NCT01587963

High Dose Vitamin C in the Critically Ill Patient

The Efficacy of High Dose Vitamin C in the Critically Ill Patient Population

• Status: Terminated
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 11 (actual)
• Sponsor: Rutgers, The State University of New Jersey · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine the effectiveness of high doses of Vitamin C in critically ill patients.

Detailed description

It has been shown that the stress that occurs during trauma, infection and/or shock depletes many of the body's resources such as Vitamin C (ascorbic acid) which may contribute to further complications. The purpose of this study is to determine the effectiveness of high doses of Vitamin C in critically ill patients.

Conditions

• Shock

Interventions

Type	Name	Description
DRUG	Ascorbic Acid	66mg/kg/hour of peripheral intravenous Vitamin C infusion for 24 hour duration, maximum total of 200 grams
OTHER	Ringers Lactate or Normal Saline	Fluid resuscitation will be given with NS or LR to achieve a same mean urine output of 0.5cc/kg/hour.

Timeline

• Start date: 2013-02-01
• Primary completion: 2014-02-01
• Completion: 2015-04-01
• First posted: 2012-04-30
• Last updated: 2017-05-11
• Results posted: 2017-05-11

Locations

1 site across 1 country: United States