NCT06930235

Effectiveness of Midodrine as an Adjuvant to Norepinephrine in Weaning Critically Ill Patients From Vasopressors

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 112 (estimated)
• Sponsor: Sohag University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study aims to evaluate the effectiveness of midodrine as an adjuvant to norepinephrine in weaning critically ill patients from vasopressors

Conditions

• Shock

Interventions

Type	Name	Description
DRUG	Weaning critically ill patients from norepinephrine using midodrine as an adjuvant to norepinephrine	• Patients in group I will receive midodrine (10 mg orally every 8 hours) in addition to administered concurrently with ongoing intravenous norepinephrine after being on norepinephrine for more than 24 hrs.
DRUG	Weaning critically ill patients from norepinephrine without use of midodrine as an adjuvant	Patients in group II with ongoing intravenous norepinephrine only

Timeline

• Start date: 2025-03-13
• Primary completion: 2025-10-13
• Completion: 2025-10-13
• First posted: 2025-04-16
• Last updated: 2025-04-16

Locations

1 site across 1 country: Egypt