical Patients NCT04004481	Osijek University Hospital	—
Completed	Effectiveness of Music Intervention on Anxiety and Physiological Responses in Critical Ill Patient NCT04977011	Min-Sheng General Hospital	N/A
Completed	Effect of PEEP on Lung Regional Ventilation and Perfusion NCT04081155	Yun Long	—
Unknown	Ventilator Induced Diaphragm Dysfunction in Pediatric Critically Ill Patients (VIDD) NCT03768232	Bambino Gesù Hospital and Research Institute	—
Completed	Pilot Simulation RCT of Telemedical Support for Paramedics NCT03742167	Boston Medical Center	N/A
Completed	Healthcare Renunciation in Respiratory Chronic Disease and Treatment Compliance (OBSERVE) NCT03591250	University Hospital, Grenoble	—
Completed	Use of Lung Ultrasound to Diagnose the Etiology of Respiratory Failure in a PICU. NCT03744169	University of Wisconsin, Madison	—
Completed	Oxygen Control and Weaning by O2matic to Patients Admitted With an Exacerbation of COPD NCT03661086	Hvidovre University Hospital	N/A
Completed	Esophageal Balloon Calibration in Assisted Ventilation Mode NCT03721237	Azienda Ospedaliero Universitaria Maggiore della Carita	N/A
Unknown	Education and Training Competences in Thoracic Ultrasound NCT03728491	Odense University Hospital	N/A
Unknown	Hospital-wide Incidence, Clinical Characteristics and Outcomes of ARDS NCT03546699	University Health Network, Toronto	—
Active Not Recruiting	CYCLE: A Randomized Clinical Trial of Early In-bed Cycling for Mechanically Ventilated Patients NCT03471247	McMaster University	N/A
Terminated	Identifying Novel Aging Targets for Treatment of Delirium NCT03682874	Wake Forest University Health Sciences	—
Active Not Recruiting	Veno-venous Extracorporeal Membrane Oxygenation (VV-ECMO) Heparin Study NCT04496362	Baylor Research Institute	Phase 4
Completed	International Observational Study on Airway Management in Critically Ill Patients NCT03616054	Azienda Ospedaliera San Gerardo di Monza	—
Unknown	The Impact of Age-dependent Haptoglobin Deficiency on Plasma Free Hemoglobin Levels During Extracorporeal Memb NCT03472768	University of Colorado, Denver	—
Completed	Indirect Calorimetry Usage and Effect in Ventilator-free Days and Muscle Thickness in Septic Ventilated Patien NCT03440593	Baylor Research Institute	N/A
Unknown	HOPE (Home-based Oxygen [Portable] and Exercise) for Patients on Long Term Oxygen Therapy (LTOT) NCT03662438	Singapore General Hospital	N/A
Completed	Evaluating Safety and Efficacy of Umbulizer in Patients Requiring Intermittent Positive Pressure Ventilation NCT04030208	Umbulizer LLC	N/A
Terminated	Entrainment-Based Mechanical Ventilation NCT03512067	Brigham and Women's Hospital	N/A
Completed	Respiratory Physiotherapy in Mechanical Ventilation NCT04670939	Muğla Sıtkı Koçman University	N/A
Completed	Pragmatic Investigation of optimaL Oxygen Targets Trial NCT03537937	Vanderbilt University Medical Center	N/A

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