NCT02632799

Airway Pressure During Nasal High Flow and CPAP in Neonates

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: Research Center of Maternal and Child Health Protection, Armenia · Academic / Other
• Sex: All
• Age: 1 Day – 3 Days
• Healthy volunteers: Accepted

Summary

Nasal High Flow (NHF) and CPAP are established forms of respiratory support in neonates and often produce similar clinical outcomes. The aim of the study was to investigate airway pressure during NHF and CPAP in neonates.

Detailed description

Methods: A physiological study which measured pressure intra-nasally with micro (750 µm) pressure probes (Millar, USA) in 10 (5M / 5F) healthy newborns with mean gestation age 37.18 (SD 1.29) wk and mean birth weight of 2414 (SD 503.13) g. NHF was applied at 8 L/min (AIRVO 2) through smaller (OPT 314) and larger (OPT 316) Optiflow nasal cannula; CPAP 5 cmH20 was produced by a Bubble CPAP system and nasal mask interface at constant flow 8 L/min (Fisher \& Paykel Healthcare, NZ). Values are expressed in cmH20 as means and standard deviations (SD).

Conditions

• Respiratory Insufficiency

Interventions

Type	Name	Description
DEVICE	NHF small cannula	NHF 8 l/min by Airvo 2 by small cannula
DEVICE	NHF big cannula	NHF 8 l/min by Airvo 2 by large cannula
DEVICE	CPAP	Nsal CPAP 5cm H2o by face mask

Timeline

• Start date: 2015-01-01
• Primary completion: 2015-08-01
• Completion: 2015-08-01
• First posted: 2015-12-17
• Last updated: 2019-10-31

Locations

2 sites across 1 country: Armenia