NCT07529990

Impact of Sodium Profiling During Haemodialysis on Haemodynamic Tolerance and Sonographic Extravascular Lung Water in Shocked Patients With Acute Kidney Injury

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 60 (actual)
• Sponsor: Fayoum University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

A study conducted to evaluate the effects of sodium profiling haemodialysis compared with conventional haemodialysis on hemodynamic tolerance and extravascular lung water in critically ill patients with AKI and shock.

Detailed description

A prospective comparative study was conducted on 60 ICU patients with AKI and shock and indicated for acute intermittent hemodialysis, divided into three groups of 20 patients each: Group 1: conventional hemodialysis, Group 2: linear sodium profiling, and Group 3: stepwise sodium profiling. Hemodynamic parameters, vasopressor requirements, lung ultrasound scores, and IVC measurements were assessed before, during, and after dialysis to evaluate the effects of sodium profiling haemodialysis compared with conventional haemodialysis on hemodynamic tolerance and extravascular lung water in critically ill patients with AKI and shock.

Conditions

• Acute Kidney Injury
• Shock

Timeline

• Start date: 2024-01-01
• Primary completion: 2025-06-15
• Completion: 2025-07-05
• First posted: 2026-04-14
• Last updated: 2026-04-14

Locations

1 site across 1 country: Egypt