NCT03534960

High Flow Nasal Oxygen Therapy in Pediatric Hypercapnic Respiratory Failure During Perioperative Stage

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 150 (estimated)
• Sponsor: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine · Academic / Other
• Sex: All
• Age: 1 Year – 18 Years
• Healthy volunteers: Not accepted

Summary

Humidified high flow nasal oxygen therapy decreases dilution of the inhaled oxygen and, by matching patient's peak flow, allows accurate delivery of the set FiO2 throughout the whole inspiratory phase.The purpose of this study is to determine the impact of hign-flow nasal therapy on pediatric hypercapnic respiratory failure by comparing with nasal continuous positive airway pressure.

Detailed description

Humidified high flow nasal oxygen therapy decreases dilution of the inhaled oxygen and, by matching patient's peak flow, allows accurate delivery of the set FiO2 throughout the whole inspiratory phase.The purpose of this study is to determine the impact of hign-flow nasal therapy on pediatric hypercapnic respiratory failure by comparing with nasal continuous positive airway pressure

Conditions

• Respiratory Insufficiency

Interventions

Type	Name	Description
DEVICE	High Flow Nasal Oxygen Therapy	Nasal cannula flows of 3 to 8 lpm via systems approved to provide increased humidification and warmth to inspired gas
DEVICE	Nasal CPAP	Standard nasal CPAP via "bubble" or ventilator support at levels of 4-8 cm H2O

Timeline

• Start date: 2018-01-13
• Primary completion: 2018-11-12
• Completion: 2018-12-01
• First posted: 2018-05-23
• Last updated: 2018-05-29

Locations

1 site across 1 country: China

Regulatory

• FDA-regulated device study