NCT07467798

A Proof-of-concept Study of Ultrasound Stimulation of the Neck to Enhance Anti-shock Efficacy

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: Tao Liu · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The objective of this clinical study is to evaluate the initial efficacy and safety of LIPUS as an adjunct to standard therapy in patients with traumatic hypovolemic shock. The investigators will invite patients to participate in a proof-of-concept study investigating the efficacy of neck ultrasound stimulation to enhance anti-shock treatment, involving brief exposure to low-intensity pulsed ultrasound. This study examines whether LIPUS can enhance blood pressure in patients with traumatic hypotension, improve the efficacy of antihypotensive treatment, and reduce the dosage and duration of vasoactive drugs during active pharmacological therapy. By applying LIPUS as an adjunct to conventional treatment in clinical cases of traumatic hypotension, we aim to determine the clinical value of LIPUS and establish a theoretical foundation for developing innovative new therapies for hypotension.

Conditions

• Shock

Interventions

Type	Name	Description
DEVICE	Low-intensity pulsed ultrasound	During periods of stable blood pressure, administer cervical ultrasound stimulation (3-minute stimulation followed by a 2-minute interval, repeated cyclically; total stimulation duration not exceeding 60 minutes).

Timeline

• Start date: 2026-03-01
• Primary completion: 2027-03-01
• Completion: 2027-10-01
• First posted: 2026-03-12
• Last updated: 2026-03-12