| Not Yet Recruiting | Percutaneous Cryoablation of Intercostal Nerves for the Treatment of Rib Fractures NCT06533904 | Loma Linda University | N/A |
| Not Yet Recruiting | Vela Generation II: Usability and Performance of a Non-Invasive Ventilation Mask. NCT07484802 | Fisher and Paykel Healthcare | N/A |
| Not Yet Recruiting | High-Flow Nasal Cannula After Major Abdominal Surgery to Prevent Postoperative Pulmonary Complications NCT07528404 | Uijeongbu St. Mary Hospital | N/A |
| Not Yet Recruiting | A Clinical Trial of Early Ventilation in Amyotrophic Lateral Sclerosis (EVENT ALS) NCT07071935 | University of Pennsylvania | Phase 2 |
| Not Yet Recruiting | Compliance-Guided Abdominal Wall Closure Strategy in Large Ventral Hernia Repair NCT07422441 | Swissmed Hospital | N/A |
| Completed | Non-apnea Saline-contrast EIT for Lung Perfusion Imaging in Spontaneously Breathing Patients NCT07489950 | Ruijin Hospital | N/A |
| Completed | INSPIRatory Efforts Estimation Under High-flow Nasal Oxygen NCT07228676 | Poitiers University Hospital | N/A |
| Not Yet Recruiting | Inhaled Nitric Oxide in Severe Obesity NCT06675435 | Massachusetts General Hospital | N/A |
| Not Yet Recruiting | The Impact of Low Versus High Positive End-expiratory Pressure on Diaphragm Function, Ventilation Efficiency, NCT07188038 | Vastra Gotaland Region | N/A |
| Not Yet Recruiting | Early Sedation With Dexmedetomidine vs. Placebo in Older Ventilated Critically Ill Patients NCT06251375 | St. Joseph's Healthcare Hamilton | Phase 4 |
| Recruiting | Non-inferiority of Continuing Oral Intake Versus Fasting in Patients With Acute Respiratory Failure NCT06510972 | University Hospital, Tours | N/A |
| Active Not Recruiting | Retrospective Data Analysis With the Aim to Determine the Success Rate of Endotracheal Intubation in the First NCT06653166 | Rettungsdienst Zug | — |
| Recruiting | Noninvasive Ventilation Facemasks Favoring Carbon Dioxide Washout NCT06483984 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | N/A |
| Recruiting | Diaphragm Dysfunction and Ultrasound Perioperatively NCT05906030 | Karolinska University Hospital | — |
| Recruiting | Comparing Anticoagulation Strategies Using UFH, Argatroban and LMWH for ECMO Support NCT06442267 | Medical University of Vienna | Phase 4 |
| Recruiting | Comparison of Different Methods to Calculate Pendelluft by Electrical Impedance Tomography in Mechanically Ven NCT06494215 | University of Sao Paulo General Hospital | N/A |
| Recruiting | Effectiveness of Platform-Based Lateralization Therapy in Reducing Interface Pressure Between The Patient And NCT06819943 | University of Sao Paulo General Hospital | N/A |
| Completed | Wearable Wireless Respiratory Monitoring System That Detects and Predicts Opioid Induced Respiratory Depressio NCT06442488 | Jeffrey Joseph | — |
| Recruiting | Respiratory Functions, Thoracoabdominal Movements and Exercise Capacity in Neuromuscular Diseases NCT06756633 | Lokman Hekim University | — |
| Completed | REMINDers for Incentive Spirometry in PACU (REMIND-IS in PACU) NCT06304493 | University of Colorado, Denver | N/A |
| Recruiting | Home Versus Hospital Based NIV Care in MND NCT06844370 | Papworth Hospital NHS Foundation Trust | N/A |
| Completed | Nutrition Under Noninvasive Ventilation NCT06260202 | Università degli Studi del Piemonte Orientale Amedeo Avogadro | — |
| Terminated | Contribution of Nasal High Flow in Pneumology Assessed in Acid-Free Hypercapnic Acute Respiratory Failure NCT06008587 | Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer | N/A |
| Active Not Recruiting | NIV Mask and Headgear Evaluation NCT07391150 | Sheffield Children's NHS Foundation Trust | N/A |
| Recruiting | Multicenter HomeVENT: Home Values and Experiences Navigation Track NCT06102330 | Johns Hopkins University | N/A |
| Recruiting | Feasibility of Reducing Respiratory Drive Using the Through-flow System NCT05642832 | University Health Network, Toronto | N/A |
| Completed | Effectiveness of I COUGH Program to Dyspnea, Respiratory Parameters, Mobility and Pain After Major Abdominal S NCT06255327 | Yeditepe University | N/A |
| Unknown | Optimal Timing and Failure Prediction of High Flow Nasal Cannula Oxygen Therapy in Emergency Department: Prosp NCT06064409 | Yonsei University | — |
| Completed | Parasternal Intercostal Ultrasound vs RSBI for Weaning Prediction NCT07144878 | Benha University | N/A |
| Active Not Recruiting | Effect of Physiotherapy Methods on Functional and Respiratory Outcomes in ICU Patients With Respiratory Failur NCT06912308 | Laura Rutkauskienė | N/A |
| Completed | High Flow Nasal Oxygen at Extubation for Adults Requiring a Breathing Tube for Treating Severe Breathing Diffi NCT05904652 | NHS Greater Glasgow and Clyde | N/A |
| Recruiting | The Evaluation of the Effectiveness and Safety of Nalbuphine Hydrochloride Injection for Analgesia in ICU Pati NCT06785571 | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | Phase 2 / Phase 3 |
| Completed | Respiratory Depression of Remimazolam vs. Propofol for Monitored Anesthesia Care NCT07076628 | DongGuk University | Phase 4 |
| Recruiting | Combined Respiratory Training in Persons With ALS NCT05913882 | Nova Southeastern University | N/A |
| Unknown | Adherence to Low Tidal Volume in the Transition to Spontaneous Ventilation in Patients With Acute Respiratory NCT06042036 | University of Sao Paulo General Hospital | — |
| Recruiting | High Flow Nasal Cannulae vs Venturi Mask in Respiratory Failure Due to Pneumonia NCT03515031 | Papa Giovanni XXIII Hospital | N/A |
| Withdrawn | Evaluation of Leak-free Bronchoscope Adapter NCT05288218 | Columbia University | N/A |
| Recruiting | Platform of Randomized Adaptive Clinical Trials in Critical Illness NCT05440851 | University Health Network, Toronto | N/A |
| Recruiting | Respiratory Muscle Structure and Function in Mechanically Ventilated Patients and Long-term Outcomes NCT05857774 | University Health Network, Toronto | — |
| Active Not Recruiting | Safety and Performance of NivolisMonitor and NivolisAnton for Monitoring Patients on Ventilatory Assistance at NCT05698602 | VIVARDIS | N/A |
| Completed | The Effects of Different Prone Positioning Angles on Cardiopulmonary Function in Children After Congenital Hea NCT07323979 | Guangdong Provincial People's Hospital | N/A |
| Unknown | The Effect of Aromatherapy Massage on Pain, Anxiety and Comfort NCT06295874 | Nilgün Erdoğan | N/A |
| Completed | Extubation Guided by Bedside Ultrasound NCT05674812 | Lili Jia | — |
| Completed | Recruitment Manoeuvres in Critically Ill Patients NCT05508724 | University of Oxford | — |
| Unknown | Research on a NTHF to Improve Pulmonary Function in Patients With Respiratory Failure NCT05435079 | Shenzhen Second People's Hospital | N/A |
| Completed | ARM-ED: Advanced Respiratory Monitoring Events in Drug Toxicity NCT05358132 | NHS Greater Glasgow and Clyde | — |
| Completed | Inspiratory Muscle Training in Cerebral Palsy Patients NCT04915170 | University of Salamanca | N/A |
| Unknown | Evaluation of the Therapeutic Usability of RESPIRA ADVANCED Device in Patients Under Invasive Mechanical Venti NCT05174130 | Fundacion Clinic per a la Recerca Biomédica | N/A |
| Completed | Physiotherapy in Emergency Department: a Service Analysis From a French Hospital NCT06528899 | Université de Nantes | — |
| Unknown | Volume Mode Non-invasive Ventilation in Amyotrophic Lateral Sclerosis NCT05328492 | University Hospitals Coventry and Warwickshire NHS Trust | N/A |
| Completed | Non-invasive Ventilation and Dex in Critically Ill Adults NCT04878510 | St. Joseph's Healthcare Hamilton | Phase 3 |
| Recruiting | Efficacy of Early Inspiratory Muscle Training in Lung Transplanted Patients NCT05271019 | Puerta de Hierro University Hospital | N/A |
| Terminated | Clinical Efficacy in Relief of Dyspnea by HVNI: Evaluation of New Device Equivalence NCT04590014 | Vapotherm, Inc. | N/A |
| Unknown | Effect of Different Sedation and Analgesia Strategies on Patients With Mechanical Ventilation NCT05024799 | The Affiliated Hospital of Qingdao University | Phase 4 |
| Active Not Recruiting | Feasibility and Efficacy of Automated Lateral Decubitus Therapy in Hypoxemic Respiratory Failure NCT06698913 | University of Sao Paulo General Hospital | N/A |
| Completed | Weaning Success in Different Weaning Strategies in Early Neurological Rehabilitation Patients - a Matched-pair NCT05483244 | BDH-Klinik Hessisch Oldendorf | — |
| Active Not Recruiting | Delayed Cord Clamping With Oxygen In Extremely Low Gestation Infants NCT04413097 | Sharp HealthCare | N/A |
| Completed | The Use of ExPreS in the Weaning of Patients in Invasive Mechanical Ventilation NCT05085457 | Universidade do Oeste de Santa Catarina | N/A |
| Unknown | Robot-assisted and Connected 6-minute Walk Test (TM6) NCT05084287 | Association Nationale pour les Traitements A Domicile, les Innovations et la Recherche | — |
| Completed | Pathophysiology of Gas Exchange and Time Course Changes in Spontaneously Breathing Patients With Acute Respira NCT05392062 | CHU de Reims | N/A |
| Completed | Closed-loop Oxygen Control for High Flow Nasal Therapy NCT04965844 | Hospital Universitari Vall d'Hebron Research Institute | N/A |
| Unknown | More Air - Better Performance - Faster Recovery NCT04686019 | Central Jutland Regional Hospital | N/A |
| Completed | Early Physiotherapy in Covid Patients NCT05032885 | Hospital Universitario Getafe | N/A |
| Completed | Bioelectrical Impedance in Monitoring Hyperhydration and Polyneuromyopathy in Critically Ill Patients NCT05991778 | University Hospital Ostrava | — |
| Unknown | Post COVID-19 Pulmonary Rehabilitation Program NCT04982042 | Centro Universitário de Anapolis | N/A |
| Unknown | BIA Assessment of Polymyoneuropathy in Critically Ill Patients NCT04758676 | University Hospital Ostrava | N/A |
| Completed | Totally Transdermal Sedation in the Weaning From Remifentanil Infusion NCT04204967 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | Phase 2 |
| Unknown | Thoracoabdominal Asynchrony and Respiratory Distress NCT04626154 | Massachusetts General Hospital | N/A |
| Recruiting | Partial Neuromuscular Blockade in Acute Hypoxemic Respiratory Failure NCT04524585 | University Health Network, Toronto | N/A |
| Completed | Clinical Efficacy in Relief of Dyspnea by HVNI: Evaluation of New Cannulae Designs NCT04512781 | Vapotherm, Inc. | N/A |
| Completed | Telmisartan in Respiratory Failure Due to COVID-19 NCT04510662 | Abraham Edgar Gracia-Ramos | Phase 2 |
| Terminated | Pemziviptadil (PB1046), a Long-acting, Sustained Release Human VIP Analogue, Intended to Provide Clinical Impr NCT04433546 | PhaseBio Pharmaceuticals Inc. | Phase 2 |
| Recruiting | Doxapram Therapy in Preterm Infants (DOXA Trial) NCT04430790 | Erasmus Medical Center | Phase 3 |
| Completed | Timing of Tracheotomy in Covid-19 Patients NCT04412356 | Sahlgrenska University Hospital | N/A |
| Completed | Development of a Tracheal Sound Sensor NCT05506267 | Thomas Jefferson University | — |
| Unknown | Airway Clearance Using Non-Invasive Oscillating Device NCT03821389 | St. Justine's Hospital | Phase 2 / Phase 3 |
| Completed | COVid-19: Awake Proning and High-flow Nasal Cannula in respiratorY DistrEss NCT04395144 | Hôpital de Verdun | N/A |
| Unknown | Convalescent Plasma in the Treatment of Covid-19 NCT04600440 | Skane University Hospital | N/A |
| Unknown | Ventil Device Usefulness in Mechanically Ventilated ICU Patients NCT04355754 | Medical University of Gdansk | N/A |
| Completed | Personalised Simulation Technologies for Optimising Treatment in the Intensive Care Unit NCT04297397 | Guy's and St Thomas' NHS Foundation Trust | — |
| Unknown | Evaluation Of The Efficacy Of Four Different Non-invasive Ventilation Modes Performed In The Delivery Room NCT04282369 | Kanuni Sultan Suleyman Training and Research Hospital | N/A |
| Unknown | Preventive Versus Curative Treatment of Fluid Overload NCT04050007 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | High-Flow Nasal Oxygen Cannula Compared to Non-Invasive Ventilation in Adult Patients With AcuTE Respiratory F NCT03643939 | Hospital do Coracao | N/A |
| Completed | Muscular Respiratory Involvement and Systemic Sclerosis NCT04118725 | Poitiers University Hospital | N/A |
| Completed | Outcome After Non-invasive Ventilation. NCT04115969 | Jakob Wallden | — |
| Completed | Automated Oxygen Control by O2matic to Patients Admitted With Acute Hypoxemia NCT04079465 | Hvidovre University Hospital | N/A |
| Withdrawn | TC02 Obese Women Using It Morphine vs PCA IV Hydromorphone for Post-Cesarean Analgesia NCT03282669 | Northwestern University | Phase 4 |
| Unknown | Effect of HFNO on Spontaneous Ventilation in Obese Patients During Analgo-sedation for Vitrectomy NCT04049240 | University of Split, School of Medicine | N/A |
| Unknown | Influence of HFNO on Spontaneous Ventilation in Patients of Different ASA Risk During Analgo-sedation for Vitr NCT04055077 | University of Split, School of Medicine | N/A |
| Completed | Sonographic Evaluation of Diaphragmatic Function Under Nasal High-flow (NHF) and Non-invasive Ventilation (NIV NCT07050147 | Klinikum Emden | N/A |
| Completed | "TRAcheostomy With Single Use Bronchoscopes vs. Conventional Bronchoscopes" NCT03952247 | Universitätsklinikum Hamburg-Eppendorf | N/A |
| Completed | "Inspiratory Muscle Training in Older Women" NCT03827356 | University of Salamanca | N/A |
| Suspended | Use of Autologous Stem/Stromal Cells In Chronic Lung Disorders: Obstructive (COPD) & Restrictive (RLD) NCT03909750 | Healeon Medical Inc | Phase 1 |
| Terminated | Nasal High-frequency Jet Ventilation (nHFJV) Following Extubation in Preterm Infants NCT03558737 | University of Utah | N/A |
| Completed | Post -Extubation Respiratory Failure NCT04441736 | Cairo University | N/A |
| Terminated | Comparison of Oxygen Controllers in Preterm InfanTs NCT03877198 | Leiden University Medical Center | N/A |
| Completed | Cognitive and Behavioral Intervention for the Management of Episodic Breathlessness in Patients With Advanced NCT04630743 | University of Cologne | N/A |
| Completed | Lung and Diaphragm-Protective Ventilation by Means of Assessing Respiratory Work NCT03612583 | University Health Network, Toronto | Phase 1 |
| Completed | Weaning Protocol for High Flow Nasal Cannula Oxygen Therapy NCT03845244 | Seoul National University Hospital | N/A |
| Unknown | Effectiveness Inspirational Muscle Training NCT03758573 | Universidade Federal do vale do São Francisco | N/A |
| Completed | Oxygen Control and Weaning by O2matic to Patients Admitted With an Exacerbation of COPD NCT03661086 | Hvidovre University Hospital | N/A |
| Completed | HVNI Ambulation Feasibility Study NCT03885726 | Vapotherm, Inc. | N/A |
| Unknown | The Effect of High-flow Nasal Oxygenation to the Saturation During Analgo-sedation in Different ASA Risk Class NCT03687385 | Anita Vukovic | N/A |
| Unknown | Can High-flow Nasal Oxygenation Improve Oxygen Saturation During Analgo-sedation in Obese Adults? NCT03687424 | University of Split, School of Medicine | N/A |
| Unknown | Weaning Algorithm for Mechanical VEntilation NCT03697785 | Royal Brompton & Harefield NHS Foundation Trust | N/A |
| Completed | Evaluating Safety and Efficacy of Umbulizer in Patients Requiring Intermittent Positive Pressure Ventilation NCT04030208 | Umbulizer LLC | N/A |
| Completed | Is There an Association Between Chronic Pancreatitis and Pulmonary Function NCT03850977 | Copenhagen University Hospital, Hvidovre | — |
| Unknown | Partial Neuromuscular Blockade for Lung Protective Mechanical Ventilation NCT03646266 | Amsterdam UMC, location VUmc | Phase 4 |
| Terminated | Entrainment-Based Mechanical Ventilation NCT03512067 | Brigham and Women's Hospital | N/A |
| Completed | Respiratory Rate Accuracy Verification Clinical: Pulmonary Rehabilitation Patients NCT03592914 | Nonin Medical, Inc | — |
| Completed | The Impact of High-Flow Nasal Cannula on Swallow Function NCT03590457 | Rush University Medical Center | N/A |
| Unknown | Study of the Prevalence of Painful Symptoms of the Musculoskeletal System After Lung Transplantation NCT03636802 | Assistance Publique Hopitaux De Marseille | — |
| Terminated | The Edi Level and Cardiopulmonary Function Between HHHFNC and Unheated Humidified High-Flow Oxygen Mask in COP NCT03811158 | Fu Jen Catholic University | N/A |
| Completed | Automated Oxygen Delivery by O2matic to Patients Admitted With an Exacerbation in COPD NCT03464695 | Hvidovre University Hospital | N/A |
| Recruiting | KAP Asynchrony Survey NCT03439683 | University of Sao Paulo General Hospital | — |
| Completed | Behavioral Activation-Rehabilitation to Improve Depressive Symptoms & Physical Function After Acute Respirator NCT03431493 | Johns Hopkins University | N/A |
| Unknown | Physiotherapy for Infants With Bronchiolities NCT03575091 | Lund University | N/A |
| Unknown | High Flow Nasal Oxygen Therapy in Pediatric Hypercapnic Respiratory Failure During Perioperative Stage NCT03534960 | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | N/A |
| Completed | Transpulmonary Pressures in Mechanical Ventilated Patients With Morbid Obesity NCT02309190 | The University of Texas Health Science Center, Houston | — |
| Completed | Сohort Study to Evaluate Exacerbations, Respiratory Symptoms, Physical Exercise Intolerance and Lung Functions NCT03383601 | Kazakhstan Academy of Preventive Medicine | — |
| Completed | Correlation of Two Methods for Cough Peak Flow Measurement in Intubated Patients NCT03357198 | Centre Hospitalier Régional d'Orléans | — |
| Unknown | Capnography in the Post-Anesthesia Care Unit (PACU) NCT03076047 | University of South Florida | — |
| Unknown | Is Venous to Arterial Conversion (v-TAC) of Blood Gas Reliable in Critical Ill Patients in the ICU? NCT03309423 | Aalborg University | — |
| Completed | Compliance in Non Invasive Mechanical Ventilation NCT05379309 | Glostrup University Hospital, Copenhagen | — |
| Completed | Inspiratory Muscle Training Post-Liver Transplant NCT03130608 | University of Miami | N/A |
| Completed | A Comparison of Three Nutritional Assessment Methods Predicting Prognosis in COPD With Respiratory Failure NCT02942784 | West China Hospital | — |
| Completed | Incidence Of Hemidiaphragmatic Paralysis After Usg Guided Low Dose Interscalene Brachial Plexus Block NCT03081728 | Post Graduate Institute of Medical Education and Research, Chandigarh | N/A |
| Completed | NRS 2002 as a Predictor of Prognosis in COPD With Respiratory Failure NCT02942797 | West China Hospital | — |
| Completed | Determination of the Clinical Impact of Continuous Surveillance Monitoring (SM) and Utility of IPI. NCT03050983 | Medtronic - MITG | — |
| Completed | Systematic Evaluation by an Intensivist of Hematological Malignancy Patients Presenting With Acute Respiratory NCT03399149 | University Hospital, Grenoble | — |
| Completed | Influence of a Multi-parametric Optimization Strategy for General Anesthesia on Postoperative Morbidity and Mo NCT02668250 | Centre Hospitalier Universitaire de Saint Etienne | N/A |
| Completed | The PROtective Ventilation Using Open Lung Approach Or Not Trial NCT03160144 | Sixth Affiliated Hospital, Sun Yat-sen University | N/A |
| Completed | Fluid Responsiveness in HFNC Patients NCT03817996 | Hospital Universitari Vall d'Hebron Research Institute | — |
| Completed | Mobilization Immediate After Abdominal Surgery NCT02929446 | Karolinska Institutet | N/A |
| Completed | Efficacy of Different Respiratory Methods in Intensive Care NCT04108585 | Trakya University | — |
| Completed | Respiratory Mechanics and Patient-ventilator Asynchrony Index in Patients With Invasive Mechanical Ventilation NCT02687802 | University of Sao Paulo General Hospital | — |
| Completed | Effect of High Flow Nasal Cannula vs. Standard Care on Respiratory Stability in Pediatric Procedural Sedation NCT02930525 | University of Freiburg | N/A |
| Unknown | Fluid Restriction Keeps Children Dry NCT02989051 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | Phase 2 / Phase 3 |
| Completed | Effect of Neuromuscular Blockade and Reversal on Breathing NCT02845375 | Leiden University Medical Center | Phase 4 |
| Completed | Monitoring Intercostal Muscles After Extubation NCT02853201 | Unity Health Toronto | — |
| Completed | Music Therapy During Pediatric Extubation Readiness Trials NCT02845947 | Northwell Health | N/A |
| Unknown | The Role of Muscular Ultrasound in Predicting Weaning Success NCT02864459 | Seoul National University Hospital | N/A |
| Unknown | Effectiveness of the Routine Use of Extubation Protocol on the Incidence of Occurrence of Failures Number of E NCT03129815 | University Hospital, Strasbourg, France | — |
| Unknown | Incidence and Risk Factors of Extubation Failure in Pediatric Resuscitation NCT03129802 | University Hospital, Strasbourg, France | — |
| Completed | Change of Regional Ventilation During Spontaneous Breathing After Lung Surgery NCT02779595 | Wuerzburg University Hospital | — |
| Completed | Astral VAPS AutoEPAP Clinical Trial NCT02683772 | ResMed | Phase 3 |
| Completed | VivaSight-SL™ Versus Bronchoscopy for Percutaneous Tracheotomy NCT02861001 | Universitätsklinikum Hamburg-Eppendorf | N/A |
| Unknown | Open Lung Strategy in Critically Ill Morbid Obese Patients NCT02503241 | Massachusetts General Hospital | N/A |
| Completed | Conventional Intubation Versus VivaSight™-SL NCT02837055 | Universitätsklinikum Hamburg-Eppendorf | N/A |
| Completed | Implementation of Lung Protective Ventilation in Patients With Acute Respiratory Failure NCT03225807 | Intermountain Health Care, Inc. | — |
| Unknown | Nasal High Frequency Oscillatory Versus Nasal Intermittent Positive Pressure Ventilation in Neonate After Extu NCT02543125 | Gao WeiWei | N/A |
| Unknown | Humidified High Flow Nasal Cannula Versus Nasal Intermittent Positive Ventilation in Neonates NCT02499744 | Gao WeiWei | Phase 1 |
| Completed | Effect of Sleep Disruption on the Outcome of Weaning From Mechanical Ventilation NCT02464735 | Unity Health Toronto | — |
| Completed | Evaluation of Monitoring TECHNOlogies in the PERI-OPerative Care of Cardiac Surgical Patients NCT02658006 | Montreal Heart Institute | — |
| Completed | NIV-NAVA vs NIV-PS/PC in Respiratory Insufficiency NCT02592512 | Vejle Hospital | — |
| Unknown | Prediction of Outcome of Weaning From Mechanical Ventilation Using the Electrical Activity of the Diaphragm NCT02539732 | Unity Health Toronto | — |
| Unknown | Description of Fluid Balance in Patients With Acute Respiratory Failure NCT02523872 | Smiths Medical, ASD, Inc. | — |
| Completed | High-flow Nasal Cannula Oxygen Versus Conventional Oxygen Therapy After Pulmonary Lobectomy NCT02544477 | Catholic University of the Sacred Heart | N/A |
| Completed | Assessing Diaphragm Muscle Inactivity in Mechanically Ventilated ICU Patients NCT02434016 | Unity Health Toronto | — |
| Terminated | Juno Perth Clinical Trial NCT02317042 | ResMed | N/A |
| Completed | Low Creatinine Level and Respiratory Failure NCT04368325 | Osijek University Hospital | — |
| Unknown | Effects of High Flow Nasal Cannula on Deadspace Reduction and Regional Distribution of Ventilation NCT02460653 | Boston Children's Hospital | N/A |
| Terminated | Evaluation of a Disposable Flexible Bronchoscope, aScope IV NCT02255838 | University of Louisville | N/A |
| Completed | A New Method for Estimating Dynamic Intrinsic PEEP NCT02388282 | IRCCS Azienda Ospedaliero-Universitaria di Bologna | — |
| Completed | Comparison of High-flow Oxygen vs. BiPAP in Type II (Hypercapnic) Respiratory Failure NCT03443479 | Hôpital de Verdun | — |
| Completed | A Feasibility Study Evaluating the Use of a Non-invasive Ventilation Mask NCT02383719 | Convergent Engineering, Inc. | N/A |
| Completed | Effect of Non-invasive Ventilation (NIV) on Cerebral Oxygenation NCT02454582 | Ass.-Prof. PD Dr. Klaus Ulrich Klein | Phase 4 |
| Withdrawn | Respiratory Weaning Following Cardiac Surgery. NCT02821429 | University Hospital, Toulouse | — |
| Completed | Perioperative Change of Regional Ventilation During Spontaneous Breathing NCT02419196 | Wuerzburg University Hospital | — |
| Unknown | Cohort of Respiratory Failure Patients Treated for the First Time With Non-Invasive Ventilation at Home NCT02346305 | Association Nationale pour les Traitements A Domicile, les Innovations et la Recherche | — |
| Completed | Airway Pressure During Nasal High Flow and CPAP in Neonates NCT02632799 | Research Center of Maternal and Child Health Protection, Armenia | N/A |
| Unknown | Monitored Saturation Post-ICU NCT02290236 | Karolinska University Hospital | — |
| Completed | Biofilm Formation on Different Endotracheal Tube Materials NCT02284438 | Region Skane | N/A |
| Completed | Flow-synchronized Nasal IMV in Preterm Infants NCT02085499 | University of Miami | N/A |
| Completed | A Diaphragmatic Electrical Activity Based Optimization Strategy During Pressure Support Ventilation NCT02067403 | Unity Health Toronto | N/A |
| Completed | APRV/BIPAP With Spontaneous Breathing on Lung Protection NCT02071277 | Unity Health Toronto | N/A |
| Completed | A Study of Rivaroxaban (JNJ-39039039) on the Venous Thromboembolic Risk in Post-Hospital Discharge Patients NCT02111564 | Janssen Research & Development, LLC | Phase 3 |
| Completed | Randomized Crossover of NAVA and Synchronized Intermittent Pressure Ventilation in Neonates and Infants NCT02518230 | Children's Mercy Hospital Kansas City | N/A |
| Unknown | Video Laryngoscopy in Pre-hospital Critical Care NCT02035449 | University of Aarhus | — |
| Unknown | Helm CPAP Versus Mask CPAP After Major Abdominal Surgery NCT02173327 | Rigshospitalet, Denmark | N/A |
| Completed | RCT of Mesh Versus Jet Nebulizers on Clinical Outcomes During Mechanical Ventilation in the Intensive Care Uni NCT02056119 | Rush University Medical Center | N/A |
| Unknown | Changes in Spontaneous Ventilation in Response to Changes in Extracorporeal Carbon Dioxide Removal NCT01953484 | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | N/A |
| Completed | Diaphragm Injury and Dysfunction During Mechanical Ventilation NCT03108118 | University Health Network, Toronto | — |
| Completed | Impact of the Assisted Ventilation Mode on Diaphragm Efficiency in Critically Ill Patients NCT02473172 | University of Bari | Phase 2 |
| Completed | Local Assessment of Ventilatory Management During General Anesthesia for Surgery NCT01601223 | European Society of Anaesthesiology | — |
| Completed | Noninvasive Ventilation Bundle in Postoperative Respiratory Failure NCT02214368 | West China Hospital | N/A |
| Completed | Extracorporeal Lung Assist to Avoid Intubation in Patients Failing Noninvasive Ventilation for Hypercapnic ARF NCT01784367 | Universitätsklinikum Hamburg-Eppendorf | N/A |
| Unknown | Outcome Evaluation of Patients After Percutaneous Tracheostomy Due to Respiratory Failure in an Intensive Care NCT01693705 | Hillel Yaffe Medical Center | — |
| Terminated | Early Stage Amyotrophic Lateral Sclerosis Phrenic Stimulation NCT01583088 | Assistance Publique - Hôpitaux de Paris | Phase 3 |
| Completed | Assessment of an Endotracheal Tube Securement Device NCT01651260 | Hollister Incorporated | N/A |
| Unknown | Non-invasive Measurements of Elastance and Resistance NCT01530282 | University of Turin, Italy | Phase 2 |
| Unknown | Physiological Response to Heliox21 and Air O2 NCT01498432 | University College, London | Phase 4 |
| Completed | Study of High Flow Nasal Cannula Oxygen for Bronchoscopy With Bronchoalveolar Lavage in ICU Patients NCT02523573 | Hôpital Louis Mourier | — |
| Terminated | Inhaled Prostaglandin E1 (IPGE1) for Hypoxemic Respiratory Failure (NHRF) NCT01467076 | NICHD Neonatal Research Network | Phase 2 |
| Completed | Respiratory Complications After Laparoscopic Surgery NCT01476254 | Herlev Hospital | — |
| Completed | Adjustment of Mask Pressure, for Bilevel Positive Airways Pressure Therapy, by Automated Algorithm NCT01403584 | ResMed | N/A |
| Completed | Neurally Adjusted Ventilatory Assist (NAVA) in NonInvasive Ventilation (NIV) NCT01426178 | University Hospital, Clermont-Ferrand | Phase 1 |
| Unknown | Systematic Team Approach to Guide Early Mobilization in Surgical Intensive Care Unit Patients NCT01363102 | Massachusetts General Hospital | N/A |
| Completed | High Flow Nasal Cannula Versus Nasal Continuous Positive Airway Pressure NCT01531465 | Christiana Care Health Services | N/A |
| Completed | Capnography Library - Data Collection in the Critical Care Environment Stage 2 NCT01354769 | Shaare Zedek Medical Center | — |
| Completed | BIPAP Vision Versus OPTIFLOW System Comparison in Acute Respiratory Failure After Cardio Thoracic Surgery NCT01458444 | Centre Chirurgical Marie Lannelongue | N/A |
| Completed | Pressure-limited Ventilation Versus Volume-targeted Ventilation in Term Newborns NCT02358460 | King's College London | N/A |
| Withdrawn | Integrated Pulmonary Index (IPI) as a Determinate of Weaning Success and/or Failure in the Pediatric Populatio NCT01795196 | Rush University Medical Center | — |
| Completed | Novel Non-Invasive Monitoring Parameter in a Hospital Setting NCT01306201 | Medtronic - MITG | — |
| Completed | Feeding Children Nasogastrically Versus Nasojejunally While Receiving Noninvasive Positive Pressure Ventilatio NCT01301352 | McGill University Health Centre/Research Institute of the McGill University Health Centre | N/A |
| Completed | Study of the Usability and Efficacy of a New Pediatric CPAP Mask NCT01312948 | ResMed | N/A |
| Completed | Influence Positive End-expiratory Pressure on Autoregulation in Patients With Respiratory Insufficiency NCT01376518 | Johannes Gutenberg University Mainz | — |
| Unknown | Efficacy and Tolerance of Early Launching of Nocturnal Non Invasive NCT01225614 | Assistance Publique - Hôpitaux de Paris | Phase 3 |
| Unknown | Inflammatory Effects of a Lung Recruitment Manoeuvre NCT01070654 | Azienda Ospedaliero, Universitaria Pisana | N/A |
| Terminated | Effects of Physiotherapy in Hemodynamics and Childrens Respiratory Mechanics NCT01747954 | Federal University of Uberlandia | N/A |
| Completed | Helmet Continuous Positive Airway Pressure (CPAP) Versus Oxygen Venturi in Severe Acute Respiratory Failure in NCT01383213 | University of Milan | N/A |
| Completed | Study Using Citrate to Replace Heparin in Babies Requiring Extracorporeal Membrane Oxygenation (ECMO) NCT00968565 | Vanderbilt University | EARLY_Phase 1 |
| Completed | Transcutaneous Carbon Dioxide Monitoring Post Cardiac Surgery: Incidence and Severity Resp Insufficiency NCT01188590 | Baylor Research Institute | — |
| Withdrawn | High Flow Therapy (HFT) to Treat Respiratory Insufficiency in Chronic Obstructive Pulmonary Disease (COPD) NCT00990119 | Vapotherm, Inc. | N/A |
| Unknown | Mortality and Risk Factors in Patients With Acute Cardiogenic Pulmonary Edema: a Multicentric, Observational, NCT01269177 | University of Milan | — |
| Completed | Cross-over Comparison of the V60 System to Other Bi-Level Noninvasive Ventilators NCT00817297 | Respironics, California, Inc. | N/A |
| Completed | Cross-over Comparison of the V60 System to Other Bi-Level Noninvasive Ventilators NCT00817804 | Respironics, California, Inc. | N/A |
| Completed | Sedation Management in Pediatric Patients With Acute Respiratory Failure (The RESTORE Study) NCT00814099 | University of Pennsylvania | Phase 3 |
| Completed | Broncho-alveolar Lavage Under Noninvasive Ventilation With Propofol TCI in Patient With AHRF NCT00741949 | University Hospital, Bordeaux | Phase 3 |
| Completed | Electrical Activity of the Diaphragm During the Weaning Period NCT01411722 | University of Turin, Italy | Phase 2 |
| Completed | Pulmonary Rehabilitation in Patients Before Lung Transplantation (LTx) NCT00962078 | Schön Klinik Berchtesgadener Land | N/A |
| Unknown | Comparative Study of Non-Invasive Mask Ventilation vs Cuirass Ventilation in Patients With Acute Respiratory F NCT00331656 | Hadassah Medical Organization | Phase 4 |
| Terminated | Continuous Positive Airway Pressure (CPAP) Ventilation Using a Novel Full-Face Mask Versus Conventional Helmet NCT00944437 | University of Parma | N/A |
| Withdrawn | Inhaled PGE1 in Neonatal Hypoxemic Respiratory Failure NCT00598429 | NICHD Neonatal Research Network | Phase 2 |
| Completed | Effects of Remifentanil on Respiratory Function in Mechanically Ventilated Patients NCT00665119 | Fondazione Poliambulanza Istituto Ospedaliero | Phase 4 |
| Completed | Trilogy Comparison Study - Adults NCT00810498 | Philips Respironics | N/A |
| Terminated | Clinical Trial of a Computer-driven Weaning System for Patients Requiring Mechanical Ventilation NCT00606554 | Boston Medical Center | N/A |
| Completed | Comparison of Humidified High Flow Nasal Cannula to Nasal CPAP in Neonates NCT00609882 | University of Utah | N/A |
| Completed | Investigation of Efficiency of Breathing With Different Breathing Patterns NCT00784004 | Massachusetts General Hospital | N/A |
| Completed | B-type Natriuretic Peptide for the Management of Weaning NCT00473148 | Assistance Publique - Hôpitaux de Paris | Phase 3 |
| Completed | A Comparison of High vs. Low Tidal Volumes in Ventilator Weaning for Individuals With Cervical Spinal Cord Inj NCT00412308 | Craig Hospital | N/A |
| Completed | Effects Of Invasive And Noninvasive Mechanical Ventilation On Sleep In The Intensive Care Unit (ICU) NCT00638339 | Tufts Medical Center | — |
| Terminated | Sedation Versus No Sedation in a Spontaneous Breathing Trial NCT00366353 | Memorial Medical Center | N/A |
| Completed | 24-Hour NAVA Ventilation in Acute Respiratory Failure NCT00583037 | Unity Health Toronto | N/A |
| Completed | Brain Natriuretic Peptide (BNP) Levels in Patients in Non Invasive Mechanical Ventilation NCT00453726 | Ospedale S. Giovanni Bosco | — |
| Terminated | Enteral Glutamine in Critical Illness NCT00318331 | Christiana Care Health Services | Phase 2 / Phase 3 |
| Unknown | Analgesia-Based Sedation During Mechanical Ventilation NCT00403208 | Pontificia Universidad Catolica de Chile | N/A |
| Completed | Nasal High Frequency Ventilation in Preterm Infants: A Pilot Study NCT00296231 | Tarah T Colaizy | Phase 1 |
| Terminated | Effects of Obesity on Care and Outcomes in Mechanically Ventilated Individuals in the Intensive Care Unit NCT00296088 | Ohio State University | — |
| Terminated | Helmet Continuous Positive Airway Pressure Versus Oxygen Venturi in Acute Respiratory Failure in CAP: CAPOVeRS NCT00603564 | University of Milan | N/A |
| Unknown | Ketamine Sedation in Mechanically Ventilated Patients NCT00122759 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | Loxapine and Weaning From Ventilator NCT00122733 | Assistance Publique - Hôpitaux de Paris | N/A |
| Withdrawn | Use of the Hattler Respiratory Assist Catheter in Severe Respiratory Failure NCT00288964 | Alung Technologies | Phase 3 |
| Terminated | Assessment of the Effectivity of Total-face Mask for Noninvasive Ventilation During Acute Respiratory Failure NCT00243828 | Corporacion Parc Tauli | Phase 4 |
| Completed | Influence of Muscular Atrophy on Biological and Functional Benefit of Respiratory Rehabilitation in Patients W NCT00922857 | Centre Hospitalier Universitaire de Saint Etienne | N/A |
| Completed | Out-of-Hospital Non-Invasive Ventilation for Patients With Acute Respiratory Failure NCT00885898 | University of Göttingen | N/A |
| Unknown | Hemofiltration for Respiratory Failure After Bone Marrow Transplantation NCT00120575 | Stanford University | Phase 2 / Phase 3 |
| Completed | Australia and New Zealand Adult Extracorporeal Membrane Oxygenation (ECMO) Audit 2005 NCT00157144 | Bayside Health | — |
| Unknown | Immunonutrition and Thoracoabdominal Aorta Aneurysm Repair NCT00339053 | St. Antonius Hospital | Phase 4 |
| Completed | Efficacy of Early Tracheostomy to Reduce Incidence of Ventilator Acquired Pneumonia (VAP) NCT00262431 | University of Turin, Italy | Phase 3 |
| Completed | Comparison of Central and Peripheral Venous Catheters NCT00122707 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | Music Therapy for Patients Being Weaned From Mechanical Ventilation NCT00178139 | University of Rochester | Phase 1 |
| Completed | B-type Natriuretic Peptide (BNP)-Guided Diagnostic Strategy in Intensive Care Unit (ICU) Patients With Respira NCT00130559 | University Hospital, Basel, Switzerland | Phase 4 |
| Unknown | Comparison of Two Methods of Continuous Positive Airway Pressure (CPAP) to Support Successful Extubation of In NCT00187434 | Sunnybrook Health Sciences Centre | N/A |
| Completed | Prehospital CPAP vs. Usual Care for Acute Respiratory Failure NCT00405314 | Dalhousie University | N/A |
| Terminated | Early Tracheotomy Versus Prolonged Endotracheal Intubation in Intensive Care Unit (ICU) Patients NCT00127621 | Gustave Roussy, Cancer Campus, Grand Paris | Phase 3 |
| Completed | Acetazolamide for Respiratory Failure in Combination With Metabolic Alkalosis NCT00222534 | University of Oslo School of Pharmacy | Phase 4 |
| Terminated | Effects of Inhaled Nitric Oxide in the Treatment of Acute Hypoxemic Respiratory Failure (AHRF) in Pediatrics NCT00041561 | Mallinckrodt | Phase 3 |
| Terminated | Early Surfactant to Reduce Use of Mechanical Breathing in Low Birth Weight Infants NCT00005774 | NICHD Neonatal Research Network | Phase 3 |
| Terminated | Early Inhaled Nitric Oxide for Respiratory Failure in Newborns NCT00005773 | NICHD Neonatal Research Network | Phase 3 |
| Terminated | Inhaled Nitric Oxide Study for Respiratory Failure in Newborns NCT00005776 | NICHD Neonatal Research Network | Phase 3 |
| Completed | Tracheobronchial Secretion Removal NCT00932776 | University of Milano Bicocca | N/A |