NCT04342104

NIV and CPAP Failure Predictors in COVID-19 Associated Respiratory Failure

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: Hospital General Universitario Morales Meseguer · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Evaluate HACOR socre utility and efficacy in predicting NIV and/or CPAP failure in patients with COVID-19 associated respiratory failure. Propose adaptations to HACOR score based on the "state of art" of COVID-19

Detailed description

Evaluate HACOR socre utility and efficacy in predicting NIV and/or CPAP failure in patients with COVID-19 associated respiratory failure. Propose adaptations to HACOR score based on the "state of art" of COVID-19 \- this adaptations may include radiologic aggravation and monitoring of CRF, ferritin, LDH, d-dimers, NT-proBNP, troponin I, GOT, GPT, blood count

Conditions

• Respiratory Failure
• Covid-19

Interventions

Type	Name	Description
OTHER	Monitoring for aggravation	Monitor patients on CPAP or NIV and analyzing possible variables that may predict failure, namely: * lymphopenia * thrombocytopenia * CRP * ferritin * LDH * troponin I * NT-ProBNP * Liver enzymes * D-dimers * radiologic aggravation " 1 day and 1 week after starting NIV or CPAP
OTHER	Evaluate HACOR score effectivity in this patients	Apply the HACOR score after starting NIV and CPAP and later verify if it was effective in predicting NIV/CPAP failure

Timeline

• Start date: 2020-04-01
• Primary completion: 2020-11-30
• Completion: 2021-11-15
• First posted: 2020-04-10
• Last updated: 2021-08-30

Locations

1 site across 1 country: Spain