NCT00665119

Effects of Remifentanil on Respiratory Function in Mechanically Ventilated Patients

Effects of Remifentanil on Breathing Pattern, Respiratory Effort and Gas Exchange in Mechanically Ventilated Patients.

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 14 (actual)
• Sponsor: Fondazione Poliambulanza Istituto Ospedaliero · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Sedation is widely used in mechanically ventilated patients. Propofol, benzodiazepines and opioids are the most used drugs. The study hypothesis is that sedation with remifentanil (an opioid drug) could improved respiratory pattern and effort in mechanically ventilated patients with rapid shallow breathing or high respiratory rate.

Conditions

• Respiratory Insufficiency
• Respiration, Artificial
• Conscious Sedation

Interventions

Type	Name	Description
DRUG	remifentanil	0.05 mcg.kg-1.min-1 for 30 minutes by continuous endovenous infusion
DRUG	placebo	NaCl 0.9 %

Timeline

• Start date: 2008-04-01
• Primary completion: 2008-10-01
• Completion: 2008-10-01
• First posted: 2008-04-23
• Last updated: 2008-12-18

Locations

1 site across 1 country: Italy