NCT01531465

High Flow Nasal Cannula Versus Nasal Continuous Positive Airway Pressure

Pulmonary Function Testing in Infants With Respiratory Insufficiency While Receiving High Flow Nasal Cannula (HFNC) Versus Nasal Continuous Positive Airway Pressure (nCPAP)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Christiana Care Health Services · Academic / Other
• Sex: All
• Age: 2 Days – 6 Months
• Healthy volunteers: Accepted

Summary

The purpose of this study is to compare two common methods of providing respiratory support: nasal continuous airway pressure and high flow nasal cannula to see what effect it has on babies breathing. The investigators also will compare the effects of slightly changing the level of support these two different types of therapy on how easily your baby is breathing. Changes in the level of support and between these two respiratory support modalities are frequently done and are part of the routine care in the neonatal intensive care unit.

Conditions

• Respiratory Insufficiency

Interventions

Type	Name	Description
OTHER	Pulmonary Function Testing & esophageal pressure monitoring	Infants who are currently on NCPAP will have pulmonary function testing (PFTs)and esophageal pressure performed while on 2 different settings of NCPAP. These infants will then be transitioned HFNC and will undergo PFTs and esophageal pressure while on different HFNC settings. The infant will then be returned to NCPAP at the same settings they were on prior to any study interventions.
OTHER	Pulmonary function testing and esophageal pressure	Infants who are currently on HFNC will have pulmonary function testing (PFTs) and esophageal pressure performed while on 2 different settings of HFNC. These infants will then be transitioned NCPAP and will undergo PFTs and esophageal pressure while on 2 different NCPAP settings. The infant will then be returned to HFNC at the same settings they were on prior to any study interventions.

Timeline

• Start date: 2011-06-01
• Primary completion: 2012-10-01
• Completion: 2013-01-01
• First posted: 2012-02-13
• Last updated: 2013-06-04

Locations

1 site across 1 country: United States