NCT07334457

Study of Platelet Population Changes Under Circulatory Support With ECMO

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 75 (estimated)
• Sponsor: University Hospital, Strasbourg, France · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: —

Summary

Advances in flow cytometry techniques have led to a better understanding of platelet phenotypes and have revealed the existence of four major platelet populations with distinct functional properties (native, proaggregating, procoagulating, or apoptotic). These phenotypes have a significant impact on the hemostatic capacity of blood platelets, and a proportional change in these populations during ECMO treatment could, at least in part, contribute to the observed complications.

Conditions

• Cardiac Failure
• Respiratory Failure

Timeline

• Start date: 2025-03-11
• Primary completion: 2027-03-01
• Completion: 2027-03-11
• First posted: 2026-01-12
• Last updated: 2026-01-12

Locations

1 site across 1 country: France