NCT05846945

Threshold Inspiratory Trainer Versus Trigger Sensitivity Adjustment on Weaning From Mechanical Ventilation

Effect of Threshold Inspiratory Trainer Versus Trigger Sensitivity Adjustment on Weaning From Mechanical Ventilation

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 90 (actual)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 50 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

Ninety adult patients from both gender, with acute respiratory failure, intubated and mechanically ventilated. Their ages ranged from 50 to 70 years. They were selected from Intensive Care Unit (ICU), Department of Chest Diseases, Cairo University Hospitals. They have randomly assigned into three equal groups. Group (A): trained by threshold IMT device plus routine physical therapy. Group (B): trained by adjusting MV trigger sensitivity plus routine physical therapy. Group (C): only received routine physical therapy. (Negative inspiratory force NIF, arterial blood gases, P/F ration, respiratory rate RR, tidal volume VT, and rapid shallow breathing index RSBI) were measured before the study and at the end of the study (just before weaning for successfully weaned patients, or on the 10 day of intervention for failed weaning patients).

Conditions

• Respiratory Failure

Interventions

Type	Name	Description
OTHER	Threshold inspiratory muscle trainer device	The threshold inspiratory muscle trainer (IMT) device offers resistance to respiration through the spring-loaded valve.
OTHER	Adjusting mechanical ventilator trigger sensitivity	modifying the mechanical ventilator trigger sensitivity so that patients can only initiate inspiratory flow by producing more negative intrathoracic pressure
OTHER	Chest physiotherapy	Conventional chest physiotherapy

Timeline

• Start date: 2021-08-12
• Primary completion: 2022-06-26
• Completion: 2022-07-10
• First posted: 2023-05-06
• Last updated: 2023-05-06

Locations

1 site across 1 country: Egypt